Another Look at Cyclosporine for Treating Antihistamine-Resistant Chronic Spontaneous Urticaria

There are only two treatments with demonstrated efficacy in randomized placebo controlled clinical trials for antihistamine-resistant chronic spontaneous urticaria (CSU), cyclosporine1 and omalizumab.2 The latter is a commercial product that was well studied to obtain FDA approval for marketing as a treatment for CSU within the past 5 years. Cyclosporine is a generic drug that was first demonstrated in a randomized placebo controlled trial to be an effective treatment for CSU almost 20 years ago,1

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