Σφακιανάκης Αλέξανδρος
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5 Άγιος Νικόλαος
Κρήτη 72100
00302841026182
00306932607174
alsfakia@gmail.com

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Τετάρτη 8 Ιουλίου 2020


Motor expertise affects the unconscious processing of geometric forms
Background The unconscious processing of information is an important skill used by competitive athletes to handle the rapidly changing movements of opponents and equipment. Previous studies have shown that unconscious information processing among athletes is better than that among non-athletes in the sports-specific domain. However, it is not yet clear whether athletes also show superior unconscious information processing in the general cognitive domain. ...
PeerJ Computer Science
Wed Jul 08, 2020 03:00
Successful promotion of physical activity among students of medicine through motivational interview and Web-based intervention
Background Regular physical activity supports healthy behavior and contributes to the reduction of preventable diseases. Students in their social transition period are the ideal groups for interventions. The higher education period, associated with demanding changes and poor time management, results in a low level of physical activity. In this age, social media usually are a suitable channel of communication and multicomponent interventions are the most desirable. It has not been sufficiently investigated...
PeerJ Computer Science
Wed Jul 08, 2020 03:00
Splenectomy enhances the Ly6C<sup>low</sup> phenotype in hepatic macrophages by activating the ERK1/2 pathway during liver fibrosis
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Zhongqiang Zheng, Huan Wang, Liang Li, Shaoying Zhang, Chunyan Zhang, Hailong Zhang, Fanpu Ji, Xi Liu, Kai Zhu, Guangyao Kong, Zongfang Li
ScienceDirect Publication: International Immunopharmacology
Wed Jul 08, 2020 13:45
Berberine ameliorates obesity-induced chronic inflammation through suppression of ER stress and promotion of macrophage M2 polarization at least partly via downregulating lncRNA Gomafu
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Yu-Bo Han, Miao Tian, Xiao-Xue Wang, De-Hui Fan, Wei-Zhong Li, Fan Wu, Li Liu
ScienceDirect Publication: International Immunopharmacology
Wed Jul 08, 2020 13:45
A model based on tumor-infiltrating immune cells for predicting the relapse rates of patients with testicular germ cell tumors
Publication date: September 2020Source: International Immunopharmacology, Volume 86Author(s): Yichun Wang, Chengjian Ji, Jinhui Liu, Yamin Wang, Ninghong Song, Pu Cao
ScienceDirect Publication: International Immunopharmacology
Wed Jul 08, 2020 13:45
Corrigendum to “Effect of low dose metronomic therapy on MCF-7 tumor cells growth and angiogenesis. Role of muscarinic acetylcholine receptors” [Int. Immunopharmacol. 84 (2020) 106514]
Publication date: August 2020Source: International Immunopharmacology, Volume 85Author(s): A.R. Salem, P. Martínez Pulido, F. Sanchez, Y. Sanchez, D. Rojo, A.J. Español, M.E. Sales
ScienceDirect Publication: International Immunopharmacology
Wed Jul 08, 2020 13:45
Corrigendum to “Schizandrin inhibits fibrosis and epithelial–mesenchymal transition in transforming growth factor-β1-stimulated AML12 cells” [Int. Immunopharmacol. 25 (2015) 276–284]
Publication date: August 2020Source: International Immunopharmacology, Volume 85Author(s): Ji-hyun Park, Jaewoo Yoon
ScienceDirect Publication: International Immunopharmacology
Wed Jul 08, 2020 13:45
Lithuanian version of nasolacrimal duct obstruction symptom scoring questionnaire. Cross‐cultural adaptation and validation. Short and long term results
Abstract Background The most common cause for epiphora is nasolacrimal duct obstruction (NLDO). Epiphora may decrease the quality of life due to recurrent lacrimal sac infections, worsening vision and distress in public environments. Patency of nasolacrimal duct can be verified by various clinical tests. However, there is no standardized questionnaire for symptom evaluation of NLDO patients. The objective of this study was to perform translation, cross‐cultural adaptation, and validation of the...
Wiley: Clinical Otolaryngology: Table of Contents
Tue Jul 07, 2020 20:31
Clinical phenotypes, genotypes and treatment in Chinese dystonia patients with KMT2B variants.
Related Articles Clinical phenotypes, genotypes and treatment in Chinese dystonia patients with KMT2B variants. Parkinsonism Relat Disord. 2020 Jun 09;77:76-82 Authors: Li XY, Dai LF, Wan XH, Guo Y, Dai Y, Li SL, Fang F, Wang XH, Zhang WH, Liu TH, Xie ZH, Fang T, Wang L, Ding CH Abstract BACKGROUND: KMT2B-related dystonia is a recently discovered hereditary dystonia that mostly occurs in childhood. This dystonia usually progresses to generalized...
Larynx
Wed Jul 08, 2020 17:45
Incidence of thyroid gland invasion in advanced laryngeal cancers and its impact on disease-specific survival; a retrospective review at a tertiary care center.
Related Articles Incidence of thyroid gland invasion in advanced laryngeal cancers and its impact on disease-specific survival; a retrospective review at a tertiary care center. Acta Otolaryngol. 2020 Jul 07;:1-8 Authors: Muhammad T, Dhanani R, Mohtasham S, Hussain M, Faisal M, Malik KI, Jamshed A, Hussain R Abstract Background: Incidence of thyroid gland invasion in advanced laryngeal cancers is low. Ipsilateral or total thyroidectomy along...
Larynx
Wed Jul 08, 2020 17:45
Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease.
Related Articles Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease. J Otolaryngol Head Neck Surg. 2020 Jul 06;49(1):46 Authors: Song JS, Vallance P, Biron V, Jeffery CC Abstract BACKGROUND: With an increase in the incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) and more favourable survival outcomes, there is now a population...
Larynx
Wed Jul 08, 2020 13:41
Multiple symmetric lipomatosis with secondary laryngeal obstruction: A case report.
Related Articles Multiple symmetric lipomatosis with secondary laryngeal obstruction: A case report. Medicine (Baltimore). 2020 Jul 02;99(27):e21014 Authors: Cui Y, Cui X, Gao S, Zhu Z, Yin W Abstract INTRODUCTION: Multiple symmetric lipomatosis (MSL) is an uncommon medical condition characterized by symmetric fat accumulation mainly in the neck and other upper body regions. The involvement of the larynx is rare according to the literature,...
Larynx
Wed Jul 08, 2020 13:41
Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis.
Related Articles Safety and clinical activity of PD-L1 blockade in patients with aggressive recurrent respiratory papillomatosis. J Immunother Cancer. 2019 05 03;7(1):119 Authors: Allen CT, Lee S, Norberg SM, Kovalovsky D, Ye H, Clavijo PE, Hu-Lieskovan S, Schlegel R, Schlom J, Strauss J, Gulley JL, Trepel J, Hinrichs CS Abstract BACKGROUND: Recurrent respiratory papillomatosis (RRP) is a human papillomavirus (HPV)-driven disorder that causes...
Larynx
Wed Jul 08, 2020 13:41
When a mimicker wears strange faces: description of an osteogenic melanoma arising within an ovarian teratoma with focus on its late peritoneal relapse.
Related Articles When a mimicker wears strange faces: description of an osteogenic melanoma arising within an ovarian teratoma with focus on its late peritoneal relapse. Eur Rev Med Pharmacol Sci. 2020 Jun;24(12):6569-6575 Authors: Angelico G, Santoro A, Inzani F, Martini M, D'Alessandris N, Spadola S, Valente M, Arciuolo D, Sfregola S, Mule' A, Scambia G, Zannoni GF Abstract Secondary malignancies arising within mature teratomas are a rare...
Rare Cancers
Wed Jul 08, 2020 14:47
Pitfalls in Challenging Thyroid Tumors: Emphasis on Differential Diagnosis and Ancillary Biomarkers.
Related Articles Pitfalls in Challenging Thyroid Tumors: Emphasis on Differential Diagnosis and Ancillary Biomarkers. Endocr Pathol. 2020 Jul 06;: Authors: Cameselle-Teijeiro JM, Eloy C, Sobrinho-Simões M Abstract Thyroid pathology encompasses a heterogenous group of clinicopathological entities including rare and diagnostically challenging neoplasms. The review is focused on morphological, immunohistochemical, and molecular features of rare...
Rare Cancers
Wed Jul 08, 2020 14:47
Cause of Mortality After Radical Prostatectomy and the Impact of Comorbidity in Men with Prostate Cancer: A Multi-Institutional Study in Korea.
Related Articles Cause of Mortality After Radical Prostatectomy and the Impact of Comorbidity in Men with Prostate Cancer: A Multi-Institutional Study in Korea. Cancer Res Treat. 2020 Jul 03;: Authors: Pak S, You D, Jeong IG, Lee DE, Kim SH, Joung JY, Lee KH, Hong JH, Kim CS, Ahn H Abstract Purpose: To examine the causes of death in Korean patients who underwent radical prostatectomy for prostate cancer and investigate the relationship between...
Rare Cancers
Wed Jul 08, 2020 14:47
Clinicopathological study of blue nevi of the gastrointestinal (GI) tract: first case series.
Related Articles Clinicopathological study of blue nevi of the gastrointestinal (GI) tract: first case series. J Clin Pathol. 2020 Jul 06;: Authors: Assarzadegan N, Salimian K, Hutchings D, Windon AL, Voltaggio L, Montgomery EA Abstract AIM: Blue nevus (BN) is a benign melanocytic proliferation that is typically cutaneous. Extracutaneous BN is infrequent and is reported in the mucosa of various organs. Gastrointestinal (GI) tract BN is rare....
Rare Cancers
Wed Jul 08, 2020 14:47
Tenosynovial giant cell tumor of the suboccipital region - A rare, benign neoplasm in this location.
Related Articles Tenosynovial giant cell tumor of the suboccipital region - A rare, benign neoplasm in this location. J Clin Neurosci. 2020 Jul 03;: Authors: Singh R, Stienen MN, Ganjoo K, Kolahi KS, Cayrol R, Charville GW, Born DE, Zygourakis CC Abstract Tenosynovial giant cell tumors (TGCTs) are benign neoplasms that arise from the synovium of tendon sheaths, bursae, and joints. We report a rare presentation of TGCT involving the suboccipital...
Rare Cancers
Wed Jul 08, 2020 13:40
Paraneoplastic Musculoskeletal Syndromes.
Related Articles Paraneoplastic Musculoskeletal Syndromes. Rheum Dis Clin North Am. 2020 Aug;46(3):577-586 Authors: Khan F, Kleppel H, Meara A Abstract Paraneoplastic syndromes are rare diseases caused by malignancies through means other than mass effect or metastasis. Paraneoplastic phenomena can be the first sign of cancer and can be fatal. Paraneoplastic rheumatic syndromes can occur with hematologic cancers, lymphoproliferative disease,...
Rare Cancers
Wed Jul 08, 2020 13:40
Renal Hemangioblastoma with Mixed Mullerian tumour of endometrium: A tale of two rare primary tumours.
Related Articles Renal Hemangioblastoma with Mixed Mullerian tumour of endometrium: A tale of two rare primary tumours. World J Surg Oncol. 2020 Jul 06;18(1):154 Authors: Setia A, Kumar D, Bains L, Sharma P, Tempe A, Mallya V Abstract INTRODUCTION: Renal hemangioblastoma (RH) is a very rare benign tumour. Hemangioblastoma most commonly occurs in the central nervous system (CNS), and only few cases of RH have been reported as they occur most...
Rare Cancers
Wed Jul 08, 2020 13:40
Sarcoma epidemiology and cancer-related hospitalisation in Western Australia from 1982 to 2016: a descriptive study using linked administrative data.
Related Articles Sarcoma epidemiology and cancer-related hospitalisation in Western Australia from 1982 to 2016: a descriptive study using linked administrative data. BMC Cancer. 2020 Jul 06;20(1):625 Authors: Wright CM, Halkett G, Carey Smith R, Moorin R Abstract BACKGROUND: Sarcomas are a heterogeneous group of malignancies arising from mesenchymal cells. Epidemiological studies on sarcoma from Australia are lacking, as previous studies have...
Rare Cancers
Wed Jul 08, 2020 13:40
Basal cell carcinoma misdiagnosed as trichoepithelioma.
Related Articles Basal cell carcinoma misdiagnosed as trichoepithelioma. Arch Craniofac Surg. 2020 Jun;21(3):202-205 Authors: Wee SJ, Park MC, Chung CM Abstract Trichoepithelioma is a benign hair follicle tumor that can undergo malignant transformation into basal cell carcinoma in rare cases. Due to the similar clinical and histological features of trichoepithelioma and basal cell carcinoma, distinguishing between these types of tumors can be...
Rare Cancers
Wed Jul 08, 2020 13:40
Sertoli-Leydig cell tumor in two siblings with DICER1 syndrome: A case report and literature review.
Related Articles Sertoli-Leydig cell tumor in two siblings with DICER1 syndrome: A case report and literature review. Medicine (Baltimore). 2020 Jul 02;99(27):e20806 Authors: Zhang Y, Ren M, Hong Y, Zhong Y, Cong X, Chen C, Liu Z, Man Y, Yang L Abstract RATIONALE: DICER1 syndrome is an autosomal-dominant tumor predisposition syndrome associated with numerous cancerous and noncancerous conditions. The most common sex cord-stromal tumor associated...
Rare Cancers
Wed Jul 08, 2020 13:40
Management of adenoid cystic carcinoma of the head and neck: a single-institute study with over 25-year follow-up.
Related Articles Management of adenoid cystic carcinoma of the head and neck: a single-institute study with over 25-year follow-up. Head Face Med. 2020 Jul 02;16(1):14 Authors: Ishida E, Ogawa T, Rokugo M, Ishikawa T, Wakamori S, Ohkoshi A, Usubuchi H, Higashi K, Ishii R, Nakanome A, Katori Y Abstract BACKGROUND: Adenoid cystic carcinoma is a rare malignant tumor arising from exocrine glands such as the major and minor salivary glands of the...
Rare Cancers
Wed Jul 08, 2020 13:40
Perforated Ileal GIST Associated with Meckel Diverticulum - A Rare Pathological Entity of Surgical Acute Abdomen.
Related Articles Perforated Ileal GIST Associated with Meckel Diverticulum - A Rare Pathological Entity of Surgical Acute Abdomen. Chirurgia (Bucur). 2020 May-Jun;115(3):404-409 Authors: Şerban C, Constantin GB, Firescu D, Rebegea L, Manole CP, Truş C, Voicuş D, Bîrlă R Abstract Introduction: The GIST tumors are very rare entities ( 1% of all tumors). They originate in the Cajal interstitial cells, which are part of the autonomic nervous system...
Rare Cancers
Wed Jul 08, 2020 13:40
Bilateral pediatric pial arteriovenous fistulas accompanying a giant arachnoid cyst with torticollis: A case report.
Related Articles Bilateral pediatric pial arteriovenous fistulas accompanying a giant arachnoid cyst with torticollis: A case report. Medicine (Baltimore). 2020 Jun 26;99(26):e20991 Authors: Li J, Wang T, Richard SA, Zhang C, Xie X, Wang C Abstract RATIONALE: Pial arteriovenous fistula (PAVF) occurs when intracranial arteries communicate directly with veins. PAVFs are very rare congenital vascular lesions that are commonly seen in infants and...
Rare Cancers
Wed Jul 08, 2020 13:40
Primary signet ring cell carcinoma with tubular adenoma of the rectum: A case report and a review of the literature.
Related Articles Primary signet ring cell carcinoma with tubular adenoma of the rectum: A case report and a review of the literature. Medicine (Baltimore). 2020 Jun 26;99(26):e20985 Authors: Yang YP, Yu LY, Shi J, Li JN, Wang XY, Liu TJ Abstract RATIONALE: Among the various forms of colorectal carcinomas, primary signet ring cell carcinoma (SRCC) of rectum is infrequent. Primary SRCC with adenoma is even rarer. Due to its low morbidity and...
Rare Cancers
Wed Jul 08, 2020 13:40
Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review.
Related Articles Pulmonary sclerosing pneumocytoma in an 18-year-old male patient: A case report and literature review. Medicine (Baltimore). 2020 Jun 26;99(26):e20869 Authors: Le HY, Pham DP, Nguyen KT, Hoang VA, Trinh TS, Do Q Abstract RATIONALE: Pulmonary sclerosing pneumocytoma (PSP) is a rare benign tumor of the lung, mostly presented in Asian middle-aged women. Initially, it was considered as a vascular origin tumor, but then research...
Rare Cancers
Wed Jul 08, 2020 13:40
Atypical polypoid adenomyoma follow-up and management: Systematic review of case reports and series and meta-analysis.
Related Articles Atypical polypoid adenomyoma follow-up and management: Systematic review of case reports and series and meta-analysis. Medicine (Baltimore). 2020 Jun 26;99(26):e20491 Authors: Biasioli A, Londero AP, Orsaria M, Scrimin F, Mangino FP, Bertozzi S, Mariuzzi L, Cagnacci A Abstract BACKGROUND: Atypical polypoid adenomyoma (APA) is a rare uterine tumor typically found in fertile age and associated with infertility. Among young nullipara...
Rare Cancers
Wed Jul 08, 2020 13:40
Rare case of Richter's syndrome localization in liver and thyroid of a patient with a chronic lymphocytic leukemia (CLL) - Case report and literature.
Related Articles Rare case of Richter's syndrome localization in liver and thyroid of a patient with a chronic lymphocytic leukemia (CLL) - Case report and literature. Ann Agric Environ Med. 2020 Mar 17;27(1):160-164 Authors: Wąsik-Szczepanek E, Szymczyk A, Szczepanek D, Grywalska E, Szumiło J, Trojanowski P, Czabak O, Hus M Abstract Richter's syndrome (RS) is a rare complication in which chronic lymphocytic leukaemia (CLL) or small lymphocytic...
Rare Cancers
Wed Jul 08, 2020 13:40
[Synovial sarcoma - a rare and highly malignant, tumor with an ambiguous clinical picture at times].
Related Articles [Synovial sarcoma - a rare and highly malignant, tumor with an ambiguous clinical picture at times]. Lakartidningen. 2020 01 16;117: Authors: Brosjö O, Skogman R Abstract A characteristic feature of soft tissue sarcomas is the absence of alarm symptoms such as pain or abnormal laboratory findings. We present two patients where the diagnostic difficulties delayed the definitive diagnosis, in one case with lethal outcome. The...
Rare Cancers
Wed Jul 08, 2020 13:40
A Blue-Gray Macule on the Back: Answer.
Related Articles A Blue-Gray Macule on the Back: Answer. Am J Dermatopathol. 2020 Jan;42(1):65 Authors: Aderibigbe O, Groft-MacFarlane C, Chu EY PMID: 31880637 [PubMed - indexed for MEDLINE]
Rare Cancers
Wed Jul 08, 2020 13:40
Bortezomib- and Lenalidomide-Based Treatment of Refractory Plasmablastic Lymphoma.
Related Articles Bortezomib- and Lenalidomide-Based Treatment of Refractory Plasmablastic Lymphoma. Oncol Res Treat. 2020;43(3):112-116 Authors: Ando K, Imaizumi Y, Kobayashi Y, Niino D, Hourai M, Sato S, Sawayama Y, Hata T, Ohshima K, Miyazaki Y Abstract INTRODUCTION: Plasmablastic lymphoma (PBL) is a rare variant of diffuse large B-cell lymphoma for which no optimal treatment has been established and prognosis remains poor. Here, we describe...
Rare Cancers
Wed Jul 08, 2020 13:40
Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients.
Related Articles Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients. J Vis Exp. 2019 11 19;(153): Authors: Bhagirath D, Dahiya R, Majid S, Tabatabai ZL, Saini S Abstract Ablation of androgen receptor (AR) signaling by androgen deprivation is the goal of the first line of therapy for prostate cancer that initially results in cancer regression. However, in...
Rare Cancers
Wed Jul 08, 2020 13:40
A novel germline variant in the DOT1L gene co-segregating in a Dutch family with a history of melanoma.
Related Articles A novel germline variant in the DOT1L gene co-segregating in a Dutch family with a history of melanoma. Melanoma Res. 2019 12;29(6):582-589 Authors: Salgado C, Kwesi-Maliepaard EM, Jochemsen AG, Visser M, Harland M, van Leeuwen F, van Doorn R, Gruis N Abstract A proportion of patients diagnosed with melanoma has a positive family history. Despite increasing knowledge on the genes responsible for familial clustering, the genetic...
Rare Cancers
Wed Jul 08, 2020 13:40
Extramammary Paget Disease: A Review of the Literature-Part I: History, Epidemiology, Pathogenesis, Presentation, Histopathology, and Diagnostic Work-up.
Related Articles Extramammary Paget Disease: A Review of the Literature-Part I: History, Epidemiology, Pathogenesis, Presentation, Histopathology, and Diagnostic Work-up. Dermatol Surg. 2020 02;46(2):151-158 Authors: Morris CR, Hurst EA Abstract BACKGROUND: Extramammary Paget disease (EMPD) is a rare malignancy with unclear pathophysiology that occurs predominantly on apocrine rich skin. Surgery is the treatment of choice; however, procedures...
Rare Cancers
Wed Jul 08, 2020 13:40
Cutaneous Leiomyosarcoma: A SEER Database Analysis.
Related Articles Cutaneous Leiomyosarcoma: A SEER Database Analysis. Dermatol Surg. 2020 02;46(2):159-164 Authors: Sandhu N, Sauvageau AP, Groman A, Bogner PN Abstract BACKGROUND: Cutaneous leiomyosarcoma is a rare dermal neoplasm usually arising from the pilar smooth muscle. It is considered a relatively indolent neoplasm, and there is debate whether designation as sarcoma is appropriate. Owing to some conflicting data in the literature, however,...
Rare Cancers
Wed Jul 08, 2020 13:40
Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif.
Related Articles Sporadic and endemic Burkitt lymphoma have frequent FOXO1 mutations but distinct hotspots in the AKT recognition motif. Blood Adv. 2019 07 23;3(14):2118-2127 Authors: Zhou P, Blain AE, Newman AM, Zaka M, Chagaluka G, Adlar FR, Offor UT, Broadbent C, Chaytor L, Whitehead A, Hall A, O'Connor H, Van Noorden S, Lampert I, Bailey S, Molyneux E, Bacon CM, Bomken S, Rand V Abstract FOXO1 has an oncogenic role in adult germinal center-derived...
Rare Cancers
Wed Jul 08, 2020 13:40
Real world data as a key element in precision medicine for lymphoid malignancies: potentials and pitfalls.
Related Articles Real world data as a key element in precision medicine for lymphoid malignancies: potentials and pitfalls. Br J Haematol. 2019 08;186(3):409-419 Authors: El-Galaly TC, Cheah CY, Villa D Abstract Molecular genetic studies of lymphoma have led to refinements in disease classification in the most recent World Health Organization update. Nevertheless, a 'one-size-fits-most' treatment strategy based on morphology remains widely...
Rare Cancers
Wed Jul 08, 2020 13:40

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