IgE cross-linking impairs monocyte antiviral responses and inhibits influenza-driven Th1 differentiation

Publication date: Available online 10 January 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Regina K. Rowe, David M. Pyle, Andrew R. Tomlinson, Tinghong Lv, Zheng Hu, Michelle A. Gill

Teaser

Capsule Summary: IgE-mediated allergic activation impairs the virus-induced Th1 lymphocyte priming capacity of human monocytes in response to influenza exposure. These findings represent one potential mechanism contributing to the link between viral infections and allergic disease.


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