Perioperative intermediate care units (termed surgical special care units) have been widely implemented across health systems because they are believed to improve surveillance and management of high-risk surgical patients. Our objective was to conduct a systematic review to investigate the effects of a 3-level model of perioperative care delivery (ie, ward, surgical special care unit, or intensive care unit) compared to a 2-level model of care (ie, ward, intensive care unit) on postoperative outcomes. Our protocol was registered with PROSPERO, the international prospective register of systematic reviews (CRD42015025155). Randomized controlled studies and nonrandomized comparator studies were included. We performed a systematic search of Medline, Cumulative Index to Nursing and Allied Health Literature, Embase, and the Cochrane library (inception – 11/2017). The primary outcome was mortality; secondary outcomes included length of stay and hospital costs. We identified 1995 citations with our search, and 21 studies met eligibility criteria (2 randomized controlled studies and 19 nonrandomized comparator studies; 44,134 patients in total). Surgical special care units were characterized by continuous monitoring (12 studies), the absence of mechanical ventilation (8 studies), nurse-to-patient ratios (range, 1:2–1:4), and number of beds (median: 5; range: 3–33). Thirteen studies reported on mortality. Notable findings included no observed difference in overall in-hospital mortality, but an apparent increase in intensive care unit mortality in a 3-level model of care. This may reflect a decanting of lower acuity patients from the intensive care unit to the surgical special care unit. No significant difference was found in hospital length of stay; however, 2 studies demonstrated reductions in hospital costs with the implementation of a surgical special care unit. Significant clinical and methodological heterogeneity precluded pooled analysis. Given the prevalence of surgical special care units, the results of our review suggest that additional methodologically rigorous investigations are needed to understand the effect of these units on the surgical population. Accepted for publication October 8, 2018. Funding: M.M.L. and D.I.M. are supported by the Ottawa Hospital Alternate Funds Association, Ottawa, Ontario, Canada. M.M.L. is also supported by Scholarship Protected Time Program, Department of Anesthesiology and Pain Medicine, Ottawa, Ottawa, Ontario, Canada. Conflicts of Interest: See Disclosures at the end of the article. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's website (http://bit.ly/KegmMq). Reprints will not be available from the authors. Address correspondence to Manoj M. Lalu, MD, PhD, FRCPC, Department of Anesthesiology and Pain Medicine, Clinical Epidemiology and Regenerative Medicine Programs, Blueprint Translational Research Group, Ottawa Hospital Research Institute, 501 Smyth Rd, PO Box 201B, Ottawa, ON K1H 8L6, Canada. Address e-mail to manojlalu@gmail.com. © 2019 International Anesthesia Research Society
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- Low Tidal Volume Ventilation in the Surgical Patie...
- In Response
- Regional Anesthesia for Pediatric Ophthalmic Surge...
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- Metabolic tumor volume and total lesion glycolysis...
- Radioiodine Uptake and Thyroglobulin-Guided Radioi...
- Leslie J. De Groot (September 20, 1928–October 3, ...
- Future Meetings
- Correction to: Diagnostic Performance of Ultrasoun...
- Unfavorable Socioeconomic Factors Underlie High Ra...
- Association Between Diethylhexyl Phthalate Exposur...
- Occurrence, sources and effects of polycyclic arom...
- Disparities persist in asthma-related emergency de...
- Ethanol LOCK & Immunoglobulin LOAD: Improving the ...
- New IgE Immediate Hypersensitivity Reactions Upon ...
- A Peripheral Cause of Asthma: Peripheral T-cell Ly...
- The Evaluation of Tryptase after Subcutaneous Immu...
- Evaluation of the antifungal activity of individua...
- Interactive effect of potassium and flyash: a soil...
- A simple code for efficient indicative number reco...
- Neural Switch Asymmetry in Feature-Based Auditory ...
- New Options Emerging for Painful Abscesses, Skin S...
- A potential role for peripheral natural killer cel...
- Predictive value of FHIT, p27, and pERK1/ERK2 in s...
- Fludroxycortide cream as an alternative therapy fo...
- To Be Cautious or Not: Tension Pneumothorax After ...
- Scanning electron microscopy analysis of aligner f...
- Systemic Treatment for Clinically Amyopathic Derma...
- Association of HLA Antigen Mismatch With Risk of P...
- Arthropathy and Cutaneous Eruption in a Patient Wi...
- Flexural Eruption Associated With Arsenic Trioxide...
- Targeted Treatment of TREX1 Chilblain Lupus and Ot...
- Assessment of Clinical Response to JAK Inhibition ...
- Evaluation of Compendia for Part D Coverage Determ...
- Following in the footsteps of Hippocrates—interrel...
- Scanning electron microscopy analysis of aligner f...
- Phthalate exposure and cumulative risk in a Chines...
- Topical Retinoids in Acne Vulgaris: A Systematic R...
- New Vision in Photoprotection and Photorepair
- Expression, Localization, and Regulation of the So...
- Alterations in the intestinal microbiota of patien...
- A comparative study on the photo-catalytic degrada...
- Pru p 7 sensitisation is a predominant cause of se...
- Kimura’s Disease: A Diagnostic and Therapeutic Cha...
- An Immunohistochemical Study of HIF-1 Alpha in Ora...
- Recurrent Bell's palsy
- Our experience of shorter stay and lower cost for ...
- Validation of french versions of the facial disabi...
- Therapeutic effects of the selective farnesoid X r...
- From sensory circumventricular organs to cerebral ...
- A fiber coherence index for quality control of B-t...
- Development of a Novel Approach to Studying Corneo...
- Hypereosinophilic syndrome presenting with bilater...
- Abnormal fronto-striatal intrinsic connectivity re...
- “Looks familiar, but I do not know who she is”: Th...
- The role of the hippocampus in weighting expectati...
- Cost‐effectiveness analysis of screen‐and‐treat st...
- The risk of Helicobacter pylori infection for adve...
- Cost‐effectiveness analysis of screen‐and‐treat st...
- The risk of Helicobacter pylori infection for adve...
- Global Analysis of Lysine Succinylome in the Perio...
- Decreased Treg-derived miR-181a and miR-155 correl...
- Editorial Board
- Editorial Board
- Motivations Among Sexual‐Minority Men for Starting...
- Comment on “Diagnostic accuracy of ex vivo fluores...
- Therapeutic Pearl: Regenerative Healing Ability of...
- The use of Virtual Reality for Bedside Procedures
- Understanding the experience of sleep disturbance ...
- Editorial Board and Contents
- Motivations Among Sexual‐Minority Men for Starting...
- Comment on “Diagnostic accuracy of ex vivo fluores...
- The use of Virtual Reality for Bedside Procedures
- Understanding the experience of sleep disturbance ...
- Port-wine stains on the neck respond better to a p...
- Letter to the Editor: Nail Lichen Planus: A True N...
- Screening for Depression and Suicidality in Psoria...
- Nail lichen planus
- Rule of thumb: a simple tool to estimate 1% scalp ...
- The Most Common Causes of Burnout among U.S. Acade...
- Primary Cutaneous Hodgkin‐like Polymorphic Post‐Tr...
- Long‐term efficacy and safety of secukinumab in Ja...
- Case of cutaneous myoepithelioma managed with surg...
- Successful treatment of unresectable recurrent pro...
- Results of a retrospective study on the efficacy a...
- Elevation of serum interleukin‐21 in patients with...
- A cross-sectional evaluation of outcomes of pediat...
- Acute otitis media in infants younger than two mon...
- Metastatic Cellular Neurothekeoma in Childhood
- Endoscopic Arytenoid Abduction Lateropexy for the ...
- Prospective analysis of mid-facial fractures in a ...
- Impact of allergic rhinitis on quality of life aft...
- N-acetyl cysteine versus chlorhexidine mouthwashes...
- Development of herpes zoster during infliximab tre...
- Surgical management of nasal dermoid lesions
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