Evaluation of association between degree of background parenchymal enhancement on MRI and breast cancer subtype

Publication date: September–October 2018
Source:Clinical Imaging, Volume 51
Author(s): Richard Ha, Victoria Mango, Rend Al-Khalili, Eralda Mema, Lauren Friedlander, Elise Desperito, Ralph T. Wynn
PurposeEvaluate possible association between BPE and breast cancer tumor type/prognostic markers.MethodsIRB approved retrospective study from 1/2010–1/2014 identified 328 patients who had breast MRI and available clinical/pathology data. BPE was categorized according to BI-RADS. The association between BPE and breast cancer molecular subtype/prognostic factors was evaluated.ResultsNo significant association was present between high BPE and the following: HER2+ tumors, basal tumors, tumors with axillary nodal disease, high nuclear grade tumors, high Ki-67 index tumors or larger tumors.ConclusionPatients with high BPE may be at increased risk for breast cancer but not necessarily for those cancer subtypes with a poor prognosis.



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