JCM, Vol. 9, Pages 2845: Upper Respiratory Tract Microbiome and Otitis Media Intertalk: Lessons from the Literature Journal of Clinical Medicine doi: 10.3390/jcm9092845 Authors: Francesco Folino Luca Ruggiero Pasquale Capaccio Ilaria Coro Stefano Aliberti Lorenzo Drago Paola Marchisio Sara Torretta Otitis media (OM) is one of the most common diseases occurring during childhood. Microbiological investigations concerning this topic have been primarily focused on the...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2848: Comparison of 2-Year Outcomes between Intravitreal Ranibizumab and Intravitreal Aflibercept for Diabetic Macular Edema with “Treat-and-Extend” Regimen—Its Usefulness and Problems Journal of Clinical Medicine doi: 10.3390/jcm9092848 Authors: Shinichiro Chujo Masahiko Sugimoto Taku Sasaki Yoshitsugu Matsui Kumiko Kato Atsushi Ichio Ryohei Miyata Hisashi Matsubara Mineo Kondo Background: To compare the effectiveness of intravitreal ranibizumab...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2843: Fatty Acid Binding Protein 4—A Circulating Protein Associated with Peripheral Arterial Disease in Diabetic Patients Journal of Clinical Medicine doi: 10.3390/jcm9092843 Authors: Abdelrahman Zamzam Muzammil H. Syed Elisa Greco Mark Wheatcroft Shubha Jain Hamzah Khan Krishna K. Singh Thomas L. Forbes Ori Rotstein Rawand Abdin Mohammad Qadura Diabetic patients with peripheral arterial disease (PAD) often suffer from poor clinical outcomes...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2844: H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival Journal of Clinical Medicine doi: 10.3390/jcm9092844 Authors: Sayeh Saravi Eriko Katsuta Jeyarooban Jeyaneethi Hasnat A. Amin Matthias Kaspar Kazuaki Takabe George Pados Fotios Drenos Marcia Hall Emmanouil Karteris Background: H2AX can be of prognostic value in breast cancer, since in advanced...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2846: Impact of Serum Lipid on Breast Cancer Recurrence Journal of Clinical Medicine doi: 10.3390/jcm9092846 Authors: Sung Mi Jung Danbee Kang Eliseo Guallar Jonghan Yu Jeong Eon Lee Seok Won Kim Seok Jin Nam Juhee Cho Se Kyung Lee The association between serum lipid level and prognosis of breast cancer is controversial. The purpose of this study was to evaluate the impact of serum lipid level in breast cancer recurrence. We analyzed a total...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2841: Analysis of Risk Factors and Long-Term Outcomes in Kidney Transplant Patients with Identified Lymphoceles Journal of Clinical Medicine doi: 10.3390/jcm9092841 Authors: Lukas J. Lehner Arnim Hohberger Lisanne Marschke Nils Lachmann Robert Peters Frank Friedersdorff Dmytro Khadzhynov Fabian Halleck Klemens Budde Oliver Staeck Michael Duerr The collection of lymphatic fluids (lymphoceles) is a frequent adverse event following renal...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2842: Differentiating Females with Rett Syndrome and Those with Multi-Comorbid Autism Spectrum Disorder Using Physiological Biomarkers: A Novel Approach Journal of Clinical Medicine doi: 10.3390/jcm9092842 Authors: Nantia Iakovidou Evamaria Lanzarini Jatinder Singh Federico Fiori Paramala Santosh This study explored the use of wearable sensor technology to investigate autonomic function in children with autism spectrum disorder (ASD) and Rett syndrome (RTT)....
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2838: Drug-Induced Naïve iPS Cells Exhibit Better Performance than Primed iPS Cells with Respect to the Ability to Differentiate into Pancreatic β-Cell Lineage Journal of Clinical Medicine doi: 10.3390/jcm9092838 Authors: Yuki Kiyokawa Masahiro Sato Hirofumi Noguchi Emi Inada Yoko Iwase Naoko Kubota Tadashi Sawami Miho Terunuma Takeyasu Maeda Haruaki Hayasaki Issei Saitoh Pluripotent stem cells are classified as naïve and primed...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2837: The Effects of Human Visual Sensory Stimuli on N1b Amplitude: An EEG Study Journal of Clinical Medicine doi: 10.3390/jcm9092837 Authors: Damien Moore Toshikazu Ikuta Paul D. Loprinzi Sensory systems are widely known to exhibit adaptive mechanisms. Vision is no exception to input dependent changes in its sensitivity. Recent animal work demonstrates enhanced connectivity between neurons in the visual cortex. The purpose of the present experiment was to evaluate...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2839: Metformin Attenuates Osteoporosis in Diabetic Patients with Carcinoma in Situ: A Nationwide, Retrospective, Matched-Cohort Study in Taiwan Journal of Clinical Medicine doi: 10.3390/jcm9092839 Authors: Chieh-Hua Lu Chi-Hsiang Chung Feng-Chih Kuo Kuan-Chan Chen Chia-Hao Chang Chih-Chun Kuo Chien-Hsing Lee Sheng-Chiang Su Jhih-Syuan Liu Fu-Huang Lin Chang-Huei Tsao Po-Shiuan Hsieh Yi-Jen Hung Chang-Hsun Hsieh Wu-Chien Chien ...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2840: Clinical Impact of Corrections to Infliximab and Adalimumab Monitoring Results with the Homogeneous Mobility Shift Assay Journal of Clinical Medicine doi: 10.3390/jcm9092840 Authors: Konstantinos Papamichael Valerio J. Thomas Andrea Banty William T. Clarke Katharine A. Germansky Sarah N. Flier Joseph D. Feuerstein Gil Y. Melmed Adam S. Cheifetz An upward drift for both infliximab and adalimumab concentrations measured by the homogenous...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2836: Folate Insufficiency Due to MTHFR Deficiency Is Bypassed by 5-Methyltetrahydrofolate Journal of Clinical Medicine doi: 10.3390/jcm9092836 Authors: Maša Vidmar Golja Alenka Šmid Nataša Karas Kuželički Jurij Trontelj Ksenija Geršak Irena Mlinarič-Raščan Adequate levels of folates are essential for homeostasis of the organism, prevention of congenital malformations, and the salvage of predisposed disease states. They depend on genetic predisposition,...
Wed Sep 02, 2020 03:00
JCM, Vol. 9, Pages 2834: Perceptions, Attitudes, and Barriers to Obesity Management in Spain: Results from the Spanish Cohort of the International ACTION-IO Observation Study Journal of Clinical Medicine doi: 10.3390/jcm9092834 Authors: Javier Salvador Nuria Vilarrasa Francisco Poyato Miguel Ángel Rubio The prevalence of obesity is rapidly rising in Spain. The Awareness, Care and Treatment in Obesity Management—An International Observation (ACTION-IO) study (NCT03584191)...
Wed Sep 02, 2020 03:00
JFB, Vol. 11, Pages 61: Proton Conduction via Water Bridges Hydrated in the Collagen Film Journal of Functional Biomaterials doi: 10.3390/jfb11030061 Authors: Hiroshi Matsui Yasumitsu Matsuo Collagen films with proton conduction are a candidate of next generation of fuel-cell electrolyte. To clarify a relation between proton conductivity and formation of water networks in the collagen film originating from a tilapia’s scale, we systematically measured the ac conductivity,...
Wed Sep 02, 2020 03:00
JoF, Vol. 6, Pages 160: Intranasal Vaccine Using P10 Peptide Complexed within Chitosan Polymeric Nanoparticles as Experimental Therapy for Paracoccidioidomycosis in Murine Model Journal of Fungi doi: 10.3390/jof6030160 Authors: Samuel Rodrigues Dos Santos Junior Francenya Kelley Lopes da Silva Lucas Santos Dias Ana Camila Oliveira Souza Marcelo Valdemir de Araujo Leandro Buffoni Roque da Silva Luiz R. Travassos Andre Correa Amaral Carlos P. Taborda Paracoccidioidomycosis...
Wed Sep 02, 2020 03:00
Medical Sciences, Vol. 8, Pages 38: Association of Candidate Gene Polymorphism with Metabolic Syndrome among Mongolian Subjects: A Case-Control Study Medical Sciences doi: 10.3390/medsci8030038 Authors: Ariunbold Chuluun-Erdene Orgil Sengeragchaa Tsend-Ayush Altangerel Purevjal Sanjmyatav Batnaran Dagdan Solongo Battulga Lundiamaa Enkhbat Nyamjav Byambasuren Munkhzol Malchinkhuu Munkhtstetseg Janlav Metabolic syndrome (MetS) is complex and determined by the...
Wed Sep 02, 2020 03:00
Membranes, Vol. 10, Pages 221: Electrodialytic Processes: Market Overview, Membrane Phenomena, Recent Developments and Sustainable Strategies Membranes doi: 10.3390/membranes10090221 Authors: Laurent Bazinet Thibaud R. Geoffroy In the context of preserving and improving human health, electrodialytic processes are very promising perspectives. Indeed, they allow the treatment of water, preservation of food products, production of bioactive compounds, extraction of organic acids, and...
Wed Sep 02, 2020 03:00
Membranes, Vol. 10, Pages 220: Micellar-Enhanced Ultrafiltration Using a Plant-Derived Surfactant for Dye Separation in Wastewater Treatment Membranes doi: 10.3390/membranes10090220 Authors: Nita Aryanti Aininu Nafiunisa Tutuk Djoko Kusworo Dyah Hesti Wardhani Micellar-enhanced ultrafiltration (MEUF) is one of several membrane methods used for the removal of trace organic pollutants from aqueous streams. In this process, a surfactant is added to a polluted aqueous solution at...
Wed Sep 02, 2020 03:00
Metabolites, Vol. 10, Pages 360: An 1H NMR- and MS-Based Study of Metabolites Profiling of Garden Snail Helix aspersa Mucus Metabolites doi: 10.3390/metabo10090360 Authors: Nikolay G. Vassilev Svetlana D. Simova Miroslav Dangalov Lyudmila Velkova Venceslav Atanasov Aleksandar Dolashki Pavlinka Dolashka Metabolic profiling based on 1H nuclear magnetic resonance (NMR) spectroscopy was applied with the aim to investigate the functional role of the metabolites in lyophilized...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1344: Catabolic Reductive Dehalogenase Substrate Complex Structures Underpin Rational Repurposing of Substrate Scope Microorganisms doi: 10.3390/microorganisms8091344 Authors: Tom Halliwell Karl Fisher Karl A. P. Payne Stephen E. J. Rigby David Leys Reductive dehalogenases are responsible for the reductive cleavage of carbon-halogen bonds during organohalide respiration. A variety of mechanisms have been proposed for these cobalamin and [4Fe-4S]...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1341: Evaluation of the Biodegradation Efficiency of Four Various Types of Plastics by Pseudomonas aeruginosa Isolated from the Gut Extract of Superworms Microorganisms doi: 10.3390/microorganisms8091341 Authors: Hyun Min Lee Hong Rae Kim Eunbeen Jeon Hee Cheol Yu Sukkyoo Lee Jiaojie Li Dae-Hwan Kim Plastic waste worldwide is becoming a serious pollution problem for the planet. Various physical and chemical methods have been tested in attempts...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1342: Innate Lymphoid Cells: Important Regulators of Host–Bacteria Interaction for Border Defense Microorganisms doi: 10.3390/microorganisms8091342 Authors: Katharina Beck Hiroshi Ohno Naoko Satoh-Takayama Innate lymphoid cells (ILCs) are a recently discovered type of innate immune lymphocyte. They include three different groups classified by the nature of the transcription factors required for their development and by the cytokines they produce. ILCs...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1339: Metabolic Responses to Arsenite Exposure Regulated through Histidine Kinases PhoR and AioS in Agrobacterium tumefaciens 5A Microorganisms doi: 10.3390/microorganisms8091339 Authors: Rachel A. Rawle Monika Tokmina-Lukaszewska Zunji Shi Yoon-Suk Kang Brian P. Tripet Fang Dang Gejiao Wang Timothy R. McDermott Valerie Copie Brian Bothner Arsenite (AsIII) oxidation is a microbially-catalyzed transformation that directly impacts...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1340: Recognition of Candida albicans and Role of Innate Type 17 Immunity in Oral Candidiasis Microorganisms doi: 10.3390/microorganisms8091340 Authors: Anna Pavlova Irshad Sharafutdinov Candida albicans is an opportunistic pathogenic fungus considered to be a common member of the human microflora. Similar to some other opportunistic microbes, C. albicans can invade and benefit from its host when the immune status of that host is weakened. Most often...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1338: Antimicrobial Resistance Gene Detection and Plasmid Typing Among Multidrug Resistant Enterococci Isolated from Freshwater Environment Microorganisms doi: 10.3390/microorganisms8091338 Authors: Sohyun Cho John B. Barrett Jonathan G. Frye Charlene R. Jackson In this study, mechanisms of antimicrobial resistance (AR) as well as the abundance and diversity of plasmids were determined among multidrug resistant (MDR) enterococci from surface water...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1343: Bacterial Diversity and Antibiotic Susceptibility of Sparus aurata from Aquaculture Microorganisms doi: 10.3390/microorganisms8091343 Authors: Vanessa Salgueiro Vera Manageiro Narcisa M. Bandarra Lígia Reis Eugénia Ferreira Manuela Caniça In a world where the population continues to increase and the volume of fishing catches stagnates or even falls, the aquaculture sector has great growth potential. This study aimed to contribute to...
Wed Sep 02, 2020 03:00
Microorganisms, Vol. 8, Pages 1337: Soil Type Affects Organic Acid Production and Phosphorus Solubilization Efficiency Mediated by Several Native Fungal Strains from Mexico Microorganisms doi: 10.3390/microorganisms8091337 Authors: Dorcas Zúñiga-Silgado Julio C. Rivera-Leyva Jeffrey J. Coleman Ayixon Sánchez-Reyez Susana Valencia-Díaz Mario Serrano Luz E. de-Bashan Jorge L. Folch-Mallol Phosphorus (P) is considered a scarce macronutrient for plants in most tropical...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4014: Methods of Purification and Application Procedures of Alpha1 Antitrypsin: A Long-Lasting History Molecules doi: 10.3390/molecules25174014 Authors: Simona Viglio Paolo Iadarola Maura D’Amato Jan Stolk The aim of the present report is to review the literature addressing the methods developed for the purification of alpha1-antitrypsin (AAT) from the 1950s to the present. AAT is a glycoprotein whose main function is to protect tissues from human neutrophil...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4009: Synthesis of Potential Haptens with Morphine Skeleton and Determination of Protonation Constants Molecules doi: 10.3390/molecules25174009 Authors: István Köteles Károly Mazák Gergő Tóth Boglárka Tűz Sándor Hosztafi Vaccination could be a promising alternative warfare against drug addiction and abuse. For this purpose, so-called haptens can be used. These molecules alone do not induce the activation of the immune system, this occurs only when...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4013: Proteinoid Nanocapsules as Drug Delivery System for Improving Antipsychotic Activity of Risperidone Molecules doi: 10.3390/molecules25174013 Authors: Liroy Lugasi Igor Grinberg Rivka Sabag Ravit Madar Haim Einat Shlomo Margel Risperidone (RSP) is an atypical antipsychotic drug widely used to treat schizophrenia and bipolar disorder. Nanoparticles (NPs) are being developed as in vivo targeted drug delivery systems, which cross the blood-brain...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4012: Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy Molecules doi: 10.3390/molecules25174012 Authors: Romain Eychenne Christelle Bouvry Mickael Bourgeois Pascal Loyer Eric Benoist Nicolas Lepareur Identified in 1973, somatostatin (SST) is a cyclic hormone peptide with a short biological half-life. Somatostatin receptors (SSTRs) are widely expressed in the whole body, with five subtypes described. The interaction...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4015: Free Amino Acids in Three Pleurotus Species Cultivated on Agricultural and Agro-Industrial By-Products Molecules doi: 10.3390/molecules25174015 Authors: Dimitra Tagkouli Andriana Kaliora Georgios Bekiaris Georgios Koutrotsios Margarita Christea Georgios I. Zervakis Nick Kalogeropoulos Previous studies have demonstrated the feasibility of employing by-products of the olive and wine sectors for the production of Pleurotus mushrooms with...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4011: Development of a Molecular Snail Xenomonitoring Assay to Detect Schistosoma haematobium and Schistosoma bovis Infections in their Bulinus Snail Hosts Molecules doi: 10.3390/molecules25174011 Authors: Tom Pennance John Archer Elena Birgitta Lugli Penny Rostron Felix Llanwarne Said Mohammed Ali Amour Khamis Amour Khamis Rashid Suleiman Sarah Li David Rollinson Jo Cable Stefanie Knopp Fiona Allan Shaali Makame Ame Bonnie...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4010: A Lanosteryl Triterpene (RA-3) Exhibits Antihyperuricemic and Nephroprotective Effects in Rats Molecules doi: 10.3390/molecules25174010 Authors: Nomadlozi Blessings Hlophe Andrew Rowland Opoku Foluso Oluwagbemiga Osunsanmi Trayana Georgieva Djarova-Daniels Oladipupo Adejumobi Lawal Rebamang Anthony Mosa Considering the global health threat posed by kidney disease burden, a search for new nephroprotective drugs from our local flora could...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4007: Semi-Synthetic Approach Leading to 8-Prenylnaringenin and 6-Prenylnaringenin: Optimization of the Microwave-Assisted Demethylation of Xanthohumol Using Design of Experiments Molecules doi: 10.3390/molecules25174007 Authors: Corinna Urmann Herbert Riepl The isomers 8-prenylnaringenin and 6-prenylnaringenin, both secondary metabolites occurring in hops, show interesting biological effects, like estrogen-like, cytotoxic, or neuro regenerative activities....
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4004: Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules doi: 10.3390/molecules25174004 Authors: Jaeyoon Kim Soon Re Kim Yun-Ho Choi Jae young Shin Chang Deok Kim Nae-Gyu Kang Byung Cheol Park Sanghwa Lee The present study aimed to investigate the molecular mechanism of quercitrin, a major constituent of Hottuynia cordata extract, for its hair growth stimulating...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4008: Sunlight-Operated TiO2-Based Photocatalysts Molecules doi: 10.3390/molecules25174008 Authors: Irene Barba-Nieto Uriel Caudillo-Flores Marcos Fernández-García Anna Kubacka Photo-catalysis is a research field with broad applications in terms of potential technological applications related to energy production and managing, environmental protection, and chemical synthesis fields. A global goal, common to all of these fields, is to generate photo-catalytic...
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4006: Comprehensive Metabolome Analysis of Fermented Aqueous Extracts of Viscum album L. by Liquid Chromatography−High Resolution Tandem Mass Spectrometry Molecules doi: 10.3390/molecules25174006 Authors: Evelyn Peñaloza Carla Holandino Claudia Scherr Paula I. P. de Araujo Ricardo M. Borges Konrad Urech Stephan Baumgartner Rafael Garrett Fermented aqueous extracts of Viscum album L. are widely used for cancer treatment in complementary medicine....
Wed Sep 02, 2020 03:00
Molecules, Vol. 25, Pages 4005: Memantine Derivatives as Multitarget Agents in Alzheimer’s Disease Molecules doi: 10.3390/molecules25174005 Authors: Giambattista Marotta Filippo Basagni Michela Rosini Anna Minarini Memantine (3,5-dimethyladamantan-1-amine) is an orally active, noncompetitive N-methyl-D-aspartate receptor (NMDAR) antagonist approved for treatment of moderate-to-severe Alzheimer’s disease (AD), a neurodegenerative condition characterized by a progressive...
Wed Sep 02, 2020 03:00
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