The objective of this study was to evaluate the ability of endothelial biomarkers to early predict clinical deterioration of patients admitted to the emergency department (ED) with a suspected sepsis. This was...
Wed Aug 12, 2020 03:00
The Journal of Antibiotics, Published online: 13 August 2020; doi:10.1038/s41429-020-0360-zStreptomyces marianii sp. nov., a novel marine actinomycete from southern coast of India
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Abstract Activating transcription factor 2(ATF2), a transcription factor belonging to the AP-1 family, plays an important role in inflammation. However, its biological functions and underlying molecular mechanisms in rheumatoid arthritis (RA) remain unclear. Western blot and immunohistochemistry were used to identify the expression of ATF2 and Sprouty2(SPRY2) in RA synovial tissues. SW982 cells were stimulated by TNF-α to establish an...
Wed Aug 12, 2020 03:00
Abstract Local joint inflammation plays an important role in the pathogenesis of temporomandibular joint (TMJ) osteoarthrosis (TMJOA). Yohimbine, an alpha-2 adrenergic receptor antagonist, possesses anti-inflammatory properties; however, the ability of Yohimbine to protect against TMJOA-associated chondrocyte inflammation remains unclear. We conducted in vitro and in vivo analyses to investigate whether Yohimbine could ameliorate TMJOA-induced chondrocyte inflammation and to elucidate...
Wed Aug 12, 2020 03:00
From 2007 to 2009, a devastating yellow fever virus outbreak nearly decimated brown and black and gold howler monkey populations at El Parque El Piñalito in northeastern Argentina. An international research team tested if howlers who survived the outbreak had any genetic variations that may have kept them alive. In brown howlers, they found two mutations on immune genes that resulted in amino acid changes in the part of the protein that detects the disease.
Wed Aug 12, 2020 22:36
Mucosal Immunology, Published online: 12 August 2020; doi:10.1038/s41385-020-00337-8Boosting MAIT cells as immunotherapy: context is everything
Wed Aug 12, 2020 03:00
Abstract Objectives The need of a standardized reporting scheme and language, in imaging of COVID-19 pneumonia, has been welcomed by major scientific societies. The aim of the study was to build the reporting scheme of chest CT in COVID-19 pneumonia. Methods A team of experts, of the Italian Society of Medical and Interventional Radiology...
Wed Aug 12, 2020 03:00
Abstract Radiomics is a quantitative approach to medical imaging, which aims at enhancing the existing data available to clinicians by means of advanced mathematical analysis. Through mathematical extraction of the spatial distribution of signal intensities and pixel interrelationships, radiomics quantifies textural information by using analysis methods from the field of artificial intelligence. Various studies from different fields in imaging have been published so far, highlighting...
Wed Aug 12, 2020 03:00
The biomarkers commonly utilized in diagnostic evaluations of kidney disease suffer from low sensitivity, especially in the early stages of renal damage. On the other hand, obtaining a renal biopsy to augment clinical decision making can lead to potentially serious complications. In order to overcome the shortcomings of currently available diagnostic tools, recent studies suggest that exosomes, cell-secreted extracellular vesicles containing a large array of active molecules to facilitate cell-to-cell...
Wed Aug 12, 2020 16:50
Early leaf spot (ELS) caused by Cercospora arachidicola (Hori) is a serious foliar disease in peanut worldwide, which causes considerable reduction of yield. Identification of resistance genes is important for bo...
Tue Aug 11, 2020 03:00
The Society for the Anthropology of Food and Nutrition announces its three annual student awards for research and writing. Due to the turmoil and confusion of the last few months, we have delayed the deadlines for all three awards. They are now due September 18, 2020. Students who have written on the topic of food and nutrition are encouraged to apply for the Thomas Marchione Award and the Christine Wilson Award. Graduate students in the process of conducting research are encouraged to apply for...
Wed Aug 12, 2020 18:30
Publication date: Available online 11 August 2020Source: Médecine & DroitAuthor(s): Bruno Py
Wed Aug 12, 2020 18:24
Publication date: Available online 11 August 2020Source: Sleep MedicineAuthor(s): Yuan-Yuan Weng, Xu Lei, Jing Yu
Wed Aug 12, 2020 16:15
Publication date: August 2020Source: Sleep Medicine, Volume 72Author(s):
Wed Aug 12, 2020 16:15
Publication date: Available online 12 August 2020Source: Clinics in Plastic SurgeryAuthor(s): Anita T. Mohan, Lin Zhu, Aparna Vijayasekaran, Michel Saint-Cyr
Wed Aug 12, 2020 15:35
Publication date: Available online 12 August 2020Source: Clinics in Plastic SurgeryAuthor(s): Chao Chen, Zeng Tao Wang, Li Wen Hao, Lin Feng Liu
Wed Aug 12, 2020 15:35
Related Articles Implant-supported fixed and removable prostheses in the fibular mandible. Int J Implant Dent. 2020 Aug 11;6(1):44 Authors: Nguyen TTH, Eo MY, Myoung H, Kim MJ, Kim SM Abstract BACKGROUND: To restore the health-related quality of life (HRQoL) of patients who underwent jaw resection and reconstruction surgery, dental rehabilitation is an essential procedure and also one of the most challenging for oral and maxillofacial surgeons....
Wed Aug 12, 2020 15:21
Related Articles Analysis of weekend effect on mortality by medical specialty in Helsinki University Hospital over a 14-year period. Health Policy. 2020 Jul 31;: Authors: Tolvi M, Mattila K, Haukka J, Aaltonen LM, Lehtonen L Abstract BACKGROUND: The weekend effect, the phenomenon of patients admitted at the weekend having a higher mortality risk, has been widely investigated and documented in both elective and emergency patients. Research on...
Wed Aug 12, 2020 15:16
Related Articles Computer-assisted surgery for replacement of the temporomandibular joint with customized prostheses: can we validate the results? Oral Maxillofac Surg. 2020 Sep;24(3):317-325 Authors: Boccalatte LA, Nassif MG, Figari MF, Gómez NL, Argibay MC, Mancino AV, Ritacco LE Abstract PURPOSE: Replacing the temporomandibular joint poses an important challenge to maxillofacial surgeons, and for certain disorders, it represents the treatment's...
Wed Aug 12, 2020 15:16
ABSTRACT Background Traditionally patients are seen by an Ear Nose Throat (ENT) surgeon prior to Allied Health referral for treatment of swallowing, voice, hearing, and dizziness. Wait‐times for ENT consultations often exceed those clinically recommended. We evaluated the service impact of five Allied Health Primary Contact clinics (AHPC‐ENT) on wait‐times and access to treatment. Setting Ametropolitan Australian University Hospital outpatient ENT Department. Participants We created...
Tue Aug 11, 2020 11:19
Related Articles Lost to follow up: Exploring patients who initially fail cochlear implant evaluation. Cochlear Implants Int. 2020 Aug 10;:1-6 Authors: Schauwecker N, Tolisano AM, Hunter JB Abstract Objective: To explore variables predicting which individuals return for repeat cochlear implantation (CI) evaluation after initially not qualifying. Study design: Retrospective chart review. Setting: University CI program. Patients: Adults undergoing...
Wed Aug 12, 2020 13:59
Abstract Airflow obstruction in people with asthma, similar to COPD, may interfere with swallowing, increasing the risk of food or liquid entrance into the lower airways, and favoring the uncontrolled disease. To describe the complaints and findings of the oropharyngeal swallowing mechanisms in patients with mild and severe asthma, a cross-sectional study was performed. A total of 135 participants with asthma were studied, of whom 97 had severe asthma and 38 had mild asthma. All...
Wed Aug 12, 2020 03:00
Publication date: Available online 12 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Constanza San Martín Valenzuela, Lirios Dueñas Moscardó, Juan López Pascual, Pilar Serra Añó, José M. Tomás
Wed Aug 12, 2020 13:08
Publication date: Available online 12 August 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Yanan Zheng, Ying Zhang, Hongli Li, Lei Qiao, Weijie Fu, Long Yu, Gaiyan Li, Jianzhong Yang, Weidong Ni, Zhijie Yong, Yanmin Wang, Hang Fan
Wed Aug 12, 2020 13:08
Abstract Trade‐offs in the time and energy allocated to different functions, such as reproductive activities, can be driven by alterations in condition which reduce resources, often in response to extrinsic factors such as pathogens or parasites. When individuals are challenged by a pathogen they may either reduce reproduction as a cost of increasing defence mechanisms, or alternatively, modify reproductive activities so as to increase fecundity thereby minimizing the fitness costs of earlier death,...
Tue Aug 11, 2020 18:15
Abstract Sleep and circadian rhythms are considered to be important determinants of mental and physical health. Epidemiological studies have established the contribution of self‐reported sleep duration, sleep quality and chronotype to health outcomes. Mental health and sleep problems are more common in women and men are more likely to be evening types. Few studies have compared the relative strength of these contributions and few studies have assessed these contributions separately in men and women....
Tue Aug 11, 2020 22:00
Abstract Restless legs syndrome is a relatively common neurological disorder in adults. In childhood, however, its prevalence and genetic contribution are still largely unknown. The objectives of this study were to assess the prevalence of restless legs syndrome (RLS) during childhood and adolescence in a large population‐based cohort and evaluate the degree of association with parental history. Data from a large, prospective longitudinal cohort from the Quebec Longitudinal Study of Child Development...
Tue Aug 11, 2020 20:45
Key points Few reports have explored the possibility of involvement of non‐inflammatory factors in lacrimal hyposecretion in Sjögren's syndrome (SS). RNA‐seq analysis revealed that only 4 genes, including arginase 1, were downregulated in the lacrimal gland of SS model male mice (NOD mice) after onset of lacrimal hyposecretion and dacryoadenitis. Even in non‐dacryoadenitis type NOD mice, tear secretion and arginase 1 expression remained low. An arginase 1 inhibitor reduced tear secretion and...
Tue Aug 11, 2020 16:30
Abstract Purpose To investigate the effect of experimental traumatic occlusion (ETO) induced by metal crowns on alveolar bone loss. Materials and Methods Metal crowns were custom‐made for the lower first molars with occlusal discrepancy of 0.4 and 0.7 mm from the maximum intercuspation. Thirty‐six animals were randomly divided into three groups (n = 12 animals per group): 0.4‐mm hyperocclusion group, 0.7‐mm hyperocclusion group and the sham group (no metal crown). Twenty‐eight days after...
Wed Aug 12, 2020 10:57
ABSTRACT Purpose The additions of zirconium oxide nanoparticles (nano‐ZrO2) to denture base materials have produced nanocomposites with satisfactory properties, although there is a lack of research investigating the effects of denture cleansers on these materials. This study aimed to evaluate the effect of denture cleansers on the flexural strength of denture base materials modified with nano‐ZrO2. Materials and Methods A total of 270 specimens were fabricated from pure and nano‐ZrO2 reinforced...
Tue Aug 11, 2020 21:04
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