Publication date: Available online 15 November 2017
Source:Revue des Maladies Respiratoires
Author(s): F. Pinquié, F. Goupil, J.-P. Oster, A. Dixmier, P.-A. Renault, A. Lévy, J.-P. Mathieu, N. Paillot, F.C. Goutorbe, P. Masson, O. Molinier, D. Debieuvre, M. Grivaux
IntroductionESCAP-2011-CPHG a pour objectif de décrire le traitement du cancer bronchique primitif en pratique quotidienne. Cet article concerne les patients opérés d'un CBNPC.MéthodesDans cette étude de cohorte prospective menée dans 53 hôpitaux généraux, un formulaire standardisé était rempli à chaque changement de stratégie thérapeutique pendant les 2 ans suivant le diagnostic posé en 2010.RésultatsParmi les patients, 3943 étaient inclus, 3418 avaient un CBNPC, 741 (27,1 % ; stade 0-II, IIIA, IIIB, IV : 65 %, 27 %, 3 %, 5 %, respectivement) étaient opérés (chirurgie curative). Les opérés changeaient moins souvent de stratégie thérapeutique et étaient suivis plus longtemps que les non-opérés (suivi moyen : 23,3±9,3 mois vs 10,4±9,5 mois). Parmi les opérés en première stratégie (92,6 % des opérés), 56,9 % n'avaient pas reçu d'autre traitement, 34,7 % avaient une chimiothérapie, 5,9 % une radiochimiothérapie, 2,6 % une radiothérapie. À la fin du suivi, 55,8 % étaient vivants sans autre stratégie, 13,1 % étaient décédés, et 31,1 % avaient reçu au moins un deuxième traitement. Les patients opérés en seconde stratégie avaient bénéficié pour 63 % d'une chimiothérapie seule en première stratégie.ConclusionsESCAP-2011-CPHG permet l'évaluation des pratiques professionnelles dans la prise en charge chirurgicale du CBNPC en hôpital général. Elle met en évidence certaines divergences entre les référentiels nationaux et les stratégies thérapeutiques mises en œuvre dans la « vraie vie ».BackgroundThe aim of ESCAP-2011-CPHG, promoted by the French College of General Hospital Respiratory Physicians, was to describe therapeutic strategies in lung cancer in the first 2 years after diagnosis, in a real-life setting. This article focuses on patients undergoing surgical management of a non-small cell lung cancer (NSCLC).MethodsA prospective multicentre study was conducted in 53 French general hospitals. For each patient with lung cancer diagnosed in 2010, a standardised form was completed following each change in treatment strategy up to 2 years after diagnosis.ResultsOverall, 3418 of the 3943 included patients had NSCLC. 741 patients (21.7%) underwent curative surgery (stage 0-II, IIIA, IIIB, and IV: 65%, 27%, 3% and 5%, respectively). The therapeutic strategy changed less often in surgical than non-surgical patients and average follow-up time was longer: 23.3 months (SD: 9.3) versus 10.4 months (SD: 9.5) for non-surgical patients. Among patients with a surgical first strategy (92.6% of surgical patients as a whole), 56.9% did not receive any other treatment, 34.7% received chemotherapy, 5.9% radio-chemotherapy, 2.6% radiotherapy. At the end of follow-up, 55.8% were still alive without any other strategy, 13.1% had died, and 31.1% had received at least one more strategy. Among patients with a surgical second strategy, 63% had received chemotherapy alone during the first strategy.ConclusionsESCAP -2011- CPHG assessed everyday professional practice in the surgical management of NSCLC in general hospitals. It pointed out the discrepancies between current guidelines and the therapeutic strategies applied in real life conditions.
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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Παρασκευή 17 Νοεμβρίου 2017
Stratégies thérapeutiques chez les patients opérés pour un carcinome bronchique non à petites cellules. Résultats de l’étude ESCAP-2011-CPHG réalisée par le Collège des pneumologues des hôpitaux généraux (CPHG)
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- Response to ‘Clinical presentation of terbinafine-...
- Response to “IL-36 in hidradenitis suppurativa: Ev...
- Chronic sun exposure is associated with distinct h...
- Aprepitant improves refractory pruritus in primary...
- Q-switched 532nm laser energy causes significant v...
- How well are reporting guidelines and trial regist...
- The expanding spectrum of clinical phenotypes asso...
- Response to ‘Clinical presentation of terbinafine-...
- Response to “IL-36 in hidradenitis suppurativa: Ev...
- Chronic sun exposure is associated with distinct h...
- Aprepitant improves refractory pruritus in primary...
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- Hypermethylated ZNF582 and PAX1 genes in oral scra...
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- Sodium chloride pica causing recurrent nephrolithi...
- Metabolic Profile in Patients with Mild Obstructiv...
- Facilitating effects of Buyang Huanwu decoction on...
- Curcuzedoalide contributes to the cytotoxicity of ...
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- The Unexpected Impact of Vaccines on Secondary Bac...
- Victimization and Human Immunodeficiency Virus-Rel...
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- A Slowly Developed Severe Cutaneous Adverse Reacti...
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- Recognizing the haystack is the task of the primar...
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- Bi-orifice approach to nasal intubation in childre...
- The effect of sevoflurane compared to propofol mai...
- A case of midazolam anaphylaxis during a pediatric...
- Anesthetic management of a patient with benign tra...
- Intermittent bilateral anterior sub-costal quadrat...
- A novel approach for performing ultrasound-guided ...
- Combined spinal epidural in a parturient with tine...
- Postpartum tubal ligation: A retrospective review ...
- Surgeon assisted quadratus lumborum block – ‘Gaura...
- Anesthetic management for retrieval of a large asp...
- Reversal of trend in near infrared spectroscopy [N...
- Strategies to prevent ischemic optic neuropathy fo...
- Medicaid insurance as primary payer predicts incre...
- Incidence of complications in the post-anesthesia ...
- Measuring satisfaction and anesthesia related outc...
- Paraneuraxial Nerve Blocks: A well-defined novel t...
- Emergency surgery in a newborn patient with severe...
- Postpartum infective endocarditis with Enterococcu...
- Two Scientific Awards for papers published in Slee...
- Editorial Board
- Effect of laser activated bleaching on the chemica...
- New roles and controls of mast cells
- Recent advances in inflammasome biology
- Type I interferon-mediated autoinflammation and au...
- Mechanisms of propofol attenuation of ketamine-ind...
- Lumbar Spine Anatomy in Women Sustaining Unintenti...
- Postpartum infective endocarditis with Enterococcu...
- Using Citrus aurantifolia essential oil for the po...
- Intrapartum assessment of fetal well-being
- Treatment withdrawal and end-of-life care in the i...
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