Does thiamine protect the brain from iron overload and alcohol-related dementia? Alzheimers Dement. 2020 Aug 18;: Authors: Listabarth S, König D, Vyssoki B, Hametner S Abstract Alcohol-related dementia (ARD) is a common and severe co-morbidity in alcohol use disorder (AUD). We propose brain iron overload (BIO) to be an important and previously neglected pathogenic process, accelerating cognitive decline in AUD. Furthermore, we suggest thiamine,...
Wed Aug 19, 2020 13:29
Related Articles Choline transporter-like 1 deficiency causes a new type of childhood-onset neurodegeneration. Brain. 2020 01 01;143(1):94-111 Authors: Fagerberg CR, Taylor A, Distelmaier F, Schrøder HD, Kibæk M, Wieczorek D, Tarnopolsky M, Brady L, Larsen MJ, Jamra RA, Seibt A, Hejbøl EK, Gade E, Markovic L, Klee D, Nagy P, Rouse N, Agarwal P, Dolinsky VW, Bakovic M Abstract Cerebral choline metabolism is crucial for normal brain function,...
Wed Aug 19, 2020 13:29
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 19, 2020 17:36
35 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 19, 2020 13:39
102 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 19, 2020 17:20
102 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 19, 2020 13:20
2787 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 19, 2020 16:13
There are three solutions to this maze. Can you solve them all? (Glenn Orzepowski/)We know you are bored at home right now—we are too. Here are some puzzles and brainteasers to challenge your family and friends with, either in person or over video chat.Humans have meandered through mazes for thousands of years, whether they be ancient Egyptian labyrinths, a Minotaur’s lair, passageways carved in cornfields, or horrifying hedges in Stephen King’s The Shining. Each puzzle’s objective is simple: Navigate...
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The EPA finalized the rule change this week after foreshadowing it for several months. (Environmental Protection Agency/)Jeremy Deaton writes for Nexus Media, a nonprofit climate change news service. You can follow him @deaton_jeremy. This story was published in partnership with Nexus Media.This year, levels of methane, a powerful heat-trapping gas, hit an all-time high, driven in large part by pollution leaking from gas pipelines and drilling sites. Plugging these leaks is cheap, has enormous upsides...
Wed Aug 19, 2020 23:00
The Pappy Lane shipwreck, as seen from above. (John McCord/)Thousands of vessels are submerged in the waters off the coast of North Carolina. The Outer Banks, with its strong currents and storms that create treacherous conditions for ships, is nicknamed “The Graveyard of the Atlantic.” However, many of these wrecks have taken on new duties by providing valuable habitat for fish and other marine animals—as well as hordes of microscopic lifeforms. When scientists recently investigated the microbial...
Wed Aug 19, 2020 21:00
If you're making one of each kind of wipe, make sure you label them. You really don't want a 70% alcohol solution on your baby's skin. (Sandra Gutierrez G. /)Follow all of PopSci’s COVID-19 coverage here, including tips on cleaning groceries, ways to tell if your symptoms are just allergies, and a tutorial on making your own mask.Shortages have been a big side effect of the pandemic. They started with a whole range of household cleaning products flying off the shelves in March, and have continued...
Wed Aug 19, 2020 19:00
This F-16 in Florida is being flown by a real human. (US Air Force / Tech. Sgt. John Raven/)Fighter jets need humans to fly them, but someday, that could change. This week, the Defense Advanced Research Project Agency—better known as DARPA—is hosting a virtual Top Gun-style competition in which various artificial intelligence algorithms fly simulated jets in digital dogfights. No actual planes are in the air, but the goal is to see which AI agent can provide the most formidable fighter. The event...
Wed Aug 19, 2020 17:00
Tasty treat for a healthy life. (Kelly Sikkema via Unsplash/)Protein shakes are not just used by serious athletes and bodybuilders. They are quick and easy additions to your diet and can replace meals packed with protein, vitamins, and probiotics—or they can act as a supplement for after your workout to help your muscles recover and strengthen. For meals on the go you can buy your shakes pre-mixed and individually packaged for a quick grab and go snack. Or, you can purchase powders that can be blended...
Wed Aug 19, 2020 15:50
Work or play with minimal interruption. (ConvertKit via Unsplash/)Dependable WiFi access is crucial when working or unwinding at home. If your signal constantly drops when presenting in meetings or leaves you with unexpected cliffhangers watching shows, you can expand the coverage area of your WiFi network with an extender. Improve the strength and range of your connection with these affordable and efficient WiFi extenders.Sleek and speedy. (Amazon/)This compact, universally adaptable TP-Link RE220...
Wed Aug 19, 2020 16:18
Now you just need a podcast idea. ( Jonathan Farber via Unsplash/)It seems like someone starts a podcast every day. And that’s because they do. Podcasts are fairly simple to start but challenging to maintain at a high quality. If you sound like you are recording in the closet on an iPhone 6 people probably won’t hang around for your witty banter. Start on the right foot with a decent mixer/recorder, microphones, sound proofing and headphones and you’ll get that crisp, engaging sound all your favorite...
Wed Aug 19, 2020 15:40
While some options eliminate COVID-19 concerns, they still may be worrisome for other reasons. (Julia M Cameron from Pexels/)Follow all of PopSci’s COVID-19 coverage here, including breakdowns of the safest swimming options, safest dining options, and a tutorial on safest long-distance travel options.School is back in session for many students across the country, which means tough decisions surrounding education are falling on the shoulders of teachers, school districts, and parent-guardians. With...
Wed Aug 19, 2020 15:13
Evaluation of variant calling tools for large plant genome re-sequencing. BMC Bioinformatics. 2020 Aug 17;21(1):360 Authors: Yao Z, You FM, N'Diaye A, Knox RE, McCartney C, Hiebert CW, Pozniak C, Xu W Abstract BACKGROUND: Discovering single nucleotide polymorphisms (SNPs) from agriculture crop genome sequences has been a widely used strategy for developing genetic markers for several applications including marker-assisted breeding, population...
Wed Aug 19, 2020 14:32
Health professionals learning qualitative research in their workplace: a focused ethnography. BMC Med Educ. 2020 Aug 17;20(1):269 Authors: Ghirotto L, De Panfilis L, Di Leo S Abstract BACKGROUND: The interest for qualitative research methodology has expanded beyond theoretical academic research on medical education, gathering interest from all healthcare professionals. Qualitative research has potentials in exploring the social, emotional,...
Wed Aug 19, 2020 15:29
Theoretically designed interventions for colorectal cancer prevention: a case of the health belief model. BMC Med Educ. 2020 Aug 17;20(1):270 Authors: Rakhshanderou S, Maghsoudloo M, Safari-Moradabadi A, Ghaffari M Abstract BACKGROUND: According to the WHO, most chronic diseases, including cancer, can be prevented by identifying their risk factors such as unhealthy diet, smoking and physical inactivity. This research examined the effectiveness...
Wed Aug 19, 2020 15:29
Assessing the benefits and usefulness of Schwartz Centre rounds in second-year medical students using clinical educator-facilitated group work session: not just "a facilitated moan"! BMC Med Educ. 2020 Aug 17;20(1):271 Authors: Smith J, Stewart MG, Foggin E, Mathews S, Harris J, Thomas P, Cooney A, Stocker CJ Abstract BACKGROUND: An experiential curriculum exposing medical students to the clinic early has many benefits but comes with the emotional...
Wed Aug 19, 2020 15:29
Bibliometric analysis of global scientific literature on vaccine hesitancy in peer-reviewed journals (1990-2019). BMC Public Health. 2020 Aug 17;20(1):1252 Authors: Sweileh WM Abstract BACKGROUND: Vaccine hesitancy is a growing threat to national and global health security. The current study was undertaken to provide insights into the global scientific literature on vaccine hesitancy in peer-reviewed journals. METHOD: The current study...
Wed Aug 19, 2020 16:16
Space-time analysis of ovarian cancer mortality rates by age groups in spanish provinces (1989-2015). BMC Public Health. 2020 Aug 17;20(1):1244 Authors: Trandafir PC, Adin A, Ugarte MD Abstract BACKGROUND: Ovarian cancer is a silent and largely asymptomatic cancer, leading to late diagnosis and worse prognosis. The late-stage detection and low survival rates, makes the study of the space-time evolution of ovarian cancer particularly relevant....
Wed Aug 19, 2020 16:16
ART use and associated factors among HIV positive caregivers of orphans and vulnerable children in Tanzania. BMC Public Health. 2020 Aug 17;20(1):1251 Authors: Exavery A, Charles J, Barankena A, Kuhlik E, Mubyazi GM, Tani K, Ally A, Minja E, Koler A, Kikoyo L, Jere E Abstract BACKGROUND: Utilization of antiretroviral therapy (ART) is crucial for better health outcomes among people living with the human immunodeficiency virus (PLHIV). Nearly...
Wed Aug 19, 2020 16:16
Changes in rural older adults' sedentary and physically-active behaviors between a non-snowfall and a snowfall season: compositional analysis from the NEIGE study. BMC Public Health. 2020 Aug 17;20(1):1248 Authors: Amagasa S, Inoue S, Murayama H, Fujiwara T, Kikuchi H, Fukushima N, Machida M, Chastin S, Owen N, Shobugawa Y Abstract BACKGROUND: Levels of physical activity change throughout the year. However, little is known to what extent activity...
Wed Aug 19, 2020 16:16
Predictors of infant-survival practices among mothers attending paediatric clinics in Ijebu-Ode, Ogun State, Nigeria. BMC Public Health. 2020 Aug 17;20(1):1245 Authors: Sokefun EE, Atulomah NO Abstract BACKGROUND: Despite concerted global efforts towards achieving infant-survival, infant mortality lingers as a problem in developing countries. Environmental and personal-level factors are assumed to account for this situation. This study was...
Wed Aug 19, 2020 16:16
A systematic review of studies that measure parental vaccine attitudes and beliefs in childhood vaccination. BMC Public Health. 2020 Aug 17;20(1):1253 Authors: Dyda A, King C, Dey A, Leask J, Dunn AG Abstract BACKGROUND: Acceptance of vaccines is an important predictor of vaccine uptake. This has public health implications as those who are not vaccinated are at a higher risk of infection from vaccine preventable diseases. We aimed to examine...
Wed Aug 19, 2020 16:16
Effectiveness of martial arts exercise on anthropometric and body composition parameters of overweight and obese subjects: a systematic review and meta-analysis. BMC Public Health. 2020 Aug 17;20(1):1246 Authors: de Souza F, Lanzendorf FN, de Souza MMM, Schuelter-Trevisol F, Trevisol DJ Abstract BACKGROUND: Obesity is considered a top public health concern, and its prevalence is growing every day. Thus, interventions to address this problem...
Wed Aug 19, 2020 16:16
"Like a ticking time bomb": the persistence of trauma in the HIV diagnosis experience among black men who have sex with men in New York City. BMC Public Health. 2020 Aug 17;20(1):1247 Authors: Mgbako O, Benoit E, Iyengar NS, Kuhner C, Brinker D, Duncan DT Abstract BACKGROUND: Black men who have sex with men (MSM) are disproportionately affected by HIV compared to almost every other demographic group in the country and have worse outcomes along...
Wed Aug 19, 2020 16:16
Knowledge, attitudes and practices of young adults towards HIV prevention: an analysis of baseline data from a community-based HIV prevention intervention study in two high HIV burden districts, South Africa. BMC Public Health. 2020 Aug 17;20(1):1249 Authors: Shamu S, Khupakonke S, Farirai T, Slabbert J, Chidarikire T, Guloba G, Nkhwashu N Abstract BACKGROUND: With an HIV incidence of 1.00 skewed against women (1.51), adolescents in South Africa...
Wed Aug 19, 2020 16:16
Risk factors affecting treatment outcomes for pulmonary tuberculosis in Finland 2007-2014: a national cohort study. BMC Public Health. 2020 Aug 17;20(1):1250 Authors: Korhonen V, Lyytikäinen O, Ollgren J, Soini H, Vasankari T, Ruutu P Abstract BACKGROUND: Major transition in tuberculosis (TB) epidemiology is taking place in many European countries including Finland. Monitoring treatment outcome of TB cases is important for identifying gaps...
Wed Aug 19, 2020 16:16
Allicin Overcomes Hypoxia Mediated Cisplatin Resistance in Lung Cancer Cells through ROS Mediated Cell Death Pathway and by Suppressing Hypoxia Inducible Factors. Cell Physiol Biochem. 2020 Aug 19;54(4):748-766 Authors: Pandey N, Tyagi G, Kaur P, Pradhan S, Rajam MV, Srivastava T Abstract BACKGROUND/AIMS: The hypoxic microenvironment in NSCLC has been widely accepted as a contributor to both therapeutic resistance and tumor progression. In...
Wed Aug 19, 2020 18:18
Effects of Probiotics in Conditions or Infections Similar to COVID-19 on Health Outcomes: An Evidence Analysis Center Scoping Review. J Acad Nutr Diet. 2020 Jul 20;: Authors: Rozga M, Cheng FW, Handu D Abstract Probiotics have been suggested as a potential intervention for improving outcomes, particularly ventilatory-associated pneumonia, in patients infected with coronavirus disease 2019 (COVID-19). However, with the rapid development of the...
Wed Aug 19, 2020 15:06
Dietary Polyphenol Intake in US Adults and 10-Year Trends: 2007-2016. J Acad Nutr Diet. 2020 Aug 14;: Authors: Huang Q, Braffett BH, Simmens SJ, Young HA, Ogden CL Abstract BACKGROUND: Polyphenols are a class of phytochemicals that have antioxidant, anti-inflammatory, anticancer, and antiviral properties. Previous research suggests that dietary polyphenol intake is protective against major chronic diseases. To our knowledge, no data on polyphenol...
Wed Aug 19, 2020 15:06
microRNA-495 alleviates endothelial cell inflammatory injury in coronary heart disease via blockade of the NF-κB pathway by targeting RALB. J Cell Physiol. 2020 Aug 18;: Authors: Lv FF, Lian Z, Yan LQ, Wang G, Li Z Abstract Accounting for high mortality worldwide, coronary heart disease (CHD) is a severe disease characterized by abnormal intercellular communication, and microRNAs (miRNAs or miRs) have been shown to be involved in this process....
Wed Aug 19, 2020 16:24
Modulation of BAG3 expression in human normal urothelial cells by Diuron. J Cell Physiol. 2020 Aug 18;: Authors: Eletto D, Reppucci F, Ronga A, Altieri V, Brongo S, Martinelli R, De Marco M, Marzullo L Abstract Diuron [3-(3,4-dichlorophenyl)-1,1-dimethylurea] is a substituted urea herbicide, carcinogenic for the rat urinary bladder. It has been hypothesized that Diuron cytotoxicity, resulting in regenerative proliferation, leads to urothelial...
Wed Aug 19, 2020 16:24
PM2.5 facilitates IL-6 production in human osteoarthritis synovial fibroblasts via ASK1 activation. J Cell Physiol. 2020 Aug 17;: Authors: Liu JF, Chi MC, Lin CY, Lee CW, Chang TM, Han CK, Huang YL, Fong YC, Chen HT, Tang CH Abstract Osteoarthritis (OA) is a progressive degenerative joint disorder characterized by synovial inflammation. Interleukin-6 (IL-6) is a key proinflammatory cytokine in OA progression. Particulate matter 2.5 (PM2.5)...
Wed Aug 19, 2020 16:24
Astaxanthin-Shifted Gut Microbiota Is Associated with Inflammation and Metabolic Homeostasis in Mice. J Nutr. 2020 Aug 18;: Authors: Wu L, Lyu Y, Srinivasagan R, Wu J, Ojo B, Tang M, El-Rassi GD, Metzinger K, Smith BJ, Lucas EA, Clarke SL, Chowanadisai W, Shen X, He H, Conway T, von Lintig J, Lin D Abstract BACKGROUND: Astaxanthin is a red lipophilic carotenoid that is often undetectable in human plasma due to the limited supply in typical...
Wed Aug 19, 2020 13:24
Synaptic competition: 'to be or not to be' the calyx of Held? J Physiol. 2020 Aug 18;: Authors: Tawfik B, Wang LY PMID: 32809213 [PubMed - as supplied by publisher]
Wed Aug 19, 2020 13:15
Πρόσφατη μελέτη από την Ιατρική Σχολή του Πανεπιστημίου της Καλιφόρνια στο Σαν Ντιέγκο διαπίστωσε την ευεργετική επίδραση του ύπνου στη διαδικασία της μάθησης καθ’ όλη τη διάρκεια της ζωή μας αλλά και στη θωράκιση της μνήμης. Για τη διεξαγωγή των συμπερασμάτων τους, οι ερευνητές αξιοποίησαν υπολογιστικά μοντέλα προσομοίωσης διαφορετικών καταστάσεων του εγκεφάλου όπως όταν κοιμόμαστε ή είμαστε ξύπνιοι, ώστε να διερευνήσουν πώς ο ύπνος ενοποιεί τις πρόσφατα κωδικοποιημένες αναμνήσεις και αποτρέπει...
Wed Aug 19, 2020 12:41
Χρησιμοποιώντας γονιδιακή ανάλυση, οι επιστήμονες από το Πανεπιστήμιο της Georgia, στις ΗΠΑ, που δημοσίευσαν τη σχετική μελέτη στο Microbial Biotechnology, βρήκαν έναν ισχυρό συσχετισμό ανάμεσα στην αντίσταση στα αντιβιοτικά και τη ρύπανση του περιβάλλοντος από βαρέα μέταλλα. Όπως δείχνουν τα ευρήματα του Jesse C. Thomas IV, τα εδάφη που εξετάστηκαν και είχαν μολυνθεί με βαρέα μέταλλα, είχαν υψηλότερο επίπεδο συγκεκριμένων βακτηριακών ξενιστών που συνοδεύονταν από γονίδια ανθεκτικά στα αντιβιοτικά....
Wed Aug 19, 2020 09:40
Ο κίνδυνος αποβολής αυξάνεται προοδευτικά έως 8% για κάθε εβδομάδα κατά την οποία η έγκυος καταναλώνει αλκοόλ κατά τις πρώτες πέντε έως δέκα εβδομάδες της κύησης, βάσει εκτεταμένης ανάλυσης ερευνητών του Ιατρικού Κέντρου του Πανεπιστημίου Βάντερμπιλτ στις ΗΠΑ. Οι ερευνητές παρακολούθησαν 5.353 γυναίκες από μητροπολιτικές περιοχές του Τενεσί, της Βόρειας Καρολίνας και το Τέξας κατά το πρώτο τρίμηνο κύησης, εξετάζοντας πώς η αναφερόμενη εκ μέρους τους κατανάλωση αλκοόλ συσχετίζεται με τον κίνδυνο...
Wed Aug 19, 2020 09:02
Μία μελέτη που δημοσιεύθηκε στο Transboundary and Emerging Diseases επικεντρώθηκε στην περιοχή του Σίδνεϊ της Αυστραλίας κατά τη διάρκεια του πρώτου επιδημικού σταδίου της COVID-19 και βρήκε ένα συσχετισμό ανάμεσα στη χαμηλή υγρασία και την αύξηση της μεταδοτικότητας του κορωνοϊού στην κοινότητα. Η έρευνα, με επικεφαλής τον καθηγητής Michael Ward, Επιδημιολόγο στο Πανεπιστήμιο του Σίδνεϊ και δύο ερευνητές από Πανεπιστήμιο της Κίνας, είναι η δεύτερη που εξετάζει τη σχέση ανάμεσα στις καιρικές συνθήκες...
Wed Aug 19, 2020 08:48
Σύμφωνα με πρόσφατη μελέτη, που δημοσιεύτηκε στο Journal of Transport and Health, ο λόγος που περπατά κάποιος αποδίδει οφέλη διαφορετικού μεγέθους στην υγεία του και αντιστοιχεί σε διαφορετική αξιολόγησή της από τον ίδιο. Έτσι, όσοι περπατούσαν από το σπίτι με σκοπό την έγκαιρη προσέλευση στη δουλειά ή αγορές στο μανάβικο, ανέφεραν καλύτερα επίπεδα υγείας από εκέινους που περπατούσαν κυρίως για αναψυχή. Όπως εξήγησε η Gulsah Akar, αναπληρώτρια καθηγήτρια Πολεοδοµίας – Χωροταξίας στη Σχολή Αρχιτεκτονικής...
Wed Aug 19, 2020 08:34
Ερευνητές στο Πανεπιστήμιο Pavol Jozef Šafárik στο Κόσιτσε της Σλοβακίας εντόπισαν ομάδα φθοριζόντων μορίων που είναι εύκολα ανιχνεύσιμα στα ούρα και τα οποία συσχετίζονται με την εξέλιξη του μελανώματος, γεγονός που γεννά νέας δυνατότητες για την παρακολούθηση της πιο επιθετικής και απειλητικής μορφής καρκίνου του δέρματος. Τα ευρήματά τους δημοσιεύονται στο Open Chemistry του επιστημονικού εκδοτικού οίκου De Gruyter. Επί του παρόντος απαιτείται βιοψία για τη διάγνωση του μελανώματος και την παρακολούθηση...
Wed Aug 19, 2020 08:19
Καθώς η επιστημονική κοινότητα συνεχίζει να μάχεται ενάντια στον κορωνοϊό, νεότερα δεδομένα έρχονται να αναδείξουν τη σχέση του με τις καρδιαγγειακές συννοσηρότητες και την παχυσαρκία και πως οι δύο αυτές οι χρόνιες καταταστάσεις συνεπάγονται αυξημένο κίνδυνο θανάτου. Συγκεκριμένα, οι ασθενείς με καρδιαγγειακές συννοσηρότητες ή παράγοντες καρδιαγγειακού κινδύνου διατρέχουν υψηλότερο κίνδυνο να εμφανίσουν επιπλοκές κατά τη διάρκεια της νοσηλείας και είναι πιο πιθανό να πεθάνουν από τη νόσο COVID-19,...
Wed Aug 19, 2020 07:57
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