Circadian Clocks and UPR: New Twists as the Story Unfolds

Publication date: 8 January 2018
Source:Developmental Cell, Volume 44, Issue 1
Author(s): Nikolay B. Milev, David Gatfield
Circadian clocks help control the unfolded protein response (UPR). In a recent issue of Nature Cell Biology, Bu et al. (2017) show that the interaction is reciprocal, with miRNA-211 providing a signal from the UPR to the clock component BMAL1, affecting circadian timing, global translational control, and cancer cell survival.

Teaser

Circadian clocks help control the unfolded protein response (UPR). In a recent issue of Nature Cell Biology, Bu et al. (2017) show that the interaction is reciprocal, with miRNA-211 providing a signal from the UPR to the clock component BMAL1, affecting circadian timing, global translational control, and cancer cell survival.


http://ift.tt/2mgf2nd