Pancreatic endometrial cyst mimics mucinous cystic neoplasm of the pancreas.

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Pancreatic endometrial cyst mimics mucinous cystic neoplasm of the pancreas.

World J Gastroenterol. 2017 Feb 14;23(6):1113-1118

Authors: Mederos MA, Villafañe N, Dhingra S, Farinas C, McElhany A, Fisher WE, Van Buren Ii G

Abstract
Pancreatic cysts include a variety of benign, premalignant, and malignant lesions. Endometrial cysts in the pancreas are exceedingly rare lesions that are difficult to diagnose pre-operatively. This report describes the findings in a 43-year-old patient with a recent episode of acute pancreatitis who presented with a large cyst in the tail of the pancreas. Imaging demonstrated a loculated pancreatic cyst, and cyst fluid aspiration revealed an elevated amylase and carcinoembryonic antigen. The patient experienced an interval worsening of abdominal pain, fatigue, diarrhea, and a 15-pound weight loss 3 mo after the initial episode of pancreatitis. With concern for a possible pre-malignant lesion, the patient underwent a laparoscopic distal pancreatectomy with splenectomy, which revealed a 16 cm × 12 cm × 4 cm lesion. Final histopathology was consistent with an intra-pancreatic endometrial cyst. Here we discuss the overlapping imaging and laboratory features of pancreatic endometrial cysts and mucinous cystic neoplasms of the pancreas.

PMID: 28246486 [PubMed - in process]

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