The microbiome can contribute to variation in fitness-related traits of their hosts, and thus to host evolution. Hosts are therefore expected to be under selection to control their microbiome, for instance through controlling microbe transmission from parents to offspring. Current models have mostly focused on microbes that either increase or decrease fitness. In that case, host-level selection is relatively straightforward, favouring either complete or no inheritance. In natural systems, however,...
Wed Sep 02, 2020 03:00
Although the biomass of chum salmon (Oncorhynchus keta) in the North Pacific is at a historical maximum, the number of individuals returning to Japan, the location of the world largest chum salmon hatchery program, has declined substantially over 25 years. To search for potential causes of this decline, we synthesized catch/release, sea surface temperature (SST), and published genetic data, namely, microsatellites, single nucleotide polymorphisms collected for efficient stock identification, lactate...
Wed Sep 02, 2020 03:00
Molecular analyses of closely related taxa have increasingly revealed the importance of higher-order genetic interactions in explaining the observed pattern of reproductive isolation between populations. Indeed, both empirical and theoretical studies have linked the process of speciation to complex genetic interactions. Gene Regulatory Networks (GRNs) capture the inter-dependencies of gene expression and encode information about an individual's phenotype and development at the molecular level. As...
Wed Sep 02, 2020 03:00
Spatial and seasonal variation in the environment are ubiquitous. Environmental heterogeneity can affect natural populations and lead to covariation between environment and allele frequencies. Drosophila melanogaster is known to harbor polymorphisms that change both with latitude and seasons. Identifying the role of selection in driving these changes is not trivial, because non-adaptive processes can cause similar patterns. Given the environment changes in similar ways across seasons and along the...
Wed Sep 02, 2020 03:00
AO_SCPLOWBSTRACTC_SCPLOWGene paralogs are copies of a same gene that appear after gene or full genome duplication. Redundancy generated by gene duplication may release certain evolutionary pressures, allowing one of the copies to access novel gene functions. Here we focused on role of codon usage preferences (CUPrefs) during the evolution of the polypyrimidine tract binding protein (PTBP) splicing regulator paralogs. PTBP1-3 show high identity at the amino acid level (up to 80%), but display...
Wed Sep 02, 2020 03:00
Though seemingly bizarre, the dramatic post-embryonic transformation that occurs during metamorphosis is one of the most widespread and successful developmental strategies on the planet. The adaptive decoupling hypothesis (ADH) proposes that metamorphosis is an adaptation for optimizing expression of traits across life stages that experience opposing selection pressures. Similarly, sex-biased expression of traits is thought to evolve in response to sexually antagonistic selection. Both hypotheses...
Wed Sep 02, 2020 03:00
The relationship between microbiomes and selective regimes in the sponge genus Ircinia [NEW RESULTS]
Sponges are often densely populated by microbes that benefit their hosts through nutrition and bioactive secondary metabolites; however, sponges must simultaneously contend with the toxicity of microbes and thwart microbial overgrowth. Despite these fundamental tenets of sponge biology, the patterns of selection in the host sponge genomes that underlie tolerance and control of their microbiomes are still poorly understood. To elucidate these patterns of selection, we performed a population genetic...
Tue Sep 01, 2020 03:00
A novel coronavirus (SARS-CoV-2), causing an emerging coronavirus disease (COVID-19), first detected in Wuhan City, Hubei Province, China, which has taken a catastrophic turn with high toll rates in China and ...
Wed Sep 02, 2020 03:00
Majocchi's granuloma is an uncommon fungal infection of the dermis and subcutaneous tissue. The most frequently identified cause of Majocchi’s granuloma is anthropophilic Trichophyton rubrum, and it is most commo...
Wed Sep 02, 2020 03:00
The presence of a suspicious ovarian cyst with elevated cancer antigen 125 level in a woman of reproductive age poses a serious therapeutic dilemma. Mature cystic teratomas and mucinous cystadenomas may also c...
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Developmental disorder and dementia in older adults have been considered unrelated clinical entities because their timing of diagnosis differs greatly; however, recent studies have suggested an association bet...
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Mantle cell lymphoma is one of several subtypes of non-Hodgkin lymphoma. Cervical relapse of non-Hodgkin lymphoma is a very rare condition that has a variable and nonspecific presentation and may resemble othe...
Wed Sep 02, 2020 03:00
To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation ...
Tue Sep 01, 2020 03:00
Introduction: Semicircular canal dehiscence (SCD) is defined as a defect of the bone overlying the semicircular canal. It has a relatively high prevalence of 3% in the general population, which makes it likely that a certain number of patients receiving a cochlear implant (CI) would have it. However, little is known about the influence of SCD on the CI outcome. Therefore, the aim of this study was to determine the influence of SCD on CI outcome with regard to short- and long-term word perception...
Wed Sep 02, 2020 13:51
Introduction: Fluctuating hearing loss is a distinctive feature caused by SLC26A4 variants. We investigated whether cochlear implantation had protective or deleterious effect on hearing fluctuation in patients with biallelic SLC26A4 variants. Methods: Patients with biallelic SLC26A4 variants (N = 16; age = 10.24 ± 9.20 years) who had unilateral cochlear implantation and consecutive postsurgical, bilateral pure-tone audiograms more than 3 times were selected. We retrospectively reviewed the patients’...
Wed Sep 02, 2020 13:50
Background and Objectives: A rare type of nonsyndromic autosomal recessive hereditary hearing loss is caused by pathogenic mutations in the TRIOBP gene mostly involving exons 6 and 7. These mutations cause hearing loss originating from dysfunction of sensory inner ear hair cells. Of all the affected siblings, 2 brothers and 1 sister, part of an Afghan family, were referred to our clinic for diagnostic workup and candidacy selection for cochlear implantation (CI). Methods: Molecular analysis showed...
Wed Sep 02, 2020 12:59
Bacterial speck disease, which reduces both fruit yield and quality, has been a growing problem in tomatoes over the last five years. Because the culpable bacterium, Pseudomonas syringae, prefers a cool and wet climate, crops in places such as New York State have been particularly susceptible. Researchers have uncovered the first known gene to impart resistance to a particular strain of the bacterium that causes speck disease.
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Understanding how bacteria interact is critical to solving growing problems such as antibiotic resistance, in which infectious bacteria form defenses to thwart the medicines used to fight them. Researchers have discovered that bacterial cells from different species can combine into unique hybrid cells by fusing their cell walls and membranes and sharing cellular contents, including proteins and ribonucleic acid (RNA), the molecules which regulate gene expression and control cell metabolism.
Wed Sep 02, 2020 18:59
Scientists studying life on the surface of glaciers in the Arctic and Alps challenge assumptions on virus evolution. Their study shows that, contrary to expectations, the viruses on glaciers in the Alps, Greenland and Spitsbergen are remarkably stable in the environment.
Wed Sep 02, 2020 16:51
Abstract Clinical studies have extensively shown that burst fractures can cause severe and long-term neurological deficits. However, the mechanism of burst fracture is not clear, and the influence of different spinal postures on burst fracture is still unidentified. The study aimed at investigating the influence of different postures under vertical impact load on thoracolumbar burst fracture. A detailed nonlinear finite element model of T12-L2 segment was developed to investigate...
Wed Sep 02, 2020 03:00
The purpose of this investigation was to observe laryngeal tissue and vocal function changes over the course of 28 days in a single participant diagnosed by a laryngologist with bilateral nodules. Laryngeal imaging, acoustic variables and perceptual assessments of voice quality, and perceived vocal effort were obtained every morning for 28 consecutive days. A daily journal of occupational and recreational voice use as well as menstruation and alcohol consumption was maintained each day. It was hypothesized...
Wed Sep 02, 2020 03:00
Recurrent respiratory papillomatosis (RRP) is characterized by recurrent laryngeal papillomas and treated with repeated surgical excision. The human papillomavirus (HPV) vaccine prevents infection with strains of HPV unrelated to RRP, and has recently been shown to increase the interval between surgeries when used as an adjuvant. The objective of this study was to report one case from our institution in which HPV vaccination was found to induce spontaneous regression of disease, absent of surgical...
Wed Sep 02, 2020 03:00
Performing vocal warm-ups prior to singing repertoire has been shown to change the perceived quality and acoustic parameters of the voice. To date, there are no studies that specifically compare singers’ and listeners’ perceptions of vocal quality after various warm-up durations.
Wed Sep 02, 2020 03:00
Abstract Translocated populations must adapt to their new environment to survive. A key aspect of survival for insects is the maintenance of water balance. It is thought that insects can adapt to dry environments by adjusting their cuticular hydrocarbon (CHC) profile to reduce water loss, though there is limited empirical support for this, and studies generally focus on other roles of CHCs, such as chemical communication. We tested for phenotypic adaptation in introduced populations...
Wed Sep 02, 2020 03:00
Abstract Population density modulates a wide range of eco-evolutionary processes including inter- and intra-specific competition, fitness and population dynamics. In holometabolous insects, the larval stage is particularly susceptible to density-dependent effects because the larva is the resource-acquiring stage. Larval density-dependent effects can modulate the expression of life-history traits not only in the larval and adult stages but also downstream for population dynamics...
Wed Sep 02, 2020 03:00
Abstract Introduction Bone turnover markers (BTMs) can be used to monitor bone metabolism, while the actual clinical changing in hip fracture had not been certified to evaluate the changes of BTMs during the healing process after surgery of elderly hip fractures; and to get the effects of operation type, gender, serum 25(OH)D level, and age on bone turnover markers. Materials...
Wed Sep 02, 2020 03:00
Abstract Introduction The specific aims of the study were to compare possible differences in sclerostin and preadipocyte factor-1 (Pref-1) between rhythmic gymnasts (RG), swimmers (SW) and untrained controls (UC), and to investigate the relationships of sclerostin and Pref-1 with bone mineral characteristics in studied groups. Materials and methods ...
Wed Sep 02, 2020 03:00
Abstract The Developmental Origins of Health and Disease (DOHaD) hypothesis derives from the epidemiological and basic/mechanistic health sciences. This well‐supported hypothesis holds that environment during the earliest stages of life—pre‐conception, pregnancy, infancy—shapes developmental trajectories and ultimately health outcomes across the lifespan. Evolutionary anthropologists from multiple subdisciplines are embracing synergies between the DOHaD framework and developmentalist approaches...
Wed Sep 02, 2020 20:44
The aim of this study was to evaluate the application of cocoa pulp as an adjunct for malt in beer production. The cocoa pulp was analyzed for humidity, proteins, lipids, sugars, total soluble solids, organic acids, and minerals. A study was carried out to reduce the cocoa pulp viscosity by enzymatic depectinization, making its use viable in beer production. The cocoa pulp showed relevant quantities of compounds important in fermentation, such as sugars, acids, and minerals. In fermentation using...
Wed Sep 02, 2020 17:50
We are in the midst of a global crisis and a national reckoning. As we move toward then end of our pandemic summer, with countries opening back up and protests sparking worldwide as folks fight for the right of Black communities to live freely without fear and prejudice, one can question what these tumultuous events mean for the future of our species. I had the chance to speak with Agustín Fuentes, former chair of the Anthropology Department at the University of Notre Dame and incoming professor...
Wed Sep 02, 2020 21:30
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