Related Articles National Database Research in Head and Neck Reconstructive Surgery: A Call for Increased Transparency and Reproducibility. Otolaryngol Head Neck Surg. 2020 Jul 07;:194599820938044 Authors: Bur AM, Villwock MR, Nallani R, Gomez ED, Varvares MA, Villwock JA, Cannady SB, Wax MK Abstract OBJECTIVE: To reproduce a published study comparing outcomes of patients who underwent microvascular reconstruction by plastic surgeons and...
Wed Jul 08, 2020 14:40
Predictors of Free Flap Volume Loss in Nonosseous Reconstruction of Head and Neck Oncologic Defects.
Related Articles Predictors of Free Flap Volume Loss in Nonosseous Reconstruction of Head and Neck Oncologic Defects. Ear Nose Throat J. 2020 Jul 07;:145561320938903 Authors: Razavi CR, Hostetter J, Shukla A, Cheng Z, Aygun N, Boahene K, Byrne PJ, Richmon J, Quon H, Desai SC Abstract OBJECTIVES: Free tissue reconstruction of the head and neck must be initially overcorrected due to expected postoperative free flap volume loss, which can...
Wed Jul 08, 2020 14:40
Related Articles COVID-19 Pandemic and Head and Neck Surgery Residency Program: Proposals for the "Phase 2". Ear Nose Throat J. 2020 Jul 07;:145561320940120 Authors: De Luca P, Petrosino M, Calvanese M, Colacurcio V, Bisogno A, Marra P, De Bonis E, Troisi D PMID: 32633654 [PubMed - as supplied by publisher]
Wed Jul 08, 2020 14:40
Related Articles Vasodilation by Verapamil-Nitroglycerin Solution in Microvascular Surgery. Otolaryngol Head Neck Surg. 2020 Jul 07;:194599820937991 Authors: Seth R, Badran KW, Cedars E, Plonowska K, Benjamin T, Saggi S, Knott PD, Heaton CM, Blackwell KE Abstract OBJECTIVE: Papaverine is a topical vasodilator commonly used during microvascular surgery to inhibit undesired vasoconstriction. A previous national shortage of papaverine prompted...
Wed Jul 08, 2020 14:40
Related Articles Relationship between Insurance Type and Delays in Tympanostomy Tube Placement. Ann Otol Rhinol Laryngol. 2020 Jul 07;:3489420940333 Authors: Schwartz M, Shah R, Wetzel M, Raol N Abstract OBJECTIVE: To investigate the role of insurance carriers and changes in insurance on rates of cancelation and rescheduling of tympanostomy tube surgery. METHODS: Retrospective cohort study between January 1, 2013 and December...
Wed Jul 08, 2020 14:40
Related Articles Identification of PTK7 as a promising therapeutic target for thyroid cancer. Eur Rev Med Pharmacol Sci. 2020 Jun;24(12):6809-6817 Authors: Duan F, Tang J, Kong FL, Zou HW, Ni BL, Yu JC Abstract OBJECTIVE: To evaluate the possible involvement of PTK7 in the progression of human thyroid cancer and assess its potential effects on the proliferation and apoptosis of thyroid cancer. PATIENTS AND METHODS: Immunohistochemical...
Wed Jul 08, 2020 14:40
Related Articles Knockdown of FOXM1 suppresses cell growth and metastasis in human laryngeal cancer via the AKT signaling pathway. Eur Rev Med Pharmacol Sci. 2020 Jun;24(12):6786-6793 Authors: Yan J, Hou J, Yan Y, Ren XY, Luo HN, Wang ZG, Zheng GX Abstract OBJECTIVE: This study aims to investigate the potential regulatory effect of forkhead box M1 (FOXM1) on laryngeal carcinoma (LC) and the underlying mechanisms. PATIENTS AND...
Wed Jul 08, 2020 14:40
Related Articles High expression of MMP14 is associated with progression and poor short-term prognosis in muscle-invasive bladder cancer. Eur Rev Med Pharmacol Sci. 2020 Jun;24(12):6605-6615 Authors: Wang JF, Gong YQ, He YH, Ying WW, Li XS, Zhou XF, Zhou LQ Abstract OBJECTIVE: To evaluate the short-term prognostic value of matrix metalloproteinase 14 (MMP14) in muscle-invasive bladder cancer (MIBC). PATIENTS AND METHODS: Expression...
Wed Jul 08, 2020 14:40
Related Articles Tumor control via targeting PD-L1 with chimeric antigen receptor modified NK cells. Elife. 2020 Jul 07;9: Authors: Robbins Y, Greene S, Friedman J, Clavijo PE, Van Waes C, Fabian KP, Padget MR, Abdul Sater H, Lee JH, Soon-Shiong P, Gulley J, Schlom J, Hodge JW, Allen CT Abstract Failed T cell-based immunotherapies in the presence of genomic alterations in antigen presentations pathways may be overcome by NK cell-based immunotherapy....
Wed Jul 08, 2020 14:40
Related Articles Association of Metformin With the Growth of Vestibular Schwannomas. Otolaryngol Head Neck Surg. 2020 Jul 07;:194599820937970 Authors: Tran S, Killeen DE, Qazi S, Balachandra S, Hunter JB Abstract OBJECTIVE: To assess whether medication use, specifically statin, metformin, and aspirin, affects the growth of vestibular schwannomas (VSs). STUDY DESIGN: Retrospective case series. SETTING: Single tertiary...
Wed Jul 08, 2020 14:40
Related Articles Swallowing Patterns in the HNC Population: Timing of Penetration-Aspiration Events and Residue. Otolaryngol Head Neck Surg. 2020 Jul 07;:194599820933883 Authors: Pisegna JM, Langmore SE, Meyer TK, Pauloski B Abstract OBJECTIVE: This study described swallowing patterns in a large head/neck cancer (HNC) cohort. STUDY DESIGN: In a retrospective review of data from a randomized controlled trial, we studied timing...
Wed Jul 08, 2020 14:40
Related Articles Comparison of Survival Estimates Following Recurrence, Persistence, or Second Primary Malignancy in Oropharyngeal Squamous Cell Carcinoma. Otolaryngol Head Neck Surg. 2020 Jul 07;:194599820932872 Authors: Asarkar A, Flores JM, Nathan CO Abstract OBJECTIVE: This study investigated survival among patients with oropharyngeal squamous cell carcinoma (OPSCC) after recurrence, persistence, and second primary malignancies (SPMs)....
Wed Jul 08, 2020 14:40
Related Articles Effect of COVID-19 in selecting otolaryngology as a specialty. Head Neck. 2020 Jul;42(7):1409-1410 Authors: Go B, Rajasekaran K Abstract Coronavirus disease 2019 has undoubtedly impacted the health care system while causing lasting and profound implications for medical education. Senior medical students seeking exposure to the field of otolaryngology now find themselves in the challenging position of obtaining the experiences...
Wed Jul 08, 2020 14:40
Related Articles How fragile we are. Head Neck. 2020 Jul;42(7):1355-1360 Authors: Hanna E PMID: 32633092 [PubMed - in process]
Wed Jul 08, 2020 14:40
Related Articles Arrested pneumatization of the skull base: an under-recognized skull base anomaly. ANZ J Surg. 2020 Jul 07;: Authors: Duignan M, Wood A PMID: 32633019 [PubMed - as supplied by publisher]
Wed Jul 08, 2020 14:40
Related Articles The addition of tumour-stroma ratio to the 8th AJCC staging system improves survival prediction in oral tongue squamous cell carcinoma. Histopathology. 2020 Jul 07;: Authors: Mascitti M, Zhurakivska K, Togni L, Caponio VCA, Almangush A, Balercia P, Balercia A, Rubini C, Lo Muzio L, Santarelli A, Troiano G Abstract BACKGROUND: One of the objectives of current researches is to customise the treatment of cancer patients. This...
Wed Jul 08, 2020 14:40
Related Articles Light Sheet Microscopy of the Gerbil Cochlea. J Comp Neurol. 2020 Jul 06;: Authors: Hutson KA, Pulver SH, Ariel P, Naso C, Fitzpatrick DC Abstract Light Sheet Fluorescence Microscopy (LSFM) provides a rapid and complete three-dimensional image of the cochlea. The method retains anatomical relationships - on a micron scale - between internal structures such as hair cells, basilar membrane and modiolus with external surface...
Wed Jul 08, 2020 14:40
Related Articles Systematic review and meta-analysis of racial survival disparities among oropharyngeal cancer cases by HPV status. Head Neck. 2020 Jul 07;: Authors: Stein E, Lenze NR, Yarbrough WG, Hayes DN, Mazul A, Sheth S Abstract BACKGROUND: There is a well documented racial disparity in overall survival for oropharyngeal squamous cell carcinoma (OPSCC); however, it is unknown to what extent this disparity varies by HPV-status. ...
Wed Jul 08, 2020 14:40
Related Articles Epidemiology of cutaneous sebaceous carcinoma. Australas J Dermatol. 2020 Jul 06;: Authors: Wu A, Rajak SN, Chiang CJ, Lee WC, Huilgol SC, Selva D Abstract There has been uncertainty about the demographics and anatomical distribution of cutaneous sebaceous carcinoma. This study aims to investigate these uncertainties by analysing data from various countries. Data were obtained from cancer registries of the United States,...
Wed Jul 08, 2020 14:40
Related Articles Endoscopic versus microscopic ossiculoplasty in chronic otitis media: a systematic review of the literature. Eur Arch Otorhinolaryngol. 2020 Jul 07;: Authors: Tsetsos N, Vlachtsis K, Stavrakas M, Fyrmpas G Abstract OBJECTIVE: The aim of this study was to compare the endoscopic and microscopic ossiculoplasty in patients with chronic otitis media. METHODS: MEDLINE, ScienceDirect, and the Cochrane Library databases...
Wed Jul 08, 2020 14:40
Related Articles Design study of a dedicated head and neck cancer PET system. IEEE Trans Radiat Plasma Med Sci. 2020 Jul;4(4):489-497 Authors: Li M, Yockey B, Abbaszadeh S Abstract The tumor-involved regions of head and neck cancer (HNC) have complex anatomical structures and vital physiological roles. As a consequence, there is a need for high sensitivity and high spatial resolution dedicated HNC PET scanner. The purpose of this study...
Wed Jul 08, 2020 14:40
Related Articles Endogenous APOBEC3B overexpression characterizes HPV-positive and HPV-negative oral epithelial dysplasias and head and neck cancers. Mod Pathol. 2020 Jul 06;: Authors: Argyris PP, Wilkinson PE, Jarvis MC, Magliocca KR, Patel MR, Vogel RI, Gopalakrishnan R, Koutlas IG, Harris RS Abstract The DNA cytosine deaminase APOBEC3B (A3B) is a newly recognized endogenous source of mutations in a range of human tumors, including head/neck...
Wed Jul 08, 2020 14:40
Related Articles Intensity-Modulated Radiotherapy-Based Reirradiation for Head and Neck Cancer: A Multi-institutional Study by Korean Radiation Oncology Group (KROG 1707). Cancer Res Treat. 2020 Jul 07;: Authors: Lee J, Kim TH, Kim YS, Kim M, Park JW, Kim SH, Kim HJ, Lee CG Abstract Purpose: The benefits of reirradiation for head and neck cancer (HNC) have not been determined. This study evaluated the efficacy of reirradiation using intensity-modulated...
Wed Jul 08, 2020 14:40
Related Articles A RIPOR2 in-frame deletion is a frequent and highly penetrant cause of adult-onset hearing loss. J Med Genet. 2020 Jul 06;: Authors: de Bruijn SE, Smits JJ, Liu C, Lanting CP, Beynon AJ, Blankevoort J, Oostrik J, Koole W, de Vrieze E, Cremers CWRJ, Cremers FPM, Roosing S, Yntema HG, Kunst HPM, Zhao B, Pennings RJE, Kremer H, DOOFNL Consortium Abstract BACKGROUND: Hearing loss is one of the most prevalent disabilities worldwide,...
Wed Jul 08, 2020 14:40
Related Articles MicroRNA-223-3p regulates allergic inflammation by targeting INPP4A. Braz J Otorhinolaryngol. 2020 Jun 25;: Authors: Zhou Y, Zhang T, Yan Y, You B, You Y, Zhang W, Chen J Abstract INTRODUCTION: Emerging evidence indicates that physiological and pathological conditions of the nose are posttranscriptionally regulated by microRNAs, a class of small noncoding RNAs. Recently, microRNA-223-3p has been increasingly implicated in...
Wed Jul 08, 2020 13:12
Related Articles Primary squamous cell carcinoma of the parotid gland: clinicopathological characteristics, treatment, and prognosis. Int J Oral Maxillofac Surg. 2020 Jul 03;: Authors: Xiao M, Liu J, You Y, Yang X, Wang Y Abstract Squamous cell carcinoma (SCC) of the parotid gland is a rare aggressive malignancy with a poor prognosis. The clinical behaviour, histopathological characteristics, and treatment strategies for parotid SCC still...
Wed Jul 08, 2020 13:12
Related Articles Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease. J Otolaryngol Head Neck Surg. 2020 Jul 06;49(1):46 Authors: Song JS, Vallance P, Biron V, Jeffery CC Abstract BACKGROUND: With an increase in the incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) and more favourable survival outcomes, there is now a...
Wed Jul 08, 2020 13:12
Related Articles Inhibition of leucine-rich repeats and calponin homology domain containing 1 accelerates microglia-mediated neuroinflammation in a rat traumatic spinal cord injury model. J Neuroinflammation. 2020 Jul 06;17(1):202 Authors: Chen WK, Feng LJ, Liu QD, Ke QF, Cai PY, Zhang PR, Cai LQ, Huang NL, Lin WP Abstract BACKGROUND: Spinal cord injury (SCI) triggers the primary mechanical injury and secondary inflammation-mediated injury....
Wed Jul 08, 2020 13:12
Related Articles Predictors of Postoperative Radiation Following Laser Resection in Early-Stage Glottic Cancer. Otolaryngol Head Neck Surg. 2020 Jul 07;:194599820933183 Authors: Silverman DA, Zhan KY, Puram SV, Eskander A, Teknos TN, Rocco JW, Old MO, Kang SY Abstract OBJECTIVE: Guideline recommendations for the treatment of early-stage glottic cancer are limited to single-modality therapy with surgery or radiation alone. We sought to investigate...
Wed Jul 08, 2020 13:12
Related Articles Alexander Crum Brown: A Forgotten Pioneer in Vestibular Sciences. Otolaryngol Head Neck Surg. 2020 Jul 07;:194599820937671 Authors: Dasgupta S, Mandala M, Guneri EA Abstract Although vestibular anatomy was described in the Renaissance period, research in vestibular physiology began in the 1820s and was spearheaded by Purkinje and Flourens. This was subsequently expanded by Ménière, Helmholtz, Goltz, Mach, Breuer, Ewald,...
Wed Jul 08, 2020 13:12
Related Articles Recent Advances in the Application of Artificial Intelligence in Otorhinolaryngology-Head and Neck Surgery. Clin Exp Otorhinolaryngol. 2020 Jun 18;: Authors: Tama BA, Kim DH, Kim G, Lee S, Kim SW Abstract Objectives: To present an up-to-date survey of the use of artificial intelligence (AI) in the field of otorhinolaryngology, with respect to opportunities, research challenges, and research directions. Methods:...
Wed Jul 08, 2020 13:12
Related Articles Korean Modification of Nasal Provocation Test with House Dust Mites Antigen following EAACI Guidelines. Clin Exp Otorhinolaryngol. 2020 Jul 07;: Authors: Joo SH, Hyun KJ, Kim YH Abstract Objectives: We evaluated the usefulness of the standardized nasal provocation test (NPT) protocol published recently by the European Academy of Allergy, Asthma and Immunology (EAACI) and compared the utility of several parameters for diagnosing...
Wed Jul 08, 2020 13:12
Related Articles Sialolithiasis-Do Early Diagnosis and Removal Minimize Post-Operative Morbidity? Medicina (Kaunas). 2020 Jul 02;56(7): Authors: Avishai G, Ben-Zvi Y, Ghanaiem O, Chaushu G, Gilat H Abstract Background and objectives: Sialolithiasis is an inflammation of a salivary gland due to obstruction of salivary flow by a sialolith. We aim to assess potential factors that may predict lower morbidity following endoscopically assisted...
Wed Jul 08, 2020 13:12
Related Articles Macrophages in Oral Carcinomas: Relationship with Cancer Stem Cell Markers and PD-L1 Expression. Cancers (Basel). 2020 Jul 02;12(7): Authors: Suárez-Sánchez FJ, Lequerica-Fernández P, Suárez-Canto J, Rodrigo JP, Rodriguez-Santamarta T, Domínguez-Iglesias F, García-Pedrero JM, de Vicente JC Abstract Tumor-associated macrophages (TAMs) can be polarized into antitumoral M1 and protumoral and immunosuppressive M2 macrophages....
Wed Jul 08, 2020 13:12
Related Articles Insight into Salivary Gland Aquaporins. Cells. 2020 Jun 25;9(6): Authors: D'Agostino C, Elkashty OA, Chivasso C, Perret J, Tran SD, Delporte C Abstract The main role of salivary glands (SG) is the production and secretion of saliva, in which aquaporins (AQPs) play a key role by ensuring water flow. The AQPs are transmembrane channel proteins permeable to water to allow water transport across cell membranes according to...
Wed Jul 08, 2020 13:12
Related Articles Slug Is A Surrogate Marker of Epithelial to Mesenchymal Transition (EMT) in Head and Neck Cancer. J Clin Med. 2020 Jun 30;9(7): Authors: Steinbichler TB, Dudas J, Ingruber J, Glueckert R, Sprung S, Fleischer F, Cidlinsky N, Dejaco D, Kofler B, Giotakis AI, Skvortsova II, Riechelmann H Abstract BACKGROUND: Epithelial to mesenchymal transition (EMT) promotes therapy resistance in head and neck cancer (HNC) cells. In this...
Wed Jul 08, 2020 13:12
Related Articles Myeloid sarcoma of the nasal cavity in a 15-month-old child: A case report. Medicine (Baltimore). 2020 Jul 02;99(27):e21119 Authors: Liu R, Du J, Gao L, Liu Y, Liu S Abstract INTRODUCTION: Myeloid sarcoma (MS) is a rare tumor mass. It may occur at any extramedullary anatomic sites but is uncommon in the sinonasal location.MS commonly presents concurrently with acute myeloid leukemia (AML), but it may predate AML over several...
Wed Jul 08, 2020 13:12
Related Articles Comparison of the recurrence rate of 3 treatment modalities for Bowen disease in an aging city: A retrospective multivariate analysis. Medicine (Baltimore). 2020 Jul 02;99(27):e19893 Authors: Mo YW, Lee DL Abstract A wide range of therapeutic options are available for the treatment of Bowen disease. However, few studies have been conducted on wide excision using various resurfacing methods. The objectives of this study...
Wed Jul 08, 2020 13:12
Related Articles Unilateral sagittal split osteotomy: effect on mandibular symmetry in the treatment of class III with laterognathia. Prog Orthod. 2020 Jul 06;21(1):19 Authors: Abou Chebel N, Saadeh M, Haddad R Abstract The bilateral sagittal split osteotomy is considered the standard surgery to correct facial asymmetries. More recently, unilateral sagittal split osteotomy (USSO) was used to treat such malocclusions. AIM: To assess...
Wed Jul 08, 2020 13:12
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