Remdesivir-COVID-19: drug interactions in dentistry:
OBJECTIVE: Remdesivir is a nucleotide analogue prodrug that inhibits viral RNA polymerases. It has been recognized recently as a promising antiviral drug against a wide array of RNA viruses (including SARS/MERS-CoV5). We aimed at determining which drugs used in dentistry interact with Remdesivir in order to avoid adverse reactions that may worsen the condition of patients with COVID-19.
MATERIALS AND METHODS: A literature review was conducted to identify potential drug interactions between remdesivir (used in the treatment of COVID-19) and drugs prescribed in dentistry. The search was made in the databases PubMed and MEDLINE and official websites using key terms remdesivir, drug interactions and dentistry for articles published up to 31st July 2020.
RESULTS: According to the articles reviewed, a total of 279 drugs interact with Remdesivir. Two major interactions have been reported, 277 moderate drug interactions, and one with alcohol/food. The drug interactions involving drugs prescribed in dentistry are all moderate drug interactions and are (according to drug group): (1) antibiotics: azithromycin, clavulanate, doxycycline, erythromycin, levofloxacin; (2) antifungals: clotrimazole, fluconazole, itraconazole, ketoconazole; (3) non-steroidal anti-inflammatories (NAIDS): celecoxib diclofenac, etodolac, flurbiprofen, ibuprofen, ketoprofen, ketorolac, mefenamic acid, naproxen, piroxicam.
CONCLUSIONS: It is clinically necessary for oral health professionals to be aware of possible drug interactions that may occur between remdesivir and drugs commonly prescribed in dentistry in order to prevent adverse reactions that may even endanger the life of a patient with COVID-19.
L'articolo Remdesivir-COVID-19: drug interactions in dentistry sembra essere il primo su European Review.
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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- Polysomnographic Outcomes After Observation for Mi...
- Patent foramen ovale in various cerebrovascular di...
- Clinical FLASH Radiotherapy System: Pediatric Whol...
- Treatment of rheumatic immune-related adverse even...
- Triapine.
- Localized Extra-pulmonary Small Cell Carcinoma (EP...
- Obesity on voriconazole pharmacokinetics
- Investigate coagulation disturbance with viscoelas...
- Nodal recurrences after stereotactic body radiothe...
- Liquid biopsy for ALK-positive early non-small-cel...
- Immune checkpoint inhibitors in clinical diagnosis...
- Childhood Anaplastic Large Cell Lymphoma
- Injection laryngoplasty for treatment of congenita...
- TGF-β and Eomes control the homeostasis of CD8+ re...
- Cell Cycle
- Inhibition of Nuclear Pore Complex Formation Selec...
- Azidothymidine (AZT) Inhibits Proliferation of Hum...
- Protein Translation Inhibition is Involved in the ...
- Polyploid giant cancer cells (PGCC)
- Mutations in the stromal antigen 3 (STAG3) gene ca...
- Low C6orf141 Expression in Oral Cancer.
- Therapy change in metastatic renal cell carcinoma ...
- Cytokine Storm Syndromes..............familiar hem...
- Right cardiac involvement in lung disease
- Tracheopulmonary Complications of a Malpositioned ...
- Ultrasound-Guided Local Anesthetic Nerve Blocks in...
- Head and neck cancer patient-derived xenograft models
- TGF-β and Eomes control the homeostasis of CD8+ re...
- EUFOREA treatment algorithm for allergic rhinitis.
- STAT1 deficiency predisposes to spontaneous otitis...
- Identifying risk factors for the prognosis of head...
- Orbital Involvement by Biphenotypic Sinonasal Sarcoma
- Association between treatment package time and cli...
- Herpesvirus Epigenetic Reprogramming and Oncogenesis.
- Epidemiologic factors in patients with advanced he...
- Improved nutritional support with immune-modulatin...
- Genome-wide CRISPR screens of oral squamous cell c...
- Pros and Cons of the Exoscope for Otologic Surgery.
- Postoperative Oral Corticosteroids Improve Results...
- Intestinal flora in patients with chronic rhinosin...
- Clinical utility of Epstein-Barr virus DNA and oth...
- The synergy of germline C634Y and V292M RET mutati...
- Rapid recurrence in head and neck cancer
- Chromoendoscopy in the Workup of Patients with Hea...
- Preliminary experience with exoscope in lacrimal s...
- Comparison of transnasal and transoral routes of m...
- Analysis of vascular-associated factors and the pr...
- Functional CRISPR dissection of gene networks cont...
- FGF Expression in HPV16-positive and -negative SCC...
- Genomic Database Analysis for Head and Neck Cancer...
- Merkel cell carcinoma of the lower lip
- Free flap head and neck microsurgery with VITOMⓇ 3...
- Unexplained repeated pregnancy loss is associated ...
- Unexplained repeated pregnancy loss is associated ...
- Dexmedetomidine versus midazolam on cough and reco...
- Sialendoscopy in Chronic Obstructive Sialadenitis ...
- Pectoralis Major Onlay vs Interpositional Reconstr...
- Prevalence of Tinnitus in an Aging Population and ...
- Outcomes in Oropharyngeal Squamous Cell Carcinoma ...
- Human Pathogenic Variants of TBC1D24 Associated wi...
- Immune Escape Mechanisms and Their Clinical Releva...
- Targeting Liver Cancer Stem Cells: An Alternative ...
- Balance/Strengthening Exercises in Heart Failure.
- Epicutaneous immunotherapy protects cashew sensiti...
- PIPE‐cloned human IgE and IgG4 antibodies: New too...
- Effect of topical swallowed steroids on the bacter...
- Advances and novel developments in drug hypersensi...
- Timed barium swallow for assessing long‐term treat...
- Addition of small‐bowel transit scintigraphy to ga...
- Seated anorectal manometry during simulated evacua...
- Infectious Mononucleosis Causing Acute Liver Failure
- Pazopanib in Recurrent Metastatic Carotid Body Par...
- High-Grade Epstein-Barr Virus-Negative Biphenotypi...
- Hypercalcemia Associated with Extramammary Paget’s...
- Spinal Cord Stimulation for Treating Chronic Low B...
- Appendix muscle bands
- Inflammation, apoptosis and autophagy as critical ...
- Systemic lupus erythematosus (SLE) triggered by CO...
- MiR-181-5p protects from sepsis via repressing HMG...
- Vitamin deficiency as risk factor for SARS-CoV-2 i...
- Remdesivir-COVID-19: drug interactions in dentistry
- The therapeutic potential of targeting ACE2 in COV...
- Maternal and fetal outcomes of COVID-19, SARS, and...
- Toxins
- Veterinary Sciences
- Antibiotics
- Medicine by Alexandros G. SfakianakisMedicine by A...
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