Dual-emissive ratiometric fluorescent probe based on Eu3+/C-dots@MOF hybrids for the biomarker diaminotoluene sensing

Publication date: 1 November 2018
Source:Sensors and Actuators B: Chemical, Volume 272
Author(s): Si-Jia Qin, Bing Yan
A novel ratiometric fluorescence hybrid probe Eu³⁺/C-dots@MIL-53 (1a) has been synthesized by encapsulating the luminescent carbon dots and lanthanide ions Eu³⁺ into the metal-organic framework to yield the dual-emitting composite. The as-prepared fluorescent probe exhibited excellent optical properties and water-tolerance, with the potential to serve as a chemical sensor. Furthermore, the as-prepared fluorescent probe is a promising dual functional sensor with high selectivity and sensitivity for the detection and recognition of diaminotoluene (TDA), a metabolite of toluene diisocyanates (TDI) that has been associated with an increased risk of occupational asthma. Herein, we developed a sensitive, selective, and non-destructive method for early diagnosis of occupational asthma through the detection of exposure biomarker of TDI. The ratio of (IC-dots/IEu) ascended with the increased TDA concentrations. Thus, the reported TDA sensing system may be a potential candidate for further development of occupational diagnostic tool.

Graphical abstract

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