Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Δευτέρα 13 Ιουλίου 2020


Iso‐Kikuchi syndrome with Y‐shaped bifurcation of the distal phalanx of the index fingers
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:44
Disseminated panniculitis with subcutaneous abscesses and fat necrosis associated with alpha‐1 antitrypsin deficiency
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:44
Videodermoscopic clues for scabies diagnosis and assessment of therapeutic efficacy
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:44
Histoid leprosy in a young man
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:43
Treatment of segmental lichen aureus in the pediatric age with a 755 nm alexandrite picosecond laser. A new therapeutic approach for pigmented purpuric dermatosis
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:43
Dermatological recommendations on hand hygiene in schools during the COVID‐19 pandemic
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:43
Localized leishmaniasis treated with intralesional meglumine antimoniate
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:43
Intensive short‐term schema therapy intervention in a patient with psoriasis – case report and clinical management
Wiley: JDDG: Journal der Deutschen Dermatologischen Gesellschaft: Table of Contents
Sun Jul 12, 2020 20:43
The effectiveness of an actuator-driven pulsed water jet for the removal of artificial dental calculus: a preliminary study
Abstract Background While hand and ultrasonic scalers are the primary tools used for the removal of dental calculus in periodontal treatment, many studies have shown that they also damage the enamel surface. We have developed a novel actuator-driven pulsed water jet (ADPJ) system, which has the ability to selectively remove materials depending on their stiffness. Considering the different material properties between teeth and...
Latest Results for BMC Oral Health
Mon Jul 13, 2020 03:00
Noninvasive assessment of abdominal adipose tissues and quantification of hepatic and pancreatic fat fractions in type 2 diabetes mellitus
Publication date: Available online 12 July 2020Source: Magnetic Resonance ImagingAuthor(s): Manoj Kumar Sarma, Andres Saucedo, Christine Hema Darwin, Ely Richard Felker, Kavya Umachandran, Daniel Kohanghadosh, Edward Xu, Steve Raman, Michael Albert Thomas
Magnetic Resonance Imaging
Mon Jul 13, 2020 16:04
Towards a general framework for fast and feasible <em>k</em>-space trajectories for MRI based on projection methods
Publication date: Available online 12 July 2020Source: Magnetic Resonance ImagingAuthor(s): Shubham Sharma, Mario Coutino, Sundeep Prabhakar Chepuri, Geert Leus, K.V.S. Hari
Magnetic Resonance Imaging
Mon Jul 13, 2020 16:04
Clinical Outcome of Exclusive Endoscopic Tympanoplasty with Porcine Small Intestine Submucosa in 72 Patients
ABSTRACT This study reports 6‐month follow‐up hearing results and graft take rate of 72 patients diagnosed with simple chronic otitis media receiving transcanal endoscopic tympanoplasty with porcine small intestine submucosa (SIS) xenograft (Biodesign). This xerograft eliminates donor site morbidity and reduces the operation time of graft harvesting. Hence, SIS provides a relatively convenient and time‐saving method to pursue a tissue graft for perforations repair. Results showed an overall success...
Wiley: Clinical Otolaryngology: Table of Contents
Mon Jul 13, 2020 12:44
Issue Information
International Journal for Numerical Methods in Biomedical Engineering
Wed Jul 08, 2020 21:07
Cover Image
The cover image is based on the Original Article A pilot in‐silico modeling‐based study of the pathological effects on the biomechanical function of tricuspid valves by Chung‐Hao Lee, Devin Laurence, Emily Johnson et al., https://doi.org/10.1002/cnm.3346.
International Journal for Numerical Methods in Biomedical Engineering
Wed Jul 08, 2020 21:07
ESTRO ACROP guidelines for Target Volume Definition in the thoracic radiation treatment of Small cell lung cancer
Publication date: Available online 13 July 2020Source: Radiotherapy and OncologyAuthor(s): Cecile Le Pechoux, Corinne Faivre-Finn, Sara Ramella, Fiona McDonald, Farkhad Manapov, Paul Martin Putora, Ben Slotman, Dirk De Ruysscher, Umberto Ricardi, Xavier Geets, José Belderbos, Christoph Pöttgen, Rafal Dziadiuszko, Stephanie Peeters, Yolande Lievens, Coen Hurkmans, Paul Van Houtte, Ursula Nestle
Radiotherapy and Oncology
Mon Jul 13, 2020 15:49
Letter to the editor regarding the article “Selection of a high-level physician may help improve outcomes of nasopharyngeal carcinoma” by Fei et al
Publication date: Available online 13 July 2020Source: Radiotherapy and OncologyAuthor(s): Chai Hong Rim
Radiotherapy and Oncology
Mon Jul 13, 2020 15:49
The importance of IL-6 blockade beyond the COVID-19 pandemic: consideration for cancer care
Publication date: Available online 13 July 2020Source: Radiotherapy and OncologyAuthor(s): Giuseppe Carlo Iorio, Umberto Ricardi, Pierfrancesco Franco
Radiotherapy and Oncology
Mon Jul 13, 2020 15:49
Response to Chai’ letter: What caused the difference in prognosis among different physicians?
Publication date: Available online 13 July 2020Source: Radiotherapy and OncologyAuthor(s): Xiufang Qiu, Ting Xu, Mengying Li, Zhaodong Fei, Chuanben Chen
Radiotherapy and Oncology
Mon Jul 13, 2020 15:49
Biophotonics methods for functional monitoring of complications of diabetes mellitus
The prevalence of diabetes omplications is a significant public health problem with a considerable economic cost. Thus, the timely diagnosis of complications and prevention of their development will contribute to increasing the length and quality of patient life, and reducing the economic costs of their treatment. This article aims to review the current state‐of‐the‐art biophotonics technologies used to identify the complications of diabetes mellitus and assess the quality of their treatment. Additionally,...
Journal of Biophotonics
Sun Jul 12, 2020 21:53
Automated Relative Fundamental Frequency Algorithms for Use With Neck-Surface Accelerometer Signals.
Related Articles Automated Relative Fundamental Frequency Algorithms for Use With Neck-Surface Accelerometer Signals. J Voice. 2020 Jul 08;: Authors: Groll MD, Vojtech JM, Hablani S, Mehta DD, Buckley DP, Noordzij JP, Stepp CE Abstract OBJECTIVE: Relative fundamental frequency (RFF) has been suggested as a potential acoustic measure of vocal effort. However, current clinical standards for RFF measures require time-consuming manual markings....
Technologies in Treatment of Head & Neck
Mon Jul 13, 2020 15:32
FDG-PET/CT Radiomics Models for The Early Prediction of Loco-regional Recurrence in Head and Neck Cancer.
Related Articles FDG-PET/CT Radiomics Models for The Early Prediction of Loco-regional Recurrence in Head and Neck Cancer. Curr Med Imaging. 2020 Jul 12;: Authors: Cong H, Peng W, Tian Z, Vallières M, Chuanpei X, Aijun Z, Benxin Z Abstract Purpose Both CT and PET radiomics is considered as a potential prognostic biomarker in head and neck cancer. This study investigate the value of fused pre-treatment functional imaging (18F-FDG PET/CT) radiomics...
Technologies in Treatment of Head & Neck
Mon Jul 13, 2020 15:32
Dysphagia following non-traumatic subarachnoid haemorrhage: A prospective pilot study.
Related Articles Dysphagia following non-traumatic subarachnoid haemorrhage: A prospective pilot study. Int J Lang Commun Disord. 2020 Jul 12;: Authors: Dunn K, Rumbach A, Finch E Abstract BACKGROUND: Whilst dysphagia is a commonly reported complication of stroke, it has received relatively little attention in the literature for patients following non-traumatic subarachnoid haemorrhage (SAH). AIMS: To investigate dysphagia incidence,...
Dysphagia - Rehabilitation
Mon Jul 13, 2020 15:18
Dysphagia Care Across the Continuum: A Multidisciplinary Dysphagia Research Society Taskforce Report of Service-Delivery During the COVID-19 Global Pandemic.
Related Articles Dysphagia Care Across the Continuum: A Multidisciplinary Dysphagia Research Society Taskforce Report of Service-Delivery During the COVID-19 Global Pandemic. Dysphagia. 2020 Jul 11;: Authors: Miles A, Connor NP, Desai RV, Jadcherla S, Allen J, Brodsky M, Garand KL, Malandraki GA, McCulloch TM, Moss M, Murray J, Pulia M, Riquelme LF, Langmore SE Abstract At the time of writing this paper, there are over 11 million reported cases...
Dysphagia - Rehabilitation
Mon Jul 13, 2020 15:18
Dysphagia in Lateral Medullary Syndrome: A Narrative Review.
Related Articles Dysphagia in Lateral Medullary Syndrome: A Narrative Review. Dysphagia. 2020 Jul 11;: Authors: Jang SH, Kim MS Abstract Dysphagia is a common clinical feature of lateral medullary syndrome (LMS) and is clinically relevant because it is related to aspiration pneumonia, malnutrition, increased mortality, and prolonged hospital stay. Herein, the pathophysiology, prognosis, and treatment of dysphagia in LMS are reviewed. The pathophysiology,...
Dysphagia - Rehabilitation
Mon Jul 13, 2020 15:18
A novel <em>STING1</em> variant causes a recessive form of STING-associated vasculopathy with onset in infancy (SAVI)
Publication date: Available online 13 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Bin Lin, Roberta Berard, Abdulrahman Al Rasheed, Buthaina Aladba, Philip J. Kranzusch, Maggie Henderlight, Alexi Grom, Dana Kahle, Sofia Torreggiani, Alexander G. Aue, Jacob Mitchell, Adriana A. de Jesus, Grant S. Schulert, Raphaela Goldbach-Mansky
Allergy and Clinical Immunology
Mon Jul 13, 2020 15:15
CD4<sup>+</sup>CD25<sup>high</sup>CD226<sup>low/-</sup>: An innovative approach to identify human regulatory T cells
Publication date: Available online 12 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Yu Liu, Guangying Qi, Julie Wang, Feng Huang, Joseph A. Bellanti, Song Guo Zheng
Allergy and Clinical Immunology
Mon Jul 13, 2020 15:15
Pneumocystis jirovecii Pneumonia in a HIV-Infected Patient with a CD4 Count Greater Than 400 Cells/μL and Atovaquone Prophylaxis
We describe a rare case of Pneumocystis jirovecii pneumonia (PCP) in a heterosexual man with a pertinent medical history of well-controlled human immunodeficiency virus (HIV) on highly active antiretroviral therapy (HAART) and PCP prophylaxis with atovaquone. The patient presented with recurrent shortness of breath, worsening malaise, and fever, following treatment for hypersensitivity pneumonitis one month prior, including a twenty-four-day course of 40 milligrams daily glucocorticoid with taper....
Case Reports in Infectious Diseases
Mon Jul 13, 2020 05:05
Static Computer‐Aided, Partially Guided and Free‐Handed Implant Placement: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
ABSTRACT Objective To analyze the outcomes of static computer‐aided implant placement (sCAIP) compared to partially guided (PGIP) and free‐handed (FHIP) implant placement. Material and Methods This study was registered in PROSPERO (CRD42019131397). A comprehensive literature search was performed by two independent examiners. Only randomized controlled trials (RCTs) were selected. Treatment modalities included sCAIP, PGIP and FHIP. Data pertaining to the outcomes of interest were extracted....
Clinical Oral Implants Research
Sun Jul 12, 2020 15:20
49,XXXXY syndrome: A study of neurological function in this uncommon X and Y chromosomal disorder
Abstract 49,XXXXY is a rare chromosomal variation characterized by deficits in motor, language, and cognitive domains. This study reports on the neurological function and dysmorphic features in the largest cohort to date. Seventy‐two boys with 49,XXXXY were evaluated on a variety of domains including a neurological examination and neuromotor assessments including the Beery Buktenica Developmental Test of Visual‐Motor Integration, Sixth Edition, the Bayley Scales of Infant and Toddler Development,...
American Journal of Medical Genetics Part A
Mon Jul 13, 2020 11:37
Short stature and growth hormone deficiency in a subset of patients with Potocki–Lupski syndrome: Expanding the phenotype of PTLS
Abstract Potocki–Lupski Syndrome (PTLS, MIM 610883), or duplication of chromosome 17p11.2, is a clinically recognizable condition characterized by infantile hypotonia, failure to thrive, developmental delay, intellectual disability, and congenital anomalies. Short stature, classified as greater than two standard deviations below the mean, has not previously been considered a major feature of PTLS. Retrospective chart review on a cohort of 37 individuals with PTLS was performed to investigate the...
American Journal of Medical Genetics Part A
Mon Jul 13, 2020 11:30
Heterozygous missense variant in EIF6 gene: A novel form of Shwachman–Diamond syndrome?
Abstract Shwachman–Diamond syndrome (SDS) is a rare multisystem ribosomal biogenesis disorder characterized by exocrine pancreatic insufficiency, hematologic abnormalities and bony abnormalities. About 90% of patients have biallelic mutations in SBDS gene. Three additional genes—EFL1, DNAJC21 and SRP54 have been reported in association with a SDS phenotype. However, the cause remains unknown for ~10% of patients. Herein, we report a 6‐year‐old Chinese boy, who presented in the neonatal period...
American Journal of Medical Genetics Part A
Mon Jul 13, 2020 11:28
DYNC1H1‐related disorders: A description of four new unrelated patients and a comprehensive review of previously reported variants
Abstract Heterozygous variants in the DYNC1H1 gene have been associated chiefly with intellectual disability (ID), malformations in cortical development (MCD), spinal muscular atrophy (SMA), and Charcot–Marie‐Tooth axonal type 20 (CMT), with fewer reports describing other intersecting phenotypes. To better characterize the variable syndromes associated with DYNC1H1 , we undertook a detailed analysis of reported patients in the medical literature through June 30, 2019. In sum we identified 200 patients...
American Journal of Medical Genetics Part A
Mon Jul 13, 2020 11:08
Introduction: Comprehensive investigation into an international cohort of boys with 49,XXXXY
American Journal of Medical Genetics Part A
Mon Jul 13, 2020 11:04
The role of tumour biomarkers in choosing the appropriate positron emission tomography imaging in follow‐up of medullary thyroid cancer
Abstract Introduction We aimed to demonstrate the importance of serum calcitonin (Ct) and carcinoembryonic‐antigen (CEA) levels in the selection of appropriate positron emission tomography/computed tomography (PET/CT) modality in the follow‐up of operated patients with medullary thyroid cancer. Methods Fourteen operated patients (8 Female, 6 Male) with MTC underwent PET/CT imaging with somatostatin (68Ga‐DOTATATE) and glucose (18FDG) analogs due to elevated Ct or CEA at follow‐up. Ct and...
Journal of Medical Imaging and Radiation Oncology
Sun Jul 12, 2020 20:19
Corneal Perforation Self-Healing with an Iris Plug in the Cornea
Keratitis treatment outcome is usually dependent on the targeted treatment of the cause. We want to present a small corneal ulcer of unidentified origin that progressed into corneal melting and resulted in corneal perforation. The patient had a widespread antibacterial and fungal treatment and an ophthalmological follow-up with slit-lamp examination and AS-OCT. The spontaneous iris plug in the cornea helped to solve the anterior chamber collapse and made permanent anatomical changes in the anterior...
Case Reports in Ophthalmology
Mon Jul 13, 2020 09:20
Ocular Myasthenia Gravis with Severe Blepharitis and Ocular Surface Disease: A Case Report
Ocular myasthenia gravis (OMG) is an autoimmune disease of the neuromuscular junction and commonly associated with other immune diseases. We describe a 16-year-old female who presented to our clinic with 1-month complaints of diplopia and strabismus, visual acuity deterioration, and ocular irritation. Her examination showed crossed diplopia and alternating exotropia of 25 prism diopters, severe blepharitis, conjunctival hyperemia, corneal pannus, epithelial irregularities, and subepithelial opacities....
Case Reports in Ophthalmology
Mon Jul 13, 2020 09:19
Infantile Digital Fibromatosis Successfully Treated with Topical %5 Imiquimod combined with %0,1 Methylprednisolone Aceponate
Wiley: Dermatologic Therapy: Table of Contents
Mon Jul 13, 2020 12:30
Omalizumab for cholinergic urticaria: 6 months prospective study and systematic review of the literature
Abstract Aim To examine the effectiveness of omalizumab on disease activity and quality of life in patients with cholinergic urticaria (CholU). Further, a systematic review of the literature was performed to identify all studies of use of omalizumab in CholU. Results A total of 23 patients (63.9%) were refractory to updosed non‐sedating antihistamines and initiated omalizumab in the observation period. Among these, an improvement of 10.8 UAS7 points (4.6‐17.0), p=0.002, was seen at 6 months...
Wiley: Dermatologic Therapy: Table of Contents
Sun Jul 12, 2020 21:43
Cancer-associated mutations in normal human endometrium: Surprise or expected?
Related Articles Cancer-associated mutations in normal human endometrium: Surprise or expected? Cancer Sci. 2020 Jul 12;: Authors: Kyo S, Sato S, Nakayama K Abstract The human endometrium is an essential component in human reproduction that has the unique characteristic of undergoing cyclic regeneration during each menstrual cycle. Vigorous regeneration after shedding may be sustained by stem/progenitor cells, for which molecular markers have...
Rare Cancers
Mon Jul 13, 2020 14:38

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