Publication date: Available online 12 August 2020Source: American Journal of OtolaryngologyAuthor(s): Bülent Ulusoy, Abdullah Tunçez, Osman Gül, Hüseyin Tezcan, Ömer Erdur, Hüsamettin Vatansev, Esra Paydaş Hataysal, Muslu Kazım Körez, Bahar Çolpan
Wed Aug 12, 2020 16:18
Publication date: Available online 12 August 2020Source: American Journal of OtolaryngologyAuthor(s): Vivian F. Kaul, Kevin Chow, Santino Luigi Estrera, Zachary G. Schwam, George B. Wanna
Wed Aug 12, 2020 16:18
Publication date: Available online 12 August 2020Source: American Journal of OtolaryngologyAuthor(s): Kumiko Tanaka, Atsunobu Tsunoda, Miri Tou, Kenji Sonoda, Shinpei Arai, Takashi Anzai, Fumihiko Matsumoto
Wed Aug 12, 2020 16:18
Publication date: Available online 11 August 2020Source: American Journal of OtolaryngologyAuthor(s): Richard H. Law, Alvin B. Ko, Lamont R. Jones, Edward L. Peterson, John R. Craig, Robert H. Deeb
Wed Aug 12, 2020 16:18
Publication date: Available online 11 August 2020Source: American Journal of OtolaryngologyAuthor(s): Lian Cheng, Yuan Le, Hui Yang, Xiangyu Zhou
Wed Aug 12, 2020 16:18
Publication date: Available online 11 August 2020Source: American Journal of OtolaryngologyAuthor(s): Ossama M. Mady, Hala S. Elozairy, Eman M. Wady
Wed Aug 12, 2020 16:18
Publication date: Available online 11 August 2020Source: American Journal of OtolaryngologyAuthor(s): Emre Soylemez, Banu Mujdeci
Wed Aug 12, 2020 16:18
Publication date: Available online 11 August 2020Source: American Journal of OtolaryngologyAuthor(s): Rebecca A. Compton, Eleni K. Konstantinou, Mitesh K. Kapadia, Andrew R. Scott
Wed Aug 12, 2020 16:18
Publication date: Available online 11 August 2020Source: American Journal of OtolaryngologyAuthor(s): Pasquale Viola, Davide Pisani, Alfonso Scarpa, Claudia Cassandro, Carla Laria, Teodoro Aragona, Marco Ciriolo, Lucrezia Spadera, Massimo Ralli, Michele Cavaliere, Maurizio Iengo, Giuseppe Chiarella
Wed Aug 12, 2020 16:18
ABSTRACT Background Traditionally patients are seen by an Ear Nose Throat (ENT) surgeon prior to Allied Health referral for treatment of swallowing, voice, hearing, and dizziness. Wait‐times for ENT consultations often exceed those clinically recommended. We evaluated the service impact of five Allied Health Primary Contact clinics (AHPC‐ENT) on wait‐times and access to treatment. Setting Ametropolitan Australian University Hospital outpatient ENT Department. Participants We created...
Tue Aug 11, 2020 11:19
Condition: Head and Neck CancerIntervention: Drug: Panitumumab-IRDye800Sponsor: University of Alabama at BirminghamNot yet recruiting
Wed Aug 12, 2020 17:26
Condition: Head and Neck Cancer / Esophageal Squamous CancerIntervention: Drug: Capecitabine, CamrelizumabSponsor: Ruijin HospitalRecruiting
Wed Aug 12, 2020 17:26
Conditions: Esophagogastric Tumors; Gastric Cancer; Gastric Tumor; Esophageal Cancer; Esophageal Neoplasms; Esophageal Tumor; GastroEsophageal Cancer; Gastroesophageal Junction Adenocarcinoma; Gastroesophageal Junction Tumor; Gastroesophageal Junction CancerInterventions: Drug: Trastuzumab; Drug: PembrolizumabSponsor: Memorial Sloan Kettering Cancer CenterRecruiting
Wed Aug 12, 2020 17:26
Condition: Nasopharyngeal CarcinomaIntervention: Drug: LMBP2-specific TCR-T cell with IL12 auto-secreting elementSponsors: Xinqiao Hospital of Chongqing; TCRCure Biopharma LtdNot yet recruiting
Wed Aug 12, 2020 17:26
Conditions: Cancer of Head and Neck; Lung Cancer, Nonsmall Cell; Small-cell Lung Cancer; Urothelial Carcinoma; Gastroesophageal Junction Adenocarcinoma; Cervical Cancer; Esophageal Squamous Cell Carcinoma; Triple Negative Breast Cancer; Hepatocellular Carcinoma; Renal Cell Carcinoma; Colorectal CancerIntervention: Diagnostic Test: OncoPrism™ assaySponsors: Cofactor Genomics, Inc.; Curebase, Inc.Recruiting
Wed Aug 12, 2020 17:26
Conditions: Advanced Malignant Solid Neoplasm; Clinical Stage III Gastroesophageal Junction Adenocarcinoma; Clinical Stage IV Gastroesophageal Junction Adenocarcinoma; Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma; Clinical Stage IVB Gastroesophageal Junction Adenocarcinoma A; Locally Advanced Colorectal Carcinoma; Locally Advanced Gastroesophageal Junction Adenocarcinoma; Metastatic Colorectal Adenocarcinoma; Metastatic Gastroesophageal Junction Adenocarcinoma; ...
Wed Aug 12, 2020 17:26
Abstract The high mobility group AT‐hook 2 (HMGA2) gene encodes a transcription factor that is expressed during embryonic development but down‐regulated in adult tissues. Its re‐expression in adult tissues is often associated with tumorigenesis. In this study, we found that HMGA2 is highly expressed in human cutaneous squamous cell carcinoma (SCC) cell lines and primary SCC tumors, but not in adjacent normal skin. In non‐ultraviolet (UV)‐irradiated mouse skin, baseline Hmga2 expression was detected...
Tue Aug 11, 2020 18:14
Abstract Nicotinic acetylcholine receptors (nAChRs) are members of the superfamily of neurotransmitter‐gated ion channels. The natural ligand for nAChRs is the endogenous neurotransmitter acetylcholine. Among the nAChRs is the α7nAChR. It is not only expressed by neural tissues but also in the skin. A number of different resident cutaneous cell types including epidermal keratinocytes, sebocytes and dermal fibroblasts express functional α7nAChR. Moreover, cells of the immune system such as lymphocytes,...
Tue Aug 11, 2020 18:04
Abstract Generalized pustular psoriasis (GPP) is a rare, inflammatory skin disease characterized by recurrent flares of pustulation accompanied by systemic symptoms. Due to its acuteness, sufficient diagnosis and treatment is essential, but often faces challenges. We recently overviewed various treatment options of GPP utilizing established therapies in psoriasis vulgaris (PsO). Although there is a pathogenic relation to PsO, more and more evidence suggests a predominant involvement of the innate...
Tue Aug 11, 2020 16:54
Abstract Background Psoriasis is a chronic inflammatory disorder with cutaneous and systemic manifestations and substantial negative effects on patients’ quality of life. MicroRNAs (miRNAs) are post‐transcriptional regulators of gene expression that play a role in the pathogenesis of psoriasis. Previously studies, from others and by us, highlighted specific miRNAs that are dysregulated in psoriatic lesions. MicroRNA‐197‐3p (miR‐197) expression is down‐regulated in psoriatic lesions compared to...
Tue Aug 11, 2020 16:50
Abstract The cell dynamics and cell origin for anagen hair follicle (HF) repair following chemotherapeutic injury are unclear. We first mapped the HF response to cyclophosphamide (CYP) at natural anagen VI in mice. We found that 30 to 60 mg/kg of CYP lead to dose‐dependent HF dystrophy that was spontaneously repaired with anagen resumption while 120 mg/kg of CYP prematurely induced catagen/telogen entry. To explore how anagen HF repair is achieved in the dystrophic anagen pathway, we analyzed the...
Tue Aug 11, 2020 13:39
Related Articles Tumor, host and surgery related factors predisposing to cranial nerve deficits after surgical treatment of parapharyngeal space tumors. Eur Arch Otorhinolaryngol. 2020 Aug 10;: Authors: Rzepakowska A, Osuch-Wójcikiewicz E, Żurek M, Durmaj A, Niemczyk K Abstract PROPOSE: Identification of relevant features acquired on preoperative evaluation of parapharyngeal space (PPS) tumors or related to the performed surgical approach that...
Wed Aug 12, 2020 14:42
Spontaneous salivary otorrhea is a rare presentation only previously documented twice in literature where parotid salivary secretions are found in the external auditory canal. Conventional treatment of spontan...
Wed Aug 12, 2020 03:00
There have been extensive paradigm shifts in the management of perioperative analgesia when it comes to surgical patients over the past 3 decades. In the late 1990s, several private and government-based organizations raised recognition of pain as an undertreated “vital sign,” a policy that has led to unintended consequences, including the rise of the contemporary opioid epidemic.
Wed Aug 12, 2020 03:00
These articles on leadership, diversity, and inclusion are being written, reviewed, and published in undoubtedly turbulent times. We are forging forward despite the uncertainties inherent in a global pandemic while simultaneously confronting hard realities about our society and embedded systemic issues. For example, the stark racial disparities, and disproportionate burden borne by minority populations, in COVID-19 outcomes are headline news. Conversations about how health is not biologically predetermined,...
Wed Aug 12, 2020 03:00
Publication date: Available online 11 August 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): R. Baudouin, F. Simon, F. Denoyelle, V. Couloigner, S. Irtan
Wed Aug 12, 2020 13:49
Publication date: Available online 12 August 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Chandni Jain, Marc Levin, Heather Hardy, Forough Farrokhyar, Diane Reid
Wed Aug 12, 2020 16:51
Publication date: Available online 12 August 2020Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Barbara Cristina da Silva Rosa, Carla Patrícia Hernandez Alves Ribeiro César, Luiz Renato Paranhos, Raphaela Barroso Guedes-Granzotti, Doris Ruthy Lewis
Wed Aug 12, 2020 16:51
Abstract BackgroundThe improvement of the steer‐ability and controllability of catheters is highly required because catheter‐based interventional diagnosis and therapy have become increasingly popular. However, active catheters are often complex and expensive.MethodsThis paper attempts to control catheter tip by a twisted string actuator. Experiments are carried out to analyze the full actuation and bending characteristics of the active catheter.ResultsIt is indicated that the expected bending motion...
Tue Aug 11, 2020 22:28
Objective Sjögren syndrome is a systemic inflammatory disease causing gland dysfunction. Few (and contradictory) reports on the mucosal effects of Sjögren syndrome have appeared. Here, we objectively demonstrate nasal dryness in Sjögren syndrome patients and explore the effect of such dryness on olfaction. Methods Thirty‐four consecutive patients with primary Sjögren syndrome were enrolled in this cross‐sectional study. The control group consisted of 21 age‐ and sex‐matched volunteers. Medical...
Tue Aug 11, 2020 20:53
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