Meat reintroduction in a patient with alpha-gal allergy

A 56-year-old woman presented to a drug allergy clinic for evaluation of a possible allergic reaction to acetaminophen. Two months before presentation the patient took 1000mg acetaminophen for pain relief and five hours later awoke with pruritic hives that resolved with diphenhydramine. Two weeks later, she took acetaminophen and developed pruritic hives four hours later, this time with vomiting, cramping, pruritic mouth, and sensation of throat closure. These symptoms resolved with diphenhydramine.

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