Omalizumab chronic spontaneous urticaria: efficacy, safety, predictors of treatment outcome and time to response

Chronic spontaneous urticaria (CSU) is the most common subtype of urticaria, and is characterized by recurrent episodes of spontaneous wheals and/or angioedema with unknown triggers, lasting for more than six weeks.1 CSU generally affects 0.5–1.0% of people 20–40 years of age, with a disease duration of 1–5 years.2 Patients with CSU often experience sleep deprivation and psychiatric comorbidities like anxiety and depression, which compromise the health-related and overall quality of life of the affected individuals.

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