TiF4 incorporated into a self-etching primer in different concentrations: antimicrobial properties and effects on demineralization inhibition around the enamel-dentin/restoration interface

Publication date: Available online 3 November 2017
Source:Archives of Oral Biology
Author(s): G.L. Abbatepaulo, T.M.M.C. Gangana, E.F. Martinez, C.P. Turssi, FMG França, F.L.B. Amaral, R.T. Basting
PurposeTo evaluate the antimicrobial effect by minimum bactericidal concentration (MBC) of titanium tetrafluoride (TiF4) in an aqueous solution (AS) or incorporated into the primer (P) of a self-etching adhesive system against Streptococcus mutans (Sm) and Lactobacillus casei (Lc); the effect of dentin pre-treatment with TiF4 in an AS or incorporated into the P of CL regarding the potential to inhibit the development of carious lesions at the restoration interface.Materials and methodsFor MBC, AS or P with different concentrations (in %) of TiF4 were used (from 0.0 to 4.0). Also, 50 cavities were prepared at the enamel/dentin junction of third molars, which received the dentin pre-treatments (n=10): Clearfil SE Bond (CL); AS of 2.5%TiF4+CL (AS2.5%); AS of 4%TiF4+CL (AS4%); 2.5%TiF4 incorporated into the P (P2.5%); 4%TiF4 incorporated into the P (P4%). Cavities were restored and submitted to pH cycling for artificial caries lesions induction. Microhardness tests were performed after sectioning the restorations to assess the presence of demineralization in margins.ResultsANOVA and Tukey tests showed that TiF4 in AS presented MBC against Sm and Lc over 2.0%. TiF4 into the P of a self-ething adhesive presented MBC over 1% for Lc. For enamel, CL showed no significant differences in microhardness between the depths.ConclusionsAS had an antimicrobial effect against Sm and Lc over 2.0%. Pretreatment with AS or P did not promote inhibition of demineralization at enamel or dentin restoration interfaces.



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