Surgical Infections, Ahead of Print.
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Tissue Engineering Part A, Ahead of Print.
Tissue Engineering Part A, Ahead of Print.
Tissue Engineering Part A, Ahead of Print.
Tissue Engineering Part A, Ahead of Print.
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Effect of photobiomodulation on CCC-ESF reactive oxygen species steady-state in high glucose mediums
Abstract Delayed wound healing is one of the most challenging complications of diabetes mellitus (DM) in clinical medicine, and it is related to the excessive generation of reactive oxygen species (ROS). Photobiomodulation (PBM) can promote wound healing in many ways, so it can be used as a method for the treatment of delayed healing of DM wounds. In this study, we investigated the effect of PBM on ROS homeostasis in human embryonic skin fibroblast cells (CCC-ESFs) cultured in...
Abstract Studying light penetration in biological tissues became a very important concern in various medical applications. It is an essential factor required to resolve the optical dose in many diagnostic and therapeutic procedures. The absorption and scattering properties of the inspected tissue control how deep the light will travel inside the tissue. However, these optical properties are highly dependent on the wavelength of the light source. In this work, the light transmission...
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Journal of Neurotrauma, Ahead of Print.
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Abstract Hypertriglyceridemia (HTG) can aggravate acute pancreatitis (AP), but its pathogenesis remains unclear. As autophagic activity is closely related to lipid metabolism and AP, we investigated the autophagic response in models of AP aggravated by HTG and explored whether rapamycin has a protective effect against HTG-related pancreatitis. HTG-associated AP models were established in vivo in rats and in vitro. The degree of inflammation,...
Abstract Paeonol, a major ingredient isolated from Moutan Cort, has various pharmacological effects. Our previous studies have shown that paeonol can exert antioxidant and anti-inflammatory therapeutic effects on ethanol-induced experimental gastric ulcer (GU). Therefore, in this study, we designed two GU models in rats induced by pyloric ligation (PL) and acetic acid and evaluated the protective effects of paeonol and gastroretention tablets...
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Presentation of Case. Dr. Kathy M. Tran: A 76-year-old woman was admitted to this hospital because of confusion and hypoxemia during the pandemic of coronavirus disease 2019 (Covid-19), the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The patient had been well…
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Antifungal drug discovery and design is very challenging because of the considerable similarities in genetic features and metabolic pathways between fungi and humans. However, cell wall composition represents a notable point of divergence. Therefore, a research strategy was designed to improve our understanding of the mechanisms for maintaining fungal cell wall integrity, and to identify potential targets for new drugs that modulate the underlying protein-protein interactions in Saccharomyces cerevisiae....
Currently available genome assemblies for Atlantic cod (Gadus morhua) have been constructed from fish belonging to the Northeast Arctic Cod (NEAC) population; a migratory population feeding in the Barents Sea. These assemblies have been crucial for the development of genetic markers which have been used to study population differentiation and adaptive evolution in Atlantic cod, pinpointing four discrete islands of genomic divergence located on linkage groups 1, 2, 7 and 12. In this paper, we present...
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Abstract This review looks at the advances in the surgical technique, selective dorsal rhizotomy, used for the management of spasticity in children.
Abstract Introduction Adults rarely present with tethered cord syndrome, and this review examines whether it is justifiable to perform surgical intervention in this group. Methods Between 2003 and 2017, we performed surgical intervention in 32 adults with tethered cord syndrome. The age range varied from 22 to 65 years. Twenty-six had pain, 20 had...
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Purpose: Purpose: We examined cabazitaxel, a novel next generation taxoid, in patients with metastatic gastric cancer in a multicenter phase II study. Experimental Design: Patients that have progressed on 1 or more prior therapies for locally advanced, unresectable or metastatic disease, were eligible and prior taxane therapy was allowed. Taxane-naïve and pretreated cohorts were analyzed independently for efficacy. The primary endpoint for both cohorts was progression-free survival (PFS) using...
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British Journal of Cancer, Published online: 09 July 2020; doi:10.1038/s41416-020-0956-xImpacts of combining anti-PD-L1 immunotherapy and radiotherapy on the tumour immune microenvironment in a murine prostate cancer model
British Journal of Cancer, Published online: 09 July 2020; doi:10.1038/s41416-020-0967-7Early treatment-related neutropenia predicts response to palbociclib
British Journal of Cancer, Published online: 09 July 2020; doi:10.1038/s41416-020-0973-9Cancer-associated fibroblasts mediate cancer progression and remodel the tumouroid stroma
British Journal of Cancer, Published online: 09 July 2020; doi:10.1038/s41416-020-0968-6Impact of mammographic screening and advanced cancer definition on the percentage of advanced-stage cancers in a steady-state breast screening programme in the Netherlands
British Journal of Cancer, Published online: 09 July 2020; doi:10.1038/s41416-020-0976-6EPS8 phosphorylation by Src modulates its oncogenic functions
British Journal of Cancer, Published online: 08 July 2020; doi:10.1038/s41416-020-0980-xConsiderations for the treatment of pancreatic cancer during the COVID-19 pandemic: the UK consensus position
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Abstract Knowledge, attitudes, and patient preferences about genetic testing and subsequent risk management for cancer prevention among average risk populations are understudied, especially among Hispanics. This study was to assess these items by conducting an in-person survey in this understudied population. We conducted in-person surveys using a self-administered, structured questionnaire among young women in 2017. Survey questions were adapted from other validated surveys....
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Abstract Objectives Agnathia-otocephaly complex is a rare condition characterized by mandibular hypoplasia or agnathia, ear anomalies (melotia/synotia) and microstomia with aglossia. This severe anomaly of the first branchial arch is most often lethal. The estimated incidence is less than 1 in 70.000 births, with etiologies linked to both genetic and teratogenic factors. Most of the cases are sporadic. To date, two genes have been described...
Abstract Objectives To evaluate the influence of diabetes on oxidative stress, periodontal ligament (PDL) orientation, and matrix metalloproteinase (MMP) 8 and 9 expressions during orthodontic tooth movement in a rat model. Materials and methods An orthodontic appliance was placed in 60 Sprague-Dawley rats divided into three groups: normoglycemics (n = 20)...
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The goal of this letter is not to underestimate the work done by Esposito et al in their review article [1]. Rather it is to draw attention to certain incorrect statements and conclusions concerning IBA Dosimetry’s products, which appear to be based on erroneous or misinterpreted information. The letter aims to clarify the recommended use, characteristics, abilities, and limitations of these products and emphasize to the radiotherapy community the intended clinical usage and benefits of the Compass...
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Analytical ChemistryDOI: 10.1021/acs.analchem.0c01232
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00824
Analytical ChemistryDOI: 10.1021/acs.analchem.0c02141
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00845
Analytical ChemistryDOI: 10.1021/acs.analchem.0c00247
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01393
Analytical ChemistryDOI: 10.1021/acs.analchem.0c01434
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