Publication date: Available online 22 June 2018
Source:Revue des Maladies Respiratoires
Author(s): M. Underner, A. Cuvelier, G. Peiffer, J. Perriot, N. Jaafari
IntroductionLes exacerbations sont fréquentes au cours de la bronchopneumopathie chronique obstructive (BPCO) et contribuent à la morbidité et la mortalité de la maladie. La BPCO est également associée à une prévalence élevée de l'anxiété et de la dépression.ObjectifsRevue systématique de la littérature à propos des données concernant l'association entre anxiété, dépression et exacerbations de la BPCO.Sources documentairesMedline sur la période 1980–2017 avec pour mots-clés : chronic obstructive pulmonary disease ou COPD et exacerbation et anxiety ou depression, avec les limites title/abstract ; les langues retenues étaient l'anglais et le français.RésultatsParmi 152 articles, 77 résumés sélectionnés ont donné lieu à une double lecture aboutissant à retenir 30 études. La prévalence de l'anxiété et de la dépression variait de 6,7 à 58 % et de 5,5 à 51,5 %, respectivement. Parmi les 30 études de cette revue, 19 (63,3 %) retrouvaient une association positive entre l'anxiété et/ou la dépression et une augmentation du risque d'exacerbations, alors que les 11 autres (36,7 %) ne retrouvaient pas une telle association. L'association entre l'anxiété et/ou la dépression et une augmentation du risque d'exacerbations était beaucoup plus souvent observée dans les études utilisant une définition des exacerbations basée sur les événements (85,7 %) que dans celles basée sur les symptômes (14,3 %). La principale limite de cette revue est l'importante hétérogénéité des études incluses. Une autre limite est la faible proportion de femmes qui y étaient incluses (32,6 %).ConclusionL'anxiété et/ou la dépression semblent augmenter le risque d'exacerbations de la BPCO. Toutefois, l'importante hétérogénéité des études fait qu'il est difficile de tirer des conclusions définitives sur cette augmentation de risque.IntroductionExacerbations are common during the course of chronic obstructive pulmonary disease (COPD) and contribute to its morbidity and mortality. COPD is also associated with high prevalence of anxiety and depression.ObjectivesA systematic literature review of data on the association between anxiety and/or depression and COPD exacerbations.Documentary sourcesMedline search, for the 1980–2017 period, with the following keywords: "chronic obstructive pulmonary disease" or "COPD" and "exacerbation" and "anxiety" or "depression"; limits: "title/abstract"; the selected languages were English or French.ResultsAmong 152 articles, 77 abstracts have been preselected for a dual reading and 30 studies have been finally selected. The prevalence of anxiety and depression ranged from 6.7 to 58% and 5.5 to 51.5%, respectively. Among the 30 studies included in this review, 19 (63.3%) revealed positive associations between anxiety and/or depression and increased risk for exacerbations, although 11 (36.7%) failed to support such an association. The association between anxiety and/or depression and an increased risk of COPD exacerbations was more frequently observed in studies using an event-based definition (85.7%) than in those using a symptom-based definition (14.3%). The main limitation of this review is the high heterogeneity of the studies included. Another limitation is the low rate of women included in this review (32.6%).ConclusionAnxiety and/or depression are associated with a greater risk for exacerbations to occur in COPD. However, a high heterogeneity across the published studies makes it difficult to draw any firm conclusions on the amplitude of this increased risk.
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Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
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Influence de l’anxiété et de la dépression sur les exacerbations au cours de la BPCO
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