Modification of apparent intracerebral hematoma volume on T2∗-weighted images during normobaric oxygen therapy may contribute to false diagnosis.

Modification of apparent intracerebral hematoma volume on T2∗-weighted images during normobaric oxygen therapy may contribute to false diagnosis.

J Clin Neurosci. 2018 Mar 20;:

Authors: Goulay R, Drieu A, Di Palma C, Pro-Sistiaga P, Delcroix N, Chazalviel L, Saulnier R, Gakuba C, Goursaud S, Young AR, Gauberti M, Orset C, Emery E, Vivien D, Gaberel T

Abstract
It was previously reported that normobaric oxygen therapy (NBO) significantly affected T2∗-weighted imaging in a mouse model of intracerebral hemorrhage (ICH). However, it is unclear whether a similar phenomenon exists in large volume ICH as seen in human pathology. We investigated the effects of NBO on T2∗-weighted images in a pig model of ICH. Our data show that NBO makes disappear a peripheral crown of the hematoma, which in turn decreases the apparent volume of ICH by 18%. We hypothesized that this result could be translated to ICH in human, and subsequently could lead to inaccurate diagnostic.

PMID: 29571939 [PubMed - as supplied by publisher]

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