IJMS, Vol. 21, Pages 4817: Distinct Proteomic Profile of Spermatozoa from Men with Seminomatous and Non-Seminomatous Testicular Germ Cell Tumors International Journal of Molecular Sciences doi: 10.3390/ijms21144817 Authors: Manesh Kumar Panner Selvam Marco G. Alves Tânia R. Dias Peter N. Pushparaj Ashok Agarwal Testicular germ cell tumors (TGCTs) are predominant in young males (15–44 years). Seminomatous and non-seminomatous TGCTs account for about 98% of all TGCTs...
Wed Jul 08, 2020 03:00
IJMS, Vol. 21, Pages 4816: Comparative Analysis, Structural Insights, and Substrate/Drug Interaction of CYP128A1 in Mycobacterium tuberculosis International Journal of Molecular Sciences doi: 10.3390/ijms21144816 Authors: Nokwanda Samantha Ngcobo Zinhle Edith Chiliza Wanping Chen Jae-Hyuk Yu David R. Nelson Jack A. Tuszynski Jordane Preto Khajamohiddin Syed Cytochrome P450 monooxygenases (CYPs/P450s) are well known for their role in organisms’ primary and...
Wed Jul 08, 2020 03:00
IJNS, Vol. 6, Pages 56: Why Do We Screen Newborn Infants for Cystic Fibrosis? International Journal of Neonatal Screening doi: 10.3390/ijns6030056 Authors: Jürg Barben Kevin W. Southern The introduction and widespread implementation of newborn bloodspot screening (NBS) for cystic fibrosis (CF) has offered earlier diagnosis and better outcomes for children with CF in many countries of the world [...]
Wed Jul 08, 2020 03:00
JCDD, Vol. 7, Pages 24: The Association of rs1898830 in Toll-Like Receptor 2 with Lipids and Blood Pressure Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7030024 Authors: Pia Chedid Ali Salami Said El Shamieh Background and Objective: Toll-like receptors (TLRs) are important components of the innate immune system, involved in establishing immunity to infections. Apart from being implicated in immunity, numerous studies have reported that many TLRs, including...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2165: Delirium Post-Stroke—Influence on Post-Stroke Dementia (Research Study—Part of the PROPOLIS Study) Journal of Clinical Medicine doi: 10.3390/jcm9072165 Authors: Jakub Droś Katarzyna Kowalska Paulina Pasińska Aleksandra Szyper-Maciejowska Agnieszka Gorzkowska Aleksandra Klimkowicz-Mrowiec Background: Previous research confirmed association between delirium and subsequent dementia in different clinical settings, but the impact of post-stroke delirium...
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JCM, Vol. 9, Pages 2163: Autism Spectrum Disorders in Greece: Nationwide Prevalence in 10–11 Year-Old Children and Regional Disparities Journal of Clinical Medicine doi: 10.3390/jcm9072163 Authors: Loretta Thomaidis Nikoletta Mavroeidi Clive Richardson Antigoni Choleva George Damianos Konstantinos Bolias Maria Tsolia Autism spectrum disorders (ASD) constitute a public health concern with increasing prevalence worldwide. We aimed to estimate prevalence and age at diagnosis...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2162: Distinct Microbiota Dysbiosis in Patients with Non-Erosive Reflux Disease and Esophageal Adenocarcinoma Journal of Clinical Medicine doi: 10.3390/jcm9072162 Authors: Jerry Zhou Prapti Shrestha Zhiguang Qiu David G. Harman Wun-Chung Teoh Sam Al-Sohaily Han Liem Ian Turner Vincent Ho Non-erosive reflux disease (NERD) and esophageal adenocarcinoma (EAC) are oftenregarded as bookends in the gastroesophageal reflux disease spectrum. However,...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2161: Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing Journal of Clinical Medicine doi: 10.3390/jcm9072161 Authors: Lucy V Trevor Kirsten Riches-Suman Ajay L Mahajan M Julie Thornton Interest in adipose tissue is fast becoming a focus of research after many years of being considered as a simple connective tissue. It is becoming increasingly apparent that adipose tissue contains a number of diverse cell types,...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2160: A Multidisciplinary Approach for Improving Quality of Life and Self-Management in Diabetic Kidney Disease: A Crossover Study Journal of Clinical Medicine doi: 10.3390/jcm9072160 Authors: Nancy Helou Dominique Talhouedec Maya Zumstein-Shaha Anne Zanchi Individuals with diabetic kidney disease are at high risk of complications and challenged to self-manage. Previous research suggested that multidisciplinary approaches would improve health outcomes. This...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2164: Sjögren’s Syndrome Minor Salivary Gland CD4+ Memory T Cells Associate with Glandular Disease Features and have a Germinal Center T Follicular Helper Transcriptional Profile Journal of Clinical Medicine doi: 10.3390/jcm9072164 Authors: Michelle L. Joachims Kerry M. Leehan Mikhail G. Dozmorov Constantin Georgescu Zijian Pan Christina Lawrence M. Caleb Marlin Susan Macwana Astrid Rasmussen Lida Radfar David M. Lewis Donald U. Stone Kiely...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2157: Anti-atherogenic Modification of Serum Lipoprotein Function in Patients with Rheumatoid Arthritis after Tocilizumab Treatment, a Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm9072157 Authors: Daniela Greco Roberta Gualtierotti Pasquale Agosti Maria Pia Adorni Francesca Ingegnoli Matteo Rota Franco Bernini Pier Luigi Meroni Nicoletta Ronda Lipid metabolism derangement contributes to increased cardiovascular risk in Rheumatoid...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2158: Obesity and COVID-19: Oro-Naso-Sensory Perception Journal of Clinical Medicine doi: 10.3390/jcm9072158 Authors: Amira Sayed Khan Aziz Hichami Naim Akhtar Khan Through a recent upsurge of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, the clinical assessment of most of the coronavirus disease 19 (COVID-19) patients clearly presents a health condition with the loss of oro-naso-sensory (ONS) perception, responsible for the detection...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2159: Role of Helicobacters in Neuropsychiatric Disease: A Systematic Review in Idiopathic Parkinsonism Journal of Clinical Medicine doi: 10.3390/jcm9072159 Authors: Rosalind M. Tucker Aisha D. Augustin Bu’ Hussain Hayee Ingvar Bjarnason David Taylor Clive Weller André Charlett Sylvia M Dobbs R John Dobbs Interest in an aetiopathogenic role for Helicobacter in neuropsychiatric diseases started with idiopathic parkinsonism (IP), where the cardinal...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2156: Radiomics Based on Thyroid Ultrasound Can Predict Distant Metastasis of Follicular Thyroid Carcinoma Journal of Clinical Medicine doi: 10.3390/jcm9072156 Authors: Mi-ri Kwon Jung Hee Shin Hyunjin Park Hwanho Cho Eunjin Kim Soo Yeon Hahn We aimed to evaluate whether radiomics analysis based on gray-scale ultrasound (US) can predict distant metastasis of follicular thyroid cancer (FTC). We retrospectively included 35 consecutive FTCs with distant...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2154: Motor and Cognitive Performance in Patients with Liver Cirrhosis with Minimal Hepatic Encephalopathy Journal of Clinical Medicine doi: 10.3390/jcm9072154 Authors: Constanza San Martín-Valenzuela Aroa Borras-Barrachina Juan-José Gallego Amparo Urios Víctor Mestre-Salvador Patricia Correa-Ghisays María-Pilar Ballester Desamparados Escudero-García Joan Tosca Cristina Montón María-Pilar Ríos Elena Kosenko Vicente Felipo Rafael Tabares-Seisdedos...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2151: Epileptiform Discharge and Electrographic Seizures during the Hypothermia Phase as Predictors of Rewarming Seizures in Children after Resuscitation Journal of Clinical Medicine doi: 10.3390/jcm9072151 Authors: Jainn-Jim Lin Mei-Hsin Hsu Shao-Hsuan Hsia Ying-Jui Lin Huei-Shyong Wang Hsuan-Chang Kuo Ming-Chou Chiang Oi-Wa Chan En-Pei Lee Kuang-Lin Lin the iCNS Group the iCNS Group The aim of this study was to determine the frequency,...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2155: Mitochondrial Alterations and Enhanced Human Leukocyte/Endothelial Cell Interactions in Type 1 Diabetes Journal of Clinical Medicine doi: 10.3390/jcm9072155 Authors: Francesca Iannantuoni Aranzazu M. de Marañon Zaida Abad-Jiménez Francisco Canet Pedro Díaz-Pozo Sandra López-Domènech Carlos Morillas Milagros Rocha Víctor M. Víctor Type 1 diabetes has been associated with oxidative stress. This study evaluates the rates of oxidative stress,...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2153: Should Lung-Sparing Surgery Be the Standard Procedure for Malignant Pleural Mesothelioma? Journal of Clinical Medicine doi: 10.3390/jcm9072153 Authors: Yoshinobu Ichiki Hidenori Goto Takashi Fukuyama Kozo Nakanishi Background: Surgical procedures for malignant pleural mesothelioma (MPM) include extrapleural pneumonectomy (EPP), extended pleurectomy/decortication (P/D) and P/D. EPP has been applied to MPM for a long time, but the postoperative status...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2152: Electrical Reverse Remodeling of the Native Cardiac Conduction System after Cardiac Resynchronization Therapy Journal of Clinical Medicine doi: 10.3390/jcm9072152 Authors: Hee-Jin Kwon Kyoung-Min Park Seong Soo Lee Young Jun Park Young Keun On June Soo Kim Seung-Jung Park Background: Little is known about electrical remodeling of the native conduction systems, particularly how the PR interval changes, after cardiac resynchronization therapy...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2145: Quality of Life Outcomes in Frontal Sinus Surgery Journal of Clinical Medicine doi: 10.3390/jcm9072145 Authors: Christos Georgalas Marios Detsis Ioannis Geramas Dimitris Terzakis Andreas Liodakis Introduction: Although significant experience has been gained in the technical nuances of endoscopic sinus surgery procedures, the patient-reported outcomes of frontal endoscopic sinus surgery procedures are still poorly understood. In this study we used...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2149: Organ Stiffness in the Work-Up of Myelofibrosis and Philadelphia-Negative Chronic Myeloproliferative Neoplasms Journal of Clinical Medicine doi: 10.3390/jcm9072149 Authors: Edoardo Benedetti Rita Tavarozzi Riccardo Morganti Benedetto Bruno Emilia Bramanti Claudia Baratè Serena Balducci Lorenzo Iovino Federica Ricci Vittorio Ricchiuto Gabriele Buda Sara Galimberti To define the role of spleen stiffness (SS) and liver stiffness...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2148: Association of Hypertensive Intracerebral Hemorrhage with Left Ventricular Hypertrophy on Transthoracic Echocardiography Journal of Clinical Medicine doi: 10.3390/jcm9072148 Authors: Lars-Peder Pallesen Jenny Wagner Dimitris Lambrou Silke Braun Matthias Weise Alexandra Prakapenia Jessica Barlinn Timo Siepmann Simon Winzer Haidar Moustafa Hagen H. Kitzler Kristian Barlinn Heinz Reichmann Volker Puetz Introduction: Arterial...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2150: The Impact of Dysphagia in Myositis: A Systematic Review and Meta-Analysis Journal of Clinical Medicine doi: 10.3390/jcm9072150 Authors: Bendix Labeit Marc Pawlitzki Tobias Ruck Paul Muhle Inga Claus Sonja Suntrup-Krueger Tobias Warnecke Sven G. Meuth Heinz Wiendl Rainer Dziewas (1) Background: Dysphagia is a clinical hallmark and part of the current American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) diagnostic...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2147: Sequential Strategy Including FFRCT Plus Stress-CTP Impacts on Management of Patients with Stable Chest Pain: The Stress-CTP RIPCORD Study Journal of Clinical Medicine doi: 10.3390/jcm9072147 Authors: Andrea Baggiano Laura Fusini Alberico Del Torto Patrizia Vivona Marco Guglielmo Giuseppe Muscogiuri Margherita Soldi Chiara Martini Enrico Fraschini Mark G. Rabbat Francesca Baessato Gloria Cicala Maria L. Danza Annachiara Cavaliere...
Wed Jul 08, 2020 03:00
JCM, Vol. 9, Pages 2146: A Comprehensive Machine-Learning Model Applied to Magnetic Resonance Imaging (MRI) to Predict Alzheimer’s Disease (AD) in Older Subjects Journal of Clinical Medicine doi: 10.3390/jcm9072146 Authors: Gopi Battineni Nalini Chintalapudi Francesco Amenta Enea Traini Increasing evidence suggests the utility of magnetic resonance imaging (MRI) as an important technique for the diagnosis of Alzheimer’s disease (AD) and for predicting the onset of...
Wed Jul 08, 2020 03:00
JFB, Vol. 11, Pages 49: Anti-Metastatic Effects of Plant Sap-Derived Extracellular Vesicles in a 3D Microfluidic Cancer Metastasis Model Journal of Functional Biomaterials doi: 10.3390/jfb11030049 Authors: Kimin Kim Jik-Han Jung Hye Ju Yoo Jae-Kyung Hyun Ji-Ho Park Dokyun Na Ju Hun Yeon Natural medicinal plants have attracted considerable research attention for their potential as effective drugs. The roots, leaves and stems of the plant, Dendropanax morbifera, which...
Wed Jul 08, 2020 03:00
JFB, Vol. 11, Pages 48: Controlled Release of 5-FU from Chi–DHA Nanoparticles Synthetized with Ionic Gelation Technique: Evaluation of Release Profile Kinetics and Cytotoxicity Effect Journal of Functional Biomaterials doi: 10.3390/jfb11030048 Authors: Mariarosa Ruffo Ortensia Ilaria Parisi Francesco Patitucci Marco Dattilo Rocco Malivindi Fabio Amone Catia Morelli Alessandra Nigro Diego Sisci Francesco Puoci The ionic gelation technique allows us to obtain...
Wed Jul 08, 2020 03:00
JFMK, Vol. 5, Pages 47: Endurance of the Dorsal and Ventral Muscles in the Neck Journal of Functional Morphology and Kinesiology doi: 10.3390/jfmk5030047 Authors: Cameron M. Liss Adeola A. Sanni Kevin K. McCully Endurance of the muscles of the neck are rarely studied. This study measured the endurance index (EI) of the sternocleidomastoid (SCM) and upper trapezius muscles of the neck (trap). The vastus lateralis (VL) was used for comparison. Skeletal muscle endurance of twelve...
Wed Jul 08, 2020 03:00
JoF, Vol. 6, Pages 103: In Vitro Interaction between Isavuconazole and Tacrolimus, Cyclosporin A, or Sirolimus against Aspergillus Species Journal of Fungi doi: 10.3390/jof6030103 Authors: Patrick Schwarz Eric Dannaoui The interaction of isavuconazole with immunosuppressors (tacrolimus, cyclosporin A, or sirolimus) against 30 Aspergillus isolates belonging to the most common species responsible for invasive aspergillosis in humans (Aspergillus flavus, Aspergillus fumigatus, Aspergillus...
Wed Jul 08, 2020 03:00
JoF, Vol. 6, Pages 102: Expression of Talaromyces marneffei acuM and acuK Genes in Gluconeogenic Substrates and Various Iron Concentrations Journal of Fungi doi: 10.3390/jof6030102 Authors: Monsicha Pongpom Artid Amsri Panwarit Sukantamala Phimchat Suwannaphong Juthatip Jeenkeawpieam Talaromyces marneffei is an opportunistic, dimorphic fungal pathogen that causes a disseminated infection in people with a weakened immunological status. The ability of this fungus to acquire...
Wed Jul 08, 2020 03:00
Medicina, Vol. 56, Pages 338: The Effect of Muscle Exercise on Perforators Flow: A Prospective Cohort Study Medicina doi: 10.3390/medicina56070338 Authors: Francesco Amendola Luca Vaienti Giuseppe Cottone Giovanna Zaccaria Zvi Steinberger Nicole Dereatti Michele Riccio Glenda Giorgia Caputo Francesco De Francesco Nicola Zingaretti Background and objectives: The metabolic response after exercise causes a significant increase in the muscle blood flow. While these...
Wed Jul 08, 2020 03:00
Medicina, Vol. 56, Pages 337: Dysautonomia in Alzheimer’s Disease Medicina doi: 10.3390/medicina56070337 Authors: Delia Tulbă Liviu Cozma Bogdan Ovidiu Popescu Eugenia Irene Davidescu Alzheimer’s disease is the most common neurodegenerative disorder, and its prevalence increases with age. Although there is a large amount of scientific literature focusing on Alzheimer’s disease cardinal cognitive features, autonomic nervous system dysfunction remains understudied...
Wed Jul 08, 2020 03:00
Medicina, Vol. 56, Pages 339: Trimebutine Maleate Monotherapy for Functional Dyspepsia: A Multicenter, Randomized, Double-Blind Placebo Controlled Prospective Trial Medicina doi: 10.3390/medicina56070339 Authors: Jannis Kountouras Emmanuel Gavalas Apostolis Papaefthymiou Ioannis Tsechelidis Stergios A. Polyzos Serhat Bor Mircea Diculescu Κhaled Jadallah Mazurek Tadeusz Tarkan Karakan Αnna Bochenek Jerzy Rozciecha Piotr Dabrowski Zeno Sparchez Orhan...
Wed Jul 08, 2020 03:00
Metabolites, Vol. 10, Pages 280: Potential Metabolite Nymphayol Isolated from Water Lily (Nymphaea stellata) Flower Inhibits MCF-7 Human Breast Cancer Cell Growth via Upregulation of Cdkn2a, pRb2, p53 and Downregulation of PCNA mRNA Expressions Metabolites doi: 10.3390/metabo10070280 Authors: Laila Naif Al-Harbi Pandurangan Subash-Babu Manal Abdulaziz Binobead Maha Hussain Alhussain Sahar Abdulaziz AlSedairy Amal A Aloud Ali A Alshatwi Controlled production of cyclin...
Wed Jul 08, 2020 03:00
Metabolites, Vol. 10, Pages 279: Regulatory T Cell Metabolism in Atherosclerosis Metabolites doi: 10.3390/metabo10070279 Authors: Jeroen Baardman Esther Lutgens Regulatory T cells (Tregs) are capable of suppressing excessive immune responses to prevent autoimmunity and chronic inflammation. Decreased numbers of Tregs and impaired suppressive function are associated with the progression of atherosclerosis, a chronic inflammatory disease of the arterial wall and the leading cause of...
Wed Jul 08, 2020 03:00
Metabolites, Vol. 10, Pages 278: Can We Trust Score Plots? Metabolites doi: 10.3390/metabo10070278 Authors: Marta Bevilacqua Rasmus Bro In this paper, we discuss the validity of using score plots of component models such as partial least squares regression, especially when these models are used for building classification models, and models derived from partial least squares regression for discriminant analysis (PLS-DA). Using examples and simulations, it is shown that the currently...
Wed Jul 08, 2020 03:00
Microorganisms, Vol. 8, Pages 1016: The Salmonella enterica Plasmidome as a Reservoir of Antibiotic Resistance Microorganisms doi: 10.3390/microorganisms8071016 Authors: Jean-Guillaume Emond-Rheault Jérémie Hamel Julie Jeukens Luca Freschi Irena Kukavica-Ibrulj Brian Boyle Sandeep Tamber Danielle Malo Eelco Franz Elton Burnett France Daigle Gitanjali Arya Kenneth Sanderson Martin Wiedmann Robin M. Slawson Joel T. Weadge Roger Stephan Sadjia...
Wed Jul 08, 2020 03:00
Microorganisms, Vol. 8, Pages 1017: Enteroviruses and T1D: Is It the Virus, the Genes or Both which Cause T1D Microorganisms doi: 10.3390/microorganisms8071017 Authors: Shirin Geravandi Huan Liu Kathrin Maedler Type 1 diabetes (T1D) is a chronic autoimmune disorder that results from the selective destruction of insulin-producing β-cells in the pancreas. Up to now, the mechanisms triggering the initiation and progression of the disease are, in their complexity, not fully...
Wed Jul 08, 2020 03:00
Microorganisms, Vol. 8, Pages 1015: Gut Microbiota and Dietary Intake of Normal-Weight and Overweight Filipino Children Microorganisms doi: 10.3390/microorganisms8071015 Authors: Maria Julia Golloso-Gubat Quinten R. Ducarmon Robby Carlo A. Tan Romy D. Zwittink Ed J. Kuijper Jacus S. Nacis Noelle Lyn C. Santos Diet and body mass index (BMI) have been shown to affect the gut microbiota of children, but studies are largely performed in developed countries. Here, we conducted...
Wed Jul 08, 2020 03:00
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