Source:Annals of Allergy, Asthma & Immunology
Author(s): Michael S. Blaiss, Eva Hammerby, Susan Robinson, Tessa Kennedy-Martin, Sarah Buchs
ObjectiveTo evaluate the literature regarding the burden of allergic rhinitis (AR) and allergic rhinoconjunctivitis (ARC) in adolescents (10-19 years).Data SourcesSearches were performed in MEDLINE, Embase, Health Technology Assessment Database, and National Health Service Economic Evaluation Database for studies evaluating concepts of symptoms, quality of life (QOL), daily activities, sleep, examination performance, school absenteeism and presenteeism, and treatment burden in adolescents with AR or ARC.Study SelectionsEnglish-language journal articles indexed in the last 15 years describing non-interventional population-based studies. Records were assessed by 2 independent reviewers.ResultsA total of 27 articles were identified; outcomes evaluated were: symptoms (n=6 studies), QOL (n=9), daily activities (n=5), emotional aspects (n=3), sleep (n=6), education (n=7), and treatment burden (n=2). AR symptoms rated most bothersome were rhinorrhea, nasal congestion, and itchy eyes. QOL was worse in adolescents with AR versus controls regardless of QOL instrument used. Nasal symptoms and nasal obstruction were more likely to be associated with poor QOL in adolescents than in adults or younger children, respectively. Daily functioning and sleep were also negatively impacted by AR. In addition, a detrimental effect on absenteeism, school productivity, and academic performance was reported.ConclusionAlthough AR and ARC are sometimes perceived as trivial conditions, this review indicates that their impact on adolescent life is negative and far-reaching. It is critical that clinicians gain a greater understanding of the unique burden of AR and ARC in adolescents to ensure they receive prompt and appropriate care and treatment in order to improve clinical and academic outcomes.
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