Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma.

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Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma.

Indian J Pathol Microbiol. 2016 Jul-Sep;59(3):410-2

Authors: Rabade N, Bibi A, Ghodke K, Patkar N, Tembhare P, Amare P, Subramanian PG, Gujral S

Abstract
Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.

PMID: 27510693 [PubMed - indexed for MEDLINE]

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