Safety and Efficacy of Nanosecond Pulsed Electric Field Treatment of Seborrheic Keratoses: BACKGROUND
Nanosecond pulsed electric field technology (also known as Nano-Pulse Stimulation or NPS) is a nonthermal, drug-free, energy-based technology that has demonstrated effects on cellular structures of the dermis and epidermis in previous clinical studies.
OBJECTIVE
To evaluate the safety and efficacy of a single NPS treatment for clearing seborrheic keratoses (SKs).
MATERIALS AND METHODS
This study was a prospective, randomized, open-label, multisite, nonsignificant risk trial in which each subject served as their own control. Fifty-eight subjects had 3 of 4 confirmed SK lesions treated, resulting in 174 total treated lesions. Subjects returned for 5 to 6 follow-up evaluations and photographs.
RESULTS
At 106 days after NPS treatment, 82% of treated seborrheic keratoses were rated clear or mostly clear by the assessing physician. Seventy-one percent of lesions were rated clear or mostly clear by the 3 independent reviewers based on the 106-day photographs. All treated subjects returned for all study visits, and 78% of the subjects were satisfied or mostly satisfied with the outcome of the treatment. No adverse events were reported.
CONCLUSION
The NPS procedure was well tolerated and effective in the removal of SKs.
Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com
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- Benign cyst with xanthogranulomatous inflammation ...
- Extended right posterior liver sectionectomy for H...
- Emergency surgery for acute cholecystitis associat...
- inoperable or recurrent HER2-positive breast cance...
- Serum cystatin C: A potential predictor for hospit...
- Management Strategies of Ocular Chemical Burns: Cu...
- A Real-World Study of Dexamethasone Implant in Tre...
- Collagen-Supplemented Incubation Rapidly Augments ...
- The effect of vitamin D supplementation on surviva...
- Cytotoxic CD8+ T cells in cancer and cancer immuno...
- Autophagy as a therapeutic target in pancreatic ca...
- Can Straw Phonation Be Considered As Vocal Warm Up...
- Extraarticular extrasynovial solitary osteochondro...
- Neural Correlates of Sleep Recovery following Mela...
- Subjects with temporomandibular joint disc displac...
- defective endocytosis and proximal tubule dysfunct...
- Uncaria tomentosa reduces osteoclastic bone loss
- Intestinal resection affects whole-body arginine s...
- Understanding the mechanisms of placebo and nocebo...
- Prognostic Factors, Treatment, and Survival in Pri...
- Use of Autologous, Noncultured Melanocyte–Keratino...
- Guidance for the Management of Patients with Vascu...
- Strip Graft of the Eyebrow for the Treatment of Tr...
- A Large Defect on the Cheek
- Robust Single-Stage Reconstruction of the Mid and ...
- Vulvar Lichen Sclerosus: Consider Treatment With H...
- Temporary Greater Auricular Nerve Paresthesia Afte...
- Electron Microscopy of Argyria Treated With Picose...
- The Perialar Crescentic Advancement Flap: A Workho...
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- High- Versus Low-Density Fractional Laser in the T...
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- The Force Required to Inject a Column of Filler Th...
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