Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Τετάρτη 2 Σεπτεμβρίου 2020

 


Increased Burden of Rare Sequence Variants in GnRH-Associated Genes in Women with Hypothalamic Amenorrhea.
Related Articles Increased Burden of Rare Sequence Variants in GnRH-Associated Genes in Women with Hypothalamic Amenorrhea. J Clin Endocrinol Metab. 2020 Sep 01;: Authors: Delaney A, Burkholder AB, Lavender CA, Plummer L, Mericq V, Merino PM, Quinton R, Lewis KL, Meader BN, Albano A, Shaw ND, Welt CK, Martin KA, Seminara SB, Biesecker LG, Bailey-Wilson JE, Hall JE Abstract CONTEXT: Functional hypothalamic amenorrhea (HA) is a common, acquired...
American Goiter Association
Wed Sep 02, 2020 13:00
Body composition and bone mineral density in craniopharyngioma patients: a longitudinal study over 10 years.
Related Articles Body composition and bone mineral density in craniopharyngioma patients: a longitudinal study over 10 years. J Clin Endocrinol Metab. 2020 Sep 01;: Authors: van Santen SS, Olsson DS, Hammarstrand C, Wijnen M, Fiocco M, van den Heuvel-Eibrink MM, Johannsson G, Janssen JAMJL, van der Lely AJ, Neggers SJCMM Abstract CONTEXT: Patients with craniopharyngioma suffer from obesity and impaired bone health. Little is known about longitudinal...
American Goiter Association
Wed Sep 02, 2020 13:00
First trimester DEX-treatment is not associated with altered brain activity during working memory performance in adults.
Related Articles First trimester DEX-treatment is not associated with altered brain activity during working memory performance in adults. J Clin Endocrinol Metab. 2020 Sep 01;: Authors: Van't Westeinde A, Zimmermann M, Messina V, Karlsson L, Padilla N, Lajic S Abstract CONTEXT: Prenatal dexamethasone treatment (DEX) is sometimes used in pregnancies at risk for CAH to prevent virilisation in female foetuses with CAH. In boys and in foetuses not...
American Goiter Association
Wed Sep 02, 2020 13:00
Race, Ancestry and Vitamin D Metabolism: The Multi-Ethnic Study of Atherosclerosis.
Related Articles Race, Ancestry and Vitamin D Metabolism: The Multi-Ethnic Study of Atherosclerosis. J Clin Endocrinol Metab. 2020 Sep 01;: Authors: Hsu S, Hoofnagle AN, Gupta DK, Gutierrez OM, Peralta CA, Shea S, Allen NB, Burke G, Michos ED, Ix JH, Siscovick D, Psaty BM, Watson KE, Kestenbaum B, de Boer IH, Robinson-Cohen C Abstract CONTEXT: A comprehensive characterization of racial/ethnic variations in vitamin D metabolism markers may improve...
American Goiter Association
Wed Sep 02, 2020 13:00
Auditory representation of learned sound sequences in motor regions of the macaque brain.
Related Articles Auditory representation of learned sound sequences in motor regions of the macaque brain. Proc Natl Acad Sci U S A. 2020 06 30;117(26):15242-15252 Authors: Archakov D, DeWitt I, Kuśmierek P, Ortiz-Rios M, Cameron D, Cui D, Morin EL, VanMeter JW, Sams M, Jääskeläinen IP, Rauschecker JP Abstract Human speech production requires the ability to couple motor actions with their auditory consequences. Nonhuman primates might not...
cortical auditory
Wed Sep 02, 2020 16:22
Effect of Electrical Stimulation on the Treatment of Dysphonia: A Systematic Review.
Related Articles Effect of Electrical Stimulation on the Treatment of Dysphonia: A Systematic Review. J Voice. 2020 Aug 28;: Authors: Almeida ANS, Cunha DAD, Ferreira SLS, Guimarães BTL, Balata PMM, Silva HJD Abstract OBJECTIVES: The aim of this study was to review systematically the literature and to investigate the effects of electrical stimulation in treating dysphonia. STUDY DESIGN: This is a systematic review. METHODS:...
Dysphonia
Wed Sep 02, 2020 16:18
Breaking Down Silos: Collaboration in Head and Neck Reconstruction Research.
Related Articles Breaking Down Silos: Collaboration in Head and Neck Reconstruction Research. J Reconstr Microsurg. 2020 Sep 01;: Authors: Silva AK, Rodriguez ED, Jacobson AS, Levine JP Abstract BACKGROUND:  Collaboration has been shown to be beneficial when we have complex problems and highly specialized groups, such as in head and neck reconstruction. Otolaryngology, plastic surgery, and oral maxillofacial surgeons perform head and neck...
Head and Neck
Wed Sep 02, 2020 14:53
The Ideal Microsurgery Fellowship: A Survey of Fellows and Fellowship Directors.
Related Articles The Ideal Microsurgery Fellowship: A Survey of Fellows and Fellowship Directors. J Reconstr Microsurg. 2020 Sep 01;: Authors: Reghunathan M, Zaldana-Flynn M, Rose J, Crisera CA, Reid CM Abstract BACKGROUND:  Although microsurgery fellowships have existed since the 1980s, there is no established curriculum. Microsurgery fellowships vary greatly in clinical caseload, case diversity, and training resources, and there is no...
Head and Neck
Wed Sep 02, 2020 14:53
The Role of Cadaver-Based Flap Course in Microsurgical Education and Practice Patterns of Attendees: A Survey Study.
Related Articles The Role of Cadaver-Based Flap Course in Microsurgical Education and Practice Patterns of Attendees: A Survey Study. J Reconstr Microsurg. 2020 Sep 01;: Authors: Azoury SC, Othman S, Colen DL, Broach RB, Lin I, Zenn MR, Kovach SJ, Levin LS Abstract BACKGROUND:  In 2017, our institution initiated a cadaver laboratory-based course dedicated to teaching reconstructive microsurgery indications, preoperative planning, and flap...
Head and Neck
Wed Sep 02, 2020 14:53
Comparing autologous versus allogenic rib grafting in pediatric cleft rhinoplasty.
Related Articles Comparing autologous versus allogenic rib grafting in pediatric cleft rhinoplasty. Int J Pediatr Otorhinolaryngol. 2020 Aug 22;138:110264 Authors: Insalaco LF, Karp E, Zavala H, Chinnadurai S, Tibesar R, Roby BB Abstract BACKGROUND: Patients with cleft lip with or without cleft palate suffer from varying degrees of nasal deformity, often requiring nasal reconstruction to provide improved form and function. Rib cartilage...
Head and Neck
Wed Sep 02, 2020 14:53
Clinical application of a gantry-attachable plastic scintillating plate dosimetry system in pencil beam scanning proton therapy beam monitoring.
Related Articles Clinical application of a gantry-attachable plastic scintillating plate dosimetry system in pencil beam scanning proton therapy beam monitoring. Phys Med. 2020 Aug 29;77:181-186 Authors: Jeong S, Yoon M, Chung K, Ahn SH, Lee B, Seo J Abstract PURPOSE: The entrance beam fluence of therapeutic proton scanning beams can be monitored using a gantry-attachable plastic scintillating plate (GAPSP). This study evaluated the clinical...
Head and Neck
Wed Sep 02, 2020 14:53
HPVomics: An integrated resource for the human papillomavirus epitome and therapeutics.
Related Articles HPVomics: An integrated resource for the human papillomavirus epitome and therapeutics. Genomics. 2020 Aug 29;: Authors: Gupta AK, Kumar M Abstract Human papillomaviruses (HPVs) belongs to the Papillomaviridae family, which is divided into high-risk (HR), and low-risk (LR) HPVs based on their disease-causing competence. HR-HPVs 16 and 18 are known to cause distinct carcinomas like cervical and head and neck, whereas LR-HPVs...
Head and Neck
Wed Sep 02, 2020 14:53
Pharmacologic and surgical therapies for patients with Meniere's disease: A systematic review and network meta-analysis.
Related Articles Pharmacologic and surgical therapies for patients with Meniere's disease: A systematic review and network meta-analysis. PLoS One. 2020;15(9):e0237523 Authors: Ahmadzai N, Cheng W, Kilty S, Esmaeilisaraji L, Wolfe D, Bonaparte J, Schramm D, Fitzpatrick E, Lin V, Skidmore B, Hutton B Abstract BACKGROUND: Meniere's disease (MD) is a chronic condition of the inner ear consisting of symptoms that include vertigo attacks, fluctuating...
Head and Neck
Wed Sep 02, 2020 13:25
Otolaryngology Residency Interviews in a Socially Distanced World: Strategies to Recruit and Assess Applicants.
Related Articles Otolaryngology Residency Interviews in a Socially Distanced World: Strategies to Recruit and Assess Applicants. Otolaryngol Head Neck Surg. 2020 Sep 01;:194599820957961 Authors: Chou DW, Pletcher SD, Bruss D, Sung CK, Diaz RC, Liang J, Durr ML Abstract Due to concerns surrounding travel during the COVID-19 pandemic, the 2020-2021 otolaryngology residency application cycle will be conducted virtually for the first time....
Head and Neck
Wed Sep 02, 2020 13:25
Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor-beta expression in chronic rhinosinusitis with nasal polyps.
Related Articles Increased lipopolysaccharide content is positively correlated with glucocorticoid receptor-beta expression in chronic rhinosinusitis with nasal polyps. Immun Inflamm Dis. 2020 Sep 01;: Authors: Wang SB, Chen SM, Zhu KS, Zhou B, Chen L, Zou XY Abstract INTRODUCTION: Chronic rhinosinusitis with nasal polyps (CRSwNP) is a common and frequently occurring disease of the upper respiratory tract. The nasal instillation of the...
Head and Neck
Wed Sep 02, 2020 13:25
Efficacy of Chinese Medicine Acupoint Application Combined with Montelukast on Children with Perennial Allergic Rhinitis: A Randomized Controlled Trial.
Related Articles Efficacy of Chinese Medicine Acupoint Application Combined with Montelukast on Children with Perennial Allergic Rhinitis: A Randomized Controlled Trial. Chin J Integr Med. 2020 Sep 01;: Authors: Li YJ, Zong M, Ding LF, Rui XQ, Ma BY, Qin LP Abstract OBJECTIVE: To evaluate the efficacy of Chinese medicine acupoint application (CMAA) combined with Western medicine for perennial allergic rhinitis (PAR) in children. ...
Head and Neck
Wed Sep 02, 2020 13:25
Screening for irradiation vasculopathy by intima-media thickness sonography in head and neck cancer patients.
Related Articles Screening for irradiation vasculopathy by intima-media thickness sonography in head and neck cancer patients. Eur Arch Otorhinolaryngol. 2020 Sep 01;: Authors: Strüder D, Hellwig S, Rennau H, van Bonn S, Schraven SP, Mlynski R, Hildebrandt G, Schuldt T Abstract PURPOSE: Post-irradiation vasculopathy is a severe form of atherosclerosis and affects the prognosis of head and neck cancer survivors. Sonographic intima-media...
Head and Neck
Wed Sep 02, 2020 13:25
Association between blood transfusions and complications in head and neck reconstruction: a systematic review and meta-analysis.
Related Articles Association between blood transfusions and complications in head and neck reconstruction: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2020 Sep 01;: Authors: Giovacchini F, Bensi C, Paradiso D, Docimo R, Tullio A Abstract PURPOSE: The aim of this meta-analysis is to assess the correlation between blood transfusions and the medical/surgical complications after head and neck reconstructive surgery. ...
Head and Neck
Wed Sep 02, 2020 13:25
A Nordic survey of the management of palliative care in patients with head and neck cancer.
Related Articles A Nordic survey of the management of palliative care in patients with head and neck cancer. Eur Arch Otorhinolaryngol. 2020 Sep 01;: Authors: Boëthius H, Saarto T, Laurell G, Farnebo L, Mäkitie AA Abstract BACKGROUND: The five Nordic countries with a population of 27M people form a rather homogenous region in terms of health care. The management of Head and Neck Cancer (HNC) is centralized to the 21 university hospitals...
Head and Neck
Wed Sep 02, 2020 13:25
Recruitment and Networking With Social Media for the Otolaryngology Match in the COVID-19 Pandemic.
Related Articles Recruitment and Networking With Social Media for the Otolaryngology Match in the COVID-19 Pandemic. Otolaryngol Head Neck Surg. 2020 Sep 01;:194599820957952 Authors: Mecham JC, Menapace DC, Bowe SN, Carlson ML Abstract COVID-19 has created new challenges and opportunities regarding the way in which programs and applicants will interact in the 2020-2021 otolaryngology residency match cycle. Social media and other virtual...
Head and Neck
Wed Sep 02, 2020 13:25
Tracheotomy in a High-Volume Center During the COVID-19 Pandemic: Evaluating the Surgeon's Risk.
Related Articles Tracheotomy in a High-Volume Center During the COVID-19 Pandemic: Evaluating the Surgeon's Risk. Otolaryngol Head Neck Surg. 2020 Sep 01;:194599820955174 Authors: Thal AG, Schiff BA, Ahmed Y, Cao A, Mo A, Mehta V, Smith RV, Cohen HW, Ow TJ Abstract OBJECTIVE: Performing tracheotomy in patients with COVID-19 carries a risk of transmission to the surgical team due to potential viral particle aerosolization. Few studies have...
Head and Neck
Wed Sep 02, 2020 13:25
Disparities in Mortality from Larynx Cancer: Implications for Reducing Racial Differences.
Related Articles Disparities in Mortality from Larynx Cancer: Implications for Reducing Racial Differences. Laryngoscope. 2020 Sep 01;: Authors: Chen S, Dee EC, Muralidhar V, Nguyen PL, Amin MR, Givi B Abstract OBJECTIVE: Race predicts overall mortality (OM) of laryngeal squamous cell carcinoma (LSCC) in the United States (US). We assessed whether racial disparities affect cancer-specific mortality (CSM) using the Surveillance, Epidemiology,...
Head and Neck
Wed Sep 02, 2020 13:25
Personalized Medicine for allergy treatment: allergen immunotherapy still a unique and unmatched model.
Related Articles Personalized Medicine for allergy treatment: allergen immunotherapy still a unique and unmatched model. Allergy. 2020 Sep 01;: Authors: Incorvaia C, Al-Ahmad M, Ansotegui I, Arasi S, Bachert C, Bos C, Bousquet J, Bozek A, Caimmi D, Calderón M, Casale T, Custovic A, De Blay F, Demoly P, Devillier P, Didier A, Fiocchi A, Fox A, Gevaert P, Gomez M, Heffler E, Ilina N, Irani C, Jutel M, Karagiannis E, Klimek L, Kuna P, O'Hehir R, Kurbacheva O,...
Head and Neck
Wed Sep 02, 2020 13:25
Identification of genes associated with cancer stem cell characteristics in head and neck squamous cell carcinoma.
Related Articles Identification of genes associated with cancer stem cell characteristics in head and neck squamous cell carcinoma. Head Neck. 2020 Sep 01;: Authors: Huang GJ, Yang BB PMID: 32869879 [PubMed - as supplied by publisher]
Head and Neck
Wed Sep 02, 2020 13:25
Reply to Letter to the Editor regarding "Identification of genes associated with cancer stem cell characteristics in head and neck squamous cell carcinoma through co-expression network analysis".
Related Articles Reply to Letter to the Editor regarding "Identification of genes associated with cancer stem cell characteristics in head and neck squamous cell carcinoma through co-expression network analysis". Head Neck. 2020 Sep 01;: Authors: Zhu X PMID: 32869869 [PubMed - as supplied by publisher]
Head and Neck
Wed Sep 02, 2020 13:25
Inferior Meatus Mucosal Flap for Septal Reconstruction and Resurfacing After Nasoseptal Flap Harvest.
Related Articles Inferior Meatus Mucosal Flap for Septal Reconstruction and Resurfacing After Nasoseptal Flap Harvest. Laryngoscope. 2020 Sep 01;: Authors: Ruffner R, Pereira MC, Patel V, Peris-Celda M, Pinheiro-Neto CD PMID: 32869861 [PubMed - as supplied by publisher]
Head and Neck
Wed Sep 02, 2020 13:25
Efficacy and long-term follow-up of positional therapy by vibrotactile neck-based device in the management of positional OSA.
Related Articles Efficacy and long-term follow-up of positional therapy by vibrotactile neck-based device in the management of positional OSA. J Clin Sleep Med. 2020 Jul 06;: Authors: De Corso E, Mastrapasqua RF, Fiorita A, Settimi S, Mele DA, Picciotti PM, Loperfido A, Marrone S, Rizzotto G, Paludetti G, Scarano E Abstract STUDY OBJECTIVES: Different therapeutic strategies have been investigated for the treatment of positional-OSA (POSA),...
Head and Neck
Wed Sep 02, 2020 13:25
Comparison of primary musicality development between children with cochlear implants and children with normal hearing.
Related Articles Comparison of primary musicality development between children with cochlear implants and children with normal hearing. Acta Otolaryngol. 2020 Sep;140(9):749-755 Authors: Wang M, Xu T, Zhong Y, Zheng Y, Lv J, Luo J, Meng C, Guo Q, Gong S, Chen X Abstract Background: It is beneficial for CI patients listen to music. However it is necessary to take steps to improve the musicality of CI patients.Objectives: The aims of the...
Head and Neck
Wed Sep 02, 2020 13:25
Histoecology: Applying Ecological Principles and Approaches to Describe and Predict Tumor Ecosystem Dynamics Across Space and Time.
Related Articles Histoecology: Applying Ecological Principles and Approaches to Describe and Predict Tumor Ecosystem Dynamics Across Space and Time. Cancer Control. 2020 Jul-Aug;27(3):1073274820946804 Authors: Gatenbee CD, Minor ES, Slebos RJC, Chung CH, Anderson ARA Abstract Cancer cells exist within a complex spatially structured ecosystem composed of resources and different cell types. As the selective pressures imposed by this environment...
Head and Neck
Wed Sep 02, 2020 13:25
[Analysis of the divergent meridians of twelve meridians].
Related Articles [Analysis of the divergent meridians of twelve meridians]. Zhongguo Zhen Jiu. 2020 Aug 12;40(8):887-90 Authors: Gao B, Cheng Y, Zeng YL, Niu SP, Li YM, Wang Y Abstract This paper analyzes the problems existing in the current theory of divergent meridian ("Jingbie"), such as the unclear route of divergent meridian, the controversy in the "li-he-chu-ru" and the lack of in-depth research on the theory of "liuhe", clarifies...
Head and Neck
Wed Sep 02, 2020 13:25
HPV genotype is prognosticator for recurrence of respiratory papillomatosis in children.
Related Articles HPV genotype is prognosticator for recurrence of respiratory papillomatosis in children. Clin Otolaryngol. 2020 Aug 31;: Authors: Nogueira RL, Küpper DS, do Bonfim CM, Aragon DC, Damico TA, Miura CS, Passos IM, Nogueira ML, Rahal P, Valera FCP Abstract OBJECTIVES: This study aimed to compare the prognosis according to age, genotype or HPV variant in patients with recurrent respiratory papillomatosis (RRP). DESIGN:...
Head and Neck
Wed Sep 02, 2020 13:25
Otorhinolaryngology litigation in England: 727 clinical negligence cases against the NHS.
Related Articles Otorhinolaryngology litigation in England: 727 clinical negligence cases against the NHS. Clin Otolaryngol. 2020 Aug 31;: Authors: Navaratnam AV, Hariri A, Ho C, Machin J, Briggs T, Marshall A Abstract INTRODUCTION: Litigation against the National Health Service (NHS) in England is rising, costing £2.4 billion in 2018/19. The aim of this study was to determine the incidence and characteristics of otorhinolaryngology clinical...
Head and Neck
Wed Sep 02, 2020 13:25
Linking hyperosmotic stress and apoptotic sensitivity.
Related Articles Linking hyperosmotic stress and apoptotic sensitivity. FEBS J. 2020 Aug 31;: Authors: Stöhr D, Rehm M Abstract Cellular responses to hypertonic stress and how these are linked to the induction of or sensitisation to cell death signals are incompletely understood and rarely studied in cancer. Using cell lines derived from head and neck squamous cell carcinoma (HNSCC), Heimer et al. demonstrate that hypertonic environments...
Head and Neck
Wed Sep 02, 2020 13:25
Pathognomonic ultrasonic images of congenital pyriform sinus fistula in Children.
Related Articles Pathognomonic ultrasonic images of congenital pyriform sinus fistula in Children. Clin Otolaryngol. 2020 Aug 31;: Authors: Lin CY, Hsiao TY, Hsu WC Abstract Head and neck ultrasound can be used as a non-invasive image modality for the diagnosis of congenital pyriform sinus fistula (CPSF) in children. The pathognomonic ultrasonic images of CPSFs include a hypoechoic fistulous tract by the perithyroid or trans-thyroid route,...
Head and Neck
Wed Sep 02, 2020 13:25
An optimal acquisition and post-processing pipeline for hybrid IVIM-DKI in head and neck.
Related Articles An optimal acquisition and post-processing pipeline for hybrid IVIM-DKI in head and neck. Magn Reson Med. 2020 Aug 31;: Authors: Sijtsema ND, Petit SF, Poot DHJ, Verduijn GM, van der Lugt A, Hoogeman MS, Hernandez-Tamames JA Abstract PURPOSE: To optimize the diffusion-weighting b values and postprocessing pipeline for hybrid intravoxel incoherent motion diffusion kurtosis imaging in the head and neck region. METHODS:...
Head and Neck
Wed Sep 02, 2020 13:25
Mesenchymal Stem Cell Therapy for Osteoradionecrosis of the Mandible: a Systematic Review of Preclinical and Human Studies.
Related Articles Mesenchymal Stem Cell Therapy for Osteoradionecrosis of the Mandible: a Systematic Review of Preclinical and Human Studies. Stem Cell Rev Rep. 2020 Sep 01;: Authors: Gundestrup AK, Lynggaard CD, Forner L, Heino TJ, Jakobsen KK, Fischer-Nielsen A, Grønhøj C, von Buchwald C Abstract BACKGROUND: Osteoradionecrosis (ORN) of the mandible is a severe complication of radiotherapy for head and neck cancer and is arduously difficult...
Head and Neck
Wed Sep 02, 2020 13:25
Squamous cell cancer of the temporal bone: a review of the literature.
Related Articles Squamous cell cancer of the temporal bone: a review of the literature. Eur Arch Otorhinolaryngol. 2020 Aug 31;: Authors: Lechner M, Sutton L, Murkin C, Masterson L, O'Flynn P, Wareing MJ, Tatla T, Saeed S Abstract BACKGROUND AND AIMS: Squamous cell carcinoma (SCC) of the temporal bone is a rare malignancy accounting for only 0.2% of head and neck cancers. There is currently no clear consensus on staging or common approach...
Head and Neck
Wed Sep 02, 2020 13:25
HPV-EM: an accurate HPV detection and genotyping EM algorithm.
Related Articles HPV-EM: an accurate HPV detection and genotyping EM algorithm. Sci Rep. 2020 Aug 31;10(1):14340 Authors: Inkman MJ, Jayachandran K, Ellis TM, Ruiz F, McLellan MD, Miller CA, Wu Y, Ojesina AI, Schwarz JK, Zhang J Abstract Accurate HPV genotyping is crucial in facilitating epidemiology studies, vaccine trials, and HPV-related cancer research. Contemporary HPV genotyping assays only detect < 25% of all known HPV genotypes...
Head and Neck
Wed Sep 02, 2020 13:25
Common Carotid-to-Internal Jugular Arteriovenous Loop for Single-Stage Microsurgical Reconstruction in the Radiated Vessel-Depleted Neck: Description of Technique and Clinical Case Correlates.
Related Articles Common Carotid-to-Internal Jugular Arteriovenous Loop for Single-Stage Microsurgical Reconstruction in the Radiated Vessel-Depleted Neck: Description of Technique and Clinical Case Correlates. J Craniofac Surg. 2020 Aug 28;: Authors: Anderson SR, Scott BA, Harrison LM, Wimalawansa SM, Kadakia SP Abstract Management of head and neck defects in a radiated field can be quite challenging owing to the dearth of vasculature and...
Head and Neck
Wed Sep 02, 2020 13:25

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