A Rare Case of Hydrocystoma of the Labial Commissure: Histopathology and Clinical Picture.

A Rare Case of Hydrocystoma of the Labial Commissure: Histopathology and Clinical Picture.

Photomed Laser Surg. 2017 Jan 24;:

Authors: Angiero F, Ferrante F, Crippa R, Ottonello A, Mauro S, Valente MG

Abstract
OBJECTIVE: Hydrocystomas (HCs) are rare, benign, skin adnexal cystic tumors that may be either eccrine or apocrine.
BACKGROUND DATA: Apocrine-HCs are cystic lesions that arise from the apocrine secretory coil, whereas eccrine-HCs are retention cysts of the eccrine duct. The commonest site is around the eyes, on the ears, scalp, chest, shoulders, or feet; HCs of the oral cavity are very rare.
METHODS: The case is reported of a 36 year-old man with a nodular lesion that was 7 × 5 mm in size on the labial commissure. The lesion was treated in direct contact with a diode laser that was 980 nm in continuous wave mode, with a 320 μm fiber at 1.8-2.0 W of power.
RESULTS: Complete healing occurred within 15 days. There were no adverse effects. The patient was carefully followed up, and there has been no recurrence. Histopathologically, the lesion was a multilocular cyst lined with a single-, and in some areas a double-layered epithelium with eosinophilic cytoplasm. Immunohistochemically, the secretory epithelium was positive for S-100 protein and negative for cytokeratin 5/6.
CONCLUSIONS: The histopathological and immunohistochemically diagnosis was of eccrine HC. The report stresses differential diagnosis versus cystic lesions of the labial commisure.

PMID: 28121520 [PubMed - as supplied by publisher]

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