Objectives. The aim of the study was to determine the quantitative and qualitative surface structure of contemporary RBCs in posterior teeth reconstructions: regular viscosity bulk fill and conventional composites, obtained after two-stage polishing procedure. Materials and Methods. Four conventional nanohybrid composites (Tetric EvoCeram, GrandioSO, Filtek Z550, and Ceram·X Mono) and four regular viscosity bulk fill composites (Tetric EvoCeram Bulk Fill, X-tra fil, Filtek Bulk Fill Posterior, and...
Wed Aug 12, 2020 17:20
Objective. To explore multiscale integrated analysis methods in identifying key regulators of esophageal cancer (ESCA). Methods. We downloaded the ESCA dataset from The Cancer Genome Atlas (TCGA) database, which contained RNA-seq data, miRNA-seq data, methylation data, and clinical phenotype information. Then, we combined ESCA-related genes from the NCBI-GENE and OMIM databases and RNA-seq dataset from TCGA to analyze differentially expressed genes (DEGs). Meanwhile, differentially expressed miRNAs...
Wed Aug 12, 2020 17:05
Hypertensive white matter lesion (WML) is one of common causes of vascular cognitive impairment. In this study, we aimed to investigate the effect of rosuvastatin on cognitive impairment and its underlying mechanisms in chronic hypertensive rats. From the 8th week after establishment of stroke-prone renovascular hypertensive rats (RHRSPs), rosuvastatin (10 mg/kg) or saline as a control was administrated once daily for consecutive 12 weeks by gastric gavage. Cognitive function was assessed with the...
Wed Aug 12, 2020 16:35
Background. Since the first reports of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in December 2019 in Wuhan, China, the virus has spread to other parts of China and across the world. Although a few studies have assessed the clinical course of coronavirus disease 2019 (COVID-19), the changes in clinical characteristics during disease progression remain unclear. Methods. We retrospectively analyzed the clinical characteristics of 62 patients who died from COVID-19 at the...
Wed Aug 12, 2020 16:20
Purpose. This study is aimed at assessing pharmacists’ knowledge and practice of issue related to usage of psychotropic medications in elderly people, in Gondar town Northwest, Ethiopia. Methods. A cross-sectional study was conducted among pharmacists working in community, health center, and hospital pharmacies in Gondar town from March 1 to May 30, 2020. A total of 73 medication retail outlets (40 pharmacies and 33 drug stores) were included in this study. Pharmacy personnel’s knowledge and practice...
Wed Aug 12, 2020 10:50
Introduction. Glioblastoma is the most malignant grade of glioma, and it is also the most common primary tumor in the brain. Immunotherapy is a kind of precise tumor treatment. However, there are limited studies about immune-related lncRNA. This study is aimed at analyzing immune-related lncRNAs in glioblastoma and screening out prognostic factors, providing new potential targets for glioblastoma immunology research. Material and Methods. Gene expression data and clinical data of IDH wild-type with...
Wed Aug 12, 2020 10:50
To determine the conclusive integrity in the Shiraz Cohort Heart Study (SCHS) project, management began quality assurance (QA) and quality control (QC) of the collected data throughout the study end-points. The QA is a focused process that prevents and detects data collection errors and verification of intended requirements in the SCHS. The QC is a subset of QA intended to capture errors in processing data through testing and preventive processes to identify problems, defects, or intended requirements....
Wed Aug 12, 2020 10:35
Object. In this study, our aim is to evaluate the efficiency of extracorporeal shockwave therapy (ESWT) on chronic Achilles tendinopathy (CAT) with different courses of disease. Methods. The data of 66 patients with CAT received ESWT was reviewed. According to the disease courses, those cases were allocated to short-term group (ST group, symptom duration 3-6 months) and long-term group (LT group, symptom duration >6 months). Propensity scores match (PSM) method was conducted to eliminate the confound...
Wed Aug 12, 2020 10:35
Background. A number of researches focused on the study of tumors have concluded that the expression level of lncRNA NKILA was decreased in different tumors. This is an indication that NKILA might influence the start and growth of a cancer. In addition, studies have fatalities and worsening health of cancer patients is associated with a reduced level of NKILA. Results. The results are the collective screening of nine total studies which included 937 cancer patients. The prognosis of the meta-analysis...
Wed Aug 12, 2020 10:35
Abstract Angiogenesis, the development of new blood capillaries, is crucial for the wound healing process. This biological process allows the proper blood supply to the tissue, essential for cell proliferation and viability. Several biological factors modulate angiogenesis, however the vascular endothelial growth factor (VEGF) is the main one. Given the complexity of angiogenesis, in the last years, computational modelling aroused the interest of scientists since it allows to model this process...
Tue Aug 11, 2020 21:23
Abstract Numerical simulation of blood flows in patient‐specific arteries can be useful for the understanding of vascular diseases, as well as for surgery planning. In this paper, we simulate blood flows in the full cerebral artery of stroke patients. To accurately resolve the flow in this rather complex geometry with stenosis is challenging and it is also important to obtain the results in a short amount of computing time so that the simulation can be used in pre‐ and/or post‐surgery planning....
Tue Aug 11, 2020 21:09
Researchers at the UCLA Samueli School of Engineering and the Stanford School of Medicine have developed a smartwatch that uses electrochemical analysis to track levels of a drug in the body by analyzing a patient’s sweat. The system could help with finding the correct drug and dose for a given patient in order to maximize therapeutic potential and avoid side-effects. At present, most drugs are prescribed based on standard guidelines and can be tailored based on parameters such as...
Wed Aug 12, 2020 20:54
A cornerstone of the world’s response to Covid-19 has been mass testing of as many people as possible for the SARS-CoV-2 virus. The very act of taking a nasal swab can put a clinician performing it, or one nearby instructing the patient on how to do it, at risk. Now, a new robot has been unveiled by Brain Navi, a Taiwanese firm, that performs nasal swabs all on its own. It may make it possible to expand testing for the virus that causes Covid-19, while preventing its possible spread at the...
Wed Aug 12, 2020 17:28
Tuberculosis (TB) represents a health problem in Colombia, and its control is focused on the search for contacts and treatment of TB cases underscoring the role of latent tuberculosis infection (LTBI) as a reservoir of Mycobacterium tuberculosis. The burden of LTBI in Colombia is unknown. We aimed to estimate the prevalence of LTBI and identify the associated risk factors. In this cross-sectional study, we recruited participants from four health care centers in Cali, Colombia. The participants were...
Wed Aug 12, 2020 03:00
Biological systems, at all scales of organisation from nucleic acids to ecosystems, are inherently complex and variable. Biologists therefore use statistical analyses to detect signal among this systemic noise. Statistical models infer trends, find functional relationships and detect differences that exist among groups or are caused by experimental manipulations. They also use statistical relationships to help predict uncertain futures. All branches of the biological sciences now embrace the possibilities...
Wed Aug 12, 2020 03:00
Many flower visitors engage in floral larceny, a suite of so-called ’illegitimate’ visits in which foragers take nectar without providing pollination services. The data on prevalence of illegitimate visits among hummingbirds, as well as the total proportion of foraging and diet that such visits comprise is broadly lacking. Here, we report the occurrence of nectar larceny in the two currently recognized species of trainbearers and analyze the proportion of plant visits categorized by mode of interaction...
Wed Aug 12, 2020 03:00
Background An extensive radiation can be inferred among balaenopterid mysticetes in the last 10 million years based on a rich fossil record. Many extinct genera and species have been established in the past by the study of fossil rorquals from northern and southern hemispheres. In many cases, the new fossils are used to create new genera. However, in very recent times, new species of known genera have been described that help our understanding of the speciation processes and the biogeography of...
Wed Aug 12, 2020 03:00
Background In clinical research, the ability to properly analyze data is a necessary skill that cannot be learned simply by listening to lectures. Interactive classes, such as Peer Instruction (PI), are required to help medical students understand the concept of epidemiology for future valid research. In PI lectures, ConcepTests are conducted to confirm and deepen students’ understanding of the lecture material. Although it is important to evaluate PI lectures, there have been no...
Wed Aug 12, 2020 03:00
Heavy metals are of public concern in aquatic ecosystems due to their growing release from industries and mining activities. This study investigated the sources, temporal-spatial distributions and water quality of dissolved heavy metals (Mn, Co, Al, Ni, Ba, V, Sb, Fe, Sr) in the Lake Aha watershed, an area under the influence of sewage and acid mining drainage. These heavy metals displayed significant spatial and temporal variabilities. The water quality index results (WQI values ranged from 3.21...
Wed Aug 12, 2020 03:00
The little known fairyfly (Hymenoptera, Mymaridae), Platystethynium (Platystethynium) triclavatum (Donev & Huber, 2002), comb. n. from Pseudocleruchus Donev & Huber, 2002, is newly recorded as an egg parasitoid of Barbitistes vicetinus Galvagni & Fontana, 1993 (Orthoptera, Tettigoniidae). This bush-cricket is endemic to northeastern Italy (mainly Euganean Hills of Veneto Region), where it has recently become an economically significant agricultural and forest pest. Data on discovery,...
Wed Aug 12, 2020 03:00
Background Monophasic Salmonella Typhimurium or S. enterica 1,4,[5],12:i:- is among the top five serotypes reported in Thailand. In this study, nineteen monophasic S. Typhimurium from the pig production chain in Chiang Mai and Lamphun provinces during 2011–2014 were sequenced and compared to a globally disseminated clone. Isolates were probed in silico for the presence of antimicrobial resistance genes and Salmonella virulence factors, including Pathogenicity Islands. Results All isolates...
Wed Aug 12, 2020 03:00
The low temperature in spring is a meteorological problem in wheat production because it leads to yield reduction and alteration of wheat quality. In this study, an artificial low-temperature treatment (LTT) at the stem elongation stage was implemented to investigate the starch granule development and physical and chemical properties of wheat starch. Results showed that the agronomic traits of spike, such as spike length, spikelet number per spike, and grain number per spikelet, decreased after LTT....
Wed Aug 12, 2020 03:00
The pandemic state of COVID-19 caused by the SARS CoV-2 put the world in quarantine, led to hundreds of thousands of deaths and is causing an unprecedented economic crisis. However, COVID-19 is spreading in different rates at different countries. Here, we tested the effect of three classes of predictors, i.e., socioeconomic, climatic and transport, on the rate of daily increase of COVID-19 on its exponential phase. We found that population size and global connections, represented by countries’ importance...
Wed Aug 12, 2020 03:00
About 83% of laboratory-confirmed Middle East respiratory syndrome coronavirus (MERS-CoV) cases have emerged from Saudi Arabia, which has the highest overall mortality rate worldwide. This retrospective study assesses the impact of spatial/patient characteristics for 14-and 45-day MERS-CoV mortality using 2012–2019 data reported across Saudi regions and provinces. The Kaplan–Meier estimator was employed to estimate MERS-CoV survival rates, Cox proportional-hazards (CPH) models were applied to estimate...
Wed Aug 12, 2020 03:00
The potential for long-distance larval dispersal depends on the longevity of planktonic, free-swimming larvae and their capacity to successfully recruit to reef habitat. We present multi-year laboratory observations of the persistence of planular larvae and settlement competency over time for cohorts derived from the same parental populations of the most important Caribbean reef building coral species, Orbicella faveolata and Acropora spp. Despite variability among years/cohorts, larvae of both species...
Wed Aug 12, 2020 03:00
Publication date: Available online 11 August 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): David J. Thomson, Sue S. Yom, Hina Saeed, Issam El Naqa, Leslie Ballas, Soren M. Bentzen, Samuel T. Chao, Ananya Choudhury, Charlotte E. Coles, Laura Dover, B. Ashleigh Guadagnolo, Matthias Guckenberger, Peter Hoskin, Salma K. Jabbour, Matthew S. Katz, Somnath Mukherjee, Agata Rembielak, David Sebag-Montefiore, David J. Sher, Stephanie A. Terezakis
Wed Aug 12, 2020 18:24
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