Antibiotics, Vol. 9, Pages 662: Antimicrobial Resistance in Fecal Escherichia coli from Humans and Pigs at Farms at Different Levels of Intensification Antibiotics doi: 10.3390/antibiotics9100662 Authors: Kamonwan Lunha Thongpan Leangapichart Jatesada Jiwakanon Sunpetch Angkititrakul Marianne Sunde Josef D. Järhult Gunilla Ström Hallenberg Rachel A. Hickman Thomas Van Boeckel Ulf Magnusson The overall aim of the current study was to test the hypotheses that...
Wed Sep 30, 2020 03:00
Antibiotics, Vol. 9, Pages 663: From Orphan Phage to a Proposed New Family–the Diversity of N4-Like Viruses Antibiotics doi: 10.3390/antibiotics9100663 Authors: Johannes Wittmann Dann Turner Andrew D. Millard Padmanabhan Mahadevan Andrew M. Kropinski Evelien M. Adriaenssens Escherichia phage N4 was isolated in 1966 in Italy and has remained a genomic orphan for a long time. It encodes an extremely large virion-associated RNA polymerase unique for bacterial viruses that...
Wed Sep 30, 2020 03:00
Antibiotics, Vol. 9, Pages 661: Caerin 1 Antimicrobial Peptides That Inhibit HIV and Neisseria May Spare Protective Lactobacilli Antibiotics doi: 10.3390/antibiotics9100661 Authors: Louise A. Rollins-Smith Patricia B. Smith Anna M. Ledeczi Julia M. Rowe Laura K. Reinert Although acquired immunodeficiency syndrome (AIDS) caused by the human immunodeficiency virus (HIV) is a manageable disease for many, it is still a source of significant morbidity and economic hardship for...
Wed Sep 30, 2020 03:00
Antibiotics, Vol. 9, Pages 657: Enterococcus faecalis Endocarditis and Outpatient Treatment: A Systematic Review of Current Alternatives Antibiotics doi: 10.3390/antibiotics9100657 Authors: Laura Herrera-Hidalgo Arístides de Alarcón Luis E. López-Cortes Rafael Luque-Márquez Luis F. López-Cortes Alicia Gutiérrez-Valencia María V. Gil-Navarro The selection of the best alternative for Enterococcus faecalis infective endocarditis (IE) continuation treatment in the outpatient...
Wed Sep 30, 2020 03:00
Antibiotics, Vol. 9, Pages 659: MeJA Elicitation of Chicory Hairy Roots Promotes Efficient Increase of 3,5-diCQA Accumulation, a Potent Antioxidant and Antibacterial Molecule Antibiotics doi: 10.3390/antibiotics9100659 Authors: Guillaume Bernard Harmony Alves Dos Alves Dos Santos Audrey Etienne Jennifer Samaillie Christel Neut Sevser Sahpaz Jean-Louis Hilbert David Gagneul Nathalie Jullian Ali Tahrioui Sylvie Chevalier Céline Rivière Caroline Rambaud ...
Wed Sep 30, 2020 03:00
Antibiotics, Vol. 9, Pages 658: Synergistic Therapies as a Promising Option for the Treatment of Antibiotic-Resistant Helicobacter pylori Antibiotics doi: 10.3390/antibiotics9100658 Authors: Paweł Krzyżek Emil Paluch Grażyna Gościniak Helicobacter pylori is a Gram-negative bacterium responsible for the development of gastric diseases. The issue of spreading antibiotic resistance of H. pylori and its limited therapeutic options is an important topic in modern gastroenterology. This...
Wed Sep 30, 2020 03:00
Antibiotics, Vol. 9, Pages 660: Characterization of Multidrug Resistance Patterns of Emerging Salmonella enterica Serovar Rissen along the Food Chain in China Antibiotics doi: 10.3390/antibiotics9100660 Authors: Xuebin Xu Silpak Biswas Guimin Gu Mohammed Elbediwi Yan Li Min Yue Salmonella spp. are recognized as important foodborne pathogens globally. Salmonella enterica serovar Rissen is one of the important Salmonella serovars linked with swine products in numerous countries...
Wed Sep 30, 2020 03:00
Antioxidants, Vol. 9, Pages 939: The Glyoxalase System—New Insights into an Ancient Metabolism Antioxidants doi: 10.3390/antiox9100939 Authors: Jakob Morgenstern Marta Campos Campos Peter Nawroth Thomas Fleming The glyoxalase system was discovered over a hundred years ago and since then it has been claimed to provide the role of an indispensable enzyme system in order to protect cells from a toxic byproduct of glycolysis. This review gives a broad overview of what has been postulated...
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Antioxidants, Vol. 9, Pages 938: The Combined Effect of Mediterranean Shrubland Pasture and the Dietary Administration of Sage By-Products on the Antioxidant Status of Segureña Ewes and Lambs Antioxidants doi: 10.3390/antiox9100938 Authors: María J. Jordán Cristina Martínez-Conesa Sancho Bañón Julio Otal María Quílez Inmaculada García-Aledo Pascual Romero-Espinar Pedro Sánchez-Gómez The objective of this study was to determine if the combined effect of ewe grazing...
Wed Sep 30, 2020 03:00
Atmosphere, Vol. 11, Pages 1049: Impacts of the Tropical Pacific–Indian Ocean Associated Mode on Madden–Julian Oscillation over the Maritime Continent in Boreal Winter Atmosphere doi: 10.3390/atmos11101049 Authors: Xin Li Ming Yin Xiong Chen Minghao Yang Fei Xia Lifeng Li Guangchao Chen Peilong Yu Chao Zhang Based on the observation and reanalysis data, the relationship between the Madden–Julian Oscillation (MJO) over the Maritime Continent (MC) and...
Wed Sep 30, 2020 03:00
Atmosphere, Vol. 11, Pages 1050: Tribological and Emission Behavior of Novel Friction Materials Atmosphere doi: 10.3390/atmos11101050 Authors: Ana Paula Gomes Nogueira Davide Carlevaris Cinzia Menapace Giovanni Straffelini The tribological behavior and the related airborne particles emission of three copper-free automotive friction materials are investigated. The tests were conducted using a pin-on-disc tribometer equipped with a specifically designed clean-enclosure chamber...
Wed Sep 30, 2020 03:00
Atmosphere, Vol. 11, Pages 1047: Framing Climate Services: Logics, Actors, and Implications for Policies and Projects Atmosphere doi: 10.3390/atmos11101047 Authors: Marine Lugen This paper explores how climate services are framed in the literature and possible implications for climate services’ policies and projects. By critically exploring the frames around climate services, the wider objective is to encourage more reflexive and responsible research in the field, particularly...
Wed Sep 30, 2020 03:00
Atmosphere, Vol. 11, Pages 1048: Cost-Benefit Analysis for Single and Double Rice Cropping Systems under the Background of Global Warming Atmosphere doi: 10.3390/atmos11101048 Authors: Qing Ye Xiaoguang Yang Yong Li Wanghua Huang Wenjuan Xie Tianying Wang Yan Wang Global warming might expand crop growth areas for the prevailing single and double rice cropping systems in Southern China. Based on historical weather and crop data from 1981 to 2015, we evaluated the economic...
Wed Sep 30, 2020 03:00
Atmosphere, Vol. 11, Pages 1046: Daily Variability in the Terrestrial UV Airglow Atmosphere doi: 10.3390/atmos11101046 Authors: Thomas J. Immel Richard W. Eastes William E. McClintock Steven B. Mende Harald U. Frey Colin Triplett Scott L. England New capability for observing conditions in the upper atmosphere comes with the implementation of global ultraviolet (UV) imaging from geosynchronous orbit. Observed by the NASA GOLD mission, the emissions of atomic oxygen (OI)...
Wed Sep 30, 2020 03:00
Atmosphere, Vol. 11, Pages 1045: Spread of COVID-19, Meteorological Conditions and Air Quality in the City of Buenos Aires, Argentina: Two Facets Observed during Its Pandemic Lockdown Atmosphere doi: 10.3390/atmos11101045 Authors: Tomás R. Bolaño-Ortiz Romina M. Pascual-Flores S. Enrique Puliafito Yiniva Camargo-Caicedo Lucas L. Berná-Peña María F. Ruggeri Ana I. Lopez-Noreña María F. Tames Francisco Cereceda-Balic This work studied the spread of COVID-19, the...
Wed Sep 30, 2020 03:00
Atmosphere, Vol. 11, Pages 1044: Analyses of Climate Variations at Four Meteorological Stations on Remote Islands in the Croatian Part of the Adriatic Sea Atmosphere doi: 10.3390/atmos11101044 Authors: Ognjen Bonacci Matko Patekar Marco Pola Tanja Roje-Bonacci The Mediterranean region is one of the regions in the world that is most vulnerable to the impact of imminent climate change. In particular, climate change has an adverse effect on both the ecosystem and socioeconomic...
Wed Sep 30, 2020 03:00
Beverages, Vol. 6, Pages 59: Effect of 1-Methylcyclopropene (1-MCP) and Storage Atmosphere on the Volatile Aroma Composition of Cloudy and Clear Apple Juices Beverages doi: 10.3390/beverages6040059 Authors: Bizuayehu M. Muche Michael Jordan Charles F. Forney R. Alex Speers H. P. Vasantha Rupasinghe The effects of 1-methylcyclopropene (1-MCP), storage atmosphere (controlled (CA) or regular (RA)), and juice processing (clear or cloudy) on the volatile aroma compounds from McIntosh...
Wed Sep 30, 2020 03:00
Bioengineering, Vol. 7, Pages 119: Cell Scaffolds for Bone Tissue Engineering Bioengineering doi: 10.3390/bioengineering7040119 Authors: Kazutoshi Iijima Hidenori Otsuka Currently, well-known surgical procedures for bone defects are classified into four types: (1) autogenous bone graft transplantation, (2) allogeneic bone graft transplantation, (3) xenogeneic bone graft transplantation, and (4) artificial bone graft transplantation. However, they are often risky procedures and related...
Wed Sep 30, 2020 03:00
Bioengineering, Vol. 7, Pages 118: Next Stage Approach to Tissue Engineering Skeletal Muscle Bioengineering doi: 10.3390/bioengineering7040118 Authors: Gregory Reid Fabio Magarotto Anna Marsano Michela Pozzobon Large-scale muscle injury in humans initiates a complex regeneration process, as not only the muscular, but also the vascular and neuro-muscular compartments have to be repaired. Conventional therapeutic strategies often fall short of reaching the desired functional outcome,...
Wed Sep 30, 2020 03:00
Biology, Vol. 9, Pages 317: Sourcing and Propagation of Pontechium maculatum for Horticulture and Species Restoration Biology doi: 10.3390/biology9100317 Authors: Barbara Nowak Ewa Sitek Joanna Augustynowicz Pontechium maculatum, a species of ornamental, apicultural, health and medicinal value, is threatened in some Central European countries including Poland. Its propagation using seeds or in vitro techniques is needed for multiple applications including conservation. Generative...
Wed Sep 30, 2020 03:00
Biology, Vol. 9, Pages 314: Cholesterol Homeostasis: An In Silico Investigation into How Aging Disrupts Its Key Hepatic Regulatory Mechanisms Biology doi: 10.3390/biology9100314 Authors: Amy Elizabeth Morgan Mark Tomás Mc Auley The dysregulation of intracellular cholesterol homeostasis is associated with several age-related diseases, most notably cardiovascular disease (CVD). Research in this area has benefitted from using computational modelling to study the inherent complexity associated...
Wed Sep 30, 2020 03:00
Biology, Vol. 9, Pages 316: Systematic Ancient DNA Species Identification Fails to Find Late Holocene Domesticated Cattle in Southern Africa Biology doi: 10.3390/biology9100316 Authors: K. Ann Horsburgh Anna L. Gosling Establishing robust temporal control of the arrival of domesticated stock and the associated husbandry skills and lifeways in Southern Africa remains frustrated by the osteological similarities between domestic stock and wild endemic fauna. We report the results of...
Wed Sep 30, 2020 03:00
Biomedicines, Vol. 8, Pages 390: Supplementing Glycine and N-acetylcysteine (GlyNAC) in Aging HIV Patients Improves Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Endothelial Dysfunction, Insulin Resistance, Genotoxicity, Strength, and Cognition: Results of an Open-Label Clinical Trial Biomedicines doi: 10.3390/biomedicines8100390 Authors: Premranjan Kumar Chun Liu James W. Suliburk Charles G. Minard Raja Muthupillai Shaji Chacko Jean W. Hsu Farook Jahoor Rajagopal...
Wed Sep 30, 2020 03:00
Biomimetics, Vol. 5, Pages 46: Design of a Carangiform Swimming Robot through a Multiphysics Simulation Environment Biomimetics doi: 10.3390/biomimetics5040046 Authors: Daniele Costa Giacomo Palmieri Matteo-Claudio Palpacelli David Scaradozzi Massimo Callegari Bio-inspired solutions devised for autonomous underwater robots are currently being investigated by researchers worldwide as a way to improve propulsion. Despite efforts to harness the substantial potential payoffs...
Wed Sep 30, 2020 03:00
Biomolecules, Vol. 10, Pages 1398: The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function Biomolecules doi: 10.3390/biom10101398 Authors: Montaseri Giampietri Rossi Riccioli Fattore Filippini Autophagy is an evolutionary conserved and highly regulated recycling process of cellular wastes. Having a housekeeping role, autophagy through the digestion of domestic cytosolic organelles, proteins, macromolecules, and pathogens, eliminates unnecessary...
Wed Sep 30, 2020 03:00
Biomolecules, Vol. 10, Pages 1397: Molecular Action of Hydroxytyrosol in Wound Healing: An In Vitro Evidence-Based Review Biomolecules doi: 10.3390/biom10101397 Authors: Nike Dewi Utami Abid Nordin Haliza Katas Ruszymah Bt Hj Idrus Mh Busra Fauzi Hydroxytyrosol (HT) is an essential molecule isolated from the phenolic fraction of olive (Olea europaea). HT has been implicated for its health-stimulating effect mainly due to its antioxidative capacity. The current review summarises...
Wed Sep 30, 2020 03:00
Biomolecules, Vol. 10, Pages 1394: Anti-Obesity Effects of Soybean Embryo Extract and Enzymatically-Modified Isoquercitrin Biomolecules doi: 10.3390/biom10101394 Authors: Minsu Kim Seowoo Im Yoon keun Cho Cheoljun Choi Yeonho Son Doyoung Kwon Young-Suk Jung Yun-Hee Lee Soy isoflavones are bioactive phytoestrogens with known health benefits. Soybean embryo extract (SEE) has been consumed as a source of isoflavones, mainly daidzein, glycitein, and genistein. While...
Wed Sep 30, 2020 03:00
Biomolecules, Vol. 10, Pages 1396: The Emerging Role of MicroRNAs in Regulating the Drug Response of Cholangiocarcinoma Biomolecules doi: 10.3390/biom10101396 Authors: Wen-Kuan Huang Chun-Nan Yeh Cholangiocarcinoma (CCA) is the most common biliary malignancy, and has a poor prognosis. The median overall survival with the standard-of-care chemotherapy (Gemcitabine and cisplatin) in patients with advanced-stage CCA is less than one year. The limited efficacy of chemotherapy or targeted...
Wed Sep 30, 2020 03:00
Biomolecules, Vol. 10, Pages 1395: Targeting Mitochondria in Melanoma Biomolecules doi: 10.3390/biom10101395 Authors: Sepideh Aminzadeh-Gohari Daniela D. Weber Luca Catalano René G. Feichtinger Barbara Kofler Roland Lang Drastically elevated glycolytic activity is a prominent metabolic feature of cancer cells. Until recently it was thought that tumor cells shift their entire energy production from oxidative phosphorylation (OXPHOS) to glycolysis. However, new evidence...
Wed Sep 30, 2020 03:00
Biomolecules, Vol. 10, Pages 1393: Identification of Plasma Glycosphingolipids as Potential Biomarkers for Prostate Cancer (PCa) Status Biomolecules doi: 10.3390/biom10101393 Authors: Ashley J. Snider Michael C. Seeds Laurel Johnstone Justin M. Snider Brian Hallmark Rahul Dutta Cristina Moraga Franco John S. Parks Jeannette T. Bensen Corey D. Broeckling James L. Mohler Gary J. Smith Elizabeth T.H. Fontham Hui-Kuan Lin William Bresette Susan Sergeant...
Wed Sep 30, 2020 03:00
Biosensors, Vol. 10, Pages 139: Screen-Printed Electrode-Based Sensors for Food Spoilage Control: Bacteria and Biogenic Amines Detection Biosensors doi: 10.3390/bios10100139 Authors: Ricarda Torre Estefanía Costa-Rama Henri Nouws Cristina Delerue-Matos Food spoilage is caused by the development of microorganisms, biogenic amines, and other harmful substances, which, when consumed, can lead to different health problems. Foodborne diseases can be avoided by assessing the safety...
Wed Sep 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 694: A Genotype-Phenotype Study of High-Resolution FMR1 Nucleic Acid and Protein Analyses in Fragile X Patients with Neurobehavioral Assessments Brain Sciences doi: 10.3390/brainsci10100694 Authors: Dejan B. Budimirovic Annette Schlageter Stela Filipovic-Sadic Dragana D. Protic Eran Bram E. Mark Mahone Kimberly Nicholson Kristen Culp Kamyab Javanmardi Jon Kemppainen Andrew Hadd Kevin Sharp Tatyana Adayev Giuseppe LaFauci...
Wed Sep 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 695: The Effect of Tactile Training on Sustained Attention in Young Adults Brain Sciences doi: 10.3390/brainsci10100695 Authors: Yu Luo Jicong Zhang Sustained attention is crucial for higher-order cognition and real-world activities. The idea that tactile training improves sustained attention is appealing and has clinical significance. The aim of this study was to explore whether tactile training could improve visual sustained attention. Using 128-channel...
Wed Sep 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 692: Genetic Variation and Autism: A Field Synopsis and Systematic Meta-Analysis Brain Sciences doi: 10.3390/brainsci10100692 Authors: Jinhee Lee Min Ji Son Chei Yun Son Gwang Hun Jeong Keum Hwa Lee Kwang Seob Lee Younhee Ko Jong Yeob Kim Jun Young Lee Joaquim Radua Michael Eisenhut Florence Gressier Ai Koyanagi Brendon Stubbs Marco Solmi Theodor B. Rais Andreas Kronbichler Elena Dragioti Daniel Fernando Pereira...
Wed Sep 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 691: Distinct Effects of Acute Aerobic Exercise on Declarative Memory and Procedural Memory Formation Brain Sciences doi: 10.3390/brainsci10100691 Authors: Xuru Wang Rui Zhu Chenglin Zhou Yifan Chen Objective: To investigate the different effects of acute aerobic exercise on the formation of long-term declarative memory (DM) and procedural memory (PM). Methods: Twenty-two young men completed DM and PM tasks under three experimental conditions:...
Wed Sep 30, 2020 03:00
Brain Sciences, Vol. 10, Pages 693: Effects of Subthalamic Nucleus Deep Brain Stimulation and Levodopa on Balance in People with Parkinson’s Disease: A Cross Sectional Study Brain Sciences doi: 10.3390/brainsci10100693 Authors: David S. May Linda R. van Dillen Gammon M. Earhart Kerri S. Rawson Joel S. Perlmutter Ryan P. Duncan Subthalamic nucleus deep brain stimulation (STN-DBS) and levodopa are common treatment strategies for Parkinson’s disease (PD). However,...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2834: Gene Panel Tumor Testing in Ovarian Cancer Patients Significantly Increases the Yield of Clinically Actionable Germline Variants beyond BRCA1/BRCA2 Cancers doi: 10.3390/cancers12102834 Authors: Ana Barbosa Pedro Pinto Ana Peixoto Joana Guerra Carla Pinto Catarina Santos Manuela Pinheiro Carla Escudeiro Carla Bartosch João Silva Manuel R. Teixeira Since the approval of PARP inhibitors for the treatment of high-grade serous ovarian...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2835: Understanding the Effects of Radiotherapy on the Tumour Immune Microenvironment to Identify Potential Prognostic and Predictive Biomarkers of Radiotherapy Response Cancers doi: 10.3390/cancers12102835 Authors: Shuhui Cheng Eleanor J. Cheadle Timothy M. Illidge Radiotherapy (RT) is a highly effective anti-cancer treatment. Immunotherapy using immune checkpoint blockade (ICI) has emerged as a new and robust pillar in cancer therapy; however, the response...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2828: Senescent Tumor CD8+ T Cells: Mechanisms of Induction and Challenges to Immunotherapy Cancers doi: 10.3390/cancers12102828 Authors: Wei Liu Paweł Stachura Haifeng C. Xu Sanil Bhatia Arndt Borkhardt Philipp A. Lang Aleksandra A. Pandyra The inability of tumor-infiltrating T lymphocytes to eradicate tumor cells within the tumor microenvironment (TME) is a major obstacle to successful immunotherapeutic treatments. Understanding the immunosuppressive...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2833: Biopathological Significance of PIWI–piRNA Pathway Deregulation in Invasive Breast Carcinomas Cancers doi: 10.3390/cancers12102833 Authors: Didier Meseure Sophie Vacher Sabah Boudjemaa Marick Laé André Nicolas Renaud Leclere Walid Chemlali Gabriel Champenois Anne Schnitzler Laetitia Lesage Thierry Dubois Ivan Bieche The PIWI proteins emerging in the development of human cancers, edify PIWI-piRNA ribonucleoproteic complexes...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2832: Transcriptome Profiling Reveals New Insights into the Immune Microenvironment and Upregulation of Novel Biomarkers in Metastatic Uveal Melanoma Cancers doi: 10.3390/cancers12102832 Authors: Yamini Krishna Amelia Acha-Sagredo Dorota Sabat-Pośpiech Natalie Kipling Kim Clarke Carlos R. Figueiredo Helen Kalirai Sarah E. Coupland Metastatic uveal melanoma (mUM) to the liver is incurable. Transcriptome profiling of 40 formalin-fixed paraffin-embedded...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2830: Fertility Preservation in Childhood Cancer: Endocrine Activity in Prepubertal Human Testis Xenografts Exposed to a Pubertal Hormone Environment Cancers doi: 10.3390/cancers12102830 Authors: Marsida Hutka Prashant Kadam Dorien Van Saen Natalie Z. M. Homer Jaime Onofre W. Hamish B. Wallace Lee B. Smith Jan-Bernd Stukenborg Ellen Goossens Rod T. Mitchell Survivors of childhood cancer are at risk for long-term treatment-induced health...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2831: Treatment Combinations with DNA Vaccines for the Treatment of Metastatic Castration-Resistant Prostate Cancer (mCRPC) Cancers doi: 10.3390/cancers12102831 Authors: Melissa Gamat-Huber Donghwan Jeon Laura E. Johnson Jena E. Moseman Anusha Muralidhar Hemanth K. Potluri Ichwaku Rastogi Ellen Wargowski Christopher D. Zahm Douglas G McNeel Metastatic castration-resistant prostate cancer (mCRPC) is a challenging disease to treat, with...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2819: The Warburg Effect 97 Years after Its Discovery Cancers doi: 10.3390/cancers12102819 Authors: Rosa Maria Pascale Diego Francesco Calvisi Maria Maddalena Simile Claudio Francesco Feo Francesco Feo The deregulation of the oxidative metabolism in cancer, as shown by the increased aerobic glycolysis and impaired oxidative phosphorylation (Warburg effect), is coordinated by genetic changes leading to the activation of oncogenes and the loss of oncosuppressor...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2826: The Additional Value of Ultrafast DCE-MRI to DWI-MRI and 18F-FDG-PET to Detect Occult Primary Head and Neck Squamous Cell Carcinoma Cancers doi: 10.3390/cancers12102826 Authors: Roland M. Martens Ruud van der Stappen Thomas Koopman Daniel P. Noij Emile F. Comans Gerben J. Zwezerijnen Marije R. Vergeer C. René Leemans Remco de Bree Ronald Boellaard Jonas A. Castelijns Pim de Graaf To evaluate diagnostic accuracy of qualitative...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2827: Impact of Intercurrent Introduction of Steroids on Clinical Outcomes in Advanced Non-Small-Cell Lung Cancer (NSCLC) Patients under Immune-Checkpoint Inhibitors (ICI) Cancers doi: 10.3390/cancers12102827 Authors: Andrea De Giglio Laura Mezquita Edouard Auclin Félix Blanc-Durand Mariona Riudavets Caroline Caramella Gala Martinez Jose Carlos Benitez Patricia Martín-Romano Lamiae El-Amarti Lizza Hendriks Roberto Ferrara Charles...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2824: Directed Evolution of Therapeutic Antibodies Targeting Glycosylation in Cancer Cancers doi: 10.3390/cancers12102824 Authors: Ron Amon Ronit Rosenfeld Shahar Perlmutter Oliver C. Grant Sharon Yehuda Aliza Borenstein-Katz Ron Alcalay Tal Marshanski Hai Yu Ron Diskin Robert J. Woods Xi Chen Vered Padler-Karavani Glycosylation patterns commonly change in cancer, resulting in expression of tumor-associated carbohydrate antigens...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2825: Extracellular Vesicles as Biomarkers in Cancer Immunotherapy Cancers doi: 10.3390/cancers12102825 Authors: Matthen Mathew Mariam Zade Nadia Mezghani Romil Patel Yu Wang Fatemeh Momen-Heravi Extracellular vesicles (EVs), including exosomes and microvesicles, are membrane-bound vesicles secreted by most cell types during both physiologic conditions as well in response to cellular stress. EVs play an important role in intercellular communication...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2820: Assessment of CAR T Cell Frequencies in Axicabtagene Ciloleucel and Tisagenlecleucel Patients Using Duplex Quantitative PCR Cancers doi: 10.3390/cancers12102820 Authors: Maria-Luisa Schubert Alexander Kunz Anita Schmitt Brigitte Neuber Lei Wang Angela Hückelhoven-Krauss Sascha Langner Birgit Michels Antje Wick Volker Daniel Carsten Müller-Tidow Peter Dreger Michael Schmitt Chimeric antigen receptor (CAR) T cell (CART)...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2823: Functional Transcription Factor Target Networks Illuminate Control of Epithelial Remodelling Cancers doi: 10.3390/cancers12102823 Authors: Ian M. Overton Andrew H. Sims Jeremy A. Owen Bret S. E. Heale Matthew J. Ford Alexander L. R. Lubbock Erola Pairo-Castineira Abdelkader Essafi Cell identity is governed by gene expression, regulated by transcription factor (TF) binding at cis-regulatory modules. Decoding the relationship between TF...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2822: Detection of EGFR Mutations Using Bronchial Washing-Derived Extracellular Vesicles in Patients with Non-Small-Cell Lung Carcinoma Cancers doi: 10.3390/cancers12102822 Authors: Juhee Park Chaeeun Lee Jung Seop Eom Mi-Hyun Kim Yoon-Kyoung Cho The detection of epidermal growth factor receptor (EGFR) mutation, based on tissue biopsy samples, provides a valuable guideline for the prognosis and precision medicine in patients with lung cancer. In this...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2821: Advanced Fusion Imaging and Contrast-Enhanced Imaging (CT/MRI–CEUS) in Oncology Cancers doi: 10.3390/cancers12102821 Authors: Vincent Schwarze Johannes Rübenthaler Constantin Marschner Matthias Philipp Fabritius Johannes Rueckel Nicola Fink Daniel Puhr-Westerheide Eva Gresser Matthias Frank Froelich Moritz Ludwig Schnitzer Nils Große Hokamp Saif Afat Michael Staehler Thomas Geyer Dirk-André Clevert Fusion imaging...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2829: XPO1E571K Mutation Modifies Exportin 1 Localisation and Interactome in B-cell Lymphoma Cancers doi: 10.3390/cancers12102829 Authors: Hadjer Miloudi Élodie Bohers François Guillonneau Antoine Taly Vincent Cabaud Gibouin Pierre-Julien Viailly Gaëtan Jego Luca Grumolato Fabrice Jardin Brigitte Sola The XPO1 gene encodes exportin 1 (XPO1) that controls the nuclear export of cargo proteins and RNAs. Almost 25% of primary mediastinal...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2814: Does Fungal Biliary Contamination after Preoperative Biliary Drainage Increase Postoperative Complications after Pancreaticoduodenectomy? Cancers doi: 10.3390/cancers12102814 Authors: Pauline Tortajada Alain Sauvanet Stephanie Truant Nicolas Regenet Régis Souche Stéphane Benoist Fabrice Muscari Jean Regimbeau Sebastien Gaujoux Antonio Cunha Lillian Schwarz FRENCH-ACHBT Working Group (1) Background: preoperative biliary drainage...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2817: Translating Biomarkers of Cholangiocarcinoma for Theranosis: A Systematic Review Cancers doi: 10.3390/cancers12102817 Authors: Imeshi Wijetunga Laura E. McVeigh Antonia Charalambous Agne Antanaviciute Ian M. Carr Amit Nair K. Raj Prasad Nicola Ingram P. Louise Coletta Cholangiocarcinoma (CCA) is a rare disease with poor outcomes and limited research efforts into novel treatment options. A systematic review of CCA biomarkers was undertaken...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2816: Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational Profiling Cancers doi: 10.3390/cancers12102816 Authors: Flávia L. C. Faldoni Rolando A. R. Villacis Luisa M. Canto Carlos E. Fonseca-Alves Sarah S. Cury Simon J. Larsen Mads M. Aagaard Cristiano P. Souza Cristovam Scapulatempo-Neto Cynthia A. B. T. Osório Jan Baumbach Fabio A. Marchi Silvia R. Rogatto Inflammatory breast cancer (IBC)...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2815: DUX Hunting—Clinical Features and Diagnostic Challenges Associated with DUX4-Rearranged Leukaemia Cancers doi: 10.3390/cancers12102815 Authors: Jacqueline A. Rehn Matthew J. O'Connor Deborah L. White David T. Yeung DUX4-rearrangement (DUX4r) is a recently discovered recurrent genomic lesion reported in 4–7% of childhood B cell acute lymphoblastic leukaemia (B-ALL) cases. This subtype has favourable outcomes, especially in children and...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2813: Radio-Resistance and DNA Repair in Pediatric Diffuse Midline Gliomas Cancers doi: 10.3390/cancers12102813 Authors: Henriette Pedersen Kjeld Schmiegelow Petra Hamerlik Malignant gliomas (MG) are among the most prevalent and lethal primary intrinsic brain tumors. Although radiotherapy (RT) is the most effective nonsurgical therapy, recurrence is universal. Dysregulated DNA damage response pathway (DDR) signaling, rampant genomic instability, and radio-resistance...
Wed Sep 30, 2020 03:00
Cancers, Vol. 12, Pages 2818: Identification and Clinical Application of Immunological Receptors Targeting Mutated Antigens Expressed by Solid Tumors Cancers doi: 10.3390/cancers12102818 Authors: Anna Pasetto In the recent years, immunotherapy has achieved impressive results utilizing different approaches, from (chimeric antigen receptor) CAR-T cells directed against CD19 for the treatment of leukemia and lymphomas to the Nobel prize-winning strategy of check-point inhibition for the...
Wed Sep 30, 2020 03:00
Cells, Vol. 9, Pages 2218: Short-Term Rapamycin Preconditioning Diminishes Therapeutic Efficacy of Human Adipose-Derived Stem Cells in a Murine Model of Multiple Sclerosis Cells doi: 10.3390/cells9102218 Authors: Rachel M. Wise Mark A. A. Harrison Brianne N. Sullivan Sara Al-Ghadban Sarah J. Aleman Amber T. Vinluan Emily R. Monaco Umberto M. Donato India A. Pursell Bruce A. Bunnell Human adipose-derived stem cells (ASCs) show immense promise for treating inflammatory...
Wed Sep 30, 2020 03:00
Cells, Vol. 9, Pages 2216: Molecular and Cellular Mechanisms of Human Astrocytoma Progression: Advances in Knowledge to Reach Therapeutic Horizons Cells doi: 10.3390/cells9102216 Authors: Sergio Comincini Human astrocytic tumors are primary central nervous system (CNS) tumors that arise either from astrocytes or from precursor cells. A growing number of epidemiological and incidence studies in different countries underlined that, in addition to increasing economic costs for health systems,...
Wed Sep 30, 2020 03:00
Cells, Vol. 9, Pages 2217: Combinatory Treatment of Canavanine and Arginine Deprivation Efficiently Targets Human Glioblastoma Cells via Pleiotropic Mechanisms Cells doi: 10.3390/cells9102217 Authors: Olena Karatsai Pavel Shliaha Ole N. Jensen Oleh Stasyk Maria Jolanta Rędowicz Glioblastomas are the most frequent and aggressive form of primary brain tumors with no efficient cure. However, they often exhibit specific metabolic shifts that include deficiency in the biosynthesis...
Wed Sep 30, 2020 03:00
Cells, Vol. 9, Pages 2214: Progressive Photoreceptor Dysfunction and Age-Related Macular Degeneration-Like Features in rp1l1 Mutant Zebrafish Cells doi: 10.3390/cells9102214 Authors: Nicole C. L. Noel Nathan J. Nadolski Jennifer C. Hocking Ian M. MacDonald W. Ted Allison Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Pathogenic mutations in RP1L1 lead to photoreceptor degenerations such as occult macular...
Wed Sep 30, 2020 03:00
Cells, Vol. 9, Pages 2215: Root Border Cells and Mucilage Secretions of Soybean, Glycine Max (Merr) L.: Characterization and Role in Interactions with the Oomycete Phytophthora Parasitica Cells doi: 10.3390/cells9102215 Authors: Marc Ropitaux Sophie Bernard Damien Schapman Marie-Laure Follet-Gueye Maïté Vicré Isabelle Boulogne Azeddine Driouich Root border cells (BCs) and their associated secretions form a protective structure termed the root extracellular trap (RET)...
Wed Sep 30, 2020 03:00
Climate, Vol. 8, Pages 108: Selection of Effective GCM Bias Correction Methods and Evaluation of Hydrological Response under Future Climate Scenarios Climate doi: 10.3390/cli8100108 Authors: Yaogeng Tan Sandra M. Guzman Zengchuan Dong Liang Tan Global climate change is presenting a variety of challenges to hydrology and water resources because it strongly affects the hydrologic cycle, runoff, and water supply and demand. In this study, we assessed the effects of climate change...
Wed Sep 30, 2020 03:00
Dentistry Journal, Vol. 8, Pages 109: Effect of an Er,Cr:YSGG Laser on the Surface of Implants: A Descriptive Comparative Study of 3 Different Tips and Pulse Energies Dentistry Journal doi: 10.3390/dj8040109 Authors: Ehsan Chegeni Antonio España-Tost Rui Figueiredo Eduard Valmaseda-Castellón Josep Arnabat-Domínguez Peri-implant diseases are one of the main complications of dental implants. There are no well-established guidelines regarding laser parameters for implant decontamination....
Wed Sep 30, 2020 03:00
Diagnostics, Vol. 10, Pages 777: Altered Regional Cerebral Blood Perfusion in Mild Cognitive Impairment Patients with Dizziness Diagnostics doi: 10.3390/diagnostics10100777 Authors: Seunghee Na Jooyeon Jamie Im Hyeonseok Jeong Eek-Sung Lee Tae-Kyeong Lee Yong-An Chung In-Uk Song Dizziness is a common symptom among the general population, especially in the elderly. Previous studies have reported that dizziness may be associated with various cognitive functions including...
Wed Sep 30, 2020 03:00
Diagnostics, Vol. 10, Pages 775: Peptide Nucleic Acid (PNA)-Enhanced Specificity of a Dual-Target Real-Time Quantitative Polymerase Chain Reaction (RT-qPCR) Assay for the Detection and Differentiation of SARS-CoV-2 from Related Viruses Diagnostics doi: 10.3390/diagnostics10100775 Authors: Won-Suk Choi Ju Hwan Jeong Halcyon Dawn G. Nicolas Sol Oh Khristine Joy C. Antigua Ji-Hyun Park Beomkyu Kim Sun-Woo Yoon Kyeong Seob Shin Young Ki Choi Yun Hee Baek Min-Suk...
Wed Sep 30, 2020 03:00
Diagnostics, Vol. 10, Pages 774: Potential Trends of Point-of-Care Diagnostics—The Next Generation of the Laboratory Diagnosis Diagnostics doi: 10.3390/diagnostics10100774 Authors: Sheng-Wen Lin Ching-Fen Shen Chao-Min Cheng With the current worldwide outbreak of COVID-19, developing rapid, effective, and convenient detection tools has become imperative [...]
Wed Sep 30, 2020 03:00
Diagnostics, Vol. 10, Pages 776: Clinical and Imaging Features of Primary Cardiac Angiosarcoma Diagnostics doi: 10.3390/diagnostics10100776 Authors: Yan Chen Yu Li Nan Zhang Jianfeng Shang Xiaodan Li Jiayi Liu Lei Xu Dongting Liu Zhonghua Sun Zhaoying Wen This study aims to explore computed tomography (CT) and magnetic resonance imaging (MRI) features of patients diagnosed with primary cardiac angiosarcoma. The study involved the analysis of 12 patients diagnosed...
Wed Sep 30, 2020 03:00
Diagnostics, Vol. 10, Pages 773: Automated Segmentation and Severity Analysis of Subdural Hematoma for Patients with Traumatic Brain Injuries Diagnostics doi: 10.3390/diagnostics10100773 Authors: Negar Farzaneh Craig A. Williamson Cheng Jiang Ashok Srinivasan Jayapalli R. Bapuraj Jonathan Gryak Kayvan Najarian S. M. Reza Soroushmehr Detection and severity assessment of subdural hematoma is a major step in the evaluation of traumatic brain injuries. This is a retrospective...
Wed Sep 30, 2020 03:00
Diagnostics, Vol. 10, Pages 772: Relationship between Semi-Quantitative Parameters of Thallium-201 Myocardial Perfusion Imaging and Coronary Artery Disease Diagnostics doi: 10.3390/diagnostics10100772 Authors: Chin-Chuan Chang Ming-Hui Yang Chih-Ting Liu Hsiu-Lan Chu Chia-Yang Lin Wei-Jheng Yen Chao-Yu Chung Sheng-Yow Ho Yu-Chang Tyan This study aimed to investigate the diagnostic performance of semi-quantitative parameters of thallium-201 myocardial perfusion...
Wed Sep 30, 2020 03:00
Diagnostics, Vol. 10, Pages 771: Endometriosis and the Urinary Tract: From Diagnosis to Surgical Treatment Diagnostics doi: 10.3390/diagnostics10100771 Authors: Mathew Leonardi Mercedes Espada Rosanne M. Kho Javier F. Magrina Anne-Elodie Millischer Luca Savelli George Condous We aim to describe the diagnosis and surgical management of urinary tract endometriosis (UTE). We detail current diagnostic tools, including advanced transvaginal ultrasound, magnetic resonance...
Wed Sep 30, 2020 03:00
Diversity, Vol. 12, Pages 378: Relationships between Foliar Fungal Endophyte Communities and Ecophysiological Traits of CAM and C3 Epiphytic Bromeliads in a Neotropical Rainforest Diversity doi: 10.3390/d12100378 Authors: Peter H. Tellez Carrie L. Woods Stephen Formel Sunshine A. Van Bael Vascular epiphytes contribute up to 35% of the plant diversity and foliar biomass of flowering plants. The family Bromeliaceae is a monophyletic group of plants native to the Neotropics. Epiphytic...
Wed Sep 30, 2020 03:00
Epigenomes, Vol. 4, Pages 23: UV Radiation and Its Relation to DNA Methylation in Epidermal Cells: A Review Epigenomes doi: 10.3390/epigenomes4040023 Authors: Naila Francis Paulo de de Oliveira Beatriz Fernandes de de Souza Marina de Castro de Castro Coêlho DNA methylation is the most studied epigenetic mark, and it can be altered by environmental factors. Among these factors, ultraviolet radiation (UV) is little explored within this context. While the relationship between UV radiation...
Wed Sep 30, 2020 03:00
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