First-line pemetrexed plus cisplatin followed by gefitinib maintenance therapy versus gefitinib monotherapy in East Asian never-smoker patients with locally advanced or metastatic nonsquamous non-small cell lung cancer: Quality of life results from a randomized phase 3 trial

In a randomized study of pemetrexed plus cisplatin followed by maintenance gefitinib (PC/G) or gefitinib monotherapy (G) in East Asian never-smoker patients with advanced nonsquamous non-small cell lung cancer, quality of life symptoms were more favorable in the G than PC/G group. In patients with wild-type epidermal growth factor receptor, tumor-related symptoms appeared to improve more with PC/G than G.

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