Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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! # Ola via Alexandros G.Sfakianakis on Inoreader

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Τετάρτη 19 Αυγούστου 2020

 


The Diversity of Midgut Bacteria among Wild-Caught Phlebotomus argentipes (Psychodidae: Phlebotominae), the Vector of Leishmaniasis in Sri Lanka
Phlebotomus argentipes is the main suspected vector for leishmaniasis in Sri Lanka. Investigations on the presence of aerobic bacteria in the gut of sand flies which evidence a potential approach to control leishmaniasis transmission through a paratransgenic strategy are still not available for the local sand fly populations. Field-caught unfed female sand flies collected from three selected Medical Officer of Health (MOH) areas (Polpithigama, Maho, and Galgamuwa) in Kurunegala District, Sri Lanka...
BioMed Research International
Wed Aug 19, 2020 17:35
Construction of a MicroRNA-mRNA Network Underlying Decidualized Endometriotic Cyst Stromal Cells Using Bioinformatics Analysis
Background. Decidualization of ectopic endometrium often leads to the extensive proliferation of local tissue and is easily misdiagnosed as malignant tumors. The study is aimed at constructing a microRNA- (miRNA-) mRNA network underlying decidualized endometriotic cyst stromal cells (ECSCs). Methods. All data were collected from the Gene Expression Omnibus (GEO) database. Firstly, the differentially expressed genes (DEGs, adj. , | log FC | ≥1) and miRNAs (DEMs, ,) were analyzed by the limma package....
BioMed Research International
Wed Aug 19, 2020 17:05
Status of Home Delivery and Its Associated Factors among Women Who Gave Birth within the Last 12 Months in East Badawacho District, Hadiya Zone, Southern Ethiopia
Background. Home delivery is responsible to maternal mortality due to obstetric complication like hemorrhage, hypertensive disorders, and sepsis. The prevalence of home delivery is remained very high both nationally (73%) and regionally (SNNPR) with 74.5%. Efforts were made to increase institutional delivery through skilled birth attendance. But women still prefer home as a place of delivery. This study was done to determine whether home preference has association with home delivery or not and the...
BioMed Research International
Wed Aug 19, 2020 16:20
Adaptive Evolution of Feline Coronavirus Genes Based on Selection Analysis
Purpose. We investigated sequences of the feline coronaviruses (FCoV), which include feline enteric coronavirus (FECV) and feline infectious peritonitis virus (FIPV), from China and other countries to gain insight into the adaptive evolution of this virus. Methods. Ascites samples from 31 cats with suspected FIP and feces samples from 8 healthy cats were screened for the presence of FCoV. Partial viral genome sequences, including parts of the nsp12-nsp14, S, N, and 7b genes, were obtained and aligned...
BioMed Research International
Wed Aug 19, 2020 15:05
A Computationally Efficient Method for Hybrid EEG-fNIRS BCI Based on the Pearson Correlation
A hybrid brain computer interface (BCI) system considered here is a combination of electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS). EEG-fNIRS signals are simultaneously recorded to achieve high motor imagery task classification. This integration helps to achieve better system performance, but at the cost of an increase in system complexity and computational time. In hybrid BCI studies, channel selection is recognized as the key element that directly affects the system’s...
BioMed Research International
Wed Aug 19, 2020 14:50
Intermittent Hypoxic Exposure Reduces Endothelial Dysfunction
Intermittent exposure to hypoxia (IHE) increases the production of reactive oxygen and nitrogen species as well as erythropoietin (EPO), which stimulates the adaptation to intense physical activity. However, several studies suggest a protective effect of moderate hypoxia in cardiovascular disease (CVD) events. The effects of intense physical activity with IHE on oxi-inflammatory mediators and their interaction with conventional CVD risk factors were investigated. Blood samples were collected from...
BioMed Research International
Wed Aug 19, 2020 13:20
Coenzyme Q10 Sunscreen Prevents Progression of Ultraviolet-Induced Skin Damage in Mice
The level of sun ultraviolet ray reaching the surface of the earth is increasing severely due to the rapid development of the society and environmental destruction. Excessive exposure to ultraviolet radiation causes skin damage and photoaging. Therefore, it is emerged to develop effective sunscreen to prevent ultraviolet-induced skin damage. This study was aimed at investigating the effects of Coenzyme Q10 (CoQ10) sunscreen on the prevention of ultraviolet B radiation- (UVB-) induced mouse skin damage....
BioMed Research International
Wed Aug 19, 2020 13:05
Nrp-1 Mediated Plasmatic Ago2 Binding miR-21a-3p Internalization: A Novel Mechanism for miR-21a-3p Accumulation in Renal Tubular Epithelial Cells during Sepsis
The mechanism underlying sepsis-associated acute kidney injury (SAKI), which is an independent risk factor for sepsis-associated death, is unclear. A previous study indicates that during sepsis miR-21a-3p accumulates in renal tubular epithelial cells (TECs) as the mediator of inflammation and mediates TEC malfunction by manipulating its metabolism. However, the specific mechanism responsible for the accumulation of miR-21a-3p in TECs during sepsis is unrevealed. In this study, a cecal ligation and...
BioMed Research International
Wed Aug 19, 2020 12:20
Effect of a DPP-4 Inhibitor on Orthodontic Tooth Movement and Associated Root Resorption
Objectives. Dipeptidyl peptidase-4 (DPP-4) inhibitors are used as a treatment for type 2 diabetes mellitus and have also recently been applied to enhance bone quality and density, and increase the expression of bone markers. This study aimed to investigate the effect of a DPP-4 inhibitor on orthodontic tooth movement (OTM) and related root resorption in a mouse model. Materials and Methods. Mice were randomly divided into three groups: those undergoing OTM with the addition of a DPP-4 inhibitor (30 μg),...
BioMed Research International
Wed Aug 19, 2020 12:20
The Value of Real-Time Shear Wave Elastography before and after Rehabilitation of Upper Limb Spasm in Stroke Patients
Objective. Our goal was to evaluate the efficacy of muscle spasm before and after rehabilitation by comparing shear wave propagation velocity (SWV) and Young’s modulus (YM) in the normal and spastic biceps brachii in stroke patients. Methods. A study of 60 stroke patients with upper limb spasm was performed; these patients were admitted from April 2018 to September 2019. The modified Ashworth scale (MAS) scores of the spastic biceps brachii before and after rehabilitation treatment were compared....
BioMed Research International
Wed Aug 19, 2020 11:20
Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells
ARAF is a member of the RAF kinase family that is necessary for mitogen-activated protein kinase (MAPK) activation in various malignancies, including lung, colorectal, pancreatic, and breast cancers. As the most common biliary tract tumor, gallbladder cancer (GBC) seriously harms human health while the function of ARAF in GBC remains elusive. Here, we found that ARAF expression was upregulated in gallbladder cancer tissues. In vitro, ARAF silencing mediated by RNA interference effectively inhibited...
BioMed Research International
Wed Aug 19, 2020 11:20
Dynamic Hip Screw with Trochanter-Stabilizing Plate Compared with Proximal Femoral Nail Antirotation as a Treatment for Unstable AO/OTA 31-A2 and 31-A3 Intertrochanteric Fractures
Background. The dynamic hip screw (DHS) with the addition of an angular stable trochanter-stabilizing plate (TSP) has been considered the ideal treatment for the unstable intertrochanteric fracture type. However, there have been few comparisons between DHS+TSP augmentation with intramedullary (IM) nailing. The aim of this retrospectively registered study was to compare the clinical outcomes of patients with the unstable type of intertrochanteric fractures treated with DHS+TSP or IM nailing (proximal...
BioMed Research International
Wed Aug 19, 2020 11:20
Effects of Cigarette Smoke Condensate on Growth and Biofilm Formation by Mycobacterium tuberculosis
Background and Objectives. Cigarette smoke (CS) is a major risk factor contributing to the burden of tuberculosis. Little is known, however, about the effects of CS exposure on growth and persistence of Mycobacterium tuberculosis (Mtb) organisms. This issue has been addressed in the current study, which is focused on the effects of cigarette smoke condensate (CSC) on the growth and viability of Mtb planktonic and biofilm-forming cultures. Materials and Methods. The planktonic and biofilm-forming...
BioMed Research International
Wed Aug 19, 2020 09:50
Craniofacial Anomaly Association with the Internal Malformations in the Pediatric Age Group in Al-Fallujah City-Iraq
Context. Craniofacial anomalies (CFA) are a major cause of infant mortality and childhood morbidity. They may be simple or multiple and vary in their clinical importance. Objectives. To estimate the prevalence of craniofacial anomalies among Iraqi people and its association with other congenital malformations. Methods. A hospital-based cohort study. It was conducted in Iraq, Fallujah city from Jan 2019-April 2019. The pediatric age group below 16 years attending the consultation clinic. Results....
BioMed Research International
Wed Aug 19, 2020 09:50
ReadySim: A Computational Framework for Building Explicit Finite Element Musculoskeletal Simulations Directly from Motion Laboratory Data
Abstract Musculoskeletal modeling allows researchers insight into joint mechanics which might not otherwise be obtainable through in vivo or in vitro studies. Common musculoskeletal modeling techniques involve rigid body dynamics software which often employ simplified joint representations. These representations have proven useful but are limited in performing single‐framework deformable analyses in structures of interest. Musculoskeletal finite element (MSFE) analysis allows for representation...
International Journal for Numerical Methods in Biomedical Engineering
Wed Aug 19, 2020 12:39
Alginate Biomaterial Evades Immune System to Enhance Stem Cell Therapy
Researchers at Rice University and Baylor College of Medicine have developed an immuno-evasive alginate biomaterial hydrogel that can enhance stem cell therapy after myocardial infarction. Stem cells delivered to the heart within the biomaterial survive in greater numbers and for a longer period than cells delivered alone, resulting in a significant enhancement in healing. Stem cells hold huge promise as regenerative therapeutics, but they also demand specific requirements for successful...
Medgadget
Wed Aug 19, 2020 16:57
The long-term outcomes of deceased-donor liver transplantation for primary biliary cirrhosis: a two-center study in China
Background & Aims Factors that influence the outcomes after deceased-donor liver transplantation (DDLT) for primary biliary cirrhosis (PBC) are not well known. We aimed to clarify these effects on the outcomes after DDLT. Methods We retrospectively analyzed patients with PBC who underwent DDLT from March 2006 to July 2018 at the organ transplantation center of the First Hospital of Jilin University and the First...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
The antifungal activity of vapour phase of odourless thymol derivate
Thymol is a substance with a great therapeutic potential possessing antibacterial and antifungal activity, with a characteristic odour that remains long after application but is not pleasant at higher concentrations. In this study, attention has been focused on describing the chemical and biological properties of the simply prepared trimethylsilyl ether of thymol (kubicin). Interestingly, kubicin has similar volatility as thymol, undergoes hydrolysis in the water (moisture; forming thymol and trimethylsilanol)...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Using organic fertilizers to increase crop yield, economic growth, and soil quality in a temperate farmland
We used a constant total N application base rate to conduct a two-year field experiment comparing the effects of three organic fertilizers (rapeseed meal (RSM), soybean meal (SBM), and cattle manure (CM)) on the crop yield, economic growth, and soil quality of a winter wheat-summer maize rotation system. Winter wheat and summer maize in rapeseed meal treatment (RSMT), soybean meal treatment (SBMT), and cattle manure treatment (CMT) showed yield increases of 161%, 299%, and 256%, respectively, when...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Comparative assessment of single-stage and two-stage anaerobic digestion for biogas production from high moisture municipal solid waste
Background Anaerobic digestion (AD) is a suitable process for treating high moisture MSW with biogas and biofertilizer production. However, the low stability of AD performance and low methane production results from high moisture MSW due to the fast acidify of carbohydrate fermentation. The effects of organic loading and incineration fly ash addition as a pH adjustment on methane production from high moisture MSW in the single-stage AD and two-stage AD processes were investigated....
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Mutation density changes in SARS-CoV-2 are related to the pandemic stage but to a lesser extent in the dominant strain with mutations in spike and RdRp
Since its emergence in Wuhan, China in late 2019, the origin and evolution of SARS-CoV-2 have been among the most debated issues related to COVID-19. Throughout its spread around the world, the viral genome continued acquiring new mutations and some of them became widespread. Among them, 14408 C>T and 23403 A>G mutations in RdRp and S, respectively, became dominant in Europe and the US, which led to debates regarding their effects on the mutability and transmissibility of the virus. In this...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Satellite tracking reveals a new migration route of black-necked cranes (Grus nigricollis) in Qinghai-Tibet Plateau
Background The black-necked crane (Grus nigricollis) is a vulnerable species and the only species that lives in the plateau. Five migration routes of different populations have been identified, but for cranes wintering in Nyingchi Prefecture, Tibet, the migration route and breeding/summering area are still unknown. The aim of this study was to investigate the spatio-temporal migration patterns of black-necked cranes in this area and to identify important areas for conservation. ...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan
Genetic polymorphism in cytochrome P450 (CYP) monooxygenase genes is an important source of interindividual variability of drug response. CYP enzyme activities may change as a result of such polymorphisms which then, may affect drug metabolism. This would result in a change in the severity and frequency of adverse effects in addition to the non-responder phenomenon. CYP2E1, a member of CYP superfamily, affects the metabolism of several clinically important drugs such as halothane, paracetamol, etc....
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Population genomics reveals a mismatch between management and biological units in green abalone (Haliotis fulgens)
Effective fishery management strategies should be based on stock delimitation and knowledge of the spatial scale at which species are distributed. However, a mismatch often occurs between biological and management units of fishery resources. The green abalone (Haliotis fulgens) supports an important artisanal fishery in the west coast of the Baja California Peninsula (BCP), Mexico, which has shown a declining tendency despite the several management measures. Thus, the aim of this study was to characterize...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
A comparison of COVID-19, SARS and MERS
In mid-December 2019, a novel atypical pneumonia broke out in Wuhan, Hubei Province, China and was caused by a newly identified coronavirus, initially termed 2019 Novel Coronavirus and subsequently severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As of 19 May 2020, a total of 4,731,458 individuals were reported as infected with SARS-CoV-2 among 213 countries, areas or territories with recorded cases, and the overall case-fatality rate was 6.6% (316,169 deaths among 4,731,458 recorded...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Transcriptomic analysis highlights cochlear inflammation associated with age-related hearing loss in C57BL/6 mice using next generation sequencing
Background In our aging society, age-related hearing loss (AHL) is the most common sensory disorder in old people. Much progress has been made in understanding the pathological process of AHL over the past few decades. However, the mechanism of cochlear degeneration during aging is still not fully understood. Methods Next generation sequencing technique was used to sequence the whole transcriptome of the cochlea of C57BL/6 mice, a mouse model of AHL. Differentially expressed genes (DEGs)...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
The changes of morphological and physiological characteristics in hemiparasitic Monochasma savatieri before and after attachment to the host plant
Background Monochasma savatieri is an endangered hemiparasitic medicinal plant with a variety of antioxidant, antimicrobial and anti-inflammatory properties. Despite the urgent need to understand the parasitic biology of M. savatieri, parasite-host associations have long been neglected in studies of M. savatieri. Methods We conducted a pot cultivation experiment to analyze changes in the growth traits, physiological performance and anatomical structures of M. savatieri grown with the...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Evolution of the patella and patelloid in marsupial mammals
The musculoskeletal system of marsupial mammals has numerous unusual features beyond the pouch and epipubic bones. One example is the widespread absence or reduction (to a fibrous “patelloid”) of the patella (“kneecap”) sesamoid bone, but prior studies with coarse sampling indicated complex patterns of evolution of this absence or reduction. Here, we conducted an in-depth investigation into the form of the patella of extant marsupial species and used the assembled dataset to reconstruct the likely...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Dynamic visual attention characteristics and their relationship to match performance in skilled basketball players
Background Dynamic visual attention is important in basketball because it may affect the performance of players and thus the match outcome. The goals of this study were to investigate the difference in dynamic visual attention characteristics between highly skilled basketball players and nonathletic college students and to explore the relationship between visual attention and game-related performance among the basketball players. Methods In total, 24 highly skilled basketball players...
PeerJ Computer Science
Wed Aug 19, 2020 03:00
Six complete mitochondrial genomes of mayflies from three genera of Ephemerellidae (Insecta: Ephemeroptera) with inversion and translocation of trnI rearrangement and their phylogenetic relationships
As a small order of Pterygota (Insecta), Ephemeroptera has almost 3,500 species around the world. Ephemerellidae is a widely distributed common group of Ephemeroptera. However, the relationship among Ephemerellidae, Vietnamellidae and Teloganellidae is still in dispute. In this study, we sequenced six complete mitogenomes of three genera from Ephemerellidae (Insecta: Ephemeroptera): Ephemerella sp. Yunnan-2018, Serratella zapekinae, Serratella sp. Yunnan-2018, Serratella sp. Liaoning-2019, Torleya...
PeerJ Computer Science
Wed Aug 19, 2020 03:00

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