Facial Plast SurgDOI: 10.1055/s-0040-1713791The tissues of the medial arm as a donor site for perforator flap design have several advantages. However, they are relatively underused with limited reports, partly due to unreliable perforator anatomy. Therefore, we aimed to review our preliminary experience using indocyanine green (ICG) angiography to design and elevate preexpanded pedicled brachial artery perforator (BAP) flaps for regional reconstruction. All patients underwent soft tissue reconstructions...
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Abstract Nemonoxacin is a novel non-fluorinated quinolone. The effect of nemonoxacin on modulation of host immune response is not known. We sought to determine whether nemonoxacin has immunoprotective effects on lipopolysaccharide (LPS)-induced mouse sepsis model. Therefore, mice were challenged with lethal dose LPS (12.5 mg/kg) only or LPS with multi-dose nemonoxacin (40 mg/kg q12h) by intraperitoneal injection, and the results showed...
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Shailendra S Naik, Ilavarasi Vanidassane, Ekta Dhamija, Atul SharmaIndian Journal of Radiology and Imaging 2020 30(2):214-217 5-Fluorouracil (5-FU), a commonly used antimetabolite and antineoplastic agent, has been approved for the treatment of various cancers. It is associated with systemic side-effects such as gastrointestinal problems, neutropenia. 5-FU-related encephalopathy is very rarely reported. Imaging with computed tomography (CT) and magnetic resonance imaging (MRI) plays a key role...
Anith Chacko, Schadie Vedajallam, Savvas Andronikou, Ewan Simpson, Ngoc Jade ThaiIndian Journal of Radiology and Imaging 2020 30(2):111-115 Background: Using text reports to communicate bilateral, symmetric, and zonal cortical brain atrophy in children with term hypoxic ischemic injury (HII) to parents and legal professionals contesting compensation rights can be difficult. Using standard cross-sectional images for explaining bilateral, regional brain imaging to laypeople is also challenging....
Alexis Morales, Guillermo Aguilera, Dieter KrauseIndian Journal of Radiology and Imaging 2020 30(2):244-245
Sivaramalingam Geethapriya, Jayaraj Govindaraj, Bagyam Raghavan, Banupriya Ramakrishnan, Rasheed Arafath, Sathyashree Vishwanathan, Murali KrishnaIndian Journal of Radiology and Imaging 2020 30(2):116-125 Schwannomas are peripheral nerve sheath tumours arising from cranial, spinal or peripheral nerves. Most of the schwannomas are benign with the rare possibility of malignant transformation. Cranial nerve schwannomas can be seen along the course of any cranial nerve in the intracranial region...
Richa D Jain, Lokesh Bathala, HK Anuradha, Sudhir K Kale, Guruprasad S Pujar, Man M Mehndiratta, Leo H VisserIndian Journal of Radiology and Imaging 2020 30(2):229-232 Carpal tunnel syndrome is a common peripheral nerve entrapment neuropathy caused due to compression of the median nerve at the level of the wrist joint. Bifid median nerve associated with a persistent median artery is a rare entity and in itself asymptomatic anatomical variant. However, distension of the persistent median artery...
Reddy RavikanthIndian Journal of Radiology and Imaging 2020 30(2):126-138 Introduction: Magnetic resonance imaging (MRI) has become the cornerstone for pretreatment evaluation of carcinoma tongue and provides accurate information regarding the extent of the lesion and depth of invasion that helps the clinician to optimize treatment strategy. Aim of the study is to correlate MRI and histopathological findings, to evaluate the role of MRI in loco-regional tumor node metastasis (TNM) staging, and...
Anirudh KohliIndian Journal of Radiology and Imaging 2020 30(2):105-110
Abhinav C Bhagat, Jyoti Kumar, Anju Garg, Anjali Prakash, Ravi Meher, Shivali AryaIndian Journal of Radiology and Imaging 2020 30(2):139-148 Malformations of the inner ear are an important cause of congenital deaf-mutism. Arrest in embryologic development of inner ear during various stages gives rise to the variety of malformations encountered. Current treatment options include hearing aids, cochlear implants, and auditory brainstem implants (ABI). With the advent of cochlear implant surgery...
Nithisha Thatikonda, Juan Gomez, Eduardo Gonazalez ToledoIndian Journal of Radiology and Imaging 2020 30(2):222-224 A 9-year-old boy was admitted to our institution with acute onset of bilateral blurry vision. Physical examination revealed bilateral papilledema. Cerebrospinal fluid analysis and comprehensive metabolic panel were normal. Magnetic resonance imaging (MRI) of the brain showed extensive bilateral optic nerve inflammation with post-contrast gadolinium enhancement on T1-weighted sequence....
Navita Aggarwal, GL SharmaIndian Journal of Radiology and Imaging 2020 30(2):149-155 Background: Fetal biometry, with the help of ultrasonography (USG) provides the most reliable and important information about fetal growth and well-being. Frequently used parameters for fetal measurements by this method are the biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), and femur length (FL). These fetal dimensions depend upon the racial demographic characteristics, nutrition,...
Vaibhav Gulati, Arif Mirza, Parveen GulatiIndian Journal of Radiology and Imaging 2020 30(2):237-239 Unilateral or bilateral agenesis of the parotid gland is an uncommon condition with unclear aetiology. Only 22 cases of unilateral salivary agenesis have been reported excluding the present case. We present a case of a 4-year-old female child who presented with complaints of slight discoloration of her tongue and was referred for MRI to rule out any vascular malformation. Imaging revealed a complete...
Sujitkumar Hiwale, Celine FirtionIndian Journal of Radiology and Imaging 2020 30(2):156-162 Context: The primary objective of this study was to examine the impact of maternal age, parity, gestational age, fetal gender, gestational diabetes mellitus, and pregnancy-induced hypertension on the accuracy of ultrasonography-based fetal weight estimation. The secondary objective was to find the impact of a formula selection on the accuracy of fetal weight estimation. Subjects and Methods: The inclusion...
Esther L Pachuau, Isak LallawmkimaIndian Journal of Radiology and Imaging 2020 30(2):247-248
Zafar Neyaz, Zia Hashim, Sunil Kumar, Alok Nath, Ajmal Khan, Namita MohindroIndian Journal of Radiology and Imaging 2020 30(2):163-169 Context: Few studies have been done for correlating asthma severity, IgE level, and spirometry results with high-resolution computed tomographic (HRCT) findings in allergic bronchopulmonary aspergillosis (ABPA). Aims: This prospective observational study was conducted to correlate asthma severity, IgE level, and spirometry results with HRCT findings in ABPA. Settings...
Kunal B Gala, Nitin S Shetty, Paresh Patel, Suyash S KulkarniIndian Journal of Radiology and Imaging 2020 30(2):206-213 Minimally invasive techniques such as Image guided thermal ablation are now widely used in the treatment of tumors. Microwave ablation (MWA) is one of the newer modality of thermal ablation and has proven its safety and efficacy in the management of the tumors amenable for ablation for primary and metastatic diseases. It is used in the treatment of primary and secondary liver...
Sunita V Kale, Shah AlamIndian Journal of Radiology and Imaging 2020 30(2):170-176 Background: It is imperative to establish normative ranges of aortic diameter to diagnose various aortic pathologies. There have been very few studies establishing the normal aortic diameter on cross-sectional imaging, and none pertaining to the Indian pediatric population. The objective of this study was, therefore, to establish the normal effective diameter of thoracic aorta at multiple levels using computed...
S Senthil Raj Kumar, S Shanmuga Jayanthan, G RupeshIndian Journal of Radiology and Imaging 2020 30(2):218-221 Dentate nucleus, the largest deep nucleus of the cerebellum, is affected by numerous conditions, including leukodystrophies, toxins, drugs, infections, and various metabolic and inflammatory conditions. This case report is a drug-induced cerebellitis, caused by isoniazid (INH), characterized in magnetic resonance imaging (MRI) as bilateral dentate nuclei hyperintensity. Isoniazid, an...
Amit A Deshpande, SH Chandrashekhara, Arun SharmaIndian Journal of Radiology and Imaging 2020 30(2):177-180 The superior-inferior ventricle is a rare anomaly with the unknown incidence owing to less number of reported cases. However, one of the studies has reported this incidence to be <0.1% of all congenital heart diseases. This has a characteristic imaging appearance with horizontal interventricular septum. Most of the previous reports of superior-inferior ventricles have been described...
Anju MathewIndian Journal of Radiology and Imaging 2020 30(2):225-228 Granular cell ameloblastoma is a rare condition, accounting for 3.5% of all ameloblastoma cases that shows marked transformation in the cytoplasm of tumor cells, which are usually stellate reticulum-like cells. The transformed cells possess very coarse, granular eosinophilic cytoplasm. Granular cell ameloblastoma is aggressive in nature with a marked propensity for recurrence and can progress to metastasis. This article discusses...
Patrick M Foye, Woon T K Jason, Kevin Y Zheng, Kenneth K LeongIndian Journal of Radiology and Imaging 2020 30(2):181-183 Context: Focal sympathetic nerve blocks of the ganglion impar are often effective treatments for coccydynia (coccyx pain) and other pelvic pain syndromes. These injections are generally performed under contrast-enhanced fluoroscopic guidance. Vascular uptake may potentially occur during the injection and vascular uptake rates have been reported for other spinal injections,...
Surbhi Singh, Akhil TanwarIndian Journal of Radiology and Imaging 2020 30(2):233-236 Pseudotumor deltoideus refers to focal cortical irregularity and thickening at the deltoid insertion. It is benign in nature with a possible role as a tumor stimulator and possesses various anatomic variations. A well-defined area of cortical irregularity and radiological lucency at the deltoid insertion are uncommon radiological findings that pose a diagnostic dilemma. In this case report, we demonstrate a 45-year-old...
Peeyush K Dhagat, Megha Jain, Afaq FarooqIndian Journal of Radiology and Imaging 2020 30(2):184-189 Background: Soft tissue vascular malformations are not uncommonly encountered in clinical practice and are often mistaken for other pathologies. Vascular anomalies are divided into vascular tumors and malformations. Vascular malformations progressively increase in size with increasing age and are classified into low-flow (venous, lymphatic, veno-lymphatic, capillary and capillary venous) and high-flow...
Divya B Desai, Neeti P Mathur, Arnab MarikIndian Journal of Radiology and Imaging 2020 30(2):240-243 Absent pulmonary valve syndrome (APVS) is a rare congenital cardiac malformation characterized by absent, dysplastic, or rudimentary pulmonary valve leaflets in association with other cardiac anomalies. It has an incidence of 3-6% in cases of tetralogy of Fallot (TOF) and 0.2-0.4% of live-born infants with congenital heart disease (CHD). Absent pulmonary valve leads to dilated main pulmonary artery;...
Anupam Sahu, H Vikas, Nishant SharmaIndian Journal of Radiology and Imaging 2020 30(2):190-194 Background: Life cycle costing (LCC) is an excellent decision-making tool that can assist a hospital administrator in seeking more cost-effective decisions to select the best course of action. LCC can be defined as “an economic assessment of competing design alternatives, considering all significant costs of ownership over the economic life of each alternative, expressed in equivalent rupees. Aim: To...
Ayush Jain, Shilpa SankheIndian Journal of Radiology and Imaging 2020 30(2):245-247
M Sarthak Swarup, Swati Gupta, Sapna Singh, Anjali Prakash, Anurag Mehndiratta, Anju GargIndian Journal of Radiology and Imaging 2020 30(2):195-205 Phakomatoses or Neurocutaneous syndromes are a heterogeneous group of disorders and have variable inheritance pattern. Currently, more than 30 entities are included in this group. These disorders primarily affect the central nervous system; however, skin, viscera, and other connective tissues can also be involved with variable clinical presentation....
Ankit Balani, Chinky ChaturIndian Journal of Radiology and Imaging 2020 30(2):249-250
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Emerging data indicates that extracellular traps (ETs), structures formed by various immune cell types, may contribute to the pathology of noninfectious inflammatory diseases. Histone hypercitrullination is an...
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Background. The Baveno VI criteria based on platelet count and liver stiffness, measured by transient elastography (TE), have been proposed to rule out high-risk varices (HRV) defined as medium or large-sized varices or the presence of high-risk stigmata (cherry red spots and red wale marks). However, TE is not available in all hospitals. Recently, the Rete Sicilia Selezione Terapia hepatitis C virus (RESIST-HCV) criteria recommended that cirrhotic patients with a and could avoid esophagogastroduodenoscopy...
Diabetic nephropathy (DN), one of the most common and severe microvascular complications of diabetes mellitus (DM), is an important risk factor for DM patient’s death. Nowadays, DN has become the leading cause of end-stage renal disease (ESRD) in most countries without effective therapeutic methods. Recently, the renoprotective effects mediated by vitamin D (VD) and vitamin D receptor (VDR) have been evidenced. VD, a kind of steroid with the active form 1,25(OH)2D3, has been known for the crucial...
Background. Apoptosis, a major form of programmed cell death, plays a vital role in regulating tissue development and maintenance of homeostasis in eukaryotes. Apoptosis can occur via a death receptor-dependent extrinsic or a mitochondrial-dependent intrinsic pathway and can be induced by various chemotherapeutic agents. In this study, the anticancer activity of Saussurea costus and its mode of intervention in human cancer cells of breast, colon, and liver were investigated. Results. In this study,...
Low plasma triiodothyronine (T3) concentration indicates nonthyroidal illness syndrome (NTIS), which might be associated with a poor outcome in patients in the intensive care unit (ICU). This study evaluated the relationship between NTIS and prognostic indicators in patients admitted to the ICU and examined the fT3 cut-off points that could be associated with 28-day mortality. This prospective observational study included patients admitted to the ICU of The Third Hospital of Hebei Medical University...
Herein, the structural effect of autologous platelet-rich plasma (PRP) on posttraumatic skeletal muscle regeneration in rats with chronic hyperglycemia (CH) was tested. 130 white laboratory male rats divided into four groups (I—control; II—rats with CH; III—rats with CH and PRP treatment; and IV—rats for CH confirmation) were used for the experiment. CH was simulated by streptozotocin and nicotinic acid administration. Triceps surae muscle injury was reproduced by transverse linear incision. Autologous...
Cancer stem cells (CSCs) are subsets of cells with the ability of self-renewal and differentiation in neoplasm, which are considered to be related to tumor heterogeneity. It has been reported that CSCs act on tumorigenesis and tumor biology of triple-negative breast cancer (TNBC). However, the key genes that cause TNBC showing stem cell characteristics are still unclear. We combined the RNA sequencing (RNA-seq) data from The Cancer Genome Atlas (TCGA) database and mRNA expression-based stemness index...
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Oncogenesis, Published online: 13 July 2020; doi:10.1038/s41389-020-00251-5Suppressing DRP1-mediated mitochondrial fission and mitophagy increases mitochondrial apoptosis of hepatocellular carcinoma cells in the setting of hypoxia
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In critically ill patients, the use of high tigecycline dosages (HD TGC) (200 mg/day) has been recently increasing but few pharmacokinetic/pharmacodynamic (PK/PD) data are available. We designed a prospective ...
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