Abstract Stem cell exhaustion plays a major role in the ageing of different tissues. Similarly, in vitro cell ageing during expansion prior to their use in regenerative medicine can severely compromise stem cell quality through progressive declines in differentiation and growth capacity. We utilized non-destructive multispectral assessment of native cell autofluorescence to investigate the metabolic mechanisms of in vitro mesenchymal stem cell (MSC) ageing in human bone marrow...
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20 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human homeostasis These pubmed results were generated on 2020/08/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 12, 2020 16:51
69 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2020/08/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 12, 2020 16:58
2019 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 12, 2020 17:16
2019 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2020/08/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 12, 2020 13:18
A highly-effective and widely available vaccine will likely be necessary to get the COVID-19 pandemic under control, save lives, and return to normal life. But performing proper due diligence when it comes to testing will save lives, too. (Pixabay /)The race to develop a safe and effective vaccine against the novel coronavirus has drawn the attention of virologists and other health researchers the world over. As cases continue to climb around the globe, a vaccine remains amongst the most promising...
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Many factors play into the effectiveness of ventilation systems on COVID-19. (Meritt Thomas/Unsplash/)Shelly Miller is a professor of mechanical engineering at the University of Colorado Boulder. This story originally featured on The Conversation.The vast majority of SARS-CoV-2 transmission occurs indoors, most of it from the inhalation of airborne particles that contain the coronavirus. The best way to prevent the virus from spreading in a home or business would be to simply keep infected people...
Wed Aug 12, 2020 23:00
Flooding during Hurricane Harvey (andrewtheshrew/Pixabay/)Hurricanes can be made exponentially worse by whatever lies in their path. Unfortunately, that’s often the toxic waste of some of the most extractive, pollutive industries.Take Hurricane Florence, for instance. The storm’s intense downpour triggered the spill of coal ash, the arsenic-laced substance that remains after burning coal, from a coal-fired power plant in North Carolina. Hurricane Harvey’s torrential waters also quickly turned toxic...
Wed Aug 12, 2020 22:03
Dancing finally gets the recognition it deserves as a full-fledged workout. (Stan Horaczek/)Apple is about to give its watchOS operating system the major update that we first learned about back at WWDC. If you’re eager to try out all the new features (some of which are outlined below), the company is offering a public beta that you can install right now.This is the first public beta Apple is offering for watchOS. Typically, it’s simple to get an early look at macOS, iOS, and iPadOS software, but...
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Skip the trying on and go straight to rocking that outfit. (Godisable Jacob / Pexels/)As a lazy homebody, I shop for almost everything online—except clothes. Call me old-fashioned, but I prefer to go to the mall, try on multiple sizes, and visit a few stores to find the perfect fit.But things are not so simple in the midst of a pandemic. Some states, like California and Florida, are suffering from strong infection surges and authorities are asking people to stay home. And even in places where stores...
Wed Aug 12, 2020 19:16
Snap shots anywhere. (Thom Holmes via Unsplash/)Whether you’re tackling a hike through the mountains or a surf on the ocean, rugged cameras are built to capture it all. They’re perfect for the toughest of environments, with waterproof, shockproof, and freeze-proof designs that make them the ultimate adventure companion. We found some of the most durable cameras on the market, which promise to shoot vibrant pictures and withstand intense exploration.Comes with five underwater shooting modes. (Amazon/)Capture...
Wed Aug 12, 2020 16:50
All of time and space; everywhere and anywhere; every star that ever was. Where do you want to start? (Shot by Cerqueira via Unsplash/)Like a great film or television show, the best games are often a form of escapism from everyday life. And there’s no better way to escape than into the actual stars—the unexplored frontier of outer space. There are games for all types of players, from intergalactic conquest to terraforming the red planet of Mars to choosing alien factions and fighting over territory.We’ve...
Wed Aug 12, 2020 15:56
Relax in the shade. (Claudia Altamimi via Unsplash/)Hot, sweaty weather are only made better with a cool drink and plenty of shade. Investing in a backyard umbrella means so many more comfy days spent outside—minus all the stickiness and heat exhaustion. They’ll add a splash of color to your outdoor area and some of them even include LED lights. We found a few of the sturdiest, most weather-resistant umbrellas out there for the ultimate cool-off experience.Fits 4-6 chairs underneath. (Amazon/)The...
Wed Aug 12, 2020 15:45
Achieve shots from great heights. (Arnold Dogelis via Unsplash/)If you’re in the market for cinematic, aerial footage that will capture your activities – whether it’s a casual day at the beach or an adventurous hike in the mountains – pro drones have you covered. These high-quality cameras fly overhead, taking sweeping pictures and video as they go. Get ready to snag some enviable shots that’ll have people saying, “How did you do that?!”Capture crisp shots in low-light settings. (Amazon/)Shoot vivid...
Wed Aug 12, 2020 15:39
Mauritius' clear waters are currently muddied by oil (bg62/Pixabay/)When a huge freighter aground on the coast of Mauritius cracked open last Thursday, August 6, David Sauvage took immediate action. He called up his friends and team members from Rezistans ek Alternativ, a local group of environmental and political activists, and got to work. The born and bred Mauritian, who is a software engineer by day, knew that they could not wait for a government-run clean up. After all, the Japanese carrier...
Wed Aug 12, 2020 15:49
Related Articles SHAMAN: a user-friendly website for metataxonomic analysis from raw reads to statistical analysis. BMC Bioinformatics. 2020 Aug 10;21(1):345 Authors: Volant S, Lechat P, Woringer P, Motreff L, Campagne P, Malabat C, Kennedy S, Ghozlane A Abstract BACKGROUND: Comparing the composition of microbial communities among groups of interest (e.g., patients vs healthy individuals) is a central aspect in microbiome research. It typically...
Wed Aug 12, 2020 15:09
Related Articles ImmunoGlobe: enabling systems immunology with a manually curated intercellular immune interaction network. BMC Bioinformatics. 2020 Aug 10;21(1):346 Authors: Atallah MB, Tandon V, Hiam KJ, Boyce H, Hori M, Atallah W, Spitzer MH, Engleman E, Mallick P Abstract BACKGROUND: While technological advances have made it possible to profile the immune system at high resolution, translating high-throughput data into knowledge of immune...
Wed Aug 12, 2020 15:09
Related Articles The impact of a hands-on arthrocentesis workshop in undergraduate medical education. BMC Med Educ. 2020 Aug 10;20(1):260 Authors: Ladurner A, Nijman T, Gill TK, Smitham PJ Abstract BACKGROUND: To evaluate the impact of a training programme for arthrocentesis on procedural skills enhancement and self-confidence in medical students. METHODS: Participants were provided a structured workshop on injection models. A self-confidence...
Wed Aug 12, 2020 14:28
Related Articles Proficiency testing for identifying underperforming students before postgraduate education: a longitudinal study. BMC Med Educ. 2020 Aug 10;20(1):261 Authors: Andreou V, Eggermont J, Gielis G, Schoenmakers B Abstract BACKGROUND: Efficient selection of medical students in GP training plays an important role in improving healthcare quality. The aim of this study was to collect quantitative and qualitative validity evidence of...
Wed Aug 12, 2020 14:28
Related Articles Socio-demographic correlates of first dose of measles (MCV1) vaccination coverage in India. BMC Public Health. 2020 Aug 10;20(1):1221 Authors: Panda BK, Mishra S, Awofeso N Abstract BACKGROUND: Between 2010 and 2018, measles-related mortality had halved in India mainly with effective measles vaccination campaigns and widespread coverage across the states and population subgroups. Despite the commendable vaccination coverage,...
Wed Aug 12, 2020 13:27
Related Articles Perspectives of HIV-positive and -negative people who use drugs regarding the criminalization of HIV non-disclosure in Canada: a qualitative study. BMC Public Health. 2020 Aug 10;20(1):1220 Authors: Ng C, Chayama KL, Krüsi A, Small W, Knight R Abstract BACKGROUND: While previous research has identified how criminalization of HIV non-disclosure can have deleterious effects on those living with HIV, the perspectives of people...
Wed Aug 12, 2020 13:27
Related Articles The association between protection motivation and hepatitis b vaccination intention among migrant workers in Tianjin, China: a cross-sectional study. BMC Public Health. 2020 Aug 10;20(1):1219 Authors: Liu C, Nicholas S, Wang J Abstract BACKGROUND: Migrant workers are a susceptible population to the hepatitis b virus (HBV) and a vulnerable spot in China's immunization procedures. There is no free HBV immunization program for...
Wed Aug 12, 2020 13:27
Related Articles SPARC is a key mediator of TGF-β-induced renal cancer metastasis. J Cell Physiol. 2020 Aug 11;: Authors: Bao JM, Dang Q, Lin CJ, Lo UG, Feldkoren B, Dang A, Hernandez E, Li F, Panwar V, Lee CF, Cen JJ, Guan B, Margulis V, Kapur P, Brekken RA, Luo JH, Hsieh JT, Tan WL Abstract Aberrant expression of transforming growth factor-β1 (TGF-β1) is associated with renal cell carcinoma (RCC) progression by inducing cancer metastasis....
Wed Aug 12, 2020 15:57
Related Articles The role of NOX4 in pulmonary diseases. J Cell Physiol. 2020 Aug 11;: Authors: Li ZM, Xu SY, Feng YZ, Cheng YR, Xiong JB, Zhou Y, Guan CX Abstract Nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4) is a subtype of the NOX family, which is mainly expressed in the pulmonary vasculature and pulmonary endothelial cells in the respiratory system. NOX4 has unique characteristics, and is a constitutively active enzyme that...
Wed Aug 12, 2020 15:57
Related Articles Long noncoding RNA HNF1A-AS1 regulates proliferation and apoptosis of glioma through activation of the JNK signaling pathway via miR-363-3p/MAP2K4. J Cell Physiol. 2020 Aug 10;: Authors: Bi Y, Mao Y, Su Z, Du J, Ye L, Xu F Abstract Long noncoding RNAs (lncRNAs) have been proven to exert important functions in the various biological processes of human cancers. It has been reported that lncRNA HNF1 homeobox A antisense RNA 1 (HNF1A-AS1)...
Wed Aug 12, 2020 15:57
Related Articles Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status. J Physiol. 2020 Aug 11;: Authors: Ohno Y, Satoh K, Shitara A, Into T, Kashimata M Abstract KEY POINTS: Few reports have explored the possibility of involvement of non-inflammatory factors in lacrimal hyposecretion in Sjögren's syndrome (SS). RNA-seq analysis revealed that only 4 genes, including...
Wed Aug 12, 2020 15:45
26 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Proc Natl Acad Sci U S A"[jour] These pubmed results were generated on 2020/08/12PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Aug 12, 2020 14:27
Οι πολυεστιακοί φακοί επαφής δεν είναι μόνο για τα γερασμένα μάτια που δεν μπορούν να διαβάσουν καλά. Τα παιδιά που φοράνε τέτοιους φακούς επαφής έχουν σημαντικά πιο αργή εξέλιξη της μυωπίας τους, σύμφωνα με μία νέα αμερικανική κλινική δοκιμή. Τις τελευταίες δεκαετίες, η μυωπία -στην οποία τα μάτια αποκτούν για μυστηριώδεις λόγους επίμηκες σχήμα- εμφανίζει αυξητική τάση διεθνώς. Έως το 2050 εκτιμάται ότι πάνω από τους μισούς ανθρώπους (το 54%) θα έχουν μυωπία, ενώ μεγάλη μυωπία πάνω από πέντε βαθμούς...
Wed Aug 12, 2020 10:35
Νέα έρευνα βρήκε ότι δίνοντας μεγαλύτερη σημασία στις εσωτερικές αισθήσεις του σώματός μας μπορούμε να αυξήσουμε την εκτίμηση που νιώθουμε για αυτό. Πιο αναλυτικά, η μελέτη που δημοσιεύθηκε στο Body Image επικεντρώθηκε στην παρεμβολή του γαστρεντερικού συστήματος, δηλαδή τα συναισθήματα της πείνας ή της πληρότητας που προέρχονται από το έντερο. Οι επιστήμονες με επικεφαλής την Jennifer Todd από το Πανεπιστήμιο Anglia Ruskin πραγματοποίησαν ένα πείραμα με 191 ενήλικες σε Βρετανία και Μαλαισία, κατά...
Wed Aug 12, 2020 09:30
Επιστήμονες στο Πανεπιστήμιο του Έξετερ στο Ηνωμένο Βασίλειο και το Ερευνητικό Ινστιτούτο Βορειοδυτικής Ακτής του Ειρηνικού που εδρεύει στο Σιάτλ των ΗΠΑ ανέπτυξαν μία πολυπαραγοντική μέθοδο για την καλύτερη πρόγνωση του διαβήτη τύπου 1 στα νεογνά, στη βάση της γενετικής, κλινικών παραγόντων όπως οικογενειακό ιστορικό διαβήτη, καθώς και του προσδιορισμού των αντισωμάτων νησιδίων -βιοδείκτες γνωστοί για τη συσχέτισή τους με τον διαβήτη τύπου 1. Το μοντέλο πρόγνωσης βασίστηκε στην ανάλυση δεδομένων...
Wed Aug 12, 2020 08:50
Νέα έρευνα από κοινωνιολόγο του Πανεπιστημίου του Buffalo παρέχει αξιόπιστα στοιχεία για την καλύτερη κατανόηση της σχέσης ανάμεσα στις εγκληματικές συμπεριφορές και στον εθισμό στα τυχερά παιχνίδια. «Βρήκαμε ότι δεν ισχύει τόσο ότι ο εθισμός στα τυχερά παιχνίδια προκαλεί το έγκλημα, αλλά ότι τα ίδια βασικά χαρακτηριστικά που συμβάλλουν στην πρόβλεψη των πιθανοτήτων για τον εθισμό αυτό, προβλέπουν επίσης την τάση προς το έγκλημα», αναφέρει ο Christopher Dennison, επίκουρος καθηγητής κοινωνιολογίας...
Wed Aug 12, 2020 08:20
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