Antibiotics, Vol. 9, Pages 391: Antimicrobial Spectrum of Titroleane™: A New Potent Anti-Infective Agent Antibiotics doi: 10.3390/antibiotics9070391 Authors: Bianca Johansen Raphaël E. Duval Jean-Christophe Sergere Tea Tree oil (TTO) is well known for its numerous good properties but might be also irritating or toxic when used topically or ingested, thus limiting the number of possible applications in Humans. The aim of the study was to characterize the antimicrobial spectrum as...
Wed Jul 08, 2020 03:00
Antibiotics, Vol. 9, Pages 390: Antimicrobial and Efflux Pump Inhibitory Activity of Carvotacetones from Sphaeranthus africanus Against Mycobacteria Antibiotics doi: 10.3390/antibiotics9070390 Authors: Huyen Thi Tran Julia Solnier Eva-Maria Pferschy-Wenzig Olaf Kunert Liam Martin Sanjib Bhakta Loi Huynh Tri Minh Le Rudolf Bauer Franz Bucar Carvotacetones (1–7) isolated from Sphaeranthus africanus were screened for their antimycobacterial and efflux...
Wed Jul 08, 2020 03:00
Antibiotics, Vol. 9, Pages 389: Patterns of Antibiotic Prescription in Colombia: Are There Differences between Capital Cities and Municipalities? Antibiotics doi: 10.3390/antibiotics9070389 Authors: Jorge Enrique Machado-Alba Luis Fernando Valladales-Restrepo Andrés Gaviria-Mendoza Manuel Enrique Machado-Duque Albert Figueras The use of antibiotics is the most important modifiable risk factor for the development of microorganism resistance. A cross-sectional study of outpatients...
Wed Jul 08, 2020 03:00
Antioxidants, Vol. 9, Pages 597: The Role of Oxidative Stress in Parkinson’s Disease Antioxidants doi: 10.3390/antiox9070597 Authors: Chang Chen Parkinson’s disease (PD) is caused by progressive neurodegeneration of dopaminergic (DAergic) neurons with abnormal accumulation of α-synuclein in substantia nigra (SN). Studies have suggested the potential involvement of dopamine, iron, calcium, mitochondria and neuroinflammation in contributing to overwhelmed oxidative...
Wed Jul 08, 2020 03:00
Atmosphere, Vol. 11, Pages 730: The Spiderweb Structure of Stratocumulus Clouds Atmosphere doi: 10.3390/atmos11070730 Authors: Georgios Matheou Anthony B. Davis João Teixeira Stratocumulus clouds have a distinctive structure composed of a combination of lumpy cellular structures and thin elongated regions, resembling canyons or slits. The elongated slits are referred to as “spiderweb” structure to emphasize their interconnected nature. Using very high resolution...
Wed Jul 08, 2020 03:00
Atmosphere, Vol. 11, Pages 729: Impact of AERI Temperature and Moisture Retrievals on the Simulation of a Central Plains Severe Convective Weather Event Atmosphere doi: 10.3390/atmos11070729 Authors: Lewis Wagner Otkin Jones In this study, bias-corrected temperature and moisture retrievals from the Atmospheric Emitted Radiance Interferometer (AERI) were assimilated using the Data Assimilation Research Testbed ensemble adjustment Kalman filter to assess their impact on Weather...
Wed Jul 08, 2020 03:00
Atmosphere, Vol. 11, Pages 728: Fast Warming Has Accelerated Snow Cover Loss during Spring and Summer across the Northern Hemisphere over the Past 52 Years (1967–2018) Atmosphere doi: 10.3390/atmos11070728 Authors: Xuejiao Wu Yongping Shen Wei Zhang Yinping Long With snow cover changing worldwide in several worrisome ways, it is imperative to determine both the variability in snow cover in greater detail and its relationship with ongoing climate change. Here, we used the satellite-based...
Wed Jul 08, 2020 03:00
Atmosphere, Vol. 11, Pages 727: UV-Index Climatology for Europe Based on Satellite Data Atmosphere doi: 10.3390/atmos11070727 Authors: Ronja Vitt Gudrun Laschewski Alkiviadis F. Bais Henri Diémoz Ilias Fountoulakis Anna-Maria Siani Andreas Matzarakis The UV-Index (UVI) is aimed at the prevention of skin cancer as well as other negative implications of ultraviolet radiation exposure. In order to support health related applications, assessments and planning that rely...
Wed Jul 08, 2020 03:00
Beverages, Vol. 6, Pages 44: Coffee Flavor: A Review Beverages doi: 10.3390/beverages6030044 Authors: Seninde Chambers Flavor continues to be a driving force for coffee’s continued growth in the beverage market today. Studies have identified the sensory aspects and volatile and non-volatile compounds that characterize the flavor of different coffees. This review discusses aspects that influence coffee drinking and aspects such as environment, processing, and preparation...
Wed Jul 08, 2020 03:00
Bioengineering, Vol. 7, Pages 73: Bioreactor Parameters for Microcarrier-Based Human MSC Expansion under Xeno-Free Conditions in a Vertical-Wheel System Bioengineering doi: 10.3390/bioengineering7030073 Authors: Josephine Lembong Robert Kirian Joseph D. Takacs Timothy R. Olsen Lye Theng Lock Jon A. Rowley Tabassum Ahsan Human mesenchymal stem/stromal cells (hMSCs) have been investigated and proven to be a well-tolerated, safe therapy for a variety of indications, as...
Wed Jul 08, 2020 03:00
Biology, Vol. 9, Pages 159: Assessment of Cytocompatibility and Anti-Inflammatory (Inter)Actions of Genipin-Crosslinked Chitosan Powders Biology doi: 10.3390/biology9070159 Authors: Simona Dimida Matteo Santin Tiziano Verri Amilcare Barca Christian Demitri Chitosan is a polysaccharide commonly used, together with its derivatives, in the preparation of hydrogel formulations, scaffolds and films for tissue engineering applications. Chitosan can be used as such, but it is commonly...
Wed Jul 08, 2020 03:00
Biology, Vol. 9, Pages 157: Role of B Cell Lymphoma 2 in the Regulation of Liver Fibrosis in miR-122 Knockout Mice Biology doi: 10.3390/biology9070157 Authors: Kun-Yu Teng Juan M. Barajas Peng Hu Samson T. Jacob Kalpana Ghoshal MicroRNA-122 (miR-122) has been identified as a marker of various liver injuries, including hepatitis- virus-infection-, alcoholic-, and non-alcoholic steatohepatitis (NASH)-induced liver fibrosis. Here, we report that the extracellular miR-122 from...
Wed Jul 08, 2020 03:00
Biology, Vol. 9, Pages 158: Understanding the Morpho-Anatomical, Physiological, and Functional Response of Sweet Basil to Isosmotic Nitrate to Chloride Ratios Biology doi: 10.3390/biology9070158 Authors: Corrado Formisano De Micco Pannico Giordano El-Nakhel Chiaiese Sacchi Rouphael Sweet basil (Ocimum basilicum L.) is a leafy green with a short-production cycle that is emerging as a model species among aromatic plants. Modulating the mineral composition...
Wed Jul 08, 2020 03:00
Biomedicines, Vol. 8, Pages 201: Mediterranean Diet as a Tool to Combat Inflammation and Chronic Diseases. An Overview Biomedicines doi: 10.3390/biomedicines8070201 Authors: Christina Tsigalou Theocharis Konstantinidis Afroditi Paraschaki Elisavet Stavropoulou Chrissoula Voidarou Eugenia Bezirtzoglou Since ancient times, the quality of nourishment is a milestone for the maintenance of health and as it is stated ‘prevention is better than cure’, amongst...
Wed Jul 08, 2020 03:00
Biomedicines, Vol. 8, Pages 200: Secreted Factors from Keloid Keratinocytes Modulate Collagen Deposition by Fibroblasts from Normal and Fibrotic Tissue: A Pilot Study Biomedicines doi: 10.3390/biomedicines8070200 Authors: Mansour A. Alghamdi Laith N. AL-Eitan Andrew Stevenson Nutan Chaudhari Nicole Hortin Hilary J. Wallace Patricia L. Danielsen Mitali Manzur Fiona M. Wood Mark W. Fear Interactions between keratinocytes and fibroblasts in the skin layers are...
Wed Jul 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1013: Metabolic Roles of Plant Mitochondrial Carriers Biomolecules doi: 10.3390/biom10071013 Authors: Alisdair R. Fernie João Henrique F. Cavalcanti Adriano Nunes-Nesi Mitochondrial carriers (MC) are a large family (MCF) of inner membrane transporters displaying diverse, yet often redundant, substrate specificities, as well as differing spatio-temporal patterns of expression; there are even increasing examples of non-mitochondrial subcellular localization....
Wed Jul 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1014: The Addition of a Synthetic LPS-Targeting Domain Improves Serum Stability While Maintaining Antimicrobial, Antibiofilm, and Cell Stimulating Properties of an Antimicrobial Peptide Biomolecules doi: 10.3390/biom10071014 Authors: Anna Maystrenko Yulong Feng Nadeem Akhtar Julang Li Multi-drug resistant (MDR) bacteria and their biofilms are a concern in veterinary and human medicine. Protegrin-1 (PG-1), a potent antimicrobial peptide (AMP) with...
Wed Jul 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1012: Nerve Segmentation with Deep Learning from Label-Free Endoscopic Images Obtained Using Coherent Anti-Stokes Raman Scattering Biomolecules doi: 10.3390/biom10071012 Authors: Naoki Yamato Mana Matsuya Hirohiko Niioka Jun Miyake Mamoru Hashimoto Semantic segmentation with deep learning to extract nerves from label-free endoscopic images obtained using coherent anti-Stokes Raman scattering (CARS) for nerve-sparing surgery is described. We developed...
Wed Jul 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1011: Cold Atmospheric Plasma Is a Potent Tool to Improve Chemotherapy in Melanoma In Vitro and In Vivo Biomolecules doi: 10.3390/biom10071011 Authors: Mina Alimohammadi Monireh Golpur Farshad Sohbatzadeh Seyedehniaz Hadavi Sander Bekeschus Haleh Akhavan Niaki Reza Valadan Alireza Rafiei Malignant melanoma is a devastating disease. Because of its aggressiveness, it also serves as a model tumor for investigating novel therapeutic avenues....
Wed Jul 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1010: Molecular Insights of Copper Sulfate Exposure-Induced Nephrotoxicity: Involvement of Oxidative and Endoplasmic Reticulum Stress Pathways Biomolecules doi: 10.3390/biom10071010 Authors: Chongshan Dai Qiangqiang Liu Daowen Li Gaurav Sharma Jianli Xiong Xilong Xiao The precise pathogenic mechanism in Cu exposure-cause nephrotoxicity remains unclear. This study investigated the underlying molecular mechanism of copper sulfate (CuSO4)-induced...
Wed Jul 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1009: Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity Biomolecules doi: 10.3390/biom10071009 Authors: Indre Kucinskaite-Kodze Martynas Simanavicius Justas Dapkunas Milda Pleckaityte Aurelija Zvirbliene The pathogenicity of many bacteria, including Streptococcus pneumoniae, depends on pore-forming toxins (PFTs) that cause host cell lysis by forming large pores in cholesterol-containing...
Wed Jul 08, 2020 03:00
Biosensors, Vol. 10, Pages 75: A Self-Powered Biosensor for Monitoring Maximal Lactate Steady State in Sport Training Biosensors doi: 10.3390/bios10070075 Authors: Yupeng Mao Wen Yue Tianming Zhao MaiLun Shen Bing Liu Song Chen A self-powered biosensor for monitoring the maximal lactate steady state (MLSS) during exercise has been developed for intelligently assisting training system. It has been presented to create poly (vinylidene fluoride) (PVDF)/Tetrapod-shaped ZnO...
Wed Jul 08, 2020 03:00
Brain Sciences, Vol. 10, Pages 435: Morphofunctional Alterations of the Hypothalamus and Social Behavior in Autism Spectrum Disorders Brain Sciences doi: 10.3390/brainsci10070435 Authors: Andrea Caria Luciana Ciringione Simona de Falco An accumulating body of evidence indicates a tight relationship between the endocrine system and abnormal social behavior. Two evolutionarily conserved hypothalamic peptides, oxytocin and arginine-vasopressin, because of their extensively documented...
Wed Jul 08, 2020 03:00
Brain Sciences, Vol. 10, Pages 434: A Novel Clinical Research Modality for Enrolling Diverse Participants Using a Diverse Team Brain Sciences doi: 10.3390/brainsci10070434 Authors: Phoebe Lay Tapasvini Paralkar Syed Hadi Ahmed Minha Ghani Sara Muneer Ramsha Jinnah Carolyn Chen Jack Zeitz Alejandra Nitsch Nico Osier The advancement of the pediatric traumatic brain injury (TBI) knowledge base requires biospecimens and data from large samples. This study seeks...
Wed Jul 08, 2020 03:00
Brain Sciences, Vol. 10, Pages 433: Influence of Voluntary Contraction Level, Test Stimulus Intensity and Normalization Procedures on the Evaluation of Short-Interval Intracortical Inhibition Brain Sciences doi: 10.3390/brainsci10070433 Authors: Cécilia Neige Sidney Grosprêtre Alain Martin Florent Lebon Short-interval intracortical inhibition (SICI) represents an inhibitory phenomenon acting at the cortical level. However, SICI estimation is based on the amplitude of a motor-evoked...
Wed Jul 08, 2020 03:00
Brain Sciences, Vol. 10, Pages 432: Sex Differences in Work-Stress Memory Bias and Stress Hormones Brain Sciences doi: 10.3390/brainsci10070432 Authors: Dumont Marin Lupien Juster Mental health problems related to chronic stress in workers appear to be sex-specific. Psychosocial factors related to work–life balance partly explain these sex differences. In addition, physiological markers of stress can provide critical information on the mechanisms explaining how...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1845: Non-Coding RNA Editing in Cancer Pathogenesis Cancers doi: 10.3390/cancers12071845 Authors: Giulia Romano Michela Saviana Patricia Le Howard Li Lavender Micalo Giovanni Nigita Mario Acunzo Patrick Nana-Sinkam In the last two decades, RNA post-transcriptional modifications, including RNA editing, have been the subject of increasing interest among the scientific community. The efforts of the Human Genome Project combined with the development...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1839: A Concise Paradigm on Radical Hysterectomy: The Comprehensive Anatomy of Parametrium, Paracolpium and the Pelvic Autonomic Nerve System and Its Surgical Implication Cancers doi: 10.3390/cancers12071839 Authors: Mustafa Zelal Muallem Thomas Jöns Nadja Seidel Jalid Sehouli Yasser Diab Denis Querleu The current understanding of radical hysterectomy is more centered on the uterus and little is discussed regarding the resection of the vaginal cuff...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1843: Identification of the Novel Oncogenic Role of SAAL1 and Its Therapeutic Potential in Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12071843 Authors: Chu Tung Tsai Shen Chan Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide, affecting over 700,000 people per year. The treatment effect in advanced HCC is still disappointing and prognosis of advanced HCC remains poor. Hence, to find more effective therapeutic...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1842: Coding of Glioblastoma Progression and Therapy Resistance through Long Noncoding RNAs Cancers doi: 10.3390/cancers12071842 Authors: Alja Zottel Neja Šamec Alja Videtič Videtič Paska Ivana Jovčevska Glioblastoma is the most aggressive and lethal primary brain malignancy, with an average patient survival from diagnosis of 14 months. Glioblastoma also usually progresses as a more invasive phenotype after initial treatment. A major step forward in...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1838: Regulation of DNA Damage Response and Homologous Recombination Repair by microRNA in Human Cells Exposed to Ionizing Radiation Cancers doi: 10.3390/cancers12071838 Authors: Magdalena Szatkowska Renata Krupa Ionizing radiation may be of both artificial and natural origin and causes cellular damage in living organisms. Radioactive isotopes have been used significantly in cancer therapy for many years. The formation of DNA double-strand breaks (DSBs) is...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1841: Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe Cancers doi: 10.3390/cancers12071841 Authors: David J. Pinato Alvin J. X. Lee Federica Biello Elia Seguí Juan Aguilar-Company Anna Carbó Riccardo Bruna Mark Bower Gianpiero Rizzo Sarah Benafif Carme Carmona Neha Chopra Claudia Andrea Cruz Francesca D’Avanzo Joanne S. Evans Myria...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1840: Transitions of Liver and Biliary Enzymes during Proton Beam Therapy for Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12071840 Authors: Taisuke Sumiya Masashi Mizumoto Yoshiko Oshiro Keiichiro Baba Motohiro Murakami Shosei Shimizu Masatoshi Nakamura Yuichi Hiroshima Toshiki Ishida Takashi Iizumi Takashi Saito Haruko Numajiri Kei Nakai Toshiyuki Okumura Hideyuki Sakurai Proton beam therapy (PBT) is a curative...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1844: TIAM2S Mediates Serotonin Homeostasis and Provokes a Pro-Inflammatory Immune Microenvironment Permissive for Colorectal Tumorigenesis Cancers doi: 10.3390/cancers12071844 Authors: Ya-Ling Chan Wei-Chung Lai Jia-Shing Chen Joseph Ta-Chien Tseng Pei-Chin Chuang Jonathan Jou Chung-Ta Lee H. Sunny Sun The short isoform of human TIAM2 has been shown to promote proliferation and invasion in various cancer cells. However, the roles of TIAM2S...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1836: Tumor-Targeting Peptides: The Functional Screen of Glioblastoma Homing Peptides to the Target Protein FABP3 (MDGI) Cancers doi: 10.3390/cancers12071836 Authors: Abiodun Ayo Eduard Figueras Thomas Schachtsiek Mazlum Budak Norbert Sewald Pirjo Laakkonen We recently identified the glioblastoma homing peptide CooP (CGLSGLGVA) using in vivo phage display screen. The mammary-derived growth inhibitor (MDGI/FABP3) was identified as its interacting...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1835: HLA Evolutionary Divergence as a Prognostic Marker for AML Patients Undergoing Allogeneic Stem Cell Transplantation Cancers doi: 10.3390/cancers12071835 Authors: Malte Roerden Annika Nelde Jonas S. Heitmann Reinhild Klein Hans-Georg Rammensee Wolfgang A. Bethge Juliane S. Walz The diversity of human leukocyte antigens (HLAs) enables the presentation of immense repertoires of peptides, including tumor-associated antigens (TAAs). As a surrogate...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1833: Mechanisms of Androgen Receptor Agonist- and Antagonist-Mediated Cellular Senescence in Prostate Cancer Cancers doi: 10.3390/cancers12071833 Authors: Miriam Kokal Kimia Mirzakhani Thanakorn Pungsrinont Aria Baniahmad The androgen receptor (AR) plays a leading role in the control of prostate cancer (PCa) growth. Interestingly, structurally different AR antagonists with distinct mechanisms of antagonism induce cell senescence, a mechanism that inhibits...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1834: Comorbidity Risk Score in Association with Cancer Incidence: Results from a Cancer Screenee Cohort Cancers doi: 10.3390/cancers12071834 Authors: Hoang Lee Kim The combined effects of comorbidities can cause cancer incidence, while the effects of individual conditions, alone, might not. This study was conducted to investigate the joint impact of comorbidities on cancer incidence. The dietary score for energy-adjusted intake was calculated by applying...
Wed Jul 08, 2020 03:00
Cancers, Vol. 12, Pages 1837: Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a Cancers doi: 10.3390/cancers12071837 Authors: Maxim Bychkov Mikhail Shulepko Dmitry Osmakov Yaroslav Andreev Anastasia Sudarikova Valeria Vasileva Marat S. Pavlyukov Yaroslav A. Latyshev Alexander A. Potapov Mikhail Kirpichnikov Zakhar O. Shenkarev Ekaterina Lyukmanova Gliomas are fast growing and highly invasive brain tumors,...
Wed Jul 08, 2020 03:00
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