Acne relapses: impact on quality of life and productivity

Abstract

Background

Acne is a common skin disease that mostly affects teenagers, with a negative impact on quality of life. Recently, adult acne and acne relapses have increased in frequency, for yet unknown reasons.

Objective

This non‐interventional, real‐life study sought to investigate the rate of acne relapses, and their impact on quality of life and productivity (loss/absenteeism) among teenagers and adults.

Methods

An online self‐administered questionnaire was proposed to ≥15‐year‐olds suffering from acne who spontaneously consulted their dermatologist. To ensure homogeneous assessment of acne severity, the Global Acne Severity (GEA) scale was applied. Quality of life was assessed via Cardiff Acne Disability Index (CADI), SF12‐physical score (PS), and SF12‐mental score (MS) questionnaires. Productivity loss or absenteeism in middle/high school was estimated based on the number of days off work or school over the last 30 days.

Results

Overall, 1,048 questionnaires were considered assessable, with 448 (43%) mild acne, 434 (41%) moderate acne, and 166 (16%) severe acne. Overall, 755 (72%) participants were in middle/high school, 267 (25%) employed, and 26 (3%) with no professional activity. Considering the population by age groups, 68% (n = 716) were ≤20‐year‐olds and 32% (n = 332) >20‐year‐olds, with a mean age of 20.26 (SD: 7.43) years. Acne relapses were reported by 44% of respondents. Analyses revealed that poorer quality of life scores were observed in acne relapsers versus non‐relapsers, with a significant difference for CADI scores (p <0.01) in >20‐year‐olds. Acne‐related absenteeism was recorded in 5.7% of cases. On multivariate analyses, after adjusting for other variables, acne relapse was proven a significant determinant of absenteeism/productivity loss.

Conclusion

This real‐life study first demonstrated acne relapse rates of 44%, which appeared to be generation‐dependent, affecting 39.9% of ≤20‐year‐olds versus 53.3% of >20‐year‐olds. Acne relapses were significantly associated with impaired quality of life and productivity loss/absenteeism.

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