Biologic Therapy in the Treatment of Chronic Skin Disorders.

Related Articles

Biologic Therapy in the Treatment of Chronic Skin Disorders.

Immunol Allergy Clin North Am. 2017 May;37(2):315-327

Authors: Fernandez JM, Fernandez AP, Lang DM

Abstract
Understanding of the immunologic pathways involved in the pathogenesis of skin-related diseases is constantly advancing. Several biologic agents play important therapeutic roles for management of patients with chronic urticaria, atopic dermatitis, and psoriasis, particularly omalizumab for antihistamine-resistant chronic urticaria, interleukin (IL)-1 inhibitors for cryopyrin-associated periodic syndrome and Schnitzler syndrome, dupilumab for recalcitrant atopic dermatitis, and IL-17 inhibitors for psoriasis. The therapeutic utility of biologic agents for patients with immune-related dermatologic disorders is likely to expand in the future. This article reviews the data regarding biologic agents and their utility in the management of specific skin-related disorders.

PMID: 28366479 [PubMed - in process]

http://ift.tt/2oGMrHn