Nonclassical pemphigus with exclusively IgG anti‐desmocollin 3‐specific antibodies

Abstract

We describe a patient with nonclassical clinical and histopathological features of pemphigus with exclusively IgG antibodies against desmocollin (Dsc) 3 detected by enzyme‐linked immunosorbent assay of recombinant eukaryotic protein of Dsc1‐Dsc3. The absence of antibodies against other known targets, such as desmogleins, reinforces the role of anti‐Dsc antibodies in the pathophysiology of atypical pemphigus.

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