Acute Effects of Low-Level Laser Therapy on Patients' Functional Capacity in the Postoperative Period of Coronary Artery Bypass Graft Surgery: A Randomized, Crossover, Placebo-Controlled Trial.

Related Articles

Acute Effects of Low-Level Laser Therapy on Patients' Functional Capacity in the Postoperative Period of Coronary Artery Bypass Graft Surgery: A Randomized, Crossover, Placebo-Controlled Trial.

Photomed Laser Surg. 2018 Feb 21;:

Authors: Stein C, Fernandes RO, Miozzo AP, Coronel CC, Baroni BM, Belló-Klein A, Plentz RDM

Abstract
OBJECTIVE: The aim of this study was to evaluate the acute effects of low-level laser therapy (LLLT) on the functional capacity to exercise tested by incremental shuttle walking test (ISWT) after coronary artery bypass graft (CABG) surgery.
METHODS: Fifteen male patients (60 ± 9 years) were crossed over during the experiment, to compare the outcomes after active LLLT and placebo LLLT treatments. LLLT (850 nm, 200 mW, 30 J to each point, resulting in a total of 240 J per quadriceps muscle), using a multidiode cluster (five spots; 6 J/spot) in eight points per leg was performed 3 min before the ISWT. We analyzed distance walked, Borg scale of perceived exertion, heart rate, and brachial arterial blood pressure. Markers of tissue damage (lactate dehydrogenase [LDH]) and oxidative stress (lipid peroxidation, total thiol levels, and antioxidant enzyme activity of superoxide dismutase [SOD] and catalase [CAT]) were also measured in peripheral blood.
RESULTS: Comparison of the distances walked revealed no significant differences between the LLLT and placebo LLLT groups (p = 0.779). Regarding the Borg scale (p = 0.567), heart rate (p = 0.506) as well as systolic and diastolic blood pressure (p = 0.164 and p = 0.140, respectively), no differences were observed between LLLT and placebo LLLT groups. Application of LLLT was not able to change levels of LDH (p = 0.214), oxidative lipid damage (p = 0.733), total thiol levels (p = 0.925), SOD (p = 0.202), and CAT (p = 0.825) enzyme activities.
CONCLUSIONS: Acute LLLT improved neither functional capacity to exercise nor the markers of oxidation after CABG.
TRIAL REGISTRATION: Registered as a clinical trial (NCT02688426).

PMID: 29466116 [PubMed - as supplied by publisher]

http://ift.tt/2GCT71b