Biological Therapies of Immunologic Diseases: Strategies for Immunologic Interventions.

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Biological Therapies of Immunologic Diseases: Strategies for Immunologic Interventions.

Immunol Allergy Clin North Am. 2017 May;37(2):247-259

Authors: Polk BI, Rosenwasser LJ

Abstract
The immune system possesses a vast number of potential targets for therapeutic intervention. Although therapies for many pathways have been pursued, only few have yielded significant success. Hindrances in altering biologic pathways include the potential for unwanted downstream effects, ineffectiveness owing to biological redundancy, recognition of a therapeutic molecule as foreign by the body's innate immune system, and the risks of subsequent malignancy and/or autoimmunity. This article covers currently available biotherapeutic agent classes as well as potential direction for future therapy.

PMID: 28366475 [PubMed - in process]

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