Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Τετάρτη 19 Αυγούστου 2020

 

Identifying essential components of surgical care delivery through quality improvement: An updated Surgical Assessment Tool.
Identifying essential components of surgical care delivery through quality improvement: An updated Surgical Assessment Tool. Int J Surg. 2020 Aug 15;: Authors: Lin Y, Raykar NP, Saluja S, Mukhopadhyay S, Sharma S, Frett B, Enumah S, Iverson KR, Johnson W, Meara JG, Shrime MG Abstract BACKGROUND: Surgical care is a cost-effective intervention with major public health impact. Yet, five billion people do not have access to surgical and anesthesia...
International Journal of Surgery
Wed Aug 19, 2020 13:32
Occult Lymph Node Metastasis in Early-Stage Glottic Cancer in the National Cancer Database.
Occult Lymph Node Metastasis in Early-Stage Glottic Cancer in the National Cancer Database. Laryngoscope. 2020 Aug 18;: Authors: Patel TR, Eggerstedt M, Toor J, Tajudeen BA, Husain I, Stenson K, Al-Khudari S Abstract OBJECTIVES: Early-stage glottic cancer (cT1-T2 cN0) may be treated by primary surgery or radiation. Elective treatment of the neck in clinically N0 disease is usually not performed due to low rates of regional lymph node metastasis....
Larynx
Wed Aug 19, 2020 16:01
Predictive value of CD8/FOXP3 ratio combined with PD-L1 expression for radiosensitivity in patients with squamous cell carcinoma of the larynx receiving definitive radiation therapy.
Predictive value of CD8/FOXP3 ratio combined with PD-L1 expression for radiosensitivity in patients with squamous cell carcinoma of the larynx receiving definitive radiation therapy. Head Neck. 2020 Aug 18;: Authors: Ono T, Azuma K, Kawahara A, Kakuma T, Sato F, Akiba J, Tanaka N, Abe T, Chitose SI, Umeno H Abstract BACKGROUND: Little is known about immune-related radiosensitivity in patients with squamous cell carcinoma of the larynx (SCC-L)...
Larynx
Wed Aug 19, 2020 16:01
Curative-intent radiotherapy for glottic carcinoma in situ.
Curative-intent radiotherapy for glottic carcinoma in situ. Head Neck. 2020 Aug 17;: Authors: Mendenhall WM, Morris CG, Amdur RJ, Hitchcock KE, Cheddha N, Dziegielewski PT Abstract BACKGROUND: The aim of the study was to update our experience treating patients with glottic carcinoma in situ (CIS) with curative radiotherapy (RT). METHODS: Fifty patients received continuous-course RT using once-daily fractionation. Twenty-eight (56%)...
Larynx
Wed Aug 19, 2020 16:01
Application of the HRES 5562 Camera Using the HSDI Technique in the Diagnosis of Glottal Insufficiencies in Teachers.
Application of the HRES 5562 Camera Using the HSDI Technique in the Diagnosis of Glottal Insufficiencies in Teachers. J Voice. 2020 Aug 14;: Authors: Kosztyła-Hojna B, Zdrojkowski M, Duchnowska E Abstract OBJECTIVE: Teachers are the largest group of professional voice users with predispositions to functional or organic changes in the larynx. The dysfunction of intrinsic muscles of the larynx frequently occurs which leads to changes in parameters...
Larynx
Wed Aug 19, 2020 16:01
Supraglottic subepithelial benign mass lesions: Focus on clinical features of sialolipoma-like lesion.
Supraglottic subepithelial benign mass lesions: Focus on clinical features of sialolipoma-like lesion. Auris Nasus Larynx. 2020 Aug 14;: Authors: Tachibana T, Kariya S, Wani Y, Komatsubara Y, Naoi Y, Kuroda K, Fushimi S, Hotta M, Haruna K, Nagatani T, Makino T, Kataoka Y, Nishizaki K Abstract OBJECTIVES: Sialolipoma has been classified as a benign soft tissue lesion in the 2017 World Health Organization classification of head and neck tumors....
Larynx
Wed Aug 19, 2020 16:01
Risk Factors for Laryngectomy for Dysfunctional Larynx After Organ Preservation Protocols: A Case-Control Analysis.
Risk Factors for Laryngectomy for Dysfunctional Larynx After Organ Preservation Protocols: A Case-Control Analysis. Otolaryngol Head Neck Surg. 2020 Aug 18;:194599820947702 Authors: Wu MP, Goldsmith T, Holman A, Kammer R, Parikh A, Devore EK, Emerick KS, Lin DT, Deschler DG, Richmon JD, Varvares MA, Naunheim MR Abstract OBJECTIVE: (1) To identify factors associated with severe dysfunctional larynx leading to total laryngectomy after curative...
Larynx
Wed Aug 19, 2020 16:01
Is a voice-specific instrument more indicative of stroboscopy results than common clinical queries?
Related Articles Is a voice-specific instrument more indicative of stroboscopy results than common clinical queries? Laryngoscope. 2020 04;130(4):992-999 Authors: DeVore EK, Carroll TL, Shin JJ Abstract OBJECTIVES: To determine whether the Voice Handicap Index-10 (VHI-10) predicts diagnoses made via laryngoscopy/stroboscopy, as compared to common clinical inquiries about vocal characteristics. METHODS: We prospectively collected data...
Larynx
Wed Aug 19, 2020 16:01
A 10-year study of the etiopathogenesis of cysts with a study of seromucinous glands in vocal folds.
Related Articles A 10-year study of the etiopathogenesis of cysts with a study of seromucinous glands in vocal folds. Laryngoscope. 2020 04;130(4):986-991 Authors: Nerurkar NK, Chitnis T, Gupta VK, Muzumdar G, Patel K, Bhuiyan P Abstract OBJECTIVE: An increasing number of vocal fold cysts excised, as compared to polyps, over the last decade led us to review these cases. We found a statistically significant increase in cysts excised as compared...
Larynx
Wed Aug 19, 2020 16:01
Selective stimulation of human intrinsic laryngeal muscles: Analysis in a mathematical three-dimensional space.
Related Articles Selective stimulation of human intrinsic laryngeal muscles: Analysis in a mathematical three-dimensional space. Laryngoscope. 2020 04;130(4):967-973 Authors: Broniatowski M, Grundfest-Broniatowski S, Schiefer M, Ludlow DH, Broniatowski DA, Tucker HM Abstract OBJECTIVES/HYPOTHESIS: Standard stimulating methods using square waves do not appropriately restore physiological control of individual intrinsic laryngeal muscles (ILMs)....
Larynx
Wed Aug 19, 2020 16:01
StatPearls
StatPearls Book. 2020 01 Authors: Abstract The recurrent laryngeal nerve (RLN) branches off the vagus nerve (cranial nerve X) and has an indirect course through the neck. It supplies innervation to all of the intrinsic muscles of the larynx, except for the cricothyroid muscles, as well as sensation to the larynx below the level of the vocal cords. The right RLN branches from CN X around the level of T1-T2 loops under the right subclavian artery traveling posteriorly,...
Larynx
Wed Aug 19, 2020 16:01
StatPearls
StatPearls Book. 2020 01 Authors: Abstract A papilloma is a benign (non-cancerous) tumor arising from an epithelial surface and usually known to grow in an outward direction. Commonly, a papilloma refers to squamous cell papillomas which appear as frond-like tumors that can develop almost anywhere on the body with squamous epithelium: Skin: as warts and cutaneous papillomas. Lip. Oral cavity. Eyelid. Tongue. Pharynx. Larynx. Esophagus. Cervix. Genital tract:...
Larynx
Wed Aug 19, 2020 16:01
StatPearls
StatPearls Book. 2020 01 Authors: Abstract Aspiration is a common problem that can occur in healthy or sick patients wherein pharyngeal secretions, food material, or gastric secretions enter the larynx and trachea and can descend into the lungs, causing an acute or chronic inflammatory reaction. The term chronic aspiration refers to a common condition that occurs in the elderly population, pediatric patients with certain neurological conditions, and chronically...
Larynx
Wed Aug 19, 2020 16:01
StatPearls
StatPearls Book. 2020 01 Authors: Abstract Angioneurotic edema is a relatively common presentation in the emergency department (ED). It presents as unpredictable frequent edematous episodes of cutaneous and mucosal tissues such as lips, eyes, oral cavity, larynx, and gastrointestinal system (GIS). Urticaria (hives) and angioedema are part of a spectrum of allergic symptoms and occasionally have a non-allergic etiology. Laryngeal edema causing airway obstruction...
Larynx
Wed Aug 19, 2020 16:01
Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Performance of Dura Sealant Patch in Reducing Cerebrospinal Fluid Leakage Following Elective Cranial Surgery: The ENCASE Trial Study Protocol.
Related Articles Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Performance of Dura Sealant Patch in Reducing Cerebrospinal Fluid Leakage Following Elective Cranial Surgery: The ENCASE Trial Study Protocol. Neurosurgery. 2020 02 01;86(2):E203-E208 Authors: van Doormaal TPC, Germans MR, Sie M, Brouwers B, Fierstra J, Depauw PRAM, Robe PA, Regli L Abstract BACKGROUND: Cerebrospinal fluid (CSF) leakage is one of the most...
leak of cerebrospinal fluid
Wed Aug 19, 2020 16:05
StatPearls
StatPearls Book. 2020 01 Authors: Abstract The intracranial cavity consists of three components: cerebrospinal fluid (CSF), blood, and brain tissue. CSF is contained within the subarachnoid space between the arachnoid and pia layers of the meninges. CSF is produced by a specialized vascular structure called choroid plexus within each ventricle of the brain. A blood-CSF barrier is formed by ependymal cells that line the ventricles and choroid epithelial cells...
leak of cerebrospinal fluid
Wed Aug 19, 2020 16:05
NRF2 in human neoplasm: Cancer biology and potential therapeutic target.
NRF2 in human neoplasm: Cancer biology and potential therapeutic target. Pharmacol Ther. 2020 Aug 15;:107664 Authors: Liu Y, Lang F, Yang C Abstract Nuclear factor-erythroid 2-related factor 2 (NRF2) is a master regulator of a series of cytoprotective genes, which protects cells from stress conditions such as reactive oxygen species (ROS) and electrophiles. Besides its pivotal role in cellular physiology and stress response, several recent...
Oncology
Wed Aug 19, 2020 14:29
COVID-19 and Oncology: Service transformation during pandemic.
COVID-19 and Oncology: Service transformation during pandemic. Cancer Med. 2020 Aug 18;: Authors: Leung MST, Lin SG, Chow J, Harky A Abstract BACKGROUND: The COVID-19 pandemic has challenged healthcare systems around the world, where resources have refocused on increasing critical bed capacity to prepare for the peak in incidence of COVID-19. Oncology faces an unprecedented challenge as patients require multidisciplinary care and are more likely...
Oncology
Wed Aug 19, 2020 14:29
Screening for intra-anal squamous intraepithelial lesions in women with a history of human papillomavirus related vulvar or perianal disease: results of a screening protocol.
Screening for intra-anal squamous intraepithelial lesions in women with a history of human papillomavirus related vulvar or perianal disease: results of a screening protocol. Colorectal Dis. 2020 Aug 18;: Authors: Leber K, van Beurden M, Zijlmans HJ, Dewit L, Richel O, Vrouenraets SME Abstract AIM: Women with a history of human papillomavirus (HPV) related cervical, vaginal or vulvar high-grade squamous intraepithelial lesions (HSIL) or cancer...
Oncology
Wed Aug 19, 2020 14:29
Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy.
Extracellular vesicles engineered with valency-controlled DNA nanostructures deliver CRISPR/Cas9 system for gene therapy. Nucleic Acids Res. 2020 Aug 18;: Authors: Zhuang J, Tan J, Wu C, Zhang J, Liu T, Fan C, Li J, Zhang Y Abstract Extracellular vesicles (EVs) hold great promise for transporting CRISPR-Cas9 RNA-guided endonucleases (RNP) throughout the body. However, the cell-selective delivery of EVs is still a challenge. Here, we designed...
Oncology
Wed Aug 19, 2020 14:29
The evolution of the nasopharyngeal carcinoma staging system over a 10-year period: implications for future revisions.
The evolution of the nasopharyngeal carcinoma staging system over a 10-year period: implications for future revisions. Chin Med J (Engl). 2020 Aug 17;: Authors: Tang SQ, Mao YP, Xu C, Guo R, Li WF, Tang LL, Sun Y, Ma J Abstract BACKGROUND: The classification criteria and staging groups for nasopharyngeal carcinoma described in the Union for International Cancer Control/American Joint Committee on Cancer (UICC/AJCC) staging system have been...
Oncology
Wed Aug 19, 2020 14:29
The Cancer Patient and Cardiology.
The Cancer Patient and Cardiology. Eur J Heart Fail. 2020 Aug 18;: Authors: Zamorano JL, Gottfridsson C, Asteggiano R, Atar D, Badimon L, Bax JJ, Cardinale D, Cardone A, Feijen EAM, Ferdinandy P, López-Fernández T, Gale CP, Maduro JH, Moslehi J, Omland T, Gomez JCP, Scott J, Suter TM, Minotti G Abstract Advances in cancer treatment have improved clinical outcomes, leading to an increasing population of cancer survivors. Yet, this success is...
Oncology
Wed Aug 19, 2020 14:29
Radiomics in predicting treatment response in non-small-cell lung cancer: current status, challenges and future perspectives.
Radiomics in predicting treatment response in non-small-cell lung cancer: current status, challenges and future perspectives. Eur Radiol. 2020 Aug 18;: Authors: Chetan MR, Gleeson FV Abstract OBJECTIVES: Radiomics is the extraction of quantitative data from medical imaging, which has the potential to characterise tumour phenotype. The radiomics approach has the capacity to construct predictive models for treatment response, essential for the...
Oncology
Wed Aug 19, 2020 14:29
Clinicopathological Characteristics and Incidence of Gastric Cancer in Eastern India: A Retrospective Study.
Clinicopathological Characteristics and Incidence of Gastric Cancer in Eastern India: A Retrospective Study. J Gastrointest Cancer. 2020 Aug 18;: Authors: Ghosh P, Mandal S, Mitra Mustafi S, Murmu N Abstract PURPOSE: To study the association of gastric cancer with various clinicopathological traits in eastern India which can be used as an important factor for further analysis, understanding of the diseases and amelioration of patients. ...
Oncology
Wed Aug 19, 2020 14:29
Potential strategies for prevention of tumor spillage in minimally invasive radical hysterectomy.
Potential strategies for prevention of tumor spillage in minimally invasive radical hysterectomy. J Gynecol Oncol. 2020 Sep;31(5):e73 Authors: Bebia V, Monreal-Clua S, Pérez-Benavente A, Franco-Camps S, Díaz-Feijoo B, Gil-Moreno A Abstract OBJECTIVE: The publication of a prospective [1] and several retrospective [2,3] studies describing a worse prognosis in patients affected with early-stage cervical cancer who underwent a minimally invasive...
Oncology
Wed Aug 19, 2020 14:29
Keys to successful implementation of routine symptom monitoring in head and neck oncology with "Healthcare Monitor" and patients' perspectives of quality of care.
Keys to successful implementation of routine symptom monitoring in head and neck oncology with "Healthcare Monitor" and patients' perspectives of quality of care. Head Neck. 2020 Aug 18;: Authors: Dronkers EAC, Baatenburg de Jong RJ, van der Poel EF, Sewnaik A, Offerman MPJ Abstract BACKGROUND: Value-based health care is increasingly used to facilitate a systematic approach during follow-up of patients. We developed Healthcare Monitor (HM):...
Oncology
Wed Aug 19, 2020 14:29
Understanding the trajectory of research efforts in atypical teratoid rhabdoid tumors: a bibliometric analysis of the 50 most impactful studies to date.
Understanding the trajectory of research efforts in atypical teratoid rhabdoid tumors: a bibliometric analysis of the 50 most impactful studies to date. Childs Nerv Syst. 2020 Aug 17;: Authors: Siada RG, Lu VM, Daniels DJ Abstract PURPOSE: Atypical teratoid/rhabdoid tumor (ATRT) is a highly malignant embryonal tumor of the central nervous system (CNS) that occurs predominantly in children. More is being discovered about this disease to improve...
Oncology
Wed Aug 19, 2020 14:29
Autologous tissue reconstruction after mastectomy-A cross-sectional survey of 110 hospitals in China.
Autologous tissue reconstruction after mastectomy-A cross-sectional survey of 110 hospitals in China. Eur J Surg Oncol. 2020 Jul 29;: Authors: Wang J, Xiu B, Guo R, Zhang Q, Su Y, Li L, Chi W, Shao Z, Wu J Abstract BACKGROUND: Autologous reconstruction after mastectomy became more and more popular, so this study aimed to obtain up-to-date and comprehensive data on autologous reconstruction in China. METHODS: An electronic questionnaire...
Oncology
Wed Aug 19, 2020 14:29
A service line approach: Using whiteboard analytics to improve time efficiency in radiation oncology.
A service line approach: Using whiteboard analytics to improve time efficiency in radiation oncology. Med Dosim. 2020 Aug 14;: Authors: Patel S, Sutlief S, Dennis K, Parikh S, Turner L Abstract The purpose of this study was to develop and implement a custom-designed electronic workflow management tool created by Medlever, Inc, in order to improve efficiency, leverage interoperability and maximize overall labor resources. Administrators and...
Oncology
Wed Aug 19, 2020 14:29
Recurrence patterns and postrecurrence survival after curative intent resection for pancreatic ductal adenocarcinoma.
Recurrence patterns and postrecurrence survival after curative intent resection for pancreatic ductal adenocarcinoma. Surgery. 2020 Aug 14;: Authors: Kolbeinsson H, Hoppe A, Bayat A, Kogelschatz B, Mbanugo C, Chung M, Wolf A, Assifi MM, Wright GP Abstract BACKGROUND: Pancreatic ductal adenocarcinoma has a high rate of recurrence after resection. We aimed to investigate patterns of recurrence of pancreatic ductal adenocarcinoma to identify opportunities...
Oncology
Wed Aug 19, 2020 14:29
Ethical considerations related to radiosensitivity and radiosusceptibility.
Related Articles Ethical considerations related to radiosensitivity and radiosusceptibility. Int J Radiat Biol. 2020 03;96(3):340-343 Authors: Kalman C, Oughton D Abstract Purpose: The potential for individual radiosensitivity and radiosusceptibility testing, both in clinical practice and in systems of radiological protection, raises complex ethical considerations which must be addressed both in relation to the scientific research looking at...
Oncology
Wed Aug 19, 2020 14:29
Effectiveness of diffusion-weighted imaging in predicting cervical lymph node metastasis in head and neck malignancies.
Effectiveness of diffusion-weighted imaging in predicting cervical lymph node metastasis in head and neck malignancies. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 11;: Authors: Zhou Y, Yu T, Rui X, Jin T, Huang Z, Huang Z Abstract OBJECTIVE: The aim of this study was to evaluate the effectiveness of diffusion-weighted imaging (DWI) in predicting cervical lymph node metastasis in head and neck malignancies. STUDY DESIGN:...
oral surg oral med
Wed Aug 19, 2020 15:14
Idiopathic condylar resorption: a systematic review of etiology and management.
Idiopathic condylar resorption: a systematic review of etiology and management. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jul 21;: Authors: Ji YD, Resnick CM, Peacock ZS Abstract OBJECTIVE: The aim of this study was to evaluate the level of evidence in the literature on etiology and management of idiopathic condylar resorption (ICR) of the mandible. STUDY DESIGN: A systematic search of articles published from 1982 to 2019...
oral surg oral med
Wed Aug 19, 2020 15:14
Airway Hygiene in COVID-19 Pneumonia: Treatment Responses of 3 Critically Ill Cruise Ship Employees.
Airway Hygiene in COVID-19 Pneumonia: Treatment Responses of 3 Critically Ill Cruise Ship Employees. Am J Case Rep. 2020 Aug 18;21:e926596 Authors: Farooqi FI, Morgan RC, Dhawan N, Dinh J, Yatzkan G, Michel G Abstract BACKGROUND COVID-19, the disease entity caused by the novel severe acute respiratory coronavirus 2 (SARS-CoV-2), continues to pose a major therapeutic challenge for clinicians. At present, an effective treatment regimen and vaccination...
pubmed: "am j case rep"[jour...
Wed Aug 19, 2020 15:25
Malignant Otitis External: Our Experience and Literature Review.
Malignant Otitis External: Our Experience and Literature Review. Am J Case Rep. 2020 Aug 18;21:e925060 Authors: Di Lullo AM, Russo C, Piroli P, Petti A, Capriglione P, Cantone E, Motta G, Iengo M, Elefante A, Cavaliere M Abstract BACKGROUND Malignant external otitis (MEO) is an invasive infection that can involve the external auditory canal and the skull base up to the contiguous soft tissues. Considering the changing face of MEO, we reviewed...
pubmed: "am j case rep"[jour...
Wed Aug 19, 2020 15:25
A 31-Year-Old Man with COVID-19-Associated Empyema and Lupus Anticoagulant.
A 31-Year-Old Man with COVID-19-Associated Empyema and Lupus Anticoagulant. Am J Case Rep. 2020 Aug 18;21:e926623 Authors: Yarlagadda K, Mi K, Sendil S, Koons CL, Komanduri S, Cinicola JT Abstract BACKGROUND COVID-19 was declared a pandemic in March 2020 in the United States. It has been associated with high mortality and morbidity all over the world. COVID-19 can cause a significant inflammatory response leading to coagulopathy and this hypercoagulable...
pubmed: "am j case rep"[jour...
Wed Aug 19, 2020 15:25
Droplet Exposure Risk to Providers From In-Office Flexible Laryngoscopy: A COVID-19 Simulation.
Droplet Exposure Risk to Providers From In-Office Flexible Laryngoscopy: A COVID-19 Simulation. Otolaryngol Head Neck Surg. 2020 Aug 18;:194599820952800 Authors: Ye MJ, Sharma D, Rubel KE, Lebo NL, Burgin SJ, Illing EA, Ting JY, Moore MG, Yesensky JA, Mantravadi AV, Sim MW Abstract To provide data on risk of respiratory droplets from common otolaryngologic procedures during the COVID-19 pandemic, a novel simulation of droplet exposure...
pubmed: "otolaryngol head ne...
Wed Aug 19, 2020 14:58
Tracheostomy in COVID-19 Patients: Why Delay or Avoid?
Tracheostomy in COVID-19 Patients: Why Delay or Avoid? Otolaryngol Head Neck Surg. 2020 Aug 18;:194599820953371 Authors: Kwak PE, Persky MJ, Angel L, Rafeq S, Amin MR PMID: 32808866 [PubMed - as supplied by publisher]
pubmed: "otolaryngol head ne...
Wed Aug 19, 2020 14:58

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