Molecules, Vol. 25, Pages 3193: High Throughput Virtual Screening to Discover Inhibitors of the Main Protease of the Coronavirus SARS-CoV-2 Molecules doi: 10.3390/molecules25143193 Authors: Olujide O. Olubiyi Maryam Olagunju Monika Keutmann Jennifer Loschwitz Birgit Strodel We use state-of-the-art computer-aided drug design (CADD) techniques to identify prospective inhibitors of the main protease enzyme, 3CLpro of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3192: Extraction of Lipids from Liquid Biological Samples for High-Throughput Lipidomics Molecules doi: 10.3390/molecules25143192 Authors: Samuel Furse Adam J. Watkins Albert Koulman Extraction of the lipid fraction is a key part of acquiring lipidomics data. High-throughput lipidomics, the extraction of samples in 96w plates that are then run on 96 or 384w plates, has particular requirements that mean special development work is needed to fully optimise...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3191: A Brief Overview on Antioxidant Activity Determination of Silver Nanoparticles Molecules doi: 10.3390/molecules25143191 Authors: Zdenka Bedlovičová Imrich Strapáč Matej Baláž Aneta Salayová Our objective in this review article is to find out relevant information about methods of determination of antioxidant activity of silver nanoparticles. There are many studies dealing with mentioned problem and herein we summarize the knowledge about methods...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3190: Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer’s Disease Therapy Molecules doi: 10.3390/molecules25143190 Authors: Lazhar Zribi Irene Pachòn-Angona Òscar M. Bautista-Aguilera Daniel Diez-Iriepa José Marco-Contelles Lhassane Ismaili Isabel Iriepa Fakher Chabchoub Alzheimer’s disease (AD) is multifactorial disease characterized by the accumulation of abnormal extracellular deposits of...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3194: Caernohabditis elegans as a Model Organism to Evaluate the Antioxidant Effects of Phytochemicals Molecules doi: 10.3390/molecules25143194 Authors: Begoña Ayuda-Durán Susana González-Manzano Ana M. González-Paramás Celestino Santos-Buelga The nematode Caernohabditis elegans was introduced as a model organism in biological research by Sydney Brenner in the 1970s. Since then, it has been increasingly used for investigating processes such as ageing,...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3188: Design, Facile Synthesis and Characterization of Dichloro Substituted Chalcones and Dihydropyrazole Derivatives for Their Antifungal, Antitubercular and Antiproliferative Activities Molecules doi: 10.3390/molecules25143188 Authors: Afzal B. Shaik Richie R. Bhandare Srinath Nissankararao Zehra Edis N. Ravikiran Tangirala Shaik Shahanaaz M. Mukhlesur Rahman Infectious diseases caused by fungi and mycobacteria pose an important problem for...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3186: Antioxidant, Antimicrobial, and Other Biological Properties of Pompia Juice Molecules doi: 10.3390/molecules25143186 Authors: Antonio Barberis Monica Deiana Ylenia Spissu Emanuela Azara Angela Fadda Pier Andrea Serra Guy D’hallewin Marina Pisano Gabriele Serreli Germano Orrù Alessandra Scano Daniela Steri Enrico Sanjust Pompia is a Citrus species belonging to Sardinian endemic biodiversity. Health benefits were attributed...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3189: 4,5-Diazafluorene and 9,9’-Dimethyl-4,5-Diazafluorene as Ligands Supporting Redox-Active Mn and Ru Complexes Molecules doi: 10.3390/molecules25143189 Authors: Wade C. Henke Julie A. Hopkins Micah L. Anderson Jonah P. Stiel Victor W. Day James D. Blakemore 4,5-diazafluorene (daf) and 9,9’-dimethyl-4,5-diazafluorene (Me2daf) are structurally similar to the important ligand 2,2’-bipyridine (bpy), but significantly less is...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3187: 4-Arylthieno[2,3-b]pyridine-2-carboxamides Are a New Class of Antiplasmodial Agents Molecules doi: 10.3390/molecules25143187 Authors: Sandra I. Schweda Arne Alder Tim Gilberger Conrad Kunick Malaria causes hundreds of thousands of deaths every year, making it one of the most dangerous infectious diseases worldwide. Because the pathogens have developed resistance against most of the established anti-malarial drugs, new antiplasmodial agents are...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3184: Syntheses and Reactivity of New Zwitterionic Imidazolium Trihydridoborate and Triphenylborate Species Molecules doi: 10.3390/molecules25143184 Authors: Maura Pellei Riccardo Vallesi Luca Bagnarelli H. V. Rasika Dias Carlo Santini In this study, four new N-(alkyl/aryl)imidazolium-borates were prepared, and their deprotonation reactions were investigated. Addition of BH3•THF to N-benzylimidazoles and N-mesitylimidazoles leads to imidazolium-trihydridoborate...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3185: Effect of Naringenin and Its Derivatives on the Probing Behavior of Myzus persicae (Sulz.) Molecules doi: 10.3390/molecules25143185 Authors: Katarzyna Stec Joanna Kozłowska Anna Wróblewska-Kurdyk Bożena Kordan Mirosław Anioł Beata Gabryś Substances that alter insect behavior have attracted a lot of attention as potential crop protection agents. Naringenin (5,7,4′-trihydroxyflavanone) is a naturally occurring bioactive flavanone....
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3182: Versatile Polypeptide-Functionalized Plasmonic Paper as Synergistic Biocompatible and Antimicrobial Nanoplatform Molecules doi: 10.3390/molecules25143182 Authors: Leopold Tie Mina Răileanu Mihaela Bacalum Irina Codita Ștefania Mădălina Negrea Costin Ștefan Caracoti Elena-Carmina Drăgulescu Andreea Campu Simion Astilean Monica Focsan Nowadays, thanks to nanotechnological progress, which itself guides us more and more closely toward...
Mon Jul 13, 2020 03:00
Molecules, Vol. 25, Pages 3183: New Copper(I) Complex with a Coumarin as Ligand with Antibacterial Activity against Flavobacterium psychrophilum Molecules doi: 10.3390/molecules25143183 Authors: Maialen Aldabaldetrecu Mick Parra Sarita Soto Pablo Arce Mario Tello Juan Guerrero Brenda Modak A new copper (I) complex, [Cu(NN1)2](ClO4), was synthesized, where NN1 was a imine ligand 6-((quinolin-2-ylmethylene)amino)-2H-chromen-2-one obtained by a derivatization of natural...
Mon Jul 13, 2020 03:00
Nanomaterials, Vol. 10, Pages 1367: Low Water Absorption, High-Strength Polyamide 6 Composites Blended with Sustainable Bamboo-Based Biochar Nanomaterials doi: 10.3390/nano10071367 Authors: Shiliu Zhu Yong Guo Yuxia Chen Shengquan Liu To promote the application of polyamide 6 (PA6) in wood–plastic composites, the negative effects associated with the thermal degradation of plant fibers must be overcome. In this study, waste bamboo fibers were subjected to pyrolysis...
Mon Jul 13, 2020 03:00
Nanomaterials, Vol. 10, Pages 1365: Effects of Different TiO2 Nanoparticles Concentrations on the Physical and Antibacterial Activities of Chitosan-Based Coating Film Nanomaterials doi: 10.3390/nano10071365 Authors: Yage Xing Xuanlin Li Xunlian Guo Wenxiu Li Jianwen Chen Qian Liu Qinglian Xu Qin Wang Hua Yang Yuru Shui Xiufang Bi In this investigation, the effect of different concentrations of titanium dioxide (TiO2) nanoparticles (NPs) on the structure...
Mon Jul 13, 2020 03:00
Nanomaterials, Vol. 10, Pages 1366: Nanoparticles in Targeted Alpha Therapy Nanomaterials doi: 10.3390/nano10071366 Authors: Agnieszka Majkowska-Pilip Weronika Gawęda Kinga Żelechowska-Matysiak Kamil Wawrowicz Aleksander Bilewicz Recent advances in the field of nanotechnology application in nuclear medicine offer the promise of better therapeutic options. In recent years, increasing efforts have been made on developing nanoconstructs that can be used as carriers for immobilising...
Mon Jul 13, 2020 03:00
Nanomaterials, Vol. 10, Pages 1364: Dielectrophoretic Crossover Frequency of Single Particles: Quantifying the Effect of Surface Functional Groups and Electrohydrodynamic Flow Drag Force Nanomaterials doi: 10.3390/nano10071364 Authors: Yun-Wei Lu Chieh Sun Ying-Chuan Kao Chia-Ling Hung Jia-Yang Juang We present a comprehensive comparison of dielectrophoretic (DEP) crossover frequency of single particles determined by various experimental methods and theoretical models under...
Mon Jul 13, 2020 03:00
Nanomaterials, Vol. 10, Pages 1363: 3D Networks of Ge Quantum Wires in Amorphous Alumina Matrix Nanomaterials doi: 10.3390/nano10071363 Authors: Lovro Basioli Marija Tkalčević Iva Bogdanović-Radović Goran Dražić Peter Nadazdy Peter Siffalovic Krešimir Salamon Maja Mičetić Recently demonstrated 3D networks of Ge quantum wires in an alumina matrix, produced by a simple magnetron sputtering deposition enables the realization of nanodevices with tailored conductivity...
Mon Jul 13, 2020 03:00
ncRNA, Vol. 6, Pages 29: Potential miRNAs for miRNA-Based Therapeutics in Breast Cancer Non-Coding RNA doi: 10.3390/ncrna6030029 Authors: Jun Sheng Wong Yoke Kqueen Cheah MicroRNAs (miRNAs) are small non-coding RNAs that can post-transcriptionally regulate the genes involved in critical cellular processes. The aberrant expressions of oncogenic or tumor suppressor miRNAs have been associated with cancer progression and malignancies. This resulted in the dysregulation of signaling pathways...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2070: Comment on: “Changes in Skeletal Muscle Glycogen Content in Professional Soccer Players before and after a Match by a NonInvasive MuscleSound® Technology. A Cross Sectional Pilot Study Nutrients 2020, 12(4), 971” Nutrients doi: 10.3390/nu12072070 Authors: Niels Ørtenblad Joachim Nielsen Kasper D. Gejl Harry E. Routledge James P. Morton Graeme L. Close David C. Niemann Julia L. Bone Louise M. Burke San-Millán and colleagues...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2073: Dietary Intake Influences Metabolites in Healthy Infants: A Scoping Review Nutrients doi: 10.3390/nu12072073 Authors: Mara L. Leimanis Laurens Chana Kraus-Friedberg Wreeti Kar Dominic Sanfilippo Surender Rajasekaran Sarah S. Comstock Metabolites are generated from exogenous sources such as diet. This scoping review will summarize nascent metabolite literature and discriminating metabolites for formula vs. human- milk-fed infants. Using the...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2077: Inhalation of Patchouli (Pogostemon Cablin Benth.) Essential Oil Improved Metabolic Parameters in Obesity-Induced Sprague Dawley Rats Nutrients doi: 10.3390/nu12072077 Authors: Seong Jun Hong Jinju Cho Chang Guk Boo Moon Yeon Youn Jeong Hoon Pan Jae Kyeom Kim Eui-Cheol Shin This study investigated effects of patchouli essential oil (PEO) inhalation on metabolic parameters. First, to characterize aromatic compounds in PEO, solid-phase...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2075: Osteoprotective Activity and Metabolite Fingerprint via UPLC/MS and GC/MS of Lepidium sativum in Ovariectomized Rats Nutrients doi: 10.3390/nu12072075 Authors: Hossam M. Abdallah Mohamed A. Farag Mardi M. Algandaby Mohammed Z. Nasrullah Ashraf B. Abdel-Naim Basma G. Eid Martin K. Safo Abdulrahman E. Koshak Azizah M. Malebari Lepidium sativum seeds are used traditionally to accelerate healing of bone fracture in addition to its culinary...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2074: Relevance of Essential Trace Elements in Nutrition and Drinking Water for Human Health and Autoimmune Disease Risk Nutrients doi: 10.3390/nu12072074 Authors: Daniela Cannas Eleonora Loi Matteo Serra Davide Firinu Paolo Valera Patrizia Zavattari Trace elements produce double-edged effects on the lives of animals and particularly of humans. On one hand, these elements represent potentially toxic agents; on the other hand, they are essentially...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2076: Adherence to the 2018 World Cancer Research Fund/American Institute for Cancer Research Recommendations and Breast Cancer in the SUN Project Nutrients doi: 10.3390/nu12072076 Authors: Rocio Barrios-Rodríguez Estefanía Toledo Miguel Angel Martinez-Gonzalez Inmaculada Aguilera-Buenosvinos Andrea Romanos-Nanclares José Juan Jiménez-Moleón A proportion of breast cancer cases are attributable to combined modifiable risk factors. The World Cancer...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2072: An Infant Formula with Partially Hydrolyzed Whey Protein Supports Adequate Growth and Is Safe and Well-Tolerated in Healthy, Term Infants: A Randomized, Double-Blind, Equivalence Trial Nutrients doi: 10.3390/nu12072072 Authors: Jean-Charles Picaud Barbara Pajek Malgorzata Arciszewska Izabela Tarczón Joaquin Escribano Rocio Porcel Thomas Adelt Elly Hassink Anneke Rijnierse Marieke Abrahamse-Berkeveld Bartosz Korczowski on behalf...
Mon Jul 13, 2020 03:00
Nutrients, Vol. 12, Pages 2071: A High-Protein Meal during a Night Shift Does Not Improve Postprandial Metabolic Response the Following Breakfast: A Randomized Crossover Study with Night Workers Nutrients doi: 10.3390/nu12072071 Authors: Nayara B. Cunha Catarina M. Silva Maria C. Mota Caio A. Lima Kely R. C. Teixeira Thulio M. Cunha Cibele A. Crispim The aim of this study was to compare the acute effect of a high-protein/moderate carbohydrate (HP-MCHO) versus low-protein/high-carbohydrate...
Mon Jul 13, 2020 03:00
Pathogens, Vol. 9, Pages 566: Biotic Factors Influence Microbiota of Nymph Ticks from Vegetation in Sydney, Australia Pathogens doi: 10.3390/pathogens9070566 Authors: Shona Chandra Jan Šlapeta Ticks are haematophagous ectoparasites of medical and veterinary significance due to their excellent vector capacity. Modern sequencing techniques enabled the rapid sequencing of bacterial pathogens and symbionts. This study’s aims were two-fold; to determine the nymph diversity in...
Mon Jul 13, 2020 03:00
Pathogens, Vol. 9, Pages 565: Mutational Frequencies of SARS-CoV-2 Genome during the Beginning Months of the Outbreak in USA Pathogens doi: 10.3390/pathogens9070565 Authors: Kaushal Gupta Goyal Khaiboullina Baranwal Verma : SARS-CoV-2 has spread very quickly from its first reported case on January 19th, 2020 in the United Stated of America, leading WHO to declare pandemic by March 11th, 2020. RNA viruses accumulate mutations following replication and passage in human...
Mon Jul 13, 2020 03:00
Pathogens, Vol. 9, Pages 567: Legionella Diversity and Spatiotemporal Variation in The Occurrence of Opportunistic Pathogens within a Large Building Water System Pathogens doi: 10.3390/pathogens9070567 Authors: Helen Y. Buse Brian J. Morris Vicente Gomez-Alvarez Jeffrey G. Szabo John S. Hall Understanding Legionella survival mechanisms within building water systems (BWSs) is challenging due to varying engineering, operational, and water quality characteristics unique to each...
Mon Jul 13, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 151: Safety of Repeated Administration of Parenteral Ketamine for Depression Pharmaceuticals doi: 10.3390/ph13070151 Authors: David Feifel David Dadiomov Kelly C. Lee The objective of this study was to investigate the safety of repeated parenteral ketamine for depression. An electronic survey inquiring about the frequency of adverse events was distributed to providers of parenteral ketamine for depression. In addition, the investigators conducted...
Mon Jul 13, 2020 03:00
Pharmaceutics, Vol. 12, Pages 659: Dynamic Colon Model (DCM): A Cine-MRI Informed Biorelevant In Vitro Model of the Human Proximal Large Intestine Characterized by Positron Imaging Techniques Pharmaceutics doi: 10.3390/pharmaceutics12070659 Authors: Konstantinos Stamatopoulos Sharad Karandikar Mark Goldstein Connor O’Farrell Luca Marciani Sarah Sulaiman Caroline L. Hoad Mark J. H. Simmons Hannah K. Batchelor This work used in vivo MRI images of human colon wall...
Mon Jul 13, 2020 03:00
Pharmacy, Vol. 8, Pages 119: The National Pharmaceutical Council: Endorsing the Construction of Imaginary Worlds in Health Technology Assessment Pharmacy doi: 10.3390/pharmacy8030119 Authors: Paul C Langley All too often, organizations embrace standards for health technology assessment that fail to meet those of normal science. A value assessment framework has been endorsed that is patently in the realm of pseudoscience. If a value assessment framework is to be accepted, then claims...
Mon Jul 13, 2020 03:00
Pharmacy, Vol. 8, Pages 118: The Use of a Decision Support System in Swedish Pharmacies to Identify Potential Drug-Related Problems—Effects of a National Intervention Focused on Reviewing Elderly Patients’ Prescriptions Pharmacy doi: 10.3390/pharmacy8030118 Authors: Tora Hammar Lina Hellström Lisa Ericson In pharmacies in Sweden, a clinical decision support system called Electronic Expert Support (EES) is available to analyse patients’ prescriptions for potential drug-related...
Mon Jul 13, 2020 03:00
Plants, Vol. 9, Pages 885: Genome-Wide Identification and Expression Profile Analysis of the Phospholipase C Gene Family in Wheat (Triticum aestivum L.) Plants doi: 10.3390/plants9070885 Authors: Xianguo Wang Yang Liu Zheng Li Xiang Gao Jian Dong Jiacheng Zhang Longlong Zhang Linda S. Thomashow David M. Weller Mingming Yang Phospholipid-hydrolyzing enzymes include members of the phospholipase C (PLC) family that play important roles in regulating plant growth...
Mon Jul 13, 2020 03:00
Plants, Vol. 9, Pages 884: Functional Analysis of Organic Acids on Different Oilseed Rape Species in Phytoremediation of Cadmium Pollution Plants doi: 10.3390/plants9070884 Authors: Shi Li Sixiu Le Xin Wang Jiuyuan Bai Rui Wang Yun Zhao Cadmium (Cd) pollution in soil is becoming increasingly serious due to anthropogenic activities, which not only poses a threat to the ecological environment, but also causes serious damage to human health via the biological chain. Consequently,...
Mon Jul 13, 2020 03:00
Plants, Vol. 9, Pages 880: Some Accessions of Amazonian Wild Rice (Oryza glumaepatula) Constitutively Form a Barrier to Radial Oxygen Loss along Adventitious Roots under Aerated Conditions Plants doi: 10.3390/plants9070880 Authors: Masato Ejiri Yuto Sawazaki Katsuhiro Shiono A barrier to radial oxygen loss (ROL), which reduces the loss of oxygen transported via the aerenchyma to the root tips, enables the roots of wetland plants to grow into anoxic/hypoxic waterlogged soil. However,...
Mon Jul 13, 2020 03:00
Plants, Vol. 9, Pages 883: Impacts of Phosphogypsum, Soluble Fertilizer and Lime Amendment of Acid Soils on the Bioavailability of Phosphorus and Sulphur Under Lucerne (Medicago sativa) Plants doi: 10.3390/plants9070883 Authors: Moussa Bouray Jim Moir Leo Condron Niklas Lehto Legumes play critical dual roles in grazed grassland ecosystems; providing nitrogen inputs and high-quality feed for grazing livestock. However, many species fail to persist in acidic, low fertility soils....
Mon Jul 13, 2020 03:00
Plants, Vol. 9, Pages 881: Acid Rain Increases Impact of Rice Blast on Crop Health via Inhibition of Resistance Enzymes Plants doi: 10.3390/plants9070881 Authors: Hong-Ru Li Hui-Min Xiang Jia-Wen Zhong Xiao-Qiao Ren Hui Wei Jia-En Zhang Qiu-Yuan Xu Ben-Liang Zhao Worldwide, rice blast (Pyricularia oryzae) causes more rice crop loss than other diseases. Acid rain has reduced crop yields globally for nearly a century. However, the effects of acid rain on rice-Pyricularia...
Mon Jul 1
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