Spiritual care experiences by cancer patients, their family caregivers and healthcare team members in oncology practice settings: A qualitative study. Explore (NY). 2020 Aug 28;: Authors: Moosavi S, Rohani C, Borhani F, Akbari ME Abstract PURPOSE: Integrating spirituality into the patient care within a healthcare team, increases the ability to provide "holistic care" for cancer patients. The spiritual care experiences of different involved...
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Long-term Clinical Outcome of Trastuzumab and Lapatinib for HER2-positive Metastatic Colorectal Cancer. Clin Colorectal Cancer. 2020 Jun 27;: Authors: Tosi F, Sartore-Bianchi A, Lonardi S, Amatu A, Leone F, Ghezzi S, Martino C, Bencardino K, Bonazzina E, Bergamo F, Fenocchio E, Martinelli E, Troiani T, Siravegna G, Mauri G, Torri V, Marrapese G, Valtorta E, Cassingena A, Cappello G, Bonoldi E, Vanzulli A, Regge D, Ciardiello F, Zagonel V, Bardelli A, Trusolino...
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Urinary biomarkers in bladder cancer: A review of the current landscape and future directions. Urol Oncol. 2020 Sep 09;: Authors: Ng K, Stenzl A, Sharma A, Vasdev N Abstract AIM: This narrative review aims to describe established and emerging urinary biomarkers in the diagnosis and surveillance of non-muscle invasive bladder cancer. It provides a comprehensive account of classical, FDA-approved protein biomarkers and discusses their limitations....
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Use of symptom-focused oncological cancer therapies in hospices: a retrospective analysis. BMC Palliat Care. 2020 Sep 12;19(1):140 Authors: Kaiser U, Vehling-Kaiser U, Kück F, Mechie NC, Hoffmann A, Kaiser F Abstract BACKGROUND: There is controversy regarding the practical implementation of symptom-focused oncological cancer therapies to hospice residents. In this study, we aim to analyse the use and indication of supportive-oncological cancer...
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Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07514
Mon Sep 14, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c09331
Mon Sep 14, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c07274
Mon Sep 14, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02754
Mon Sep 14, 2020 07:00
Analytical ChemistryDOI: 10.1021/acs.analchem.0c03650
Mon Sep 14, 2020 07:00
Acoustic signaling by fishes has been recognized for millennia, but is typically regarded as comparatively rare within ray-finned fishes; as such, it has yet to be integrated into broader concepts of vertebrate evolution. We map the most comprehensive data set of volitional sound production of ray-finned fishes (Actinopterygii) yet assembled onto a family level phylogeny of the group, a clade representing more than half of extant vertebrate species. Our choice of family-level rather than species-level...
Mon Sep 14, 2020 03:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01468K, PaperMengya Lv, Yanhao Zhang, Jiayi Fan, Yanyun Yang, Sheng Chen, Gaolin Liang, Shusheng ZhangDeveloping suitable molecular tools for monitoring SO2 and its derivatives in living organisms is attractive due to their importance for human health. Herein, the first near-infrared fluorescent probe Mito-HN with...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01326A, PaperHyobeen Lee, Dong-Min Kim, Dong-Eun KimSince influenza occurs globally every year, it is important to develop a facile and accurate method to detect the influenza virus. This study aimed to develop a sensitive fluorometric assay...The content of this RSS Feed (c) The Royal Society of Chemistry
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A Commentary on "Impact of Hyperglycemia on Neuronal Apoptosis after Subarachnoid Hemorrhage in Rodent Brain: An Experimental Research" (International Journal of Surgery, 2020. Ephu ahead of Print). Int J Surg. 2020 Sep 10;: Authors: Arnaout MM PMID: 32920192 [PubMed - as supplied by publisher]
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An Invited Commentary on "Acute Care Surgery during the COVID-19 pandemic in Spain: Changes in volume, causes and complications. A multicentre retrospective cohort study". Int J Surg. 2020 Sep 10;: Authors: Rege SA, Bandekar P PMID: 32920191 [PubMed - as supplied by publisher]
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An Invited Commentary on "Comparison of the Learning Curves for Robotic Left and Right Hemihepatectomy: A Retrospective Cohort Study" (International Journal of Surgery 2020; Epub adhead of Print). Int J Surg. 2020 Sep 10;: Authors: Karimian F PMID: 32920190 [PubMed - as supplied by publisher]
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Ethnicity and COVID-19 - A commentary on "World Health Organization declares global emergency: A review of the 2019 novel coronavirus (COVID-19)" (Int J Surg 2020;76:71-6). Int J Surg. 2020 Sep 10;: Authors: Dey TJ, Sinha A PMID: 32920189 [PubMed - as supplied by publisher]
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An Invited Commentary on: "Comparison of the Learning Curves for Robotic Left and Right Hemiheparectomy: A Prospective Cohort Study". (International Journal of Surgery 2020; 81:19-25. Int J Surg. 2020 Sep 10;: Authors: Alikhanov R PMID: 32920188 [PubMed - as supplied by publisher]
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An invited commentary on: "Robotic pancreaticoduodenectomy in elderly and young patients: a retrospective cohort study" (International Journal of Surgery 2020; 81:61-65). Int J Surg. 2020 Sep 10;: Authors: Berrevoet F PMID: 32920187 [PubMed - as supplied by publisher]
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An invited commentary on: "A Randomized Controlled Trial on Irrigation of Open Appendectomy Wound with Gentamicin-Saline Solution versus Saline Solution for Prevention of Surgical Site Infection" (International Journal of Surgery 2020; Epub ahead of Print). Int J Surg. 2020 Sep 10;: Authors: Akay S, Akay H PMID: 32920186 [PubMed - as supplied by publisher]
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A Commentary on "Impact of the Coronavirus (COVID-19) pandemic on surgical practice - Part 1" (International Surgery 2020; 79:168-179) The Effectiveness of Telemedicine during the COVID-19 Pandemic. Int J Surg. 2020 Sep 10;: Authors: Mustafa H, Alradhawi M, Al-Hussein M, Dewji A PMID: 32920185 [PubMed - as supplied by publisher]
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An Invited Commentary on "Robotic pancreaticoduodenectomy in elderly and younger patients: A Retrospective Cohort Study" (International Journal Surgery 2020 Epub ahead of Print). Int J Surg. 2020 Sep 10;: Authors: Calik B, Atici SD PMID: 32920184 [PubMed - as supplied by publisher]
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An Invited commentary on: "One Anastomosis/Mini Gastric Bypass (OAGB-MGB) as Revisional Bariatric Surgery after failed Primary Adjustable Gastric Band (LAGB) and Sleeve Gastrectomy (SG): A Systematic Review of 1075 patients" (International Journal of Surgery 2020;81:32-38). Int J Surg. 2020 Sep 10;: Authors: Abo-Ryia MH PMID: 32920183 [PubMed - as supplied by publisher]
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"Innocent" arytenoid adduction asymmetry: An etiological survey. Eur Arch Otorhinolaryngol. 2020 Sep 12;: Authors: Mathew AS, Menon JR Abstract PURPOSE: To estimate the incidence of "innocent" arytenoid adduction asymmetry (AAA) among patients presenting at a laryngology clinic, identify its association with demographic characteristics, symptomatology and various clinical/pathological conditions and thereby determine its clinical significance....
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Abstract Objectives The aim of this study was to evaluate the relationship between personality traits and perceived treatment success in oral lichen planus. Material and methods A total of 53 patients with diagnosed oral lichen planus were evaluated at the time of diagnosis and along the course of their treatment. The visual analogue scale (VAS) was used...
Mon Sep 14, 2020 03:00
The fibrillin microfibril/ elastic fiber network: A critical extracellular supramolecular: scaffold to balance skin homeostasis. Exp Dermatol. 2020 Sep 13;: Authors: Adamo CS, Zuk AV, Sengle G Abstract Supramolecular networks composed of fibrillins (fibrillin-1 and -2) and associated ligands form intricate cellular microenvironments which balance skin homeostasis and direct remodeling. Fibrillins assemble into microfibrils which are not only...
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The Whole Body as the System in Systems Immunology. iScience. 2020 Aug 28;23(9):101509 Authors: Poon MML, Farber DL Abstract The human immune system is comprised of a diverse and interactive network of specialized cells localized in diverse tissues throughout the body, where they mediate protection against pathogens and environmental insults while maintaining tissue homeostasis. Although much of our understanding of human immunology has derived...
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Association of plasma YKL-40 with brain amyloid-β levels, memory performance, and sex in subjective memory complainers. Neurobiol Aging. 2020 Aug 17;96:22-32 Authors: Vergallo A, Lista S, Lemercier P, Chiesa PA, Zetterberg H, Blennow K, Potier MC, Habert MO, Baldacci F, Cavedo E, Caraci F, Dubois B, Hampel H, INSIGHT-preAD study group and the Alzheimer Precision Medicine Initiative (APMI), INSIGHT-preAD study group, Alzheimer Precision Medicine Initiative (APMI)...
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Impact of milk thistle (Silybum marianum) on the mycotoxin caused redox-homeostasis imbalance of ducks liver. Toxicon. 2020 Sep 10;: Authors: Anna E, Krisztina S, Klára S, Anna B, Erzsébet F, Krisztina H, Hedvig F Abstract The Fusarium mycotoxins deoxynivalenol (DON) and zearalenone (ZEA) frequently contaminate grain crops, especially maize, the basis of poultry's feed. Mycotoxins enter the food chain and induce pathological changes in edible...
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[Long-term occupational situation after cancer: A French registry-based study]. Bull Cancer. 2020 Sep 09;: Authors: Saim A, Gernier F, Licaj I, Rod J, Velten M, Klein D, Mercier M, Joly F Abstract INTRODUCTION: Few studies have explored the long-term occupational situation after cancer. The aim of our study were to study the employment status among long-term cancer survivors and to compare it to cancer-free controls from the general population...
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Chronic hepatitis and HIV risks amongst Pakistani migrant men in a French suburb and insights into health promotion interventions: the ANRS Musafir qualitative study. BMC Public Health. 2020 Sep 12;20(1):1393 Authors: Cailhol J, Khan N Abstract BACKGROUND: Seine-Saint-Denis is a deprived departement (French administrative unit) in the North-East of Paris, France, hosting the majority of South Asian migrants in France. In recent years, the number...
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Which interventions increase hearing protection behaviors during noisy recreational activities? A systematic review. BMC Public Health. 2020 Sep 13;20(1):1376 Authors: Loughran MT, Lyons S, Plack CJ, Armitage CJ Abstract BACKGROUND: Hearing loss and tinnitus are global concerns that can be reduced through hearing protection behaviors (e.g., earplug use). Little is known about the effectiveness of interventions to increase hearing protection...
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Synthesis, chemical and biochemical characterization of Lu2O3-iPSMA nanoparticles activated by neutron irradiation. Mater Sci Eng C Mater Biol Appl. 2020 Dec;117:111335 Authors: Ancira-Cortez A, Ferro-Flores G, Jiménez-Mancilla N, Morales-Avila E, Trujillo-Benítez D, Ocampo-García B, Santos-Cuevas C, Escudero-Castellanos A, Luna-Gutiérrez M Abstract Among the nanomaterials, rare sesquioxides (lanthanide oxides such as Lu2O3) are of interest...
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Background. Degradation of the extracellular matrix (ECM), an essential step in tumour invasion and metastasis, is mainly dependent on the activities of both matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs). This study aimed to explore whether expression of MMP-7 and TIMP-1 alone and in combination can be used as a prognostic marker for gastric cancer (GC). Method. A total of 285 patients who had undergone tumourectomy for GC were included. Gastric tumour tissues...
Mon Sep 14, 2020 17:35
Efficacy of argon-helium cryoablation andits effects on immune function of patients with neck malignant tumors. Clin Otolaryngol. 2020 Sep 13;: Authors: Zheng Z, Zhao Y, An Y, Li N, Bo C, Ma W, Guo Y, Zou C, Tian B, Zhang S Abstract OBJECTIVES: Our study aimedto investigate the clinical efficacy of argon-helium cryoablation and its effects on the immune function of patients with neck malignant tumors. DESIGN: Retrospective study. ...
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Randomized Clinical Trial on Reduction of Radiotherapy Dose to the Elective Neck in Head and Neck Squamous Cell Carcinoma: Results on the Quality of Life. Qual Life Res. 2020 Sep 13;: Authors: Deschuymer S, Nevens D, Duprez F, Daisne JF, Voordeckers M, De Neve W, Nuyts S Abstract PURPOSE: A randomized trial was initiated to investigate whether a reduction of the dose to the elective nodal sites would result in less toxicity and improvement...
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Myosin light chain kinase is a potential target for hypopharyngeal cancer treatment. Biomed Pharmacother. 2020 Sep 10;131:110665 Authors: Cao F, Zhu L, Zhang J, Pongkorpsakol P, Kuo WT, Turner JR, Zhou Q, Wang Y, Chen F, Liu Y, Zuo L Abstract Hypopharyngeal cancer is squamous cell carcinoma (SCC) with the worst prognosis among the head and neck cancers. Overall, the 5-year survival rate remains poor although diagnostic imaging, radiation, chemotherapy,...
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lncRNA SNHG8 promotes aggressive behaviors of nasopharyngeal carcinoma via regulating miR-656-3p/SATB1 axis. Biomed Pharmacother. 2020 Sep 10;131:110564 Authors: Tian X, Liu Y, Wang Z, Wu S Abstract BACKGROUND: Long non-coding RNA (lncRNA) has been proposed to regulate tumorigenesis, however, the role of small nucleolar RNA host gene 8 (SNHG8) in nasopharyngeal carcinoma (NPC) remains unclear. METHODS: Levels of SNHG8 in NPC tissues...
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Incorporation of telemedicine by rhinologists: The COVID-19 pandemic and beyond. Am J Otolaryngol. 2020 Jun 02;41(6):102567 Authors: Svider PF, Setzen M, Ow R, Folbe AJ, Eloy JA, Johnson AP Abstract OBJECTIVES: The current analysis queries rhinologists' attitudes about the use of telemedicine, including the degree to which it has impacted practice patterns during the COVID-19 pandemic. Our objective was to survey rhinologists and understand...
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Voice change after thyroidectomy without vocal cord paralysis: Analysis of 2,297 thyroidectomy patients. Surgery. 2020 Sep 09;: Authors: Kim SY, Kim GJ, Lee DH, Bae JS, Lee SH, Kim JS, Hwang YS, Shim MR, Park YH, Sun DI Abstract BACKGROUND: Some patients experience long-term voice change after thyroidectomy. One of the most common symptoms of voice change is pitch lowering, which is closely related to unfavorable voice quality. Here we observed...
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Assessing Patient and Caregiver Interest for a Head and Neck Cancer Educational Mobile Application. J Med Imaging Radiat Sci. 2020 Sep;51(3S):S9-S10 Authors: Bozzelli C, Kang J, So N, Rosewall T, Cashell A PMID: 32919747 [PubMed - as supplied by publisher]
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Does Current Patient Education Prepare Head and Neck Patients for Life Post-Radiotherapy Treatment: A Needs Assessment Study. J Med Imaging Radiat Sci. 2020 Sep;51(3S):S15 Authors: Singh A, McGuffin M, Bola R PMID: 32919722 [PubMed - as supplied by publisher]
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Evaluation of the Role of Optical Surface Monitoring Systems in Aiding Pre-CBCT Setups for Head and Neck and Neurological Cancer Patients. J Med Imaging Radiat Sci. 2020 Sep;51(3S):S13-S14 Authors: DiPietro S, VanSantvoort T, Ostapiak O PMID: 32919716 [PubMed - as supplied by publisher]
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LaryngorhinootologieDOI: 10.1055/a-1253-8392 Hintergrund Die Kupplungsvorrichtung für mikrovaskuläre Anastomosen hat in der freien Gewebetransplantation weite Verbreitung gefunden. Ziel der Arbeit ist der Vergleich der Thromboserate und des Transplantatversagens in Abhängigkeit von der Anastomosentechnik an einem großen Kopf-Hals-Tumorzentrum. Material und Methoden Retrospektive Auswertung von allen Patienten, die im Zeitraum von 2001–2019 eine freie Lappenrekonstruktion erhalten...
Mon Sep 14, 2020 02:00
Interplay between HMGA and TP53 in cell cycle control along tumor progression. Cell Mol Life Sci. 2020 Sep 12;: Authors: Meireles Da Costa N, Palumbo A, De Martino M, Fusco A, Ribeiro Pinto LF, Nasciutti LE Abstract The high mobility group A (HMGA) proteins are found to be aberrantly expressed in several tumors. Studies (in vitro and in vivo) have shown that HMGA protein overexpression has a causative role in carcinogenesis process. HMGA proteins...
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Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements. iScience. 2020 Sep 01;23(9):101518 Authors: Chen D, Chen QY, Wang Z, Zhu Y, Kluz T, Tan W, Li J, Wu F, Fang L, Zhang X, He R, Shen S, Sun H, Zang C, Jin C, Costa M Abstract Replication-dependent canonical histone messenger RNAs (mRNAs) do not terminate with a poly(A) tail at the 3' end. We previously demonstrated that exposure...
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Drug-like biimidazole derivatives dually target c-MYC/BCL-2 G-quadruplexes and inhibit acute myeloid leukemia. Bioorg Chem. 2020 Sep 03;104:104264 Authors: Hu MH, Yu BY, Wang X, Jin G Abstract Chemotherapy is the main approach for treating acute myeloid leukemia (AML). However, this therapy can cause severe side effects as well as drug resistance, hence calling for new therapeutic strategies. As c-MYC and BCL-2 are often overexpressed in AML,...
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Design and synthesis of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as antiproliferative EGFR and BRAFV600E dual inhibitors. Bioorg Chem. 2020 Sep 03;104:104260 Authors: Al-Wahaibi LH, Gouda AM, Abou-Ghadir OF, Salem OIA, Ali AT, Farghaly HS, Abdelrahman MH, Trembleau L, Abdu-Allah HHM, Youssif BGM Abstract Recent studies have shown additive and synergistic effects associated with the combination of kinase inhibitors. BRAFV600E...
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Design and synthesis of some barbituric and 1,3-dimethylbarbituric acid derivatives: A non-classical scaffold for potential PARP1 inhibitors. Bioorg Chem. 2020 Aug 28;104:104198 Authors: Eldin A Osman E, Hanafy NS, George RF, El-Moghazy SM Abstract Six series based on barbituric acid 5a-e, 10a-d; thiobarbituric acid 6a-e, 11a-d and 1,3-dimethylbarbituric acid 7a-e, 12a-d were prepared and screened for their in vitro PARP1 inhibition. They revealed...
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Garcinone C suppresses colon tumorigenesis through the Gli1-dependent hedgehog signaling pathway. Phytomedicine. 2020 Sep 03;79:153334 Authors: Chen J, Qiu S, Kim JT, Cho JS, Moon JH, Zhou Y, Auh JH, Lee HJ Abstract BACKGROUND: Although garcinone C, a natural xanthone derivative identified in the pericarp of Garcinia mangostana, has been demonstrated to exert different health beneficial activities in oxidative stress and β-amyloid aggregation,...
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Orally available tubulin inhibitor VERU-111 enhances antitumor efficacy in paclitaxel-resistant lung cancer. Cancer Lett. 2020 Sep 10;: Authors: Mahmud F, Deng S, Chen H, Miller DD, Li W Abstract Lung cancer is the most common cause of cancer associated mortality. Chemotherapeutic agents, such as paclitaxel, are important treatment options but drug resistance often develops upon prolonged use. We report here the preclinical evaluation of a...
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Streptococcus thermophilus inhibits colorectal tumorigenesis through secreting β-galactosidase. Gastroenterology. 2020 Sep 10;: Authors: Li Q, Hu W, Liu WX, Zhao LY, Huang D, Liu XD, Chan H, Zhang Y, Zeng JD, Coker OO, Kang W, Man Ng SS, Zhang L, Wong SH, Gin T, Vai Chan MT, Wu JL, Yu J, Kei Wu WK Abstract BACKGROUND & AIMS: Streptococcus thermophilus was identified to be depleted in patients with colorectal cancer (CRC) by shotgun metagenomic...
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Zusammenfassung Ziel der Arbeit In dieser Studie wurden die funktionellen Ergebnisse nach transmandibulärer Resektion und Rekonstruktion mittels mikrovaskulär anastomosiertem Radialistransplantat (TMR+Tx) gegenüber einer primären Radiochemotherapie (pRCT) bei fortgeschrittenen orophayngealen Plattenepithelkarzinomen (OPSCC) verglichen. Methoden Es erfolgte...
Mon Sep 14, 2020 03:00
Zusammenfassung Hintergrund Die Corona-Krise beeinflusst nicht nur das professionelle Handeln, sondern auch die Lehre an den Universitäten. Schlagworte wie „E-Learning“ und „Digitalisierung“ suggerieren die Möglichkeit innovativer, ad hoc verfügbarer Lösungsansätze für die Lehre in der aktuellen COVID-19-Situation. Die aktuelle Umstellung auf digitale Lehre ist aber nicht primär durch eine didaktische Sinnhaftigkeit oder institutionelle...
Mon Sep 14, 2020 03:00
Zusammenfassung Hintergrund Speicheldrüsenkarzinome („salivary gland carcinomas“, SGC) sind seltene Tumoren, die aufgrund ihrer histologischen Vielfalt und den in Abhängigkeit vom Subtyp unterschiedlichen Krankheitsverläufen eine Herausforderung für Diagnostik und Therapie darstellen. Über die Zusammensetzung des Tumormikromilieus (TME) bei SGC ist bislang wenig bekannt. Ein umfassenderes Verständnis der relevanten molekularen Veränderungen...
Mon Sep 14, 2020 03:00
Zusammenfassung Tumoren im Bereich des Oropharynx können zu schweren Funktionsstörungen führen. Diese werden zumeist durch die operative Therapie und/oder Radiotherapie verstärkt. Dabei sind der Schweregrad und die Art der Funktionsstörung abhängig vom Resektionsausmaß und ihrer Lokalisation. Komplette Organentfernungen führen generell zu einer stärkeren Beeinträchtigung als Teilresektionen. Aber auch Teilresektionen können ab einer bestimmten Größe zu nachhaltigen Störungen der...
Mon Sep 14, 2020 03:00
Zusammenfassung Hintergrund Die Epistaxis ist ein häufiges Symptom in der Arztpraxis und assoziiert mit verschiedenen Komorbiditäten und Medikamenten, insbesondere Antikoagulanzien. Trotz ihrer Alltäglichkeit gibt es nur wenige Daten zur Häufigkeit ihres Auftretens und möglichen Risikofaktoren. Methoden Die Studie untersuchte anhand einer großen Patientenpopulation...
Mon Sep 14, 2020 03:00
The management of giant neurofibroma is a challenge for clinical surgeons. Abundant malformed vessels exist in the tumor, and life-threatening hemorrhage can occur during operation. Moreover, repairing huge defects after radical resection is challenging. Hence, subtotal resection and debulking are more frequently performed than total resection. Although subtotal resection or debulking may reduce morbidity, it inevitably leads to a high rate of recurrence. In addition, subtotal resection or debulking...
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Introduction Significant variation exists in microsurgery training resources provided across plastic surgery residency programs, and dedicated microsurgery courses can be logistically difficult to access (cost, location, protected time, etc). Widespread use of personal digital technology has facilitated the emergence of resources that enable easily accessible microsurgical training through digital modalities that augment traditional training. The authors sought to conduct the first systematic...
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Background There is currently no consensus on the ideal plane for implant placement in breast reconstruction. The study compares the clinical efficacy and safety between prepectoral and subpectoral implant-based breast reconstruction. Methods PubMed, Web of Sciences, EMBASE, and Cochrane databases were systematically searched following the PRISMA guidelines. Inclusion criteria were articles describing implant-based breast reconstructions with implant placed either prepectorally or subpectorally....
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Background Plastic surgery residency programs in Israel have undergone several changes over the years, but the perspectives and satisfaction of the residents have not been investigated. Methods An anonymous national survey of plastic surgery residents in Israel was performed. Demographic, professional, and education variables were summarized using descriptive statistics, and findings were related to self-reported satisfaction levels using univariate analysis. Results The response rate...
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Background Spontaneous recovery of elbow flexion in obstetric brachial plexus palsy at 4 to 6 months of age is sufficient to exclude the child from the early microsurgical intervention. However, lack of complete active external rotation of shoulder is a common finding in such cases despite ongoing other arm and shoulder functions. Nerve transfer is proposed to manage such cases before the age of 18 months. Aim The aim of this study was to study the distal transfer of the spinal accessory...
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Background Whether patient driven or surgeon driven, social media can serve as a strong marketing tool to attract plastic surgery patients. At many training programs, chief residents have the opportunity to run an independent clinic, in which patients are evaluated for aesthetic and reconstructive procedures. In this study, the authors sought to investigate the downstream effect of a single positive review on a major social review site on cosmetic surgery volume. Methods A retrospective pre-post...
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Background Indications for adjuvant radiation therapy (XRT) in breast cancer have expanded. Although highly effective, XRT damages surrounding tissues and vasculature, often resulting in delayed or compromised breast reconstruction. Thus, effective yet safe methods of radiation injury prophylaxis would be desirable. Amifostine is a Food and Drug Administration–approved radioprotectant; however, concerns about its potential to also protect cancer remain. The purpose of this study was to evaluate...
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Nontuberculous Mycobacteria Infection After Autologous Fat Grafting for Cosmetic Breast Augmentation
Background Autologous fat grafting has been widely applied in cosmetic breast augmentation in recent years. However, nontuberculous mycobacteria infection, as one of the multiple complications described in the literature, has been less well discussed. Objective The aims of the study were to report 5 cases of nontuberculous mycobacteria infection after autologous fat injection for the cosmetic breast augmentation and to explore its causes. Methods In this noncomparative, retrospective,...
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No abstract available
02:44
Introduction Therapeutic mammaplasty is a well-established advanced oncoplastic technique for larger tumors in large breasts. However, the larger the breasts are, the greater is the lower outer parenchymal displacement due to weight resulting in relative emptiness in the medial/cleavage part. Therefore, the default practice of excising the medial wing parenchymal component of Wise pattern (WP) incision may either maintain or worsen such anatomy. Methods We present a technical innovation to...
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Background Increased operative volume has been associated with benefits in patient outcomes for a variety of surgical procedures. In autologous abdominally based breast reconstruction, however, there are few studies assessing the association between procedure volume and patient outcomes. The objectives of this study are to evaluate the associations between abdominal-based free flap breast reconstruction and patient outcomes. Methods The 2013–2014 Healthcare Cost and Utilization Project National...
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Introduction The traditional extended latissimus dorsi flap technique, in addition to lipofilling, has been one of the main procedures used for breast reconstruction after mastectomy. However, to obtain excellent results, this technique requires a large muscle harvest and further lipofilling sessions. The lipofilled mini dorsi flap technique, performed in a single operation, appealed to us as a way to improve the traditional technique. We present our experience with the lipofilled mini dorsi...
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Objective This study aimed to determine the benefits of sclerotherapy with OK-432 for the treatment of postoperative chronic lymphocele. Background Postoperative chronic lymphocele formation is common and accounts for a high postoperative morbidity. Nonsurgical strategies comprise repetitive percutaneous fluid aspiration or percutaneous sclerotherapy. OK-432 has been used to treat congenital lymphatic malformations with several reports of promising results. We hypothesized that it is more...
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Background Carbon monoxide is a gas produced by the combustion of hydrocarbon products that binds to heme molecules, 240 times more than oxygen, producing carboxyhemoglobin (COHb). As a result of its high affinity, there is shift of the oxyhemoglobin dissociation curve, compromising oxygen transport and delivery to tissues. Our study aim was to evaluate COHb elevation on admission as a predictor of worse outcomes in burn patients. Methods This is a 10-year retrospective review of the American...
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Background Rectus femoris necrosis is a rare but severe complication after anterolateral thigh flap (ALTF) harvesting. It has been previously reported that the blood supply of the rectus femoris (RF) often arises from the same source artery as the ALTF; however, precise descriptions of the relationship remain limited. This article revisits the blood supply of the RF based on computed tomography angiography (CTA) and analyzes the possible influence of the blood supply on the RF during ALTF harvesting. ...
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Proprioception is thought to be essential for normal joint homeostasis, and its decreased function has been associated with an increased risk of joint diseases. However, only a few studies have been performed on the association between proprioceptive function in the trapeziometacarpal joint (TMCJ) and osteoarthritis. The purpose of this study was to compare TMCJ proprioceptive function in elderly women with radiographic TMCJ osteoarthritis relative to age-matched control women without osteoarthritis....
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Purpose This study aimed to investigate the repair of bone defects in rabbits with tissue-engineered bones using cocultured endothelial progenitor cells (EPCs) and bone marrow mesenchymal stem cells (BMSCs) as seeding cells. Methods Endothelial progenitor cells and BMSCs were isolated and purified from the peripheral blood and bone marrow, respectively, of New Zealand rabbits. The third passage of BMSCs was cultured alone or with EPCs. Cells were characterized using specific markers and then...
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Background Interest in the treatment of mandibular condyle fracture in cases of maxillofacial trauma has been a huge concern for decades because of a diversity of opinions on the topic and the relatively few studies conducted on individuals treated by physiotherapy or rehabilitation with or without intermaxillary fixation (IMF). Methods We measured fracture gaps between bone ends over an 8-year period from 2012 to 2019. The study cohort was composed of only conservatively treated patients....
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Background Patients with hormone receptor-positive breast tumors receive hormonal therapy with either selective estrogen receptor modulators (SERMs) (eg, tamoxifen) or aromatase inhibitors (AIs) (eg, anastrozole) for 5 to 10 years. Patients are using these therapies frequently during breast reconstruction. Literature investigating the effects of hormonal modulators on breast reconstruction outcomes demonstrates conflicting results. We sought to perform a systematic evaluation to assess the effects...
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The existence of the “July effect,” or the idea that the new academic year intrinsically has an increased complication rate is evaluated in microsurgical free tissue transfer procedures. The National Surgical Quality Improvement Program registry was queried for all free flap procedures performed between 2005 and 2016 (n = 3405). Cases were grouped as having occurred in the first academic quarter (Q1: July 1–September 30) or fourth quarter (Q4: April 1–June 30). Demographical data and complications...
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No abstract available
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Horm Metab ResDOI: 10.1055/a-1260-4769© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
Mon Sep 14, 2020 02:00
Horm Metab ResDOI: 10.1055/a-1239-4349In 2016, the World Health Organization estimated that more than 1.9 billion adults were overweight or obese. This impressive number shows that weight excess is pandemic. Overweight and obesity are closely associated with a high risk of comorbidities, such as insulin resistance and its most important outcomes, including metabolic syndrome, type 2 diabetes mellitus, and cardiovascular...
Mon Sep 14, 2020 02:00
Isolated fallopian tube torsion associated with hydrosalpinx is a rare condition in the pediatric population. We present this unusual clinical case study in a sexually inactive girl.
Mon Sep 14, 2020 03:00
Endometriosis of the appendix is very uncommon, accounting for only about 1% of all cases of endometriosis. However, endometriosis is found in the appendix in approximately 8–13% of patients with deep infiltra...
Mon Sep 14, 2020 03:00
Background. Persistent peripheral CD4+T cell differentiation towards T helper (Th)2 rather than Th1 has been proved to be related to immunosuppression and poor prognosis in sepsis. However, it is unclear whether these circulating Th1 and Th2 subtype accumulations differed in septic populations of distinct infection sites and presented different associations with outcomes among patients with pulmonary versus nonpulmonary sepsis. Methods. From a secondary analysis of a prospective observational study,...
Mon Sep 14, 2020 14:20
Colistin is considered as one of the last-resort antibiotics and reliable antimicrobial susceptibility testing is therefore crucial. The reference standard for AST according to EUCAST and CLSI is broth microdi...
Mon Sep 14, 2020 03:00
The benefits of muscle in open lower limb fractures remains to be determined. This study compared statistically equivalent groups of open tibial fractures treated by free anterolateral thigh (ALT) flaps or ALT flaps incorporating muscle (ALT-Vastus Lateralis).Method and Results: Chang Gung Memorial Hospital, Taiwan, 2004-2008, 49 free flaps in open lower limb fractures (38 open tibial) were specifically reconstructed with free ALT or ALT-VL flaps.Risk factors for non-union: equivalent between the...
Mon Sep 14, 2020 03:00
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