Contemporary management of high-grade gliomas.

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Contemporary management of high-grade gliomas.

CNS Oncol. 2017 Dec 15;:

Authors: Sim HW, Morgan ER, Mason WP

Abstract
High-grade gliomas, including glioblastoma, are the most common malignant brain tumors in adults. Despite intensive efforts to develop new therapies for these diseases, treatment options remain limited and prognosis is poor. Recently, there have been important advances in our understanding of the molecular basis of glioma, leading to refinements in our diagnostic and management approach. There is new evidence to guide the treatment of elderly patients. A multitude of new agents have been investigated, including targeted therapies, immunotherapeutics and tumor-treating fields. This review summarizes the key findings from this research, and presents a perspective on future opportunities to advance the field.

PMID: 29241354 [PubMed - as supplied by publisher]

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